{"title":"Easy to Take: Liquids, Dots \u0026 Powders","description":"\u003cp\u003eNo pills to swallow. B-12 Essential Trio and Everyday Liquid Sunshine are liquid drops, Triple B-12 Dots and Sleep Dots dissolve in your mouth, Relaxing Passion Flower comes as lozenges, and Calming Mag mixes into a drink.\u003c\/p\u003e","products":[{"product_id":"b12-dots-energy-nervous-support","title":"Triple B-12 Dots 1,000 mcg – Energy \u0026 Nervous System Support | 60 Dots","description":"\u003cp\u003e\u003cstrong\u003eTriple B-12 Dots are a cyanocobalamin-free vitamin B12 supplement. Each small dot provides 1,000 mcg of vitamin B12 (41,666% of the Daily Value) from three forms: 500 mcg hydroxycobalamin, 400 mcg adenosylcobalamin and 100 mcg methylcobalamin. You let one dissolve in your mouth, and each bottle holds 60 dots. Vitamin B12 supports normal energy production and a healthy nervous system.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePeople reach for B12 when they think about energy, and there's real biology behind that: your cells can't run two key energy and methylation reactions without it.† It matters most when intake or absorption runs low. B12 occurs naturally only in animal foods, so anyone eating little or no meat, fish, eggs or dairy needs another source. And the NIH advises adults over 50 to get most of their B12 from fortified foods or supplements, because many older adults don't make enough stomach acid to free B12 from food (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB12-Consumer\/\"\u003ethe NIH's consumer guide to vitamin B12\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eIf you're in your 30s or 40s and building habits now so you can still hike, lift and keep up at 75, a daily B12 dot is one of the easiest to start. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Triple B-12 Dots\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports normal energy production, as the coenzyme your mitochondria need to turn parts of protein breakdown into fuel for the energy cycle.†\u003c\/li\u003e\n\u003cli\u003eSupports healthy nervous system function.†\u003c\/li\u003e\n\u003cli\u003eSupports normal red blood cell formation and DNA synthesis.†\u003c\/li\u003e\n\u003cli\u003eSupports healthy homocysteine metabolism by helping recycle homocysteine back into methionine, working alongside folate.†\u003c\/li\u003e\n\u003cli\u003eHelps maintain healthy B12 levels for people who eat few animal foods and for adults over 50.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B12 (500 mcg hydroxycobalamin, 400 mcg adenosylcobalamin (dibencozide), and 100 mcg methylcobalamin)\u003c\/td\u003e\n\u003ctd\u003e1,000 mcg\u003c\/td\u003e\n\u003ctd\u003e41,666%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 1 Dot. The panel doesn't print a servings-per-container line; the bottle holds 60 dots, which is 60 servings at the one-dot serving size. Other ingredients: Maltodextrin, acacia, cellulose, orange juice, magnesium stearate, and natural cinnamon flavor. The label states: \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" It also states: \"Does not contain cyanocobalamin.\"\u003c\/p\u003e\n\u003ch2\u003eHow Triple B-12 Dots work\u003c\/h2\u003e\n\u003ch3\u003eVitamin B12 is a coenzyme, not a stimulant\u003c\/h3\u003e\n\u003cp\u003eB12 doesn't work like coffee. It's a helper molecule two specific enzymes can't run without. Your body uses two working forms, methylcobalamin and adenosylcobalamin, and converts other forms (like hydroxycobalamin) into those two (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB12-HealthProfessional\/\"\u003eNIH fact sheet on vitamin B12\u003c\/a\u003e). Triple B-12 Dots give you both working forms ready-made, plus hydroxycobalamin, with no cyanocobalamin.\u003c\/p\u003e\n\u003ch3\u003eAdenosylcobalamin (400 mcg): the mitochondrial form\u003c\/h3\u003e\n\u003cp\u003eAdenosylcobalamin (dibencozide is another name for it) works inside your mitochondria, the parts of your cells that make most of your energy. There it helps an enzyme called methylmalonyl-CoA mutase convert leftovers from breaking down certain amino acids into a compound that feeds straight into the energy cycle (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30693532\/\"\u003eFroese et al., 2019\u003c\/a\u003e). In plain terms, it keeps part of your protein metabolism flowing into fuel.†\u003c\/p\u003e\n\u003ch3\u003eMethylcobalamin (100 mcg): the methylation form\u003c\/h3\u003e\n\u003cp\u003eMethylcobalamin works in the main body of the cell with an enzyme called methionine synthase. That enzyme recycles homocysteine into methionine, which your body then uses to make SAMe, its most important methyl donor. The same step takes a methyl group from folate, which keeps folate moving through the cycle your cells use to build DNA (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30693532\/\"\u003eFroese et al., 2019\u003c\/a\u003e). That's why B12 and folate are usually talked about as a team.† A review of B vitamins and the brain lists these same jobs (energy production, DNA synthesis and methylation) among the ways B vitamins support normal brain function (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26828517\/\"\u003eKennedy, 2016\u003c\/a\u003e).†\u003c\/p\u003e\n\u003ch3\u003eHydroxycobalamin (500 mcg): the form your cells convert\u003c\/h3\u003e\n\u003cp\u003eHydroxycobalamin (often spelled hydroxocobalamin) makes up half of the B12 in each dot: 500 of the 1,000 mcg. Your cells convert it into either working form, so it can feed both the mitochondrial job and the methylation job (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB12-HealthProfessional\/\"\u003eNIH fact sheet on vitamin B12\u003c\/a\u003e).†\u003c\/p\u003e\n\u003ch3\u003eWhy 1,000 mcg when the Daily Value is 2.4 mcg\u003c\/h3\u003e\n\u003cp\u003eBecause you absorb only a small share of a large dose. Your gut's main B12 absorption system fills up at about 1 to 2 mcg at a time, and the NIH puts absorption at about 1.3% of a 1,000 mcg dose: roughly 13 mcg per dot, still more than five times the 2.4 mcg Daily Value (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB12-HealthProfessional\/\"\u003eNIH fact sheet on vitamin B12\u003c\/a\u003e). A systematic review of absorption studies found the same pattern with food: absorption ranged from 83% of a 3 mcg dose (from mutton) down to 4.5% of a 38 mcg dose (from liver) (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23796635\/\"\u003eDoets et al., 2013\u003c\/a\u003e).\u003c\/p\u003e\n\u003ch3\u003eWhat the research does and doesn't show\u003c\/h3\u003e\n\u003cp\u003eIt shows that intake matters. In 299 healthy adults aged 18 to 50, blood markers of B12 status leveled off once dietary intake reached about 4 to 7 mcg a day, above the 2.4 mcg Daily Value (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20071646\/\"\u003eBor et al., 2010\u003c\/a\u003e). In 2,999 adults from the Framingham Offspring Study, 8% of supplement users had blood B12 below 185 pmol\/L, compared with 20% of people who didn't take supplements; that's an observational snapshot, not a trial (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10648266\/\"\u003eTucker et al., 2000\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eIt doesn't show that B12 supplements sharpen your thinking. A systematic review of 14 randomized trials found no clear effect of B6, B12 or folic acid supplements on cognitive test scores, and the authors rated most of those trials as low quality (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17210874\/\"\u003eBalk et al., 2007\u003c\/a\u003e). And to be straight with you, none of the studies above tested this three-form blend itself. What we can tell you is exactly what's in each dot and how each form is used.\u003c\/p\u003e\n\u003ch2\u003eHow to take Triple B-12 Dots\u003c\/h2\u003e\n\u003cp\u003eThe label directions, word for word: \"One or more dots daily, as a dietary supplement. For best absorption allow dot to dissolve in mouth completely.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLet the dot dissolve fully in your mouth instead of swallowing it whole.\u003c\/li\u003e\n\u003cli\u003eThe label doesn't call for food, so pick whatever time of day you'll remember.\u003c\/li\u003e\n\u003cli\u003eOne dot is the label's serving. Not sure whether you need more? Ask your healthcare practitioner.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. Some common medications, including acid-reducing medicines, can lower B12 levels over time.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cp\u003eWe've been making supplements in Oregon since 1974. Fifty-two years in, here's how we back up what's on this label:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, the B12 included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Triple B-12 Dots gets its own certificate of analysis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e Triple B-12 Dots are made in our UL-certified cGMP facility in Mt. Angel, a farm town of about 3,500 in the Willamette Valley. The people who formulate, make and test them work under one roof, and the owners work in the building too. We're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much vitamin B12 is in each dot?\u003c\/h3\u003e\n\u003cp\u003eEach dot has 1,000 mcg of vitamin B12, which is 41,666% of the Daily Value. It comes from 500 mcg hydroxycobalamin, 400 mcg adenosylcobalamin and 100 mcg methylcobalamin.\u003c\/p\u003e\n\u003ch3\u003eIs 1,000 mcg of B12 too much?\u003c\/h3\u003e\n\u003cp\u003eNo upper limit has been set for vitamin B12; the Food and Nutrition Board didn't establish one because of B12's low potential for toxicity. If you take medication or have a medical condition, check with your healthcare practitioner first.\u003c\/p\u003e\n\u003ch3\u003eWhy are the dots cyanocobalamin-free?\u003c\/h3\u003e\n\u003cp\u003eBecause we chose the two forms your cells actually work with, plus hydroxycobalamin, which cells convert into both. Your body converts cyanocobalamin into the working forms too, so this is a formulation choice, not a knock on other forms.\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice anything?\u003c\/h3\u003e\n\u003cp\u003eThere's no set timeline, and you shouldn't expect a jolt, because B12 isn't a stimulant. It works as a helper in everyday cell reactions, so if your intake was already good you may not feel a difference at all. That's normal.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with B-12 Essential Trio or B-Complex?\u003c\/h3\u003e\n\u003cp\u003eYou can, but both already contain B12, so check the totals first. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/b12-sublingual-essential-trio\"\u003eB-12 Essential Trio liquid with folinate and B6\u003c\/a\u003e has 2,000 mcg of methylcobalamin per serving, and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/b-good-com-vitamin-b-complex\"\u003eour B-Complex with all eight B vitamins\u003c\/a\u003e has 100 mcg of vitamin B12 per capsule. If you want to combine them, ask your healthcare practitioner.\u003c\/p\u003e\n\u003ch3\u003eAre Triple B-12 Dots vegan?\u003c\/h3\u003e\n\u003cp\u003eThe label doesn't make a vegan claim. It does state \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives,\" and the other ingredients are listed in full above so you can decide for yourself.