{"title":"Targeted Support","description":"\u003cp\u003eTargeted support is extra help where the years ask for it: bones and joints, sleep, stress, heart and circulation, eyes, immunity, digestion and liver. Many of these are classics people have counted on for years, kept current as the research moves. Keep your everyday essentials, then add one or two products for the goals that matter most to you.\u003c\/p\u003e","products":[{"product_id":"cold-facts-vitamin-d-immune-herbs","title":"Cold Facts + Vitamin D – Immune Support With Herbs | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eCold Facts + Vitamin D is an immune support supplement with 125 mcg (5,000 IU) of vitamin D3, 15 mg of zinc from zinc citrate, 1 mg of copper and 10 mg of niacin in every 2-capsule serving, plus American ginseng, echinacea, elderberry, astragalus, garlic, horehound, ginger, mullein and Bioperine®. Each bottle holds 60 vegetarian capsules. It supports normal immune function.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCold Facts + Vitamin D is for adults who would rather keep one bottle on the counter than six. It pairs nutrients immune cells use every day (vitamin D, zinc and copper) with a traditional herb blend. Fair warning: it leans hard on vitamin D, so it suits people who get little sun and have cleared a higher daily amount with their practitioner.\u003c\/p\u003e\n\u003cp\u003eIf you're in your 30s or 40s and already working on sleep, training and what's on your plate, this is the easy part. Small habits kept for decades are how you add life to your years.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Cold Facts + Vitamin D\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports normal immune function with vitamin D3, zinc and copper, three nutrients immune cells rely on.†\u003c\/li\u003e\n\u003cli\u003eProvides 125 mcg (5,000 IU) of vitamin D3, the form your skin makes from sunlight, to help maintain healthy vitamin D levels when sunshine is scarce.†\u003c\/li\u003e\n\u003cli\u003eDelivers 15 mg of zinc as zinc citrate, with 1 mg of copper to keep the two minerals in balance.†\u003c\/li\u003e\n\u003cli\u003eIncludes niacin (vitamin B3), which supports normal energy metabolism.†\u003c\/li\u003e\n\u003cli\u003ePuts eight traditional herbs, including American ginseng, echinacea root and elderberry, into the same two capsules.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin D (cholecalciferol)\u003c\/td\u003e\n\u003ctd\u003e125 mcg\u003c\/td\u003e\n\u003ctd\u003e625%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNiacin\u003c\/td\u003e\n\u003ctd\u003e10 mg NE\u003c\/td\u003e\n\u003ctd\u003e62%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eZinc (citrate)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003e136%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCopper (gluconate)\u003c\/td\u003e\n\u003ctd\u003e1 mg\u003c\/td\u003e\n\u003ctd\u003e111%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGarlic Bulb (Allium sativum)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAmerican Ginseng Root 4:1 Extract (Panax quinquefolius)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEchinacea Root 4:1 Extract (Echinacea purpurea)\u003c\/td\u003e\n\u003ctd\u003e150 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eElderberry Fruit 4:1 Extract (Sambucus nigra)\u003c\/td\u003e\n\u003ctd\u003e150 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAstragalus Root 4:1 Extract (Astragalus membrabaceus)\u003c\/td\u003e\n\u003ctd\u003e125 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHorehound Leaf (Marrubium vulgare)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGinger Root (Zingiber officinale)\u003c\/td\u003e\n\u003ctd\u003e25 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMullein Leaf 4:1 Extract (Verbascum thapsis)\u003c\/td\u003e\n\u003ctd\u003e25 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBioperine®\u003c\/td\u003e\n\u003ctd\u003e5 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 2 vegetarian capsules. Servings per container: 30, in a 60-capsule bottle. Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), L-leucine, and silica. The label states: \"NO soy, salt, yeast, wheat, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow Cold Facts + Vitamin D works\u003c\/h2\u003e\n\u003ch3\u003eVitamin D3: 125 mcg (5,000 IU)\u003c\/h3\u003e\n\u003cp\u003eMost people know vitamin D for bones, but immune cells use it too. B cells, T cells and antigen-presenting cells carry vitamin D receptors and can make active vitamin D right where they work, which lets vitamin D help regulate normal innate and adaptive immune responses (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21527855\/\"\u003ea review of vitamin D and the immune system\u003c\/a\u003e).†\u003c\/p\u003e\n\u003cp\u003eThis is D3 (cholecalciferol), not D2. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22552031\/\"\u003eA 2012 meta-analysis of trials comparing the two\u003c\/a\u003e found D3 raised blood vitamin D more. Straight talk: the gap was clearest with large single doses, and in daily-dose trials it wasn't statistically significant.\u003c\/p\u003e\n\u003cp\u003eThe amount is high, and we'd rather you hear it from us. 125 mcg is above the 100 mcg (4,000 IU) adult Tolerable Upper Intake Level, which \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminD-HealthProfessional\/\"\u003ethe NIH Office of Dietary Supplements vitamin D fact sheet\u003c\/a\u003e describes as the maximum daily intake unlikely to cause harmful effects. Talk with your practitioner, consider a blood test, and don't stack it with other vitamin D.\u003c\/p\u003e\n\u003ch3\u003eZinc citrate and copper gluconate: 15 mg and 1 mg\u003c\/h3\u003e\n\u003cp\u003eZinc ions help carry signals inside both innate and adaptive immune cells (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29186856\/\"\u003ea review of zinc's role in immune function\u003c\/a\u003e).† Why citrate? In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24259556\/\"\u003ea randomized crossover study in 15 healthy adults\u003c\/a\u003e, zinc citrate was absorbed about as well as zinc gluconate (about 61% each) and more than zinc oxide (about 50%). That study used 10 mg without food, so it's a guide, not a perfect match.\u003c\/p\u003e\n\u003cp\u003eThe 1 mg of copper is there for balance. \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Zinc-HealthProfessional\/\"\u003eThe NIH Office of Dietary Supplements zinc fact sheet\u003c\/a\u003e notes that 50 mg or more of zinc a day for weeks can interfere with copper absorption. Copper also plays its own part in normal immune function.†\u003c\/p\u003e\n\u003ch3\u003eNiacin: 10 mg\u003c\/h3\u003e\n\u003cp\u003eNiacin is vitamin B3. Your body turns it into NAD, a helper molecule cells use to pull energy out of food.† The 10 mg NE (niacin equivalents) is a top-up at 62% of the Daily Value.\u003c\/p\u003e\n\u003ch3\u003eAmerican ginseng and astragalus: 200 mg and 125 mg\u003c\/h3\u003e\n\u003cp\u003eAmerican ginseng is the North American cousin of Asian ginseng, and \"4:1 extract\" means about 4 parts of dried root went into 1 part extract. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18923572\/\"\u003ea small crossover trial in 10 healthy men\u003c\/a\u003e, 1,125 mg a day of a standardized North American ginseng extract for 35 days shifted two immune measures and left the rest, including white cell counts, unchanged. The researchers called the effect limited, and our 200 mg extract is a different preparation.\u003c\/p\u003e\n\u003cp\u003eAstragalus is a root used for centuries in traditional Chinese herbal practice. Most of its immune research is on purified polysaccharides in cell and animal studies, not root extracts in healthy people, so we make no specific claim for it.\u003c\/p\u003e\n\u003ch3\u003eEchinacea root and elderberry: 150 mg each\u003c\/h3\u003e\n\u003cp\u003eEchinacea is the purple coneflower of North American prairies, and the human data in healthy adults are mixed. When \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12218779\/\"\u003e40 healthy young men took pressed echinacea juice for two weeks in a placebo-controlled crossover trial\u003c\/a\u003e, the immune-cell activity researchers measured didn't change. That juice came from the above-ground plant, not the root, so it doesn't settle the question for a root extract.\u003c\/p\u003e\n\u003cp\u003eElderberry is the dark purple fruit of the European elder, colored by anthocyanins, plant pigments that act as antioxidants in lab tests. We didn't find solid trials in healthy adults at this amount, so it's here as a traditional herb, not a promise.\u003c\/p\u003e\n\u003ch3\u003eGarlic, horehound, ginger and mullein\u003c\/h3\u003e\n\u003cp\u003eGarlic bulb (200 mg) is the familiar kitchen bulb, best known for alliin, a sulfur compound that turns into allicin when a clove is crushed. Horehound (100 mg) is the bitter mint-family herb behind old-fashioned horehound candy. Ginger root (25 mg) and mullein leaf extract (25 mg) round out the blend in small, traditional amounts.\u003c\/p\u003e\n\u003ch3\u003eBioperine®: 5 mg\u003c\/h3\u003e\n\u003cp\u003eBioperine® is a black pepper extract standardized for piperine, the compound that gives pepper its bite. Piperine has raised blood levels of some compounds taken with it in research, but that hasn't been tested for this formula, so we don't claim it.\u003c\/p\u003e\n\u003ch2\u003eHow to take Cold Facts + Vitamin D\u003c\/h2\u003e\n\u003cp\u003eLabel directions: \"Two capsules, preferably with a meal, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eVitamin D is fat-soluble, so a meal with a little fat is a natural fit. Before adding other products, total up your vitamin D and zinc (see the FAQ).\u003c\/p\u003e\n\u003cp\u003eLabel warning: \"Not recommended while pregnant or lactating unless directed by health care practitioner.\" Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. Keep it away from children: one serving is above the vitamin D upper limit for every child age group.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cp\u003eWe've been making supplements in Oregon since 1974. Here's what stands behind every bottle.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, herbs included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Cold Facts + Vitamin D has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps formulators, makers and testers under one roof, the owners work in the building too, and the company has been owner-run since 2017.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much vitamin D is in Cold Facts + Vitamin D?\u003c\/h3\u003e\n\u003cp\u003eEach 2-capsule serving has 125 mcg (5,000 IU) of vitamin D3, 625% of the Daily Value. That's above the 100 mcg (4,000 IU) adult upper limit, so check with your practitioner before taking it every day long term.\u003c\/p\u003e\n\u003ch3\u003eWhen should I take it, and does it need food?\u003c\/h3\u003e\n\u003cp\u003eTake it with a meal. The label says two capsules, preferably with a meal, and names no time of day, so pick the meal you never skip.\u003c\/p\u003e\n\u003ch3\u003eHow long does a bottle last?\u003c\/h3\u003e\n\u003cp\u003eA bottle holds 30 servings of 2 capsules, a 30-day supply at one serving a day.\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eMost people won't feel it day to day, and that's normal. These nutrients work in the background of normal immune function, and blood vitamin D rises gradually over weeks of steady use.† Consistency is the point.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with other Mt. Angel Vitamins products?\u003c\/h3\u003e\n\u003cp\u003eYes, but add up the overlap first. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-vitamin-d-60-caps\"\u003eGood Vitamin D\u003c\/a\u003e adds 50 mcg of vitamin D3 per capsule and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/everyday-liquid-sunshine-2-d3-k2\"\u003eEveryday Liquid Sunshine 2\u003c\/a\u003e adds 125 mcg per serving, so most people should pick one vitamin D product unless their practitioner says otherwise. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/quercetin-zinc\"\u003eQuercetin Zinc\u003c\/a\u003e adds 7.5 mg of zinc and 25 mcg of D3 per serving. Our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/advanced-zinc-citrate-50mg\"\u003eZinc 50 mg Citrate Chelate\u003c\/a\u003e plus Cold Facts comes to 65 mg of zinc a day, above the 40 mg adult upper limit, so skip that pairing unless your practitioner directs it.\u003c\/p\u003e\n\u003ch3\u003eIs it safe with medication or while pregnant?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first. The label says it's not recommended while pregnant or lactating unless directed by a health care practitioner, and garlic, ginseng, echinacea and piperine can each interact with some prescription drugs.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eAranow C. Vitamin D and the immune system. J Investig Med. 2011. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21527855\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eTripkovic L et al. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. Am J Clin Nutr. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22552031\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWessels I et al. Zinc as a Gatekeeper of Immune Function. Nutrients. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29186856\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWegmüller R et al. Zinc absorption by young adults from supplemental zinc citrate is comparable with that from zinc gluconate and higher than from zinc oxide. J Nutr. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24259556\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBiondo PD et al. A randomized controlled crossover trial of the effect of ginseng consumption on the immune response to moderate exercise in healthy sedentary men. Appl Physiol Nutr Metab. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18923572\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSchwarz E et al. Oral administration of freshly expressed juice of Echinacea purpurea herbs fail to stimulate the nonspecific immune response in healthy young men: results of a double-blind, placebo-controlled crossover study. J Immunother. 2002. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12218779\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364426772762,"sku":"015-A1003","price":31.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A1003_REV00_Necktag.png?v=1738590171"},{"product_id":"d-tox-healthy-liver-support","title":"D-Tox with NAC \u0026 Milk Thistle – Healthy Liver Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eD-Tox is a liver support supplement with 200 mg each of N-acetyl cysteine (NAC), burdock root, dandelion root, Oregon grape root and milk thistle seed extract standardized to 80% silymarin, plus 50 mg of DIM and 5 mg of D-limonene in every 2-capsule serving. Each bottle holds 60 vegetarian capsules. D-Tox supports healthy liver function.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eYour liver works around the clock, processing nutrients, hormones and the everyday compounds that come in with food, drink and air, and getting them ready to leave the body. D-Tox is for adults who want to back up that normal work with NAC, milk thistle and three roots with a long history in traditional herbal practice.†\u003c\/p\u003e\n\u003cp\u003eYou don't have to wait until your 50s to think about this. If you're in your 30s or 40s and already minding what you eat, how you sleep and how you move, D-Tox is an easy add. Small, steady habits now are how you add life to your years later. One honest note: D-Tox doesn't \"flush\" anything. It supports what your liver already does.†\u003c\/p\u003e\n\u003ch2\u003eWhy people take D-Tox\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy liver function.†\u003c\/li\u003e\n\u003cli\u003eProvides 200 mg of NAC per serving, a source of cysteine your body uses to make glutathione.†\u003c\/li\u003e\n\u003cli\u003eSupports the body's normal antioxidant defenses, with NAC as raw material for glutathione.†\u003c\/li\u003e\n\u003cli\u003eBrings together milk thistle, dandelion root, burdock root and Oregon grape root, four botanicals with a long history of traditional use for the liver.†\u003c\/li\u003e\n\u003cli\u003eAdds 50 mg of DIM, a compound that also forms when you eat broccoli and cabbage, studied for its role in how the body processes estrogen.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eN-Acetyl Cysteine\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBurdock Root (\u003cem\u003eArctium lappa\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDandelion Root (\u003cem\u003eTaraxacum officinale\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMilk Thistle Seed Extract (\u003cem\u003eSilybum marianum\u003c\/em\u003e, standardized to 80% silymarin)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOregon Grape Root (\u003cem\u003eMahonia aquifolium\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDiindolylmethane (DIM)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eD-Limonene\u003c\/td\u003e\n\u003ctd\u003e5 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 2 Vegetarian Capsules. Servings per container: 30 (60 capsules per bottle). Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), magnesium trisilicate, magnesium stearate, cellulose, and silica. The label states: \"NO corn, soy, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow D-Tox works\u003c\/h2\u003e\n\u003ch3\u003eN-acetyl cysteine (NAC): 200 mg\u003c\/h3\u003e\n\u003cp\u003eStart with glutathione, the most abundant small sulfur-containing antioxidant your cells make. Its two main jobs: it neutralizes oxidants, and it latches onto reactive compounds so the body can move them out (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18796312\/\"\u003ean overview of glutathione's protective roles\u003c\/a\u003e).† Your body builds glutathione from three amino acids (glutamate, cysteine and glycine), and NAC is a way to make more cysteine available for the job.\u003c\/p\u003e\n\u003cp\u003eNAC is cysteine with an acetyl group attached. Its main antioxidant role comes from helping cells raise their own glutathione, and its safety record is well established (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34208683\/\"\u003ea review of NAC and human health\u003c\/a\u003e).†\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29233792\/\"\u003ea 30-day double-blind crossover trial in 36 young men\u003c\/a\u003e sorted by their starting glutathione, NAC brought glutathione back up and lowered oxidative stress markers only in the low-glutathione group. In men who started moderate or high, it didn't change their antioxidant status. Limits: the dose was at least 1,200 mg of NAC a day, far more than a serving of D-Tox, and everyone was a young man. The takeaway we'd stand behind: NAC supports glutathione, and more doesn't help if you're already well supplied.†\u003c\/p\u003e\n\u003ch3\u003eMilk thistle seed extract: 200 mg, standardized to 80% silymarin\u003c\/h3\u003e\n\u003cp\u003eMilk thistle is a spiny, purple-flowered plant whose seeds have been used for the liver for centuries. The compounds that matter are called silymarin, a mix of flavonolignans such as silybin, silychristin and silydianin. \"Standardized to 80% silymarin\" means the extract is held to a set silymarin content, so each serving carries about 160 mg of silymarin. Plants vary; standardizing keeps the amount steady, and potency is one of the four tests every incoming ingredient lot gets.\u003c\/p\u003e\n\u003cp\u003eSilymarin is absorbed and processed fast. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17913795\/\"\u003ea small study in 3 healthy volunteers\u003c\/a\u003e given a single 600 mg dose of standardized extract, it showed up in the blood mostly as conjugates (water-soluble forms the body tags for removal), with half-lives of about 1 to 3 hours for the free forms and 3 to 8 hours for the conjugated forms. Three people is tiny, so read it as a sketch, but it's one reason splitting your capsules across two meals, as the label directs, makes sense.\u003c\/p\u003e\n\u003cp\u003eSilymarin also has a long safety record. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31069872\/\"\u003eAn updated review of silymarin safety\u003c\/a\u003e found it well tolerated in human studies, even at 700 mg three times a day for 24 weeks, with occasional stomach upset such as nausea or loose stools.\u003c\/p\u003e\n\u003ch3\u003eDandelion root and burdock root: 200 mg each\u003c\/h3\u003e\n\u003cp\u003eBoth are roots you may have pulled out of a garden, and burdock is also a vegetable, sold as gobo in Japanese grocery stores. Both are rich in inulin, a type of fiber, and herbalists have used both for the liver and digestion for generations. The straight version: human research on either root is thin and mostly lab and animal work. They're here for their traditional role alongside milk thistle, and we don't hang a separate promise on them.\u003c\/p\u003e\n\u003ch3\u003eOregon grape root: 200 mg\u003c\/h3\u003e\n\u003cp\u003eOregon grape (\u003cem\u003eMahonia aquifolium\u003c\/em\u003e) is a holly-leaved shrub native to the Pacific Northwest, and it's Oregon's state flower, so this one is close to home. Its bright yellow root gets its color from berberine and related alkaloids, and it has a long history as a traditional bitter. Human research on taking the root by mouth is limited, so it's a traditional companion here, not a headline. Berberine is also why anyone on medication should check with a practitioner first.\u003c\/p\u003e\n\u003ch3\u003eDIM: 50 mg\u003c\/h3\u003e\n\u003cp\u003eDiindolylmethane (DIM) forms in your stomach when indole-3-carbinol, from broccoli, cabbage, kale and Brussels sprouts, meets stomach acid. It's studied for its role in how the body processes estrogen. Most human DIM research is small and done in specific groups, so we don't make a hormone promise for it.\u003c\/p\u003e\n\u003ch3\u003eD-limonene: 5 mg\u003c\/h3\u003e\n\u003cp\u003eD-limonene is the compound that makes orange peel smell like orange peel. There's 5 mg here, and we make no claims for it. It's on the label, so it's on this page.\u003c\/p\u003e\n\u003ch2\u003eHow to take D-Tox\u003c\/h2\u003e\n\u003cp\u003eThe label's directions: \"One to two capsules twice daily, immediately before or during a meal, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eIn practice, that means taking it with two of your meals, such as breakfast and dinner. If you also take other products with milk thistle or NAC, add up the totals and run them by your practitioner.\u003c\/p\u003e\n\u003cp\u003eThe label warns: \"WARNING: Not recommended while pregnant or lactating unless directed by health care practitioner.\" It also carries this California Proposition 65 warning: \"WARNING: This product can expose you to chemicals including Lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.\"\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e52 years and counting.\u003c\/strong\u003e We've been making supplements in Oregon since 1974, and we're not getting old either.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\/d-tox-healthy-liver-support\"\u003eSee the certificates of analysis for this product\u003c\/a\u003e, listed by lot number.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps the formulators, the makers and the testers under one roof. The company has been owner-run since 2017, and the owners work in the building too.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many D-Tox capsules should I take a day?\u003c\/h3\u003e\n\u003cp\u003eFollow the label: one to two capsules twice daily, immediately before or during a meal. The Supplement Facts panel lists one serving as 2 capsules, and each 2-capsule serving gives you 200 mg of NAC and 200 mg of milk thistle seed extract.\u003c\/p\u003e\n\u003ch3\u003eDoes D-Tox flush toxins or cleanse my liver?\u003c\/h3\u003e\n\u003cp\u003eNo. D-Tox doesn't flush anything out of you. Your liver processes what comes in around the clock on its own, and D-Tox supplies NAC and botanicals that support that normal work.†\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eYou may not notice anything, and that's expected: supporting normal liver function happens out of sight.† Think of D-Tox as a steady daily habit, not a quick fix.\u003c\/p\u003e\n\u003ch3\u003eCan I take D-Tox with Milk Thistle or LIV'R Support?\u003c\/h3\u003e\n\u003cp\u003eYou can, but you'd be doubling up. Our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/milk-thistle-60-ct-vegetarian\"\u003eMilk Thistle\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/livr-support-liver-detox-cleanse\"\u003eLIV'R Support\u003c\/a\u003e both contain milk thistle extract too (LIV'R Support also has dandelion root and Oregon grape root), so add up the totals and check with your practitioner before stacking them.\u003c\/p\u003e\n\u003ch3\u003eIs D-Tox safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner or pharmacist first. Silymarin has few known drug interactions, but the safety review above advises caution with drugs that have a narrow therapeutic window, and the berberine in Oregon grape root can change how some medications are processed. Bring the bottle along.\u003c\/p\u003e\n\u003ch3\u003eWhy does the label carry a California Prop 65 warning?\u003c\/h3\u003e\n\u003cp\u003eCalifornia's Proposition 65 calls for a warning when a product could expose someone to a listed chemical, including lead, above levels the state sets. Our label carries it, so we repeat it word for word above. Every incoming ingredient lot is tested for heavy metals, and every lot of D-Tox has a certificate of analysis.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\"\u003eCertificates of analysis for our other products\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/milk-thistle-60-ct-vegetarian\"\u003eMilk Thistle, a single-herb liver option\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/livr-support-liver-detox-cleanse\"\u003eLIV'R Support, a broader liver formula\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eForman HJ et al. Glutathione: overview of its protective roles, measurement, and biosynthesis. Mol Aspects Med. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18796312\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eTenório MCDS et al. N-Acetylcysteine (NAC): Impacts on Human Health. Antioxidants (Basel). 2021. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34208683\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003ePaschalis V et al. N-acetylcysteine supplementation increases exercise performance and reduces oxidative stress only in individuals with low levels of glutathione. Free Radic Biol Med. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29233792\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWen Z et al. Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract. Drug Metab Dispos. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17913795\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSoleimani V et al. Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review. Phytother Res. 2019. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31069872\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364426739994,"sku":"010-A1004","price":27.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A1004_REV00_Necktag.png?v=1747784218"},{"product_id":"inflameze-botanical-joint-support","title":"Inflameze – Botanical Joint Comfort Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eInflameze is a botanical joint support supplement with 150 mg of Boswellia serrata extract, 100 mg of bromelain, 100 mg of quercetin and 50 mg of Curcumin C3 Complex (turmeric curcuminoids) in every 1-capsule serving, plus devil's claw root, yucca root extract and alfalfa leaf. Each bottle holds 60 vegetarian capsules, taken one capsule twice daily, to support joint comfort and flexibility.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eInflameze is for active adults who want their joints to keep up with their plans, like the runner still logging miles at 45. It puts the three ingredients named on the front of the bottle (boswellia, bromelain and turmeric) into one small capsule, so you're not lining up five bottles on the counter.\u003c\/p\u003e\n\u003cp\u003eAging isn't optional. Getting old is. Joints are often where people first feel the difference, and the habits that matter (strength work, walking, sleep, decent food) pay off most when you start in your 30s and 40s. Inflameze is one small, steady part of that routine, not a stand-in for any of it.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Inflameze\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports joint comfort and flexibility with boswellia, turmeric curcuminoids and bromelain in one capsule.†\u003c\/li\u003e\n\u003cli\u003eSupports muscle comfort and recovery after hard exercise, with turmeric curcuminoids from Curcumin C3 Complex.†\u003c\/li\u003e\n\u003cli\u003eRounds out everyday joint support with 100 mg of quercetin plus devil's claw root, yucca root extract and alfalfa leaf in the same capsule.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cem\u003eBoswellia serrata\u003c\/em\u003e Extract\u003c\/td\u003e\n\u003ctd\u003e150 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBromelain (from pineapple, \u003cem\u003eAnanas comosus\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eQuercetin\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCurcumin C³ Complex®\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDevil's Claw Root (\u003cem\u003eHarpagophytum procumbens\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eYucca Root 4:1 Extract (\u003cem\u003eYucca\u003c\/em\u003e spp.)\u003c\/td\u003e\n\u003ctd\u003e25 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAlfalfa Leaf (\u003cem\u003eMedicago sativa\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e25 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 1 vegetarian capsule. The bottle holds 60 vegetarian capsules, so that's 60 one-capsule servings, or 30 days at one capsule twice daily. Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), deep mined calcium phosphate, cellulose, organic rice extract, and organic rice concentrate. The label states: \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" It also states: \"This product does not contain genetically modified materials.\" The label also notes that Curcumin C³ Complex® is a patented product of Sabinsa Corporation.\u003c\/p\u003e\n\u003ch2\u003eHow Inflameze works\u003c\/h2\u003e\n\u003cp\u003eStraight talk: we know of no clinical trial on Inflameze as a finished formula. The research below is on single ingredients, usually in other forms and amounts.\u003c\/p\u003e\n\u003ch3\u003eBoswellia serrata extract: 150 mg\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eBoswellia serrata\u003c\/em\u003e, sometimes called Indian frankincense, is a tree native to India, and boswellia extracts are usually made from its gum resin. Our label doesn't state a boswellic acid percentage, so we won't quote one or borrow results from studies of extracts standardized to specific levels.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15643550\/\"\u003ea crossover study in healthy men\u003c\/a\u003e, taking a boswellia extract with a high-fat meal raised blood levels of several boswellic acids several-fold compared with an empty stomach, and two of them only showed up at all with food. That study used a different extract at a much larger single dose (786 mg), but it's why we suggest taking Inflameze with a meal.\u003c\/p\u003e\n\u003ch3\u003eCurcumin C3 Complex: 50 mg of turmeric curcuminoids\u003c\/h3\u003e\n\u003cp\u003eTurmeric is the golden root in curry, and curcuminoids are the compounds behind that color. Per the label, Curcumin C3 Complex is a standardized extract of \u003cem\u003eCurcuma longa\u003c\/em\u003e with a minimum of 95% curcuminoids (curcumin, bisdemethoxy curcumin and demethoxy curcumin), so you know what's in each 50 mg.\u003c\/p\u003e\n\u003cp\u003eThe honest catch: curcumin on its own is poorly absorbed, quickly broken down and quickly cleared, as \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17999464\/\"\u003ea review of curcumin's bioavailability\u003c\/a\u003e lays out. Some formulas add piperine (black pepper extract) to help. Inflameze doesn't; the FAQ below points to the two Inflameze formulas that do.\u003c\/p\u003e\n\u003cp\u003eWhat the research shows: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37460208\/\"\u003ean umbrella review of meta-analyses of randomized trials\u003c\/a\u003e rated curcumin's effect on muscle soreness after muscle-damaging exercise as moderate-certainty evidence.† What it doesn't: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37408367\/\"\u003ea meta-analysis of 16 studies\u003c\/a\u003e found no statistically significant effect on post-exercise soreness, muscle damage markers or inflammation markers. Both reviews pooled trials that used various curcumin forms and doses, so read them as background, not a promise for 50 mg per capsule.\u003c\/p\u003e\n\u003ch3\u003eBromelain: 100 mg of pineapple enzymes\u003c\/h3\u003e\n\u003cp\u003eBromelain is a mix of protein-digesting enzymes from pineapple. Most proteins get broken down in the gut before absorption, but in \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9252520\/\"\u003ea study of 19 healthy men\u003c\/a\u003e, some bromelain reached the bloodstream intact and kept part of its enzyme activity. They took 3 grams a day, 15 times the 200 mg in two Inflameze capsules, so the study shows absorption happens, not how much you get at this dose.\u003c\/p\u003e\n\u003ch3\u003eQuercetin: 100 mg\u003c\/h3\u003e\n\u003cp\u003eQuercetin is a plant pigment found in apples, onions, capers and tea. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18716159\/\"\u003ea 2-week randomized trial in 35 healthy adults\u003c\/a\u003e taking 50, 100 or 150 mg a day, the 100 mg group's blood quercetin rose 359% from baseline. The same trial found no change in blood antioxidant capacity or inflammation markers, so we won't claim more than this: quercetin gets absorbed.\u003c\/p\u003e\n\u003ch3\u003eDevil's claw root, yucca root and alfalfa leaf\u003c\/h3\u003e\n\u003cp\u003eDevil's claw (\u003cem\u003eHarpagophytum procumbens\u003c\/em\u003e) is a southern African plant named for the hooked claws on its fruit. \"4:1 extract\" means four parts yucca root were concentrated into one part extract. Alfalfa leaf comes from the same plant farmers grow for hay. At 50 mg, 25 mg and 25 mg per capsule, these are supporting players, and we haven't found human research at these amounts we'd stand behind, so we make no specific claims for them.\u003c\/p\u003e\n\u003ch2\u003eHow to take Inflameze\u003c\/h2\u003e\n\u003cp\u003eThe label directions: \"One capsule twice daily. May take up to 4 capsules daily, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eOur suggestion: one with breakfast and one with dinner (see the boswellia food study above). If you go above two a day, stay at or under the label's 4-capsule maximum.\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. If you take prescription medication, including blood thinners, show your practitioner or pharmacist the Supplement Facts panel before you start.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cp\u003eWe've been making supplements in Oregon since 1974. Here's how each bottle earns its spot on your shelf.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, boswellia, turmeric extract, bromelain and the rest, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Inflameze has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps formulators, makers and testers under one roof, and the owners work in the building too. After 52 years of making supplements, we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many Inflameze capsules should I take a day?\u003c\/h3\u003e\n\u003cp\u003eOne capsule twice daily, per the label, which also allows up to 4 capsules a day. Two capsules give you 300 mg of boswellia extract, 200 mg each of bromelain and quercetin, and 100 mg of Curcumin C3 Complex. A 60-capsule bottle lasts 30 days at two a day.\u003c\/p\u003e\n\u003ch3\u003eShould I take Inflameze with food?\u003c\/h3\u003e\n\u003cp\u003eWe suggest it. The label doesn't require food, but boswellic acid levels were several-fold higher when boswellia was taken with a high-fat meal than on an empty stomach in the study above.\u003c\/p\u003e\n\u003ch3\u003eHow long before I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eThere's no set timeline, and we won't make one up. Take it steadily at the label's dose and judge it by how your normal week feels: the walk, the workout, the yard work.†\u003c\/p\u003e\n\u003ch3\u003eWhich Inflameze is right for me?\u003c\/h3\u003e\n\u003cp\u003eInflameze (this one) spreads each capsule across seven ingredients, led by boswellia, bromelain and quercetin. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/inflameze-advanced-turmeric-joint\"\u003eInflameze Advanced\u003c\/a\u003e is built around 250 mg of Curcumin Complex (from CurcuWIN™) per capsule, with a blend that includes boswellia standardized to 70% boswellic acids and Bioperine™. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/inflameze-ultra-caps-50ct\"\u003eInflameze Ultra\u003c\/a\u003e has 500 mg of Curcumin C3 Complex per 2-capsule serving, with ParActin® andrographis, organic ginger root and BioPerine®. If turmeric is your main interest, start with those two.\u003c\/p\u003e\n\u003ch3\u003eCan I take Inflameze with Joint Solution or the Joint + Mobility Stack?\u003c\/h3\u003e\n\u003cp\u003eYes, but count the overlap. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-support-structure-and-comfort\"\u003eJoint Solution\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-support-advanced\"\u003eJoint Solution Advanced\u003c\/a\u003e share many of the same botanicals; a full 4-capsule serving of Joint Solution Advanced adds 400 mg of boswellia extract, 200 mg each of bromelain and quercetin, and 100 mg of Curcumin C3 Complex. The \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-mobility-stack-inflameze-msm\"\u003eJoint + Mobility Stack\u003c\/a\u003e pairs Inflameze with MSM 2000 and Joint Solution Advanced, so that overlap is built in. Both Joint Solution labels state they contain glucosamine isolated from crab shell. Run any stack past your practitioner.\u003c\/p\u003e\n\u003ch3\u003eIs Inflameze safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, and bring the Supplement Facts panel so they can check each ingredient against your medication list.\u003c\/p\u003e\n\u003ch3\u003eIs Inflameze vegetarian?\u003c\/h3\u003e\n\u003cp\u003eYes. The label calls them vegetarian capsules, with a vegetable cellulose shell. The label doesn't make a vegan claim.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/why-choose-us\"\u003eHow we make and test our supplements\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/single-bottle-solution-what-is-it-and-why-do-we-put-it-on-our-premium-bottles\"\u003eWhat \"Single Bottle Solution\" on our bottles means\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eSterk V et al. Effect of food intake on the bioavailability of boswellic acids from a herbal preparation in healthy volunteers. Planta Med. 2004. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15643550\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAnand P et al. Bioavailability of curcumin: problems and promises. Mol Pharm. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17999464\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eTalebi S et al. Nutritional interventions for exercise-induced muscle damage: an umbrella review of systematic reviews and meta-analyses of randomized trials. Nutr Rev. 2024. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37460208\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eOxley RA, Peart DJ. The effect of curcumin supplementation on functional strength outcomes and markers of exercise-induced muscle damage: A systematic review and meta-analysis. Nutr Health. 2023. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37408367\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCastell JV et al. Intestinal absorption of undegraded proteins in men: presence of bromelain in plasma after oral intake. Am J Physiol. 1997. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9252520\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eEgert S et al. Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans. J Nutr. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18716159\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364426707226,"sku":"015-A1009","price":27.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A1009_REV00_Necktag.png?v=1753807599"},{"product_id":"joint-support-structure-and-comfort","title":"Joint Solution with Glucosamine – Joint Structure \u0026 Comfort | 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eJoint Solution is a daily joint supplement that pairs glucosamine with botanicals. Each 4-capsule serving has 750 mg glucosamine HCl, 250 mg glucosamine sulfate, 300 mg Boswellia serrata extract, 200 mg bromelain, 200 mg quercetin and 100 mg Curcumin C3 Complex®, plus devil's claw, alfalfa, collagen type II and yucca. Each bottle holds 60 capsules. It supports joint structure and joint comfort.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eJoint Solution is for people whose joints do a lot of work: runners, lifters, hikers, gardeners, and anyone who wants their knees and hips in good working order for the long haul. Glucosamine and collagen type II cover structure; boswellia, turmeric, bromelain and quercetin cover comfort.†\u003c\/p\u003e\n\u003cp\u003eYou don't have to wait for your 60s to look after your joints. If you're in your 30s or 40s and already training like you plan to stay busy for decades, this is an easy habit to add now. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Joint Solution\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports joint structure and joint comfort, the job printed right on the label.†\u003c\/li\u003e\n\u003cli\u003eSupplies glucosamine (750 mg HCl plus 250 mg sulfate per serving), a building block your body uses to make the cushioning molecules in cartilage.†\u003c\/li\u003e\n\u003cli\u003eSupports a healthy inflammatory response with Boswellia serrata, Curcumin C3 Complex®, bromelain and quercetin.†\u003c\/li\u003e\n\u003cli\u003eProvides antioxidant support from quercetin and turmeric curcuminoids.†\u003c\/li\u003e\n\u003cli\u003eAdds collagen type II, the main collagen in cartilage, with 20% chondroitin sulfate.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlucosamine HCl (from crab shell)\u003c\/td\u003e\n\u003ctd\u003e750 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlucosamine Sulfate (from 332 mg glucosamine sulfate KCl, from crab shell)\u003c\/td\u003e\n\u003ctd\u003e250 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cem\u003eBoswellia serrata\u003c\/em\u003e Extract\u003c\/td\u003e\n\u003ctd\u003e300 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBromelain (1200 GDU\/g, from \u003cem\u003eAnanas comosus\u003c\/em\u003e fruit)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eQuercetin\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCurcumin C³ Complex®\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDevil's Claw Root (\u003cem\u003eHarpagophytum procumbens\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAlfalfa Herb (\u003cem\u003eMedicago sativa\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCollagen Type II (contains 20% chondroitin sulfate)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eYucca Root 4:1 Extract (\u003cem\u003eYucca\u003c\/em\u003e spp.)\u003c\/td\u003e\n\u003ctd\u003e25 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 4 capsules. Servings per container: 15. Other ingredients: Gelatin (100% natural, preservative-free, from capsule shell), organic rice extract, and organic rice concentrate. The label states: \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" It also states: \"Contains Glucosamine, isolated from crab shell.\"\u003c\/p\u003e\n\u003ch2\u003eHow Joint Solution works\u003c\/h2\u003e\n\u003ch3\u003eGlucosamine: 750 mg HCl plus 250 mg sulfate\u003c\/h3\u003e\n\u003cp\u003eCartilage, the smooth tissue capping the ends of your bones, gets its cushion from long sugar chains called glycosaminoglycans, and glucosamine is one of their building blocks. Your body makes its own; a supplement supplies it ready-made.† The glucosamine here comes from crab shell in two forms: glucosamine HCl, and glucosamine sulfate supplied as glucosamine sulfate KCl (bound with potassium chloride), which is why the label lists 332 mg of glucosamine sulfate KCl to deliver 250 mg of glucosamine sulfate.\u003c\/p\u003e\n\u003cp\u003eFor healthy, active people, the closest research is a pair of studies in soccer players. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30132529\/\"\u003ea 16-week randomized, placebo-controlled trial in 43 college soccer players\u003c\/a\u003e, a supplement providing 2 g of glucosamine a day brought a urine marker of type II collagen breakdown below the placebo group's, while a collagen-building marker held steady, with no supplement-related side effects. An \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19724889\/\"\u003eearlier 3-month study of soccer players taking 1.5 or 3 g a day\u003c\/a\u003e saw the same drop, and saw it fade after they stopped. Two honest notes: these are lab markers in young athletes, not a measure of how joints feel, and the doses were higher than the 750 mg of glucosamine HCl plus 250 mg of glucosamine sulfate in a 4-capsule serving here.\u003c\/p\u003e\n\u003ch3\u003eBoswellia serrata extract: 300 mg\u003c\/h3\u003e\n\u003cp\u003eBoswellia serrata is the tree behind Indian frankincense, and its gum resin is a traditional Ayurvedic botanical. Its boswellic acids were long thought to work by blocking 5-lipoxygenase, an enzyme that makes signaling molecules in the body's inflammatory response.† \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21553931\/\"\u003eA review of the lab, animal and human data on boswellia\u003c\/a\u003e complicates that: the two most studied boswellic acids reach the blood at levels far below what blocks the enzyme in a test tube, while beta-boswellic acid reaches about 100 times higher levels and acts on other inflammation-related enzymes. Straight talk: exactly how boswellia works in people is still being sorted out.\u003c\/p\u003e\n\u003ch3\u003eCurcumin C3 Complex®: 100 mg\u003c\/h3\u003e\n\u003cp\u003eCurcumin C3 Complex® is a standardized turmeric root extract. The label specifies a minimum of 95% curcumin, bisdemethoxy curcumin and demethoxy curