{"title":"Liver Support Supplements","description":"\u003cp\u003eOur liver formulas support healthy liver function.† D-Tox combines NAC with milk thistle, Milk Thistle 200 mg is the single-ingredient classic, and LIV'R Support is another option for healthy liver function.†\u003c\/p\u003e","products":[{"product_id":"d-tox-healthy-liver-support","title":"D-Tox with NAC \u0026 Milk Thistle – Healthy Liver Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eD-Tox is a liver support supplement with 200 mg each of N-acetyl cysteine (NAC), burdock root, dandelion root, Oregon grape root and milk thistle seed extract standardized to 80% silymarin, plus 50 mg of DIM and 5 mg of D-limonene in every 2-capsule serving. Each bottle holds 60 vegetarian capsules. D-Tox supports healthy liver function.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eYour liver works around the clock, processing nutrients, hormones and the everyday compounds that come in with food, drink and air, and getting them ready to leave the body. D-Tox is for adults who want to back up that normal work with NAC, milk thistle and three roots with a long history in traditional herbal practice.†\u003c\/p\u003e\n\u003cp\u003eYou don't have to wait until your 50s to think about this. If you're in your 30s or 40s and already minding what you eat, how you sleep and how you move, D-Tox is an easy add. Small, steady habits now are how you add life to your years later. One honest note: D-Tox doesn't \"flush\" anything. It supports what your liver already does.†\u003c\/p\u003e\n\u003ch2\u003eWhy people take D-Tox\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy liver function.†\u003c\/li\u003e\n\u003cli\u003eProvides 200 mg of NAC per serving, a source of cysteine your body uses to make glutathione.†\u003c\/li\u003e\n\u003cli\u003eSupports the body's normal antioxidant defenses, with NAC as raw material for glutathione.†\u003c\/li\u003e\n\u003cli\u003eBrings together milk thistle, dandelion root, burdock root and Oregon grape root, four botanicals with a long history of traditional use for the liver.†\u003c\/li\u003e\n\u003cli\u003eAdds 50 mg of DIM, a compound that also forms when you eat broccoli and cabbage, studied for its role in how the body processes estrogen.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eN-Acetyl Cysteine\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBurdock Root (\u003cem\u003eArctium lappa\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDandelion Root (\u003cem\u003eTaraxacum officinale\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMilk Thistle Seed Extract (\u003cem\u003eSilybum marianum\u003c\/em\u003e, standardized to 80% silymarin)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOregon Grape Root (\u003cem\u003eMahonia aquifolium\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDiindolylmethane (DIM)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eD-Limonene\u003c\/td\u003e\n\u003ctd\u003e5 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 2 Vegetarian Capsules. Servings per container: 30 (60 capsules per bottle). Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), magnesium trisilicate, magnesium stearate, cellulose, and silica. The label states: \"NO corn, soy, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow D-Tox works\u003c\/h2\u003e\n\u003ch3\u003eN-acetyl cysteine (NAC): 200 mg\u003c\/h3\u003e\n\u003cp\u003eStart with glutathione, the most abundant small sulfur-containing antioxidant your cells make. Its two main jobs: it neutralizes oxidants, and it latches onto reactive compounds so the body can move them out (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18796312\/\"\u003ean overview of glutathione's protective roles\u003c\/a\u003e).† Your body builds glutathione from three amino acids (glutamate, cysteine and glycine), and NAC is a way to make more cysteine available for the job.\u003c\/p\u003e\n\u003cp\u003eNAC is cysteine with an acetyl group attached. Its main antioxidant role comes from helping cells raise their own glutathione, and its safety record is well established (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34208683\/\"\u003ea review of NAC and human health\u003c\/a\u003e).†\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29233792\/\"\u003ea 30-day double-blind crossover trial in 36 young men\u003c\/a\u003e sorted by their starting glutathione, NAC brought glutathione back up and lowered oxidative stress markers only in the low-glutathione group. In men who started moderate or high, it didn't change their antioxidant status. Limits: the dose was at least 1,200 mg of NAC a day, far more than a serving of D-Tox, and everyone was a young man. The takeaway we'd stand behind: NAC supports glutathione, and more doesn't help if you're already well supplied.†\u003c\/p\u003e\n\u003ch3\u003eMilk thistle seed extract: 200 mg, standardized to 80% silymarin\u003c\/h3\u003e\n\u003cp\u003eMilk thistle is a spiny, purple-flowered plant whose seeds have been used for the liver for centuries. The compounds that matter are called silymarin, a mix of flavonolignans such as silybin, silychristin and silydianin. \"Standardized to 80% silymarin\" means the extract is held to a set silymarin content, so each serving carries about 160 mg of silymarin. Plants vary; standardizing keeps the amount steady, and potency is one of the four tests every incoming ingredient lot gets.\u003c\/p\u003e\n\u003cp\u003eSilymarin is absorbed and processed fast. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17913795\/\"\u003ea small study in 3 healthy volunteers\u003c\/a\u003e given a single 600 mg dose of standardized extract, it showed up in the blood mostly as conjugates (water-soluble forms the body tags for removal), with half-lives of about 1 to 3 hours for the free forms and 3 to 8 hours for the conjugated forms. Three people is tiny, so read it as a sketch, but it's one reason splitting your capsules across two meals, as the label directs, makes sense.\u003c\/p\u003e\n\u003cp\u003eSilymarin also has a long safety record. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31069872\/\"\u003eAn updated review of silymarin safety\u003c\/a\u003e found it well tolerated in human studies, even at 700 mg three times a day for 24 weeks, with occasional stomach upset such as nausea or loose stools.\u003c\/p\u003e\n\u003ch3\u003eDandelion root and burdock root: 200 mg each\u003c\/h3\u003e\n\u003cp\u003eBoth are roots you may have pulled out of a garden, and burdock is also a vegetable, sold as gobo in Japanese grocery stores. Both are rich in inulin, a type of fiber, and herbalists have used both for the liver and digestion for generations. The straight version: human research on either root is thin and mostly lab and animal work. They're here for their traditional role alongside milk thistle, and we don't hang a separate promise on them.\u003c\/p\u003e\n\u003ch3\u003eOregon grape root: 200 mg\u003c\/h3\u003e\n\u003cp\u003eOregon grape (\u003cem\u003eMahonia aquifolium\u003c\/em\u003e) is a holly-leaved shrub native to the Pacific Northwest, and it's Oregon's state flower, so this one is close to home. Its bright yellow root gets its color from berberine and related alkaloids, and it has a long history as a traditional bitter. Human research on taking the root by mouth is limited, so it's a traditional companion here, not a headline. Berberine is also why anyone on medication should check with a practitioner first.\u003c\/p\u003e\n\u003ch3\u003eDIM: 50 mg\u003c\/h3\u003e\n\u003cp\u003eDiindolylmethane (DIM) forms in your stomach when indole-3-carbinol, from broccoli, cabbage, kale and Brussels sprouts, meets stomach acid. It's studied for its role in how the body processes estrogen. Most human DIM research is small and done in specific groups, so we don't make a hormone promise for it.\u003c\/p\u003e\n\u003ch3\u003eD-limonene: 5 mg\u003c\/h3\u003e\n\u003cp\u003eD-limonene is the compound that makes orange peel smell like orange peel. There's 5 mg here, and we make no claims for it. It's on the label, so it's on this page.\u003c\/p\u003e\n\u003ch2\u003eHow to take D-Tox\u003c\/h2\u003e\n\u003cp\u003eThe label's directions: \"One to two capsules twice daily, immediately before or during a meal, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eIn practice, that means taking it with two of your meals, such as breakfast and dinner. If you also take other products with milk thistle or NAC, add up the totals and run them by your practitioner.\u003c\/p\u003e\n\u003cp\u003eThe label warns: \"WARNING: Not recommended while pregnant or lactating unless directed by health care practitioner.\" It also carries this California Proposition 65 warning: \"WARNING: This product can expose you to chemicals including Lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.\"\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e52 years and counting.\u003c\/strong\u003e We've been making supplements in Oregon since 1974, and we're not getting old either.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\/d-tox-healthy-liver-support\"\u003eSee the certificates of analysis for this product\u003c\/a\u003e, listed by lot number.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps the formulators, the makers and the testers under one roof. The company has been owner-run since 2017, and the owners work in the building too.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many D-Tox capsules should I take a day?\u003c\/h3\u003e\n\u003cp\u003eFollow the label: one to two capsules twice daily, immediately before or during a meal. The Supplement Facts panel lists one serving as 2 capsules, and each 2-capsule serving gives you 200 mg of NAC and 200 mg of milk thistle seed extract.\u003c\/p\u003e\n\u003ch3\u003eDoes D-Tox flush toxins or cleanse my liver?\u003c\/h3\u003e\n\u003cp\u003eNo. D-Tox doesn't flush anything out of you. Your liver processes what comes in around the clock on its own, and D-Tox supplies NAC and botanicals that support that normal work.†\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eYou may not notice anything, and that's expected: supporting normal liver function happens out of sight.† Think of D-Tox as a steady daily habit, not a quick fix.\u003c\/p\u003e\n\u003ch3\u003eCan I take D-Tox with Milk Thistle or LIV'R Support?\u003c\/h3\u003e\n\u003cp\u003eYou can, but you'd be doubling up. Our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/milk-thistle-60-ct-vegetarian\"\u003eMilk Thistle\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/livr-support-liver-detox-cleanse\"\u003eLIV'R Support\u003c\/a\u003e both contain milk thistle extract too (LIV'R Support also has dandelion root and Oregon grape root), so add up the totals and check with your practitioner before stacking them.\u003c\/p\u003e\n\u003ch3\u003eIs D-Tox safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner or pharmacist first. Silymarin has few known drug interactions, but the safety review above advises caution with drugs that have a narrow therapeutic window, and the berberine in Oregon grape root can change how some medications are processed. Bring the bottle along.\u003c\/p\u003e\n\u003ch3\u003eWhy does the label carry a California Prop 65 warning?\u003c\/h3\u003e\n\u003cp\u003eCalifornia's Proposition 65 calls for a warning when a product could expose someone to a listed chemical, including lead, above levels the state sets. Our label carries it, so we repeat it word for word above. Every incoming ingredient lot is tested for heavy metals, and every lot of D-Tox has a certificate of analysis.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\"\u003eCertificates of analysis for our other products\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/milk-thistle-60-ct-vegetarian\"\u003eMilk Thistle, a single-herb liver option\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/livr-support-liver-detox-cleanse\"\u003eLIV'R Support, a broader liver formula\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eForman HJ et al. Glutathione: overview of its protective roles, measurement, and biosynthesis. Mol Aspects Med. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18796312\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eTenório MCDS et al. N-Acetylcysteine (NAC): Impacts on Human Health. Antioxidants (Basel). 2021. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34208683\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003ePaschalis V et al. N-acetylcysteine supplementation increases exercise performance and reduces oxidative stress only in individuals with low levels of glutathione. Free Radic Biol Med. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29233792\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWen Z et al. Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract. Drug Metab Dispos. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17913795\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSoleimani V et al. Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review. Phytother Res. 2019. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31069872\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364426739994,"sku":"010-A1004","price":27.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A1004_REV00_Necktag.png?v=1747784218"},{"product_id":"milk-thistle-60-ct-vegetarian","title":"Milk Thistle 200 mg – Supports Healthy Liver Function | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eMt. Angel Vitamins Milk Thistle is a single-ingredient herbal supplement. Each vegetarian capsule holds 200 mg of milk thistle fruit extract (\u003cem\u003eSilybum marianum\u003c\/em\u003e), standardized to contain 80% silybin\/silymarin, and each bottle has 60 capsules. The label directs one to two capsules twice daily. Milk thistle supports healthy liver function and the liver's normal antioxidant defenses.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eYour liver is one of the body's busiest processing plants. It sorts nutrients and handles the everyday compounds that come in with food and air, whether or not you ever think about it. Milk thistle is the herb people have used to back up that work for a very long time, and this bottle keeps it simple: one herb, one job, no blend to decode.\u003c\/p\u003e\n\u003cp\u003eIt's for adults who want straightforward liver support in their daily routine. Start in your 30s and 40s, when you're already paying attention to how you eat, sleep and move, because the habits you build now are the ones you'll live with in your 70s and 80s.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Milk Thistle\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy liver function.†\u003c\/li\u003e\n\u003cli\u003eSupports the liver's normal antioxidant defenses, helping liver cells handle everyday oxidative stress.†\u003c\/li\u003e\n\u003cli\u003eSilymarin helps cells turn up their own antioxidant enzymes, so it works with your body's defenses instead of acting only as a one-time antioxidant.†\u003c\/li\u003e\n\u003cli\u003eDelivers 200 mg of milk thistle fruit extract per capsule, standardized to 80% silybin\/silymarin, so you know what each capsule is built around.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eMilk Thistle Fruit Extract (\u003cem\u003eSilybum marianum\u003c\/em\u003e), standardized to contain 80% silybin\/silymarin\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 1 Vegetarian Capsule. At one capsule per serving, the 60-capsule bottle holds 60 servings. Other ingredients: Cellulose, vegetable cellulose (preservative-free, from capsule shell), magnesium trisilicate, and magnesium stearate. The label states: \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003cp\u003eAbout those other ingredients: cellulose is plant fiber, the capsule shell is vegetable cellulose, and magnesium trisilicate and magnesium stearate help the powder flow evenly so each capsule fills the same way.\u003c\/p\u003e\n\u003ch2\u003eHow Milk Thistle works\u003c\/h2\u003e\n\u003ch3\u003eMilk thistle, the plant\u003c\/h3\u003e\n\u003cp\u003eMilk thistle is a tall, prickly thistle with purple flower heads and leaves streaked with white veins, native to the Mediterranean. The label says \"fruit extract,\" and that's botanically precise: what most people call milk thistle seeds are tiny dry fruits, and that's where the plant keeps its silymarin.\u003c\/p\u003e\n\u003ch3\u003eSilymarin and the 80% standard\u003c\/h3\u003e\n\u003cp\u003eSilymarin isn't one compound. It's a family of plant compounds called flavonolignans, including silybin A and B, isosilybin A and B, silychristin and silydianin, all measured in human blood after a dose of standardized extract (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17913795\/\"\u003ea study of how silymarin compounds are absorbed and processed\u003c\/a\u003e). Silybin is the headliner. The panel on this bottle notes that silybin is considered the most characteristic and most stable of the flavonolignans in the plant, and this extract is standardized to contain 80% silybin\/silymarin.\u003c\/p\u003e\n\u003cp\u003ePlants vary from field to field and season to season, and standardizing takes that guesswork out. Potency is also one of the four checks every incoming ingredient lot gets before we use it, alongside identity, heavy metals and microbes.\u003c\/p\u003e\n\u003ch3\u003eHow silymarin supports the liver's antioxidant defenses\u003c\/h3\u003e\n\u003cp\u003eLiver cells do a lot of chemistry, and chemistry makes byproducts: reactive molecules called free radicals that cells are constantly cleaning up. Silymarin helps in more than one way. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26785346\/\"\u003eA review of silymarin's antioxidant mechanisms\u003c\/a\u003e concluded that grabbing free radicals directly matters mostly in the gut. Inside cells, the bigger effect is probably indirect: silymarin activates Nrf2, a switch that tells cells to make more of their own antioxidant enzymes and molecules.† Think of it less as a sponge and more as a foreman who gets the crew working.\u003c\/p\u003e\n\u003cp\u003eThe honest limit: most of that mechanism work comes from lab and animal studies. It explains how silymarin can support the liver's normal defenses. It isn't a measurement of what one capsule does in you.\u003c\/p\u003e\n\u003ch3\u003eHow your body absorbs it\u003c\/h3\u003e\n\u003cp\u003eSilymarin moves fast. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17913795\/\"\u003ea small study in three healthy volunteers\u003c\/a\u003e who took a single 600 mg dose of standardized extract, blood levels peaked within about 1 to 3 hours, and most of the silymarin was quickly converted into conjugated forms the body tags for removal. Half-lives were about 1 to 3 hours for the free forms and 3 to 8 hours for the conjugated forms. Three people is a sketch, not a verdict, but short half-lives fit with the label's twice-daily directions.\u003c\/p\u003e\n\u003ch3\u003eWhat the research does and doesn't show\u003c\/h3\u003e\n\u003cp\u003eMost human trials of milk thistle weren't run in healthy adults, so we don't borrow their results for this page. In healthy adults, the human research is mostly about how silymarin is absorbed and how well it's tolerated, not about results you'd feel.\u003c\/p\u003e\n\u003cp\u003eOn tolerance, the record is good. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31069872\/\"\u003eAn updated review of silymarin safety\u003c\/a\u003e found it well tolerated in people, even at 700 mg three times a day for 24 weeks, with occasional stomach upset such as nausea or loose stools. The label's top amount, two capsules twice a day, is 800 mg of extract a day. The same review describes few drug interactions but advises caution with medications that have a narrow safety margin, and urges caution and more study in pregnancy.\u003c\/p\u003e\n\u003cp\u003eOn medications specifically, \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25028567\/\"\u003ea 14-day study in nine healthy volunteers\u003c\/a\u003e taking a standardized milk thistle extract three times a day found no significant change in four major enzymes that process common drugs (CYP1A2, CYP2C9, CYP2D6 and CYP3A4\/5). Nine people and four enzymes don't cover every medication, which is why we still say: check with your practitioner.\u003c\/p\u003e\n\u003ch2\u003eHow to take Milk Thistle\u003c\/h2\u003e\n\u003cp\u003eThe label's directions: \"One to two capsules twice daily, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eThat works out to two to four capsules a day, split into two doses. If you also take another product that contains milk thistle, add up the totals.\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e52 years of making supplements.\u003c\/strong\u003e We've been making supplements in Oregon since 1974.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, milk thistle extract included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Milk Thistle has one. To see what one looks like, browse \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\"\u003ethe certificates of analysis we've published for other products\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA, in Mt. Angel, Oregon, with globally sourced ingredients.\u003c\/strong\u003e Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. We make and test Milk Thistle in our UL-certified cGMP facility there, where the formulators, the makers and the testers work under one roof, and the owners work in the building too. Owner-run since 2017, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eWhat does \"standardized to 80% silybin\/silymarin\" mean?\u003c\/h3\u003e\n\u003cp\u003eIt means the 200 mg of extract in each capsule is held to a set content of its key compounds: 80% silybin\/silymarin. Milk thistle plants vary, so standardizing is how you get the same capsule from bottle to bottle instead of whatever a given harvest produced.\u003c\/p\u003e\n\u003ch3\u003eHow many Milk Thistle capsules should I take a day?\u003c\/h3\u003e\n\u003cp\u003eFollow the label: one to two capsules twice daily. That's two to four capsules, or 400 to 800 mg of milk thistle fruit extract, a day. Starting at the low end and seeing how your stomach likes it is a sensible way to begin.\u003c\/p\u003e\n\u003ch3\u003eShould I take milk thistle with food?\u003c\/h3\u003e\n\u003cp\u003eThe label doesn't say either way, so take it however you'll remember it. Pairing the two doses with breakfast and dinner makes them easy to remember. If capsules on an empty stomach ever bother you, try them with a meal.\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eHonestly, you may never feel it, and that's normal for liver support. Milk thistle supports work your liver is already doing quietly, so think of it as a steady daily habit rather than something with a moment you'll notice.†\u003c\/p\u003e\n\u003ch3\u003eCan I take Milk Thistle with D-Tox or Liv'R Support?\u003c\/h3\u003e\n\u003cp\u003eYou can, but know that both already contain milk thistle. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/d-tox-healthy-liver-support\"\u003eD-Tox, our multi-ingredient liver support formula\u003c\/a\u003e, has 200 mg of milk thistle seed extract in each 2-capsule serving, alongside NAC and three roots. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/livr-support-liver-detox-cleanse\"\u003eLiv'R Support, our broader liver formula with choline and carnitine\u003c\/a\u003e, has 25 mg of milk thistle extract in each 2-capsule serving. If you combine them, add up the milk thistle and run the total by your practitioner.\u003c\/p\u003e\n\u003ch3\u003eIs milk thistle safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your practitioner before you start. Studies so far show few interactions, but they're small, and caution is advised with medications that have a narrow safety margin. Your practitioner knows your medication list. We don't.\u003c\/p\u003e\n\u003ch3\u003eIs Milk Thistle a detox or a cleanse?\u003c\/h3\u003e\n\u003cp\u003eNot in the cleanse sense. It doesn't flush or purge anything. Your liver does the everyday work of processing compounds and clearing them out on its own, and milk thistle supports that normal function.†\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eWen Z et al. Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract. Drug Metab Dispos. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17913795\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSurai PF. Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives. Antioxidants (Basel). 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26785346\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSoleimani V et al. Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review. Phytother Res. 2019. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31069872\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKawaguchi-Suzuki M et al. The effects of milk thistle (Silybum marianum) on human cytochrome P450 activity. Drug Metab Dispos. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25028567\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"Default Title","offer_id":49630166647066,"sku":"015-M1210","price":19.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1210_REV00_New_Item.png?v=1738258859"},{"product_id":"livr-support-liver-detox-cleanse","title":"LIV'R Support – Supports Healthy Liver Function | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eLIV'R Support is a liver formula with 300 mg of choline, 250 mg of carnitine, 150 mg each of L-methionine and inositol, 5 mg of vitamin B6, 50 mcg of chromium, 25 mg of milk thistle extract (80% silymarin) and 15 mg of Curcumin C3 Complex® per 2-capsule serving, plus eight plant ingredients at 0.5 to 15 mg each. Each bottle holds 60 vegetarian capsules. It supports healthy liver function.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eYour liver packages fat for transport, stores fuel and processes nearly everything you eat and drink. LIV'R Support backs that work with nutrients the liver uses, like choline and carnitine, plus traditional liver herbs.† It's an easy daily habit to start in your 30s and 40s. One candid note: it isn't a cleanse and doesn't flush anything out.\u003c\/p\u003e\n\u003ch2\u003eWhy people take LIV'R Support\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy liver function.†\u003c\/li\u003e\n\u003cli\u003eProvides 300 mg of choline (54% DV), which your liver uses to package fat and move it out.†\u003c\/li\u003e\n\u003cli\u003eSupports normal fat metabolism and energy production with 250 mg of carnitine.†\u003c\/li\u003e\n\u003cli\u003eAdds vitamin B6 and chromium to support normal protein and carbohydrate metabolism.†\u003c\/li\u003e\n\u003cli\u003eIncludes milk thistle extract and Curcumin C3 Complex® with Bioperine®, plant extracts studied for their antioxidant activity.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B6 (from pyridoxine HCl)\u003c\/td\u003e\n\u003ctd\u003e5 mg\u003c\/td\u003e\n\u003ctd\u003e294%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCholine (from 655 mg choline bitartrate)\u003c\/td\u003e\n\u003ctd\u003e300 mg\u003c\/td\u003e\n\u003ctd\u003e54%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eChromium (picolinate)\u003c\/td\u003e\n\u003ctd\u003e50 mcg\u003c\/td\u003e\n\u003ctd\u003e142%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCarnitine (from L-carnitine tartrate)\u003c\/td\u003e\n\u003ctd\u003e250 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eL-Methionine\u003c\/td\u003e\n\u003ctd\u003e150 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInositol\u003c\/td\u003e\n\u003ctd\u003e150 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMilk Thistle Standardized Extract (from \u003cem\u003eSilybum marianum\u003c\/em\u003e fruit, containing 80% silymarin)\u003c\/td\u003e\n\u003ctd\u003e25 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDandelion Root (\u003cem\u003eTaraxacum officinale\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eArtichoke Leaf (\u003cem\u003eCynara scolymus\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOregon Grape Root (\u003cem\u003eMahonia aquifolium\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCurcumin C3 Complex®\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBoldo Leaf (\u003cem\u003ePeumus boldo\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSchizandra Berry (\u003cem\u003eSchisandra chinensis\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGotu Kola Herb (\u003cem\u003eCentella asiatica\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e12.5 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBromelain 1200 GDU\/g (from \u003cem\u003eAnanas comosus\u003c\/em\u003e fruit)\u003c\/td\u003e\n\u003ctd\u003e12.5 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBioperine®\u003c\/td\u003e\n\u003ctd\u003e0.5 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 2 Vegetarian Capsules. Servings per container: 30. Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), magnesium trisilicate, silica, magnesium stearate, and cellulose.\u003c\/p\u003e\n\u003ch2\u003eHow LIV'R Support works\u003c\/h2\u003e\n\u003ch3\u003eCholine: 300 mg, from choline bitartrate\u003c\/h3\u003e\n\u003cp\u003eCholine is an essential nutrient. Your liver makes some, but not enough to meet your needs, per the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Choline-HealthProfessional\/\"\u003eNIH choline fact sheet\u003c\/a\u003e, and most people in the United States get less than the Adequate Intake (550 mg a day for men, 425 mg for women). The liver uses choline to build phosphatidylcholine, which it needs to package fat and ship it out.† Choline bitartrate is one of the main forms of choline in supplements.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17490963\/\"\u003ea controlled feeding study of 57 healthy adults\u003c\/a\u003e fed almost no choline for up to 42 days, most of the men and postmenopausal women showed signs that their liver or muscles weren't working normally, and normal function returned once choline was added back. That shows why choline matters, not what an extra 300 mg does if you already eat plenty.\u003c\/p\u003e\n\u003ch3\u003eCarnitine: 250 mg, from L-carnitine tartrate\u003c\/h3\u003e\n\u003cp\u003eIf choline helps the liver move fat out, carnitine helps cells burn it. It carries long-chain fatty acids into mitochondria to be turned into energy, per the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Carnitine-HealthProfessional\/\"\u003eNIH carnitine fact sheet\u003c\/a\u003e.† Healthy adults make their own from lysine and methionine, so the 250 mg here adds to that supply. L-carnitine tartrate supplies L-carnitine, one of the two main forms of carnitine found in supplements.\u003c\/p\u003e\n\u003ch3\u003eL-methionine and inositol: 150 mg each\u003c\/h3\u003e\n\u003cp\u003eMethionine is an essential amino acid, and the NIH choline fact sheet notes that how much methionine you get affects how much choline you need. Inositol is a building block of cell-membrane phospholipids. Research on these exact amounts is limited, so they're supporting cast.\u003c\/p\u003e\n\u003ch3\u003eVitamin B6 and chromium\u003c\/h3\u003e\n\u003cp\u003eVitamin B6 comes as pyridoxine HCl, the most common supplement form per the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB6-HealthProfessional\/\"\u003eNIH vitamin B6 fact sheet\u003c\/a\u003e. Your body converts it to coenzymes used in more than 100 enzyme reactions, mostly in protein metabolism.† The 5 mg here is well under the adult upper limit of 100 mg a day. Chromium picolinate supplies chromium, which the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Chromium-HealthProfessional\/\"\u003eNIH chromium fact sheet\u003c\/a\u003e says may play a role in how your body handles carbohydrate, fat and protein by boosting insulin's action.†\u003c\/p\u003e\n\u003ch3\u003eMilk thistle extract: 25 mg, 80% silymarin\u003c\/h3\u003e\n\u003cp\u003eMilk thistle's fruit (often called the seed) is a traditional liver herb. At 80% silymarin (its main group of compounds), each serving carries about 20 mg of silymarin. Straight talk: that's a modest amount. If milk thistle is what you're after, our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/milk-thistle-60-ct-vegetarian\"\u003esingle-herb Milk Thistle, with 200 mg of extract per capsule\u003c\/a\u003e, is the more direct pick. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31069872\/\"\u003eAn updated review of silymarin safety\u003c\/a\u003e found it well tolerated even at 700 mg three times a day for 24 weeks, with occasional stomach upset.\u003c\/p\u003e\n\u003ch3\u003eCurcumin C3 Complex® with Bioperine®: 15 mg and 0.5 mg\u003c\/h3\u003e\n\u003cp\u003eCurcumin C3 Complex® is a turmeric extract with at least 95% curcuminoids, per the label. The catch is absorption. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9619120\/\"\u003ean early study in healthy volunteers\u003c\/a\u003e, 2 g of curcumin alone left blood levels very low or undetectable, while adding 20 mg of piperine, the black pepper compound in Bioperine®, raised bioavailability by 2000%. The amounts here are far smaller, so that's the logic of the pairing, not a promise of those numbers.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23013352\/\"\u003ea 4-week placebo-controlled trial in 38 healthy adults aged 40 to 60\u003c\/a\u003e, 80 mg a day of a lipidated curcumin raised activity of catalase, an antioxidant enzyme your body makes, and the antioxidant capacity of saliva; placebo didn't. It was small, short and used a different form at over five times this amount, so we don't claim those results here.†\u003c\/p\u003e\n\u003ch3\u003eThe traditional herbs: 12.5 to 15 mg each\u003c\/h3\u003e\n\u003cp\u003eThe rest are herbs with long traditional use, plus one plant enzyme: dandelion root and artichoke leaf (classic European bitters), boldo leaf (from a Chilean shrub), Oregon grape root (the plant is Oregon's state flower), schizandra berry (traditional Chinese practice), gotu kola (Ayurvedic tradition) and bromelain (pineapple enzymes, 1200 GDU\/g). These are small amounts, so they're traditional companions, with no separate promises attached.\u003c\/p\u003e\n\u003ch2\u003eHow to take LIV'R Support\u003c\/h2\u003e\n\u003cp\u003eThe label's directions: \"One capsule, twice daily with meals, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eFor example, one with breakfast and one with dinner. Taking a multivitamin or another liver formula too? Add up your B6, chromium and milk thistle totals.\u003c\/p\u003e\n\u003cp\u003eThe label warns: \"WARNING: Not recommended while pregnant or lactating unless directed by health care practitioner.\" It also carries this California Proposition 65 warning: \"WARNING: This product can expose you to chemicals including Lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.\"\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e52 years and counting.\u003c\/strong\u003e We've been making supplements in Oregon since 1974, and we're not getting old either.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e LIV'R Support included, and you can browse \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\"\u003ecertificates of analysis published for other products\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA with globally sourced ingredients, in Mt. Angel, Oregon.\u003c\/strong\u003e Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps formulators, makers and testers under one roof, and it's been owner-run since 2017, with the owners working in the building. Here's \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/why-choose-us\"\u003ehow we make and test our supplements\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many LIV'R Support capsules do I take a day?\u003c\/h3\u003e\n\u003cp\u003eTwo: one capsule twice daily with meals, per the label. That's one serving a day, so a 60-capsule bottle lasts 30 days.\u003c\/p\u003e\n\u003ch3\u003eIs LIV'R Support a detox or a cleanse?\u003c\/h3\u003e\n\u003cp\u003eNo. It doesn't flush anything out of you. Your liver does its own processing around the clock, and LIV'R Support supplies nutrients that support its normal function.†\u003c\/p\u003e\n\u003ch3\u003eHow is LIV'R Support different from Milk Thistle and D-Tox?\u003c\/h3\u003e\n\u003cp\u003eLIV'R Support leads with 300 mg of choline and 250 mg of carnitine, with herbs in smaller amounts. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/milk-thistle-60-ct-vegetarian\"\u003eMilk Thistle\u003c\/a\u003e is a single herb at 200 mg of extract per capsule. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/d-tox-healthy-liver-support\"\u003eD-Tox\u003c\/a\u003e has 200 mg each of NAC, milk thistle extract, dandelion root, burdock root and Oregon grape root per 2-capsule serving, plus DIM and D-limonene. If you combine them, you'd double up on milk thistle and other herbs, so add up the totals and check with your practitioner.\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eYou may not feel anything, and that's expected, because your liver works out of sight. Think of LIV'R Support as a daily habit, not a quick fix.\u003c\/p\u003e\n\u003ch3\u003eIs LIV'R Support safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner or pharmacist first. The silymarin review above advises caution with drugs that have a narrow therapeutic window, and piperine slows one of the ways the liver and gut clear compounds, which could affect some medications too.\u003c\/p\u003e\n\u003ch3\u003eWhy does the label carry a Prop 65 warning?\u003c\/h3\u003e\n\u003cp\u003eCalifornia's Proposition 65 calls for a warning when a product could expose someone to a listed chemical, such as lead, above levels the state sets. We repeat our label's warning word for word above.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eFischer LM et al. Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17490963\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSoleimani V et al. Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review. Phytother Res. 2019. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31069872\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eShoba G et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9619120\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDiSilvestro RA et al. Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people. Nutr J. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23013352\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"Default Title","offer_id":50650805698842,"sku":"015-M1152","price":25.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1152_REV00_New_Item_Badge.png?v=1747783942"}],"url":"https:\/\/www.mtangelvitamins.com\/collections\/liver-support-supplements.oembed","provider":"Mt. Angel Vitamins","version":"1.0","type":"link"}