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/p5p-50mg-vitamin-b6-supplement\"\u003eP5P 50 mg, the coenzyme form of vitamin B6\u003c\/a\u003e, another B vitamin involved in homocysteine metabolism.†\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/everyday-liquid-sunshine-2-d3-k2\"\u003eEveryday Liquid Sunshine 2 vitamin D3 and K2 drops\u003c\/a\u003e, if you're building a simple daily foundation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eFroese DS et al. Vitamin B12, folate, and the methionine remethylation cycle-biochemistry, pathways, and regulation. J Inherit Metab Dis. 2019. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30693532\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKennedy DO. B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review. Nutrients. 2016. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26828517\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDoets EL et al. Systematic review on daily vitamin B12 losses and bioavailability for deriving recommendations on vitamin B12 intake with the factorial approach. Ann Nutr Metab. 2013. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23796635\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBor MV et al. Daily intake of 4 to 7 microg dietary vitamin B-12 is associated with steady concentrations of vitamin B-12-related biomarkers in a healthy young population. Am J Clin Nutr. 2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20071646\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eTucker KL et al. Plasma vitamin B-12 concentrations relate to intake source in the Framingham Offspring study. Am J Clin Nutr. 2000. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10648266\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBalk EM et al. Vitamin B6, B12, and folic acid supplementation and cognitive function: a systematic review of randomized trials. Arch Intern Med. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17210874\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364426019098,"sku":"015-A2200","price":19.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A2200_REV00_Necktag.png?v=1746812407"},{"product_id":"calming-magnesium-powder-relax","title":"Calming Mag Powder – Magnesium Drink for Relaxation and Restful Sleep | 300 g","description":"\u003cp\u003e\u003cstrong\u003eCalming Mag Powder is a berry-flavored magnesium drink mix with 400 mg of magnesium, 500 mg of glycine, 120 mg of vitamin C, 1,000 IU of vitamin D3, 15 mg of zinc, 98 mg of potassium and 3 mg of boron in every rounded scoop (about 5 grams). A 300 g tub holds 60 servings. Stirred into water at bedtime, it supports muscle relaxation and restful sleep.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCalming Mag Powder is for adults who want a simple wind-down habit: half a glass of water, one scoop, done before you brush your teeth. Magnesium is the main event. Your muscles and nerves use it every day, and national survey data summarized by the NIH show that about half of Americans get less magnesium from food than the average requirement for their age and sex.\u003c\/p\u003e\n\u003cp\u003eSleep and downtime are often the first things people in their 30s and 40s trade away. Aging isn't optional. Getting old is. A steady evening routine is an easy place to start adding life to your years.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Calming Mag Powder\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports normal muscle relaxation and nerve function with 400 mg of magnesium per scoop.†\u003c\/li\u003e\n\u003cli\u003eSupports restful sleep as part of a consistent bedtime routine.†\u003c\/li\u003e\n\u003cli\u003eSupports the body's normal response to occasional stress.†\u003c\/li\u003e\n\u003cli\u003ePairs 1,000 IU of vitamin D3 with the magnesium your body uses to activate it, for normal bone health.†\u003c\/li\u003e\n\u003cli\u003eAdds vitamin C and zinc, two nutrients that support normal immune function.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin C (ascorbic acid)\u003c\/td\u003e\n\u003ctd\u003e120 mg\u003c\/td\u003e\n\u003ctd\u003e200%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin D3 (cholecalciferol)\u003c\/td\u003e\n\u003ctd\u003e1,000 IU\u003c\/td\u003e\n\u003ctd\u003e250%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium (elemental)\u003c\/td\u003e\n\u003ctd\u003e400 mg\u003c\/td\u003e\n\u003ctd\u003e100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eZinc (elemental)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003e100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePotassium (elemental)\u003c\/td\u003e\n\u003ctd\u003e98 mg\u003c\/td\u003e\n\u003ctd\u003e2%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlycine\u003c\/td\u003e\n\u003ctd\u003e500 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBoron (elemental)\u003c\/td\u003e\n\u003ctd\u003e3 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: One (1) rounded scoop (approximately 5 grams). Servings per container: 60. Ingredients, as printed: Magnesium carbonate, citric acid, xylitol, glycine, natural berry and other natural flavors, potassium carbonate, ascorbic acid, boron citrate, zinc citrate, silica, and vitamin D3 (cholecalciferol). The label states: \"NO soy, salt, yeast, gluten, egg products, sugar, starch, or preservatives.\" The front label also carries Gluten-Free, Dairy-Free and Soy-Free icons.\u003c\/p\u003e\n\u003ch2\u003eHow Calming Mag Powder works\u003c\/h2\u003e\n\u003ch3\u003eMagnesium: 400 mg that dissolves as it fizzes\u003c\/h3\u003e\n\u003cp\u003eMagnesium is a mineral your body uses in more than 300 enzyme systems, including the ones behind muscle and nerve function, according to the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Magnesium-HealthProfessional\/\"\u003eNIH magnesium fact sheet\u003c\/a\u003e. It helps move calcium and potassium across cell membranes, which is part of how nerves fire and how muscles contract and then let go.†\u003c\/p\u003e\n\u003cp\u003eThe form is the interesting part. The tub holds magnesium carbonate and citric acid. Add water and they react: the fizz is carbon dioxide escaping as the carbonate meets the acid, and the minerals dissolve. The label puts it this way: \"The minerals are formed into citrate, glycinate, and ascorbate ionic forms naturally during the effervescent process.\"\u003c\/p\u003e\n\u003cp\u003eWhy does the citrate part matter? In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14596323\/\"\u003ea 60-day randomized, double-blind trial in 46 healthy adults\u003c\/a\u003e taking 300 mg of magnesium a day, citrate produced the highest blood magnesium levels of the forms tested, and magnesium oxide did no differently than placebo. Straight talk: one small study, a lower dose than ours, and it measured blood and urine levels, not how anyone slept.\u003c\/p\u003e\n\u003ch3\u003eWhat the sleep research shows, and what it doesn't\u003c\/h3\u003e\n\u003cp\u003eMagnesium and sleep is a promising, unfinished story. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35184264\/\"\u003eA systematic review of 9 studies covering 7,582 adults\u003c\/a\u003e found that observational studies link magnesium status with sleep quality and duration, while the randomized trials disagreed with each other.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40918053\/\"\u003ea placebo-controlled trial in 155 healthy adults who reported poor sleep\u003c\/a\u003e, 250 mg of magnesium a day (as bisglycinate) improved scores on a questionnaire about trouble falling and staying asleep by 3.9 points after 4 weeks, against 2.3 points on placebo. The researchers called the effect small. An exploratory analysis hinted that people who got less magnesium from food improved more, a lead the authors say needs more study.†\u003c\/p\u003e\n\u003ch3\u003eMagnesium and occasional stress\u003c\/h3\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33260549\/\"\u003eA review of magnesium and the stress response\u003c\/a\u003e describes magnesium as a brake in the body's normal stress signaling, and lays out a \"vicious circle\" idea: stress may increase the magnesium you lose, and running low may leave you more reactive to stress. It's a model built from lab and human studies, not a promise that one scoop makes a hard week easy.†\u003c\/p\u003e\n\u003ch3\u003eGlycine: 500 mg\u003c\/h3\u003e\n\u003cp\u003eGlycine is a non-essential amino acid, which means your body makes some on its own. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22529837\/\"\u003ea study of healthy volunteers whose sleep was cut by 25% for three nights\u003c\/a\u003e, 3 grams of glycine before bed reduced next-day fatigue and improved a reaction-time test compared with placebo. Notice the dose: 3 grams is six times the 500 mg in a scoop, so we won't claim this amount does the same.\u003c\/p\u003e\n\u003ch3\u003eVitamin D3: 1,000 IU\u003c\/h3\u003e\n\u003cp\u003eThis is D3 (cholecalciferol), the form your skin makes in sunlight; 1,000 IU equals 25 mcg. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29480918\/\"\u003eA review of magnesium's role in vitamin D activation\u003c\/a\u003e explains that the enzymes that process vitamin D in the liver and kidneys appear to need magnesium as a helper, and that activated vitamin D helps your body manage calcium and phosphate for normal bone maintenance.†\u003c\/p\u003e\n\u003ch3\u003eVitamin C, zinc, potassium and boron\u003c\/h3\u003e\n\u003cp\u003eVitamin C (120 mg, as ascorbic acid) and zinc (15 mg, from zinc citrate) both play a role in normal immune function, according to the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminC-HealthProfessional\/\"\u003eNIH vitamin C fact sheet\u003c\/a\u003e and the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Zinc-HealthProfessional\/\"\u003eNIH zinc fact sheet\u003c\/a\u003e.† Potassium is a small 98 mg, and boron (3 mg, from boron citrate) is a trace mineral with no established Daily Value. They round out the formula. The magnesium is the reason to buy it.\u003c\/p\u003e\n\u003ch2\u003eHow to take Calming Mag Powder\u003c\/h2\u003e\n\u003cp\u003eThe label's directions: \"One (1) rounded scoop (approximately 5 grams) in one half glass of water or juice for daily magnesium supplementation prior to retiring for sleep.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eExpect a fizz when the powder hits the water; that's the effervescent process the label describes. Let it settle before you drink.\u003c\/li\u003e\n\u003cli\u003eMagnesium from supplements can loosen stools. The NIH lists 350 mg a day as the adult upper limit for magnesium from supplements, and one scoop provides 400 mg, so if your digestion complains, ask your practitioner what amount suits you.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes, magnesium carbonate and glycine included.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e Or in a tub. More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Calming Mag Powder has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps formulators, makers and testers under one roof, and the owners work in the building too; the company has been owner-run since 2017. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much magnesium is in a scoop of Calming Mag Powder?\u003c\/h3\u003e\n\u003cp\u003eEach rounded scoop (about 5 grams) has 400 mg of elemental magnesium. Elemental means the magnesium itself, not the weight of the whole compound, so it's the number to compare. A 300 g tub holds 60 scoops, which is 60 nights at the label's serving.\u003c\/p\u003e\n\u003ch3\u003eWhen should I drink it?\u003c\/h3\u003e\n\u003cp\u003eAt bedtime. The label says to mix one rounded scoop into half a glass of water or juice \"prior to retiring for sleep.\" It doesn't say whether to take it with food.\u003c\/p\u003e\n\u003ch3\u003eHow soon will I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eIt varies, and some people won't feel much. In the 4-week trial above, the change was modest, and an exploratory analysis hinted at bigger improvements in people who got less magnesium from food. Give it a few weeks of nightly use, alongside a regular bedtime, before you judge it.†\u003c\/p\u003e\n\u003ch3\u003eDoes it have sugar in it?\u003c\/h3\u003e\n\u003cp\u003eNo. The label says no sugar. Its ingredient list includes xylitol, a sugar alcohol, and what the label calls \"natural berry and other natural flavors.\"\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Good Magnesium or Sleepy Sleep?\u003c\/h3\u003e\n\u003cp\u003eAdd up the magnesium first. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium\u003c\/a\u003e has 200 mg per capsule, so one capsule plus one scoop is 600 mg of supplemental magnesium a day, well past the 350 mg upper limit; ask your practitioner before doubling up. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/natural-sleep-aid-herbal-support\"\u003eSleepy Sleep\u003c\/a\u003e adds just 20 mg of magnesium per capsule, plus 1 mg of melatonin, 5-HTP and herbs, and its label says not to take it before driving or operating heavy equipment.\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner or pharmacist first. Magnesium can reduce how much of certain antibiotics and other prescription drugs you absorb, so the two may need to be taken hours apart.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/best-magnesium-supplements-for-sleep-2026\"\u003eHow magnesium forms and doses for sleep compare\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium, 200 mg of magnesium as a rice protein chelate per capsule\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/relaxation-supplement-passion-fl\"\u003eRelaxing Passion Flower, 50 mg of passionflower extract per lozenge\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/sleep-dots-melatonin-1mg\"\u003eSleep Dots, 1 mg melatonin you let dissolve\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eWalker AF et al. Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind study. Magnes Res. 2003. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14596323\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eArab A et al. The Role of Magnesium in Sleep Health: a Systematic Review of Available Literature. Biol Trace Elem Res. 2022. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35184264\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSchuster J et al. Magnesium Bisglycinate Supplementation in Healthy Adults Reporting Poor Sleep: A Randomized, Placebo-Controlled Trial. Nat Sci Sleep. 2025. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40918053\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003ePickering G et al. Magnesium Status and Stress: The Vicious Circle Concept Revisited. Nutrients. 2020. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33260549\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBannai M et al. The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Front Neurol. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22529837\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eUwitonze AM, Razzaque MS. Role of Magnesium in Vitamin D Activation and Function. J Am Osteopath Assoc. 2018. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29480918\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"300 g","offer_id":44364427133210,"sku":"015-A5008","price":47.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A5008_REV00_Necktag.png?v=1738588205"},{"product_id":"sleep-dots-melatonin-1mg","title":"Sleep Dots Melatonin 1 mg – Encourages Healthy Sleep | 60 Dissolvable Dots","description":"\u003cp\u003e\u003cstrong\u003eSleep Dots are a single-ingredient melatonin supplement: each dot holds 1 mg of pure crystalline melatonin and is made to dissolve in your mouth. The bottle holds 60 dots. Take one to six about half an hour before bedtime, per the label, to encourage healthy sleep and support your body's own sleep-wake cycle.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSleep Dots are for adults who want a little help falling asleep at bedtime on the nights sleep is slow to arrive, like after a late night or a weekend that pushed bedtime back.† The 1 mg dot is the whole idea: start small, and add more only if you need it.\u003c\/p\u003e\n\u003cp\u003eIf you're in your 30s or 40s, you're probably already working on the habits that decide how you'll feel at 70. Sleep sits underneath all of them. Aging isn't optional. Getting old is. A steady bedtime is one of the least glamorous ways to add life to your years, and a small dose of melatonin can help on the nights your schedule fights back.†\u003c\/p\u003e\n\u003ch2\u003eWhy people take Sleep Dots\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTo encourage healthy sleep, the job printed right on the label.†\u003c\/li\u003e\n\u003cli\u003eTo fall asleep more easily at bedtime, by adding to the \"it's night\" signal the body already sends.†\u003c\/li\u003e\n\u003cli\u003eTo support a healthy sleep-wake cycle, since melatonin is part of the system that keeps it on time.†\u003c\/li\u003e\n\u003cli\u003eTo start low: at 1 mg per dot, you can find the smallest amount that works for you within the label's one to six dots.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePure Crystalline Melatonin\u003c\/td\u003e\n\u003ctd\u003e1 mg\u003c\/td\u003e\n\u003ctd\u003e* (Daily Value Not Established)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eServing size:\u003c\/strong\u003e 1 Dot. \u003cstrong\u003eServings per container:\u003c\/strong\u003e not printed on the Supplement Facts panel; the bottle holds 60 dots. \u003cstrong\u003eOther ingredients:\u003c\/strong\u003e Lactose, Enhance™, acacia, cellulose, and magnesium stearate. \u003cstrong\u003eLabel statements:\u003c\/strong\u003e \"NO soy, salt, yeast, gluten, egg, sugar, starch, or preservatives.\" \"Formulated with Enhance™ metabolite uptake enhancers. Contains citrus products.\" \"Contains lactose, from milk.\"\u003c\/p\u003e\n\u003ch2\u003eHow Sleep Dots work\u003c\/h2\u003e\n\u003ch3\u003eMelatonin is your body's \"it's night\" signal\u003c\/h3\u003e\n\u003cp\u003eMelatonin is a hormone your body makes on its own. Levels rise at night, and bright light shuts that down: in a 1980 study, bright artificial light at night suppressed melatonin release in six healthy volunteers, while dimmer room light did not (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7434030\/\"\u003eLewy 1980\u003c\/a\u003e). So melatonin works as a timing signal. It tells the rest of your body what time it is.†\u003c\/p\u003e\n\u003cp\u003eThat signal shows up in body temperature. In a double-blind, placebo-controlled study of 20 healthy men, daytime doses from 0.1 to 10 mg lowered oral temperature, raised self-reported sleepiness, and shortened the time it took them to drift off in a simple sleep test (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8127888\/\"\u003eDollins 1994\u003c\/a\u003e).†\u003c\/p\u003e\n\u003ch3\u003eWhy 1 mg per dot\u003c\/h3\u003e\n\u003cp\u003eMore melatonin isn't automatically more useful. In that same study, blood levels rose in step with the dose, and the 0.1 mg and 0.3 mg doses produced peaks inside the normal nighttime range (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8127888\/\"\u003eDollins 1994\u003c\/a\u003e). A second sleep-lab study gave 12 healthy young volunteers 0.3 mg, 1 mg or a placebo at 9 PM, two to four hours before their usual bedtime. Both doses shortened the time it took to fall asleep, neither changed the overall structure of their sleep, and neither left people worse off on next-morning mood or performance tests (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e).†\u003c\/p\u003e\n\u003cp\u003eThat's the case for a 1 mg dot: a small dose in the range those studies used, so you can stay at one if it does the job.\u003c\/p\u003e\n\u003ch3\u003eWhat the research does and doesn't show\u003c\/h3\u003e\n\u003cp\u003eThe low-dose studies are small sleep-lab trials, mostly in healthy young men. They measured how quickly people fell asleep, not how rested they felt weeks later, and none tested dissolvable dots or half-hour timing. The honest summary: the research supports falling asleep a bit more easily, not a dramatic change.†\u003c\/p\u003e\n\u003ch3\u003eWhy a dot that dissolves in your mouth\u003c\/h3\u003e\n\u003cp\u003eThe label directs you to let the dots dissolve in your mouth. For context, a systematic review of 22 studies found that oral, immediate-release melatonin peaked in the blood about 50 minutes after a dose, had a half-life of about 45 minutes, and only about 15% reached the bloodstream (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26008214\/\"\u003eHarpsøe 2015\u003c\/a\u003e). Those numbers come from other oral forms, and we haven't found good published data comparing dissolvable dots with tablets, so we don't claim the dots work faster. The short half-life does mean melatonin doesn't linger, which suits a bedtime dose.†\u003c\/p\u003e\n\u003ch3\u003eWhat else is in the dot\u003c\/h3\u003e\n\u003cp\u003eLactose (milk sugar) is the first of the other ingredients listed, hence \"Contains lactose, from milk.\" Acacia is a plant gum, cellulose is a plant fiber, and magnesium stearate is a common manufacturing aid. The label describes Enhance™ as \"metabolite uptake enhancers\" and notes that the dots contain citrus products; we quote the label and make no further claim about it.\u003c\/p\u003e\n\u003ch3\u003eWhy the number on the label matters\u003c\/h3\u003e\n\u003cp\u003eWith melatonin, the label and the bottle don't always agree. In a 2017 lab analysis of 31 melatonin supplements, measured melatonin ranged from 83% below to 478% above the label amount, and one product varied by as much as 465% from lot to lot (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27855744\/\"\u003eErland 2017\u003c\/a\u003e). When the point is a small, precise dose, that's worth checking, and every lot of Sleep Dots has a certificate of analysis.\u003c\/p\u003e\n\u003ch2\u003eHow to take Sleep Dots\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDirections (from the label):\u003c\/strong\u003e \"As a dietary supplement, allow one to six dots dissolve in mouth 1\/2 hour before bedtime. Best if taken on an empty stomach.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStart with one dot.\u003c\/strong\u003e If that isn't enough, add one at a time on later nights, staying within the label's six.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep it for bedtime.\u003c\/strong\u003e In the 1994 study, melatonin made people sleepier and less accurate on an alertness task (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8127888\/\"\u003eDollins 1994\u003c\/a\u003e), so take it only when you're done driving for the night.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkip bright light before bed.\u003c\/strong\u003e Bright light at night shuts down your own melatonin release (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7434030\/\"\u003eLewy 1980\u003c\/a\u003e), so keeping bright lights off near bedtime lets your own signal do its job too.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWarning (from the label):\u003c\/strong\u003e \"Not recommended while pregnant or lactating unless directed by health care practitioner. Individuals under 18 years old consult with health care practitioner before use.\" The label also states \"Contains lactose, from milk.\" Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test. We test every incoming ingredient lot, the melatonin included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\/wake-sleep-dots-120-dots\"\u003eSee the certificates of analysis for this product\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 in the Willamette Valley, and our UL-certified cGMP facility is right in it. The people who formulate, make and test Sleep Dots work under one roof, and the owners work in the building too; the company has been owner-run since 2017. We've been making supplements in Oregon since 1974. Fifty-two years in, we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many Sleep Dots should I take?\u003c\/h3\u003e\n\u003cp\u003eThe label says one to six dots, 1\/2 hour before bedtime, which is 1 to 6 mg of melatonin. A sensible start is one dot, adding more on later nights only if needed, since the sleep-lab studies saw an effect at 1 mg and below (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e).†\u003c\/p\u003e\n\u003ch3\u003eWhen should I take Sleep Dots, and with or without food?\u003c\/h3\u003e\n\u003cp\u003eAbout half an hour before bedtime, on an empty stomach, per the label. Eating is one of the factors a systematic review found can change how the body handles melatonin (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26008214\/\"\u003eHarpsøe 2015\u003c\/a\u003e).\u003c\/p\u003e\n\u003ch3\u003eHow soon will I notice a difference?\u003c\/h3\u003e\n\u003cp\u003ePossibly the first night. In the sleep-lab studies, a single evening dose shortened the time healthy volunteers took to fall asleep that same night (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e). Expect to fall asleep a bit more easily, not a dramatic change.†\u003c\/p\u003e\n\u003ch3\u003eWill Sleep Dots make me groggy the next morning?\u003c\/h3\u003e\n\u003cp\u003eNot at the doses tested in the 1996 study: neither 0.3 mg nor 1 mg left people worse off on next-morning mood or performance tests (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e).† A 2016 review of the safety research reported only mild side effects, such as dizziness, headache, nausea and sleepiness (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26692007\/\"\u003eAndersen 2016\u003c\/a\u003e).\u003c\/p\u003e\n\u003ch3\u003eCan I take Sleep Dots with Sleepy Sleep or Melatonin 3 mg Timed Release?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, since both contain melatonin too. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/natural-sleep-aid-herbal-support\"\u003eSleepy Sleep\u003c\/a\u003e has 1 mg per capsule alongside herbs and 5-HTP, and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/melatonin-3mg-timed-release\"\u003eMelatonin 3 mg Timed Release\u003c\/a\u003e has 3 mg per capsule; its label says it releases about 1.5 mg in the first hour and the rest over the next five hours. No label gives directions for combining them, so the simple approach is to pick one.\u003c\/p\u003e\n\u003ch3\u003eAre Sleep Dots safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner before you start. Some medications change how the body handles melatonin, including oral contraceptives and fluvoxamine, and so do caffeine and smoking (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26008214\/\"\u003eHarpsøe 2015\u003c\/a\u003e).\u003c\/p\u003e\n\u003ch3\u003eDo Sleep Dots contain dairy or gluten?\u003c\/h3\u003e\n\u003cp\u003eThey contain lactose, from milk; the label says so directly. The label also says \"NO soy, salt, yeast, gluten, egg, sugar, starch, or preservatives\" and \"Contains citrus products.\" If you avoid milk or citrus, Sleep Dots aren't a fit.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium\u003c\/a\u003e: 200 mg of magnesium as a rice protein chelate in each capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calming-magnesium-powder-relax\"\u003eCalming Mag Powder\u003c\/a\u003e: 400 mg of magnesium and 500 mg of glycine per scoop, stirred into water before bed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eLewy AJ et al. Light suppresses melatonin secretion in humans. Science. 1980. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7434030\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDollins AB et al. Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proc Natl Acad Sci U S A. 1994. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8127888\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eZhdanova IV et al. Effects of low oral doses of melatonin, given 2-4 hours before habitual bedtime, on sleep in normal young humans. Sleep. 1996. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHarpsøe NG et al. Clinical pharmacokinetics of melatonin: a systematic review. Eur J Clin Pharmacol. 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26008214\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eErland LA, Saxena PK. Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin Content. J Clin Sleep Med. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27855744\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAndersen LP et al. The Safety of Melatonin in Humans. Clin Drug Investig. 2016. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26692007\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364425527578,"sku":"015-A7007","price":15.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A7007_REV00_Necktag.png?v=1747248651"},{"product_id":"b12-sublingual-essential-trio","title":"B-12 Essential Trio – B12, Folinate \u0026 B6 for Energy Metabolism | 2 fl oz Liquid","description":"\u003cp\u003e\u003cstrong\u003eB-12 Essential Trio is a blueberry-flavored liquid with three B vitamins. One serving (a single dropper bulb squeeze, about 0.84 grams) gives 2,000 mcg of vitamin B12 as methylcobalamin, 680 mcg DFE of folate as folinate and 4 mg of vitamin B6. Each 2 fl oz bottle holds 80 servings. Together, these vitamins support normal energy metabolism and healthy homocysteine metabolism.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eB12 occurs naturally only in animal foods, so anyone eating little or no meat, fish, eggs or dairy may need another source. The NIH also advises people over 50 to get most of their B12 from fortified foods or supplements, since many older adults don't make enough stomach acid to free B12 from food (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB12-Consumer\/\"\u003ethe NIH's consumer guide to vitamin B12\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eIf you're in your 30s or 40s and building habits so you can keep up at 75, half a dropper each morning is about as easy as a habit gets. No pills to swallow. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003ch2\u003eWhy people take B-12 Essential Trio\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports normal energy metabolism, because B12 and B6 are coenzymes your cells use to turn parts of protein and fat into fuel.†\u003c\/li\u003e\n\u003cli\u003eSupports healthy homocysteine levels already within the normal range, as B12 and folate recycle homocysteine into methionine.†\u003c\/li\u003e\n\u003cli\u003eSupports normal red blood cell formation and DNA synthesis, with folate and B12 working together.†\u003c\/li\u003e\n\u003cli\u003eSupports healthy nervous system function.†\u003c\/li\u003e\n\u003cli\u003eHelps people who eat few animal foods, and adults over 50, keep B12 intake up.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B6 (from Pyridoxine HCl)\u003c\/td\u003e\n\u003ctd\u003e4 mg\u003c\/td\u003e\n\u003ctd\u003e235%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFolinate (from Calcium Folinate)\u003c\/td\u003e\n\u003ctd\u003e680 mcg DFE\u003c\/td\u003e\n\u003ctd\u003e170%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B12 (Methylcobalamin)\u003c\/td\u003e\n\u003ctd\u003e2,000 mcg\u003c\/td\u003e\n\u003ctd\u003e83,333%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 1 Dropper Bulb Squeeze (Approximately half a dropper full, Approximately 0.84 grams). Servings per container: 80. Other ingredients: Vegetable Glycerin, Purified Water, Citric Acid, Potassium Sorbate, and Natural Blueberry Flavor. The label states: \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or artificial colors or flavors.\" It also says: \"Refrigerate after opening.\" Potassium sorbate is a preservative.\u003c\/p\u003e\n\u003ch2\u003eHow B-12 Essential Trio works\u003c\/h2\u003e\n\u003ch3\u003eMethylcobalamin (2,000 mcg): B12 for the methylation cycle\u003c\/h3\u003e\n\u003cp\u003eB12 is a coenzyme, a helper molecule two enzymes can't work without, and methylcobalamin is one of the two forms your cells use in that role (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB12-HealthProfessional\/\"\u003eNIH fact sheet on vitamin B12\u003c\/a\u003e). It partners with methionine synthase, the enzyme that recycles homocysteine into methionine, which your body turns into SAMe, its most important methyl donor. That same step pulls a one-carbon unit off folate so folate can keep cycling into DNA building blocks, which is why B12 and folate come as a pair. B12's other coenzyme form helps your mitochondria turn leftovers from breaking down certain amino acids into fuel (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30693532\/\"\u003eFroese et al., 2019\u003c\/a\u003e).†\u003c\/p\u003e\n\u003cp\u003eStraight talk: your cells process any B12 they absorb before using it, and the NIH says there's no evidence that absorption differs by form. We chose methylcobalamin because it's one of the two coenzyme forms, not because we can show it's absorbed or used better.\u003c\/p\u003e\n\u003ch3\u003eWhy 2,000 mcg when the Daily Value is 2.4 mcg\u003c\/h3\u003e\n\u003cp\u003eBecause the share you absorb drops as the dose rises: the NIH puts absorption near 50% for doses under 1 to 2 mcg but about 1.3% of a 1,000 mcg dose. A systematic review saw the same pattern with food: people absorbed 83% of a 3 mcg dose but only 4.5% of a 38 mcg dose (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23796635\/\"\u003eDoets et al., 2013\u003c\/a\u003e). A big dose offsets a small percentage.\u003c\/p\u003e\n\u003ch3\u003eFolinate (680 mcg DFE): folate that skips a slow step\u003c\/h3\u003e\n\u003cp\u003eFolate carries the one-carbon units your cells need to build DNA and keep the methionine cycle turning.† Most supplements use folic acid, a fully oxidized form your body must first convert with an enzyme called DHFR; food folates are already in the reduced tetrahydrofolate form (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Folate-HealthProfessional\/\"\u003eNIH fact sheet on folate\u003c\/a\u003e). In liver tissue from six people, DHFR converted folic acid at less than 2% of the rate seen in rat liver, and activity varied almost fivefold between people (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19706381\/\"\u003eBailey and Ayling, 2009\u003c\/a\u003e). Folinate is a formyl form of tetrahydrofolate, the same reduced family as food folate, so it doesn't wait on DHFR. To be fair, that was a lab study, not a supplement trial, and the NIH puts folic acid absorption at about 85% with food. Folinate just takes one step out of the way.\u003c\/p\u003e\n\u003ch3\u003eVitamin B6 (4 mg from pyridoxine HCl): the protein-metabolism helper\u003c\/h3\u003e\n\u003cp\u003eYour body turns pyridoxine into pyridoxal 5' phosphate (PLP), the coenzyme form of B6, which takes part in more than 100 enzyme reactions, mostly in protein metabolism (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB6-HealthProfessional\/\"\u003eNIH fact sheet on vitamin B6\u003c\/a\u003e).† One review names B6, B12 and folate as the B vitamins most involved in homocysteine metabolism, and describes the B group's roles in energy production, DNA synthesis and making the brain's chemical messengers (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26828517\/\"\u003eKennedy, 2016\u003c\/a\u003e).† Pyridoxine HCl is the most common B6 form in supplements; if you want B6 already in coenzyme form, that's \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/p5p-50mg-vitamin-b6-supplement\"\u003eour P5P 50 mg\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eWhat the research does and doesn't show\u003c\/h3\u003e\n\u003cp\u003eWhat it shows: a pooled analysis of 25 randomized trials with 2,596 participants found folic acid reduced blood homocysteine by 13% to 25%, depending on dose; B12 (0.4 mg a day) brought it down about 7% more, and B6 had no significant effect (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16210710\/\"\u003eHomocysteine Lowering Trialists' Collaboration, 2005\u003c\/a\u003e). Those trials used folic acid, not folinate, and none tested this product.\u003c\/p\u003e\n\u003cp\u003eWhat it doesn't show: that B vitamins sharpen your thinking. A systematic review of 14 randomized trials found no clear effect of B6, B12 or folic acid on cognitive test scores, and most trials were small or low quality (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17210874\/\"\u003eBalk et al., 2007\u003c\/a\u003e). We haven't run a trial on B-12 Essential Trio itself; what we can show you is what's in each serving and how every lot is tested.\u003c\/p\u003e\n\u003ch2\u003eHow to take B-12 Essential Trio\u003c\/h2\u003e\n\u003cp\u003eThe label directions, word for word: \"Take one serving by mouth in the morning.\" One serving is a single squeeze of the dropper bulb, which fills about half the dropper.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSqueeze the bulb once, release, and drip the liquid into your mouth, or into a little water or juice.\u003c\/li\u003e\n\u003cli\u003eRefrigerate after opening, as the label says.\u003c\/li\u003e\n\u003cli\u003eAt one serving each morning, a bottle's 80 servings last 80 days.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. The label gives no serving for children, so check with your child's practitioner first. Acid-reducing medicines can make it harder to absorb B12 from food.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cp\u003eWe've been making supplements in Oregon since 1974. Fifty-two years in, here's how we back up this label:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, the methylcobalamin, folinate and B6 included, for identity, potency, heavy metals and microbes. Here's \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/our-approach-to-raw-material-sourcing-and-testing\"\u003ehow we source and test raw materials\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\/b12-sublingual-essential-trio\"\u003eSee the certificates of analysis for this product\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e B-12 Essential Trio is made in our UL-certified cGMP facility in Mt. Angel, a farm town of about 3,500 in the Willamette Valley. The people who formulate, make and test it work under one roof, and the owners work in the building too. We're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much B12, folate and B6 is in one serving?\u003c\/h3\u003e\n\u003cp\u003eOne serving has 2,000 mcg of vitamin B12 as methylcobalamin (83,333% of the Daily Value), 680 mcg DFE of folate as folinate (170%) and 4 mg of vitamin B6 from pyridoxine HCl (235%).\u003c\/p\u003e\n\u003ch3\u003eIs B-12 Essential Trio a sublingual B12?\u003c\/h3\u003e\n\u003cp\u003eYou can take it that way; the label simply says to take one serving by mouth in the morning. Holding it under your tongue first is fine, though the NIH says evidence suggests no difference in efficacy between oral and sublingual B12.\u003c\/p\u003e\n\u003ch3\u003eIs 2,000 mcg of B12 too much?\u003c\/h3\u003e\n\u003cp\u003eIt's a large dose, but no upper limit has been set for vitamin B12 because of its low potential for toxicity, and you absorb only a small share of it. The 4 mg of B6 is well under the 100 mg adult upper limit. If you take medication, check with your practitioner first.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with B-Complex or Triple B-12 Dots?\u003c\/h3\u003e\n\u003cp\u003eCheck the totals first, because they overlap. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/b-good-com-vitamin-b-complex\"\u003eOur B-Complex with all eight B vitamins\u003c\/a\u003e already has 100 mg of B6 per capsule, so adding B-12 Essential Trio brings B6 to 104 mg a day, just over the 100 mg adult upper limit. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/b12-dots-energy-nervous-support\"\u003eTriple B-12 Dots\u003c\/a\u003e add 1,000 mcg of B12 per dot, which you likely don't need on top of 2,000 mcg. Most people pick one, or ask a practitioner first.\u003c\/p\u003e\n\u003ch3\u003eHow soon will I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eThere's no jolt, because B vitamins aren't stimulants; they keep enzymes supplied. If your intake was already good, you may not feel a difference at all, and that's normal.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eFroese DS et al. Vitamin B12, folate, and the methionine remethylation cycle-biochemistry, pathways, and regulation. J Inherit Metab Dis. 2019. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30693532\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDoets EL et al. Systematic review on daily vitamin B12 losses and bioavailability for deriving recommendations on vitamin B12 intake with the factorial approach. Ann Nutr Metab. 2013. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23796635\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBailey SW et al. The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake. Proc Natl Acad Sci U S A. 2009. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19706381\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKennedy DO. B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review. Nutrients. 2016. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26828517\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHomocysteine Lowering Trialists' Collaboration. Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials. Am J Clin Nutr. 2005. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16210710\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBalk EM et al. Vitamin B6, B12, and folic acid supplementation and cognitive function: a systematic review of randomized trials. Arch Intern Med. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17210874\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"1","offer_id":44364424479002,"sku":"015-M2210","price":25.99,"currency_code":"USD","in_stock":true},{"title":"3","offer_id":44900315201818,"sku":"015-M2210-3","price":69.99,"currency_code":"USD","in_stock":true},{"title":"5","offer_id":44900315234586,"sku":"015-M2210-5","price":109.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M2210_REV02_Box.png?v=1738258018"},{"product_id":"relaxation-supplement-passion-fl","title":"Relaxing Passion Flower 50 mg – Promotes Relaxation | 60 Vegetarian Lozenges","description":"\u003cp\u003e\u003cstrong\u003eRelaxing Passion Flower is a single-ingredient herbal lozenge. Each vegetarian lozenge delivers 50 mg of Passion Flower 4:1 Extract (Passiflora incarnata), and each bottle holds 60. You let it dissolve in your mouth; the label says one or more lozenges throughout the day. Passionflower is traditionally used to promote relaxation, so you can take the edge off a busy day and wind down at night.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis is for the person whose day doesn't come with an off switch: work, kids, parents, a phone that never stops buzzing. You want something small you can keep in a bag or a desk drawer, take without water, and reach for when the day gets loud.\u003c\/p\u003e\n\u003cp\u003eAging isn't optional. Getting old is. A wind-down routine you start in your 30s and 40s is one you can still be using in your 70s, so build one you'll actually keep. A lozenge, a few slow breaths and the phone in another room is a decent start.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Relaxing Passion Flower\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTo promote relaxation, the one job printed on the label.†\u003c\/li\u003e\n\u003cli\u003eTo take the edge off occasional, everyday stress.†\u003c\/li\u003e\n\u003cli\u003eTo support a calm, settled mood through a packed day.†\u003c\/li\u003e\n\u003cli\u003eTo help them wind down in the evening and support restful sleep.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePassion Flower 4:1 Extract (Passiflora incarnata)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003e* (Daily Value Not Established)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 1 Vegetarian Lozenge. With 60 lozenges in the bottle and a one-lozenge serving, that's 60 servings. Other ingredients: Xylitol, organic evaporated cane juice, cellulose, palm kernel stearate, citric acid, natural flavor, and silica. The label states: \"NO alcohol, soy, salt, yeast, gluten, milk \u0026amp; egg products, starch, or preservatives.\" It also states: \"One lozenge is 2 times the strength of one dropperful (35 drops) of liquid passion flower alcohol extract.\"\u003c\/p\u003e\n\u003ch2\u003eHow Relaxing Passion Flower works\u003c\/h2\u003e\n\u003ch3\u003ePassionflower, the plant\u003c\/h3\u003e\n\u003cp\u003ePassiflora incarnata is a climbing vine. People have used it for a long time, and in North America it has a history as a calming tea (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24140586\/\"\u003ea 2013 review of passionflower's traditional use and clinical research\u003c\/a\u003e). Relaxing Passion Flower keeps it simple: one herb, one amount, nothing else doing the work.\u003c\/p\u003e\n\u003ch3\u003eWhat \"4:1 extract\" means\u003c\/h3\u003e\n\u003cp\u003eA 4:1 extract means roughly 4 parts of starting plant material go into every 1 part of finished extract. So the 50 mg in each lozenge is a concentrate, not 50 mg of ground-up plant. The label identifies the extract by that ratio. It doesn't claim standardization to a specific marker compound, so we won't either.\u003c\/p\u003e\n\u003ch3\u003eThe GABA connection\u003c\/h3\u003e\n\u003cp\u003eYour nervous system runs on a balance of \"go\" and \"ease off\" signals. GABA (gamma-aminobutyric acid) is the main \"ease off\" messenger. In a lab study using rat brain tissue, a passionflower dry extract showed affinity for both main types of GABA receptors (GABA-A and GABA-B) and reduced GABA uptake into nerve endings, and the authors concluded that passionflower acts partly through the GABA system (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21089181\/\"\u003ea lab study of passionflower and the GABA system\u003c\/a\u003e). That's test-tube work, and the picture isn't one-directional (the extract blocked GABA-B receptors in one test). It suggests a way passionflower may help you relax, but it can't tell us what one lozenge does inside a person.†\u003c\/p\u003e\n\u003ch3\u003eWhat the human research shows, and what it doesn't\u003c\/h3\u003e\n\u003cp\u003eThe clearest study in healthy people is small. In a double-blind, placebo-controlled crossover trial, 41 healthy adults aged 18 to 35 drank a cup of passionflower tea or a placebo tea daily for a week each and kept a sleep diary. Of six sleep-diary measures, sleep quality was the one rated significantly higher with passionflower (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21294203\/\"\u003ea crossover study of passionflower tea in 41 healthy adults\u003c\/a\u003e).† The authors called the benefit short-term and subjective, in healthy adults with mild ups and downs in sleep quality. Encouraging, not conclusive: it was tea, not a lozenge, and it lasted one week.\u003c\/p\u003e\n\u003cp\u003eThe 2013 review above found that many passionflower trials were small, described their extracts poorly, or skipped details on blinding and randomization, and its authors called for better-designed studies. The same review described the plant's safety profile as good. We'd rather tell you that up front than oversell a 50 mg lozenge.\u003c\/p\u003e\n\u003ch3\u003eWhy a lozenge\u003c\/h3\u003e\n\u003cp\u003eA lozenge dissolves slowly in your mouth. No water, no capsule to swallow, and no alcohol in the lozenge itself. We haven't seen research showing a lozenge absorbs differently than a capsule, so the lozenge is about convenience, not absorption.\u003c\/p\u003e\n\u003cp\u003eThe rest of the lozenge is there to make it a lozenge. Xylitol and organic evaporated cane juice sweeten it. Cellulose binds it, palm kernel stearate and silica keep the blend from sticking and clumping during production, and citric acid and natural flavor handle the taste. Organic evaporated cane juice is a form of cane sugar, so this lozenge isn't sugar-free.\u003c\/p\u003e\n\u003ch3\u003eWhy we test the extract itself\u003c\/h3\u003e\n\u003cp\u003eHerbal extracts are easy to get wrong. When German researchers analyzed a set of passionflower products, five of the six food supplements they tested failed identity or content checks, while all five registered herbal medicinal products passed. Their advice to manufacturers: test every batch (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40245939\/\"\u003ea 2025 quality analysis of passionflower products\u003c\/a\u003e). That's a small sample, not a verdict on any particular company. It is exactly why we test every incoming ingredient lot before it's used.\u003c\/p\u003e\n\u003ch2\u003eHow to take Relaxing Passion Flower\u003c\/h2\u003e\n\u003cp\u003eThe label directions: \"Take one or more lozenges throughout the day, as a dietary supplement.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLet the lozenge dissolve slowly in your mouth instead of chewing it or swallowing it whole.\u003c\/li\u003e\n\u003cli\u003eStart with one and see how you feel. The label doesn't set a daily maximum, so if you find yourself wanting several a day, check in with your practitioner.\u003c\/li\u003e\n\u003cli\u003ePassionflower is taken to help you relax, so see how it affects you before you drive or do anything that needs your full attention.\u003c\/li\u003e\n\u003cli\u003eEach lozenge contains xylitol, which is dangerous for dogs. Keep the bottle where pets can't get to it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, passionflower extract included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Relaxing Passion Flower gets its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e That's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility is where the formulators, the makers and the testers all work under one roof. The owners work in the building too, and the company has been owner-run since 2017. We've been making supplements in Oregon since 1974. And we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many Relaxing Passion Flower lozenges can I take a day?\u003c\/h3\u003e\n\u003cp\u003eThe label says to take one or more lozenges throughout the day, and it doesn't set a daily maximum. Start with one, see how you feel, and talk with your practitioner if you find you want several a day.\u003c\/p\u003e\n\u003ch3\u003eWhen should I take it, and do I need food or water?\u003c\/h3\u003e\n\u003cp\u003eTake it whenever you want to wind down. The label doesn't mention food, and because it dissolves in your mouth, you don't need water. The label says throughout the day, so that can be a midafternoon lozenge before a tough meeting or one after dinner as your evening slows down.†\u003c\/p\u003e\n\u003ch3\u003eHow long does it take to notice anything?\u003c\/h3\u003e\n\u003cp\u003eWe can't give you a number; there's no timing data on this lozenge. In the small tea study above, people drank the tea daily for a week before their sleep ratings were compared, and that's the only timeline the research gives us.†\u003c\/p\u003e\n\u003ch3\u003eIs Relaxing Passion Flower sugar-free?\u003c\/h3\u003e\n\u003cp\u003eNo. It's sweetened with xylitol and organic evaporated cane juice, which is a form of cane sugar.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Sleepy Sleep?\u003c\/h3\u003e\n\u003cp\u003eYes, and we sell them together in the \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calm-sleep-stack-sleepy-passion-ht\"\u003eCalm + Sleep Stack with Sleepy Sleep, Relaxing Passion Flower and 5-HTP\u003c\/a\u003e. Know that Sleepy Sleep also contains 50 mg of Passionflower Herb 4:1 Extract per capsule, plus melatonin and 5-HTP. Its label calls for one to two capsules 45 to 60 minutes before sleep, warns against taking it before driving, says it isn't recommended while pregnant or nursing unless a practitioner directs it, and asks anyone under 18 to check with a practitioner first. A simple split: a lozenge during the day when you want one, Sleepy Sleep at bedtime.\u003c\/p\u003e\n\u003ch3\u003eHow is a lozenge different from passionflower capsules or tinctures?\u003c\/h3\u003e\n\u003cp\u003eMostly it's convenience: it dissolves in your mouth, needs no water and contains no alcohol. The label says one lozenge is 2 times the strength of one dropperful (35 drops) of liquid passion flower alcohol extract. We don't claim it absorbs differently than a capsule.\u003c\/p\u003e\n\u003ch3\u003eIs it safe with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first. Passionflower is taken to help you relax, so it could add to the effects of other things that make you drowsy, including some prescriptions and alcohol. Check with them too if you're pregnant or nursing.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/natural-sleep-aid-herbal-support\"\u003eSleepy Sleep, our bedtime formula with chamomile, hops, passionflower and 1 mg melatonin per capsule\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calm-sleep-stack-sleepy-passion-ht\"\u003eThe Calm + Sleep Stack, all three bottles in one order\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calming-magnesium-powder-relax\"\u003eCalming Mag Powder, a magnesium drink for your bedtime routine\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eMiroddi M et al. Passiflora incarnata L.: ethnopharmacology, clinical application, safety and evaluation of clinical trials. J Ethnopharmacol. 2013. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24140586\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAppel K et al. Modulation of the γ-aminobutyric acid (GABA) system by Passiflora incarnata L. Phytother Res. 2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21089181\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eNgan A et al. A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality. Phytother Res. 2011. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21294203\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBrouns A et al. Passionflower (Passiflora incarnata): Quality of Food Supplements Versus Registered Herbal Medicinal Products. Planta Med. 2025. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40245939\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424347930,"sku":"015-M1024","price":21.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1024_REV03_Necktag.png?v=1738590323"},{"product_id":"everyday-liquid-sunshine-bone-imm","title":"Everyday Liquid Sunshine D3 1,000 IU – Bone \u0026 Immune Support | 1 fl oz Drops","description":"\u003cp\u003e\u003cstrong\u003eEveryday Liquid Sunshine is a liquid vitamin D3 supplement. Each drop delivers 25 mcg (1,000 IU) of vitamin D3 as cholecalciferol, 125% of the Daily Value, dissolved in fractionated coconut oil with natural lemon flavor. One 1 fl oz bottle holds 1,400 one-drop servings. Vitamin D helps your body absorb calcium and supports healthy bones, normal muscle function and normal immune function.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eYour skin makes vitamin D from UVB light, which works fine until you spend daylight hours indoors (UVB doesn't get through window glass) or live somewhere with a long gray winter. Hello, Oregon. Everyday Liquid Sunshine is for adults who want a steady 1,000 IU a day in one drop, with no pill to swallow, for less than 2 cents a serving.\u003c\/p\u003e\n\u003cp\u003eIf you're in your late 30s or 40s, this is a good time to start. The habits you build now carry you into your 70s and 80s, and bones are a long game. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Everyday Liquid Sunshine\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBones.\u003c\/strong\u003e Vitamin D helps your gut absorb calcium, the main building block of bone, and supports healthy bones.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMuscles.\u003c\/strong\u003e Your muscles need vitamin D to move, and it supports normal muscle function.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune function.\u003c\/strong\u003e Your immune cells carry vitamin D receptors, and vitamin D supports normal immune function.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHealthy vitamin D levels.\u003c\/strong\u003e D3 is the form your skin makes, and in a daily-dose trial it raised blood vitamin D more than the same amount of D2.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin D3 (cholecalciferol)\u003c\/td\u003e\n\u003ctd\u003e25 mcg\u003c\/td\u003e\n\u003ctd\u003e125%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size is 1 drop, and the label lists 1,400 servings per container. Other ingredients, as printed: Fractionated coconut oil and natural lemon flavor. The label also states: \"NO corn, soy, salt, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" The label doesn't name the source of the vitamin D3, so we don't describe this product as vegan.\u003c\/p\u003e\n\u003ch2\u003eHow Everyday Liquid Sunshine works\u003c\/h2\u003e\n\u003ch3\u003eVitamin D3: the form your skin makes\u003c\/h3\u003e\n\u003cp\u003eVitamin D3 (cholecalciferol) is the form your skin produces from sunlight, and it isn't active yet when you take it. Your liver turns it into 25-hydroxyvitamin D, the form a blood test measures, and your kidneys turn that into calcitriol, the active form that helps your gut absorb calcium (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminD-HealthProfessional\/\"\u003ethe NIH fact sheet on how vitamin D is activated and how much adults need\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eWhy D3 and not D2? In a 12-week randomized, placebo-controlled trial, 335 healthy women aged 20 to 64 took 15 mcg a day of D2 or D3 in juice or a biscuit through a UK winter. Blood vitamin D in the D3 groups rose about 15 to 17 nmol\/L more than in the D2 groups (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28679555\/\"\u003ea daily-dose trial comparing D2 and D3\u003c\/a\u003e). One trial, women only, a lower dose than one drop: read it as direction, not a number to expect.\u003c\/p\u003e\n\u003ch3\u003eWhat one drop a day does to your levels\u003c\/h3\u003e\n\u003cp\u003eIn a winter study of 67 healthy men given 0, 25, 125 or 250 mcg of D3 a day for about 20 weeks, blood 25-hydroxyvitamin D changed in direct proportion to the dose, about 0.7 nmol\/L for every extra microgram a day (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12499343\/\"\u003ea dose-response study of daily vitamin D3\u003c\/a\u003e). At that rate, a 25 mcg drop works out to roughly 17 nmol\/L above taking nothing, once levels settle. People respond differently, so the only way to know your own number is a 25-hydroxyvitamin D blood test.\u003c\/p\u003e\n\u003ch3\u003eWhy the D3 is dissolved in oil\u003c\/h3\u003e\n\u003cp\u003eVitamin D is fat-soluble, so it rides into your body along with fat. Here the D3 is already dissolved in fractionated coconut oil. A systematic review of head-to-head comparisons found that in healthy people, vitamin D in oil produced a bigger rise in blood 25-hydroxyvitamin D than vitamin D in a powder or an ethanol base (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20425758\/\"\u003ea review of how the carrier affects vitamin D absorption\u003c\/a\u003e). The honest limit: the reviewers found only four studies to compare.\u003c\/p\u003e\n\u003ch3\u003eVitamin D and calcium\u003c\/h3\u003e\n\u003cp\u003eVitamin D's best-known job is helping your gut absorb calcium. In a Creighton University study, people absorbed 65% more calcium from a 500 mg dose when their blood vitamin D averaged about 86 nmol\/L than at about 50 nmol\/L, and both numbers sit inside the normal reference range (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12672710\/\"\u003ea study of calcium absorption at two vitamin D levels\u003c\/a\u003e). It measured one calcium dose over 10 to 12 hours, not bones over years, so it shows the mechanism, not a bone outcome.†\u003c\/p\u003e\n\u003ch3\u003eVitamin D and your muscles\u003c\/h3\u003e\n\u003cp\u003eA meta-analysis of 30 randomized trials with 5,615 people (average age 61) found a small but statistically significant improvement in overall muscle strength with vitamin D, and no significant change in muscle mass or power (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25033068\/\"\u003ea meta-analysis of vitamin D and muscle strength\u003c\/a\u003e). The effect was bigger in people 65 and older and in people starting from very low blood levels, and close to zero in people under 65. Vitamin D is part of the foundation, not a substitute for picking up heavy things.†\u003c\/p\u003e\n\u003ch3\u003eVitamin D and the immune system\u003c\/h3\u003e\n\u003cp\u003eB cells, T cells and antigen-presenting cells all carry vitamin D receptors and can make the active form of vitamin D themselves, which lets vitamin D help regulate both your first-response (innate) and learned (adaptive) immune responses (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21527855\/\"\u003ea review of how vitamin D works in the immune system\u003c\/a\u003e).† Taking more than you need doesn't buy extra immunity, and we don't claim it does.\u003c\/p\u003e\n\u003ch2\u003eHow to take Everyday Liquid Sunshine\u003c\/h2\u003e\n\u003cp\u003eThe label directions, word for word: \"One drop of liquid sunshine for 1,000 IU (25 mcg) Vitamin D3 per day, as a dietary supplement.\" The label also says: \"Recommended for adult use only.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTake it with a meal that has some fat in it.\u003c\/strong\u003e Fat in the gut helps vitamin D absorption, per the NIH fact sheet.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdd up your vitamin D.\u003c\/strong\u003e Count the vitamin D on every label you take, multivitamins included. For adults, the Tolerable Upper Intake Level is 100 mcg (4,000 IU) a day from all sources. The NIH fact sheet lists \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminD-HealthProfessional\/\"\u003evitamin D upper limits by age and the medications that interact with vitamin D\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot that goes into Everyday Liquid Sunshine for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Everyday Liquid Sunshine gets its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley. Our formulators, makers and testers all work under one roof in a UL-certified cGMP facility, the owners work in the building too, and we've been owner-run since 2017. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much vitamin D is in one drop?\u003c\/h3\u003e\n\u003cp\u003eOne drop has 25 mcg (1,000 IU) of vitamin D3, 125% of the 20 mcg (800 IU) Daily Value. For comparison, the RDA is 15 mcg (600 IU) a day for adults 19 to 70 and 20 mcg (800 IU) over 70.\u003c\/p\u003e\n\u003ch3\u003eHow many servings are in a bottle?\u003c\/h3\u003e\n\u003cp\u003eThe label lists 1,400 one-drop servings in the 1 fl oz bottle. At $25.99, that's less than 2 cents a serving.\u003c\/p\u003e\n\u003ch3\u003eCan I take more than one drop a day?\u003c\/h3\u003e\n\u003cp\u003eThe label directs one drop a day, and that's what we recommend. If you think you need more, talk with your healthcare practitioner first, ideally with a 25-hydroxyvitamin D blood test in hand. The adult upper limit is 4,000 IU a day from all sources.\u003c\/p\u003e\n\u003ch3\u003eCan kids use Everyday Liquid Sunshine?\u003c\/h3\u003e\n\u003cp\u003eNo. The label says it is recommended for adult use only. For children, ask your pediatrician about a product and amount made for their age.\u003c\/p\u003e\n\u003ch3\u003eWhy a liquid drop instead of a capsule?\u003c\/h3\u003e\n\u003cp\u003eMostly preference: the D3 is already in oil and there's no pill to swallow. If you'd rather take a capsule, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-vitamin-d-60-caps\"\u003eGood Vitamin D, a 2,000 IU D3 capsule with bromelain\u003c\/a\u003e, is our one-capsule-a-day option.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with other Mt. Angel Vitamins products?\u003c\/h3\u003e\n\u003cp\u003eUsually yes, as long as you count your vitamin D. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/bones-k2-comprehensive-bone-supp\"\u003eBones + K2, our calcium, vitamin D3 and K2 bone formula\u003c\/a\u003e, already has 25 mcg (1,000 IU) of D3 per 2-capsule serving, so the two together add up to 2,000 IU a day. Our other vitamin D products contain D3 too, so pick one main vitamin D source rather than stacking several.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calcium-citrate-60ct\"\u003eCalcium Citrate, 250 mg of calcium per capsule with no added vitamin D\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/everyday-liquid-sunshine-2-d3-k2\"\u003eEveryday Liquid Sunshine 2, vitamin D3 and K2 in one liquid\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eTripkovic L et al. Daily supplementation with 15 μg vitamin D2 compared with vitamin D3 to increase wintertime 25-hydroxyvitamin D status in healthy South Asian and white European women: a 12-wk randomized, placebo-controlled food-fortification trial. The American journal of clinical nutrition. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28679555\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHeaney RP et al. Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. The American journal of clinical nutrition. 2003. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12499343\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eGrossmann RE et al. Evaluation of vehicle substances on vitamin D bioavailability: a systematic review. Molecular nutrition \u0026amp; food research. 2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20425758\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHeaney RP et al. Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. Journal of the American College of Nutrition. 2003. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12672710\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBeaudart C et al. The effects of vitamin D on skeletal muscle strength, muscle mass, and muscle power: a systematic review and meta-analysis of randomized controlled trials. The Journal of clinical endocrinology and metabolism. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25033068\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAranow C. Vitamin D and the immune system. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 2011. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21527855\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"1 fl oz","offer_id":44364424315162,"sku":"015-M2100","price":25.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M2100_REV02_Ingredients.png?v=1738258174"},{"product_id":"everyday-liquid-sunshine-2-d3-k2","title":"Everyday Liquid Sunshine 2 D3 + K2 – Bone \u0026 Immune Support | 2 fl oz Drops","description":"\u003cp\u003e\u003cstrong\u003eEveryday Liquid Sunshine 2 is a liquid vitamin D3 and K2 supplement. Each dropper squeeze gives you 5,000 IU (125 mcg) of vitamin D3 as cholecalciferol and 120 mcg of vitamin K2 as all-trans MK-7, dissolved in fractionated coconut oil and sunflower oil with natural orange flavor. One 2 fl oz bottle holds approximately 70 servings. It supports bone and immune system health.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWe're built to make vitamin D from sunlight on bare skin. Then life moved indoors, and an Oregon winter of short, cloudy days gives your skin little to work with. Everyday Liquid Sunshine 2 is for adults who know their vitamin D tends to run low (ideally because a blood test told them so), whose practitioner is comfortable with a higher daily dose, and who want D3 and K2 in one morning dropper. Aging isn't optional. Getting old is. Strong bones and a well-supported immune system are two things you'll want working in your 70s and 80s, and the habits behind them are worth starting in your 30s and 40s.†\u003c\/p\u003e\n\u003ch2\u003eWhy people take Everyday Liquid Sunshine 2\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCalcium absorption.\u003c\/strong\u003e Vitamin D3 helps your body absorb the calcium and phosphorus in your food, the raw materials of bone.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBone protein activation.\u003c\/strong\u003e Vitamin K2 activates osteocalcin, one of the main proteins in bone and part of normal bone mineralization.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNormal immune function.\u003c\/strong\u003e Vitamin D supports the immune system, and many immune cells carry vitamin D receptors.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMuscle function.\u003c\/strong\u003e Your muscles need vitamin D to work normally.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSteady vitamin D through darker months.\u003c\/strong\u003e One dropper squeeze a day helps maintain healthy vitamin D levels when sun exposure is limited.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin D3 (cholecalciferol)\u003c\/td\u003e\n\u003ctd\u003e125 mcg (5,000 IU)\u003c\/td\u003e\n\u003ctd\u003e625\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin K2 (all trans MK7)\u003c\/td\u003e\n\u003ctd\u003e120 mcg\u003c\/td\u003e\n\u003ctd\u003e100\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 1 Dropper Squeeze (~0.72 grams). Servings per container: Approx. 70. Other ingredients: Fractionated coconut oil, sunflower oil, and natural orange flavor. The label states: \"NO corn, soy, salt, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow Everyday Liquid Sunshine 2 works\u003c\/h2\u003e\n\u003ch3\u003eVitamin D3 (cholecalciferol), 5,000 IU\u003c\/h3\u003e\n\u003cp\u003eVitamin D3 is the same form your skin makes when UVB light hits it. Your liver turns it into 25-hydroxyvitamin D, the number a vitamin D blood test reports, and your kidneys turn that into calcitriol, the active form that tells your gut to absorb calcium and phosphorus.†\u003c\/p\u003e\n\u003cp\u003eWhy D3 and not D2? A 2012 meta-analysis of head-to-head randomized trials found D3 raised blood 25-hydroxyvitamin D more than D2 overall. The gap was clearest with large, infrequent doses and wasn't significant in the daily-dosing trials, so D3 works at least as well as D2, and better overall in the pooled trials (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22552031\/\"\u003eTripkovic 2012\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eVitamin D also reaches past bone: B cells, T cells and antigen-presenting cells all carry vitamin D receptors, and these immune cells can make active vitamin D themselves, which is part of how vitamin D supports normal immune function (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21527855\/\"\u003eAranow 2011\u003c\/a\u003e).†\u003c\/p\u003e\n\u003cp\u003eWhat the research doesn't show: that more vitamin D on top of adequate levels builds extra bone. A 2014 meta-analysis of 23 trials in 4,082 adults (average age 59) found a small bone density benefit at one hip site, about 0.8%, and none elsewhere. The authors concluded that routine vitamin D for bone density isn't supported in adults without risk factors for low vitamin D (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24119980\/\"\u003eReid 2014\u003c\/a\u003e).\u003c\/p\u003e\n\u003ch3\u003eVitamin K2 (all-trans MK-7), 120 mcg\u003c\/h3\u003e\n\u003cp\u003eVitamin K is a switch. It activates a family of proteins through a step called carboxylation. In the liver, those proteins handle normal blood clotting. In bone, one of the main ones is osteocalcin, a protein involved in bone mineralization, and it needs vitamin K to switch it on.† Vitamin K2 comes in several forms called menaquinones, and MK-7 is the long-chain form found in fermented foods like natto.\u003c\/p\u003e\n\u003cp\u003eWhy MK-7? In a study in healthy volunteers, vitamin K1 and MK-7 were both absorbed well, but MK-7 stayed in the blood far longer, gave steadier levels, built up to 7- to 8-fold higher levels with prolonged daily use, and activated more osteocalcin (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17158229\/\"\u003eSchurgers 2007\u003c\/a\u003e). The label specifies the all-trans form of MK-7.\u003c\/p\u003e\n\u003cp\u003eIs 120 mcg enough to matter? In a 12-week double-blind trial in 120 Japanese adults aged 20 to 69, 100 mcg of MK-7 a day raised the ratio of activated to inactive osteocalcin compared with placebo (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26875489\/\"\u003eInaba 2015\u003c\/a\u003e). One limit: that trial measured a marker of vitamin K activity in bone, not bone density or strength.\u003c\/p\u003e\n\u003ch3\u003eWhy D3 and K2 share a bottle\u003c\/h3\u003e\n\u003cp\u003eVitamin D3 helps your body absorb calcium from food. Vitamin K2 switches on osteocalcin, a bone protein involved in mineralization, the process that lays calcium into bone.† To be straight with you, the studies above tested each vitamin on its own, and long trials of this exact pairing are thin.\u003c\/p\u003e\n\u003ch3\u003eThe oil base\u003c\/h3\u003e\n\u003cp\u003eBoth vitamins are fat-soluble, so they come already dissolved in fractionated coconut oil and sunflower oil. Food fat helps too: in 50 healthy older adults given a single vitamin D3 dose, peak blood D3 was 32% higher with a breakfast containing fat than with a fat-free breakfast (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25441954\/\"\u003eDawson-Hughes 2015\u003c\/a\u003e). The natural orange flavor is there so the dropper tastes like something other than oil.\u003c\/p\u003e\n\u003ch2\u003eHow to take Everyday Liquid Sunshine 2\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDirections on the label:\u003c\/strong\u003e \"Take one serving by mouth in the morning.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eA breakfast with some fat in it, like eggs, nuts or avocado toast, is an easy pairing, per the study above.\u003c\/li\u003e\n\u003cli\u003eAt one serving a day, the bottle's approximately 70 servings last about 70 days.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. If you take warfarin or another blood thinner that works against vitamin K, talk to your prescriber first: the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminK-HealthProfessional\/\"\u003eNIH vitamin K fact sheet describes a serious interaction with warfarin\u003c\/a\u003e. The 5,000 IU (125 mcg) of D3 in each serving is above the 4,000 IU (100 mcg) daily upper limit that the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminD-HealthProfessional\/\"\u003eNIH vitamin D fact sheet lists for everyone 9 and older\u003c\/a\u003e, so use it with your practitioner's guidance and an occasional blood test. Ask a pediatrician before giving it to a child or teen, since 5,000 IU is above the upper limit for every age group. The same NIH vitamin D fact sheet lists other medicines that can interact with vitamin D.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cp\u003eWe've been making supplements in Oregon since 1974. Here's how we work today.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Everyday Liquid Sunshine 2 gets its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA, in Mt. Angel, Oregon.\u003c\/strong\u003e We make and test it there. Mt. Angel is a farm town of about 3,500 people in the Willamette Valley, home to our UL-certified cGMP facility. The formulators, makers and testers work under one roof, and the owners work in the building too. We've been owner-run since 2017. And no, we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much vitamin D3 and K2 is in each serving?\u003c\/h3\u003e\n\u003cp\u003eEach dropper squeeze has 5,000 IU (125 mcg) of vitamin D3 as cholecalciferol and 120 mcg of vitamin K2 as all-trans MK-7. That's 625% of the Daily Value for vitamin D and 100% for vitamin K.\u003c\/p\u003e\n\u003ch3\u003eIs 5,000 IU of vitamin D too much?\u003c\/h3\u003e\n\u003cp\u003eIt can be, depending on where your levels start. It's above the 4,000 IU daily upper limit for adults, so it makes the most sense when your practitioner has checked your 25-hydroxyvitamin D and wants you at this dose. For a smaller or adjustable amount, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/everyday-liquid-sunshine-bone-imm\"\u003eEveryday Liquid Sunshine has 1,000 IU of D3 per drop\u003c\/a\u003e, without the K2.\u003c\/p\u003e\n\u003ch3\u003eWhen should I take it, and does it need food?\u003c\/h3\u003e\n\u003cp\u003eTake it in the morning, as the label directs. Pairing it with a breakfast that has some fat in it is a sensible habit, since in one study a breakfast with fat raised peak blood vitamin D3 by 32% compared with a fat-free one.\u003c\/p\u003e\n\u003ch3\u003eHow long before I notice anything?\u003c\/h3\u003e\n\u003cp\u003eProbably not right away. Blood vitamin D climbs gradually over weeks to months, so a follow-up blood test after a few months of daily use tells you more than how you feel.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Bones + K2 or Calcium Citrate?\u003c\/h3\u003e\n\u003cp\u003eYes to Calcium Citrate: this formula has no calcium, and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calcium-citrate-60ct\"\u003eCalcium Citrate provides 250 mg of calcium per capsule\u003c\/a\u003e. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/bones-k2-comprehensive-bone-supp\"\u003eBones + K2 already has 25 mcg (1,000 IU) of vitamin D3 and 120 mcg of MK-7 per two-capsule serving\u003c\/a\u003e, so taking both daily adds up to 6,000 IU of D3 and 240 mcg of K2 a day. Check that total with your practitioner before doubling up.\u003c\/p\u003e\n\u003ch3\u003eI take a blood thinner. Can I use this?\u003c\/h3\u003e\n\u003cp\u003eTalk to your prescriber first. Vitamin K directly affects how warfarin-type blood thinners work, and the researchers who compared K1 and MK-7 cautioned that 50 mcg or more of MK-7 a day may interfere with those medicines. Each serving here has 120 mcg.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eTripkovic L et al. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. Am J Clin Nutr. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22552031\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAranow C. Vitamin D and the immune system. J Investig Med. 2011. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21527855\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eReid IR et al. Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis. Lancet. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24119980\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSchurgers LJ et al. Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17158229\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eInaba N et al. Low-Dose Daily Intake of Vitamin K(2) (Menaquinone-7) Improves Osteocalcin γ-Carboxylation: A Double-Blind, Randomized Controlled Trials. J Nutr Sci Vitaminol (Tokyo). 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26875489\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDawson-Hughes B et al. Dietary fat increases vitamin D-3 absorption. J Acad Nutr Diet. 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25441954\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"2 fl oz (1 bottle)","offer_id":44364422250778,"sku":"015-M2113","price":25.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M2113_REV02_Necktag.png?v=1738258716"}],"url":"https:\/\/www.mtangelvitamins.com\/collections\/liquid-chewable-vitamins.oembed","provider":"Mt. Angel Vitamins","version":"1.0","type":"link"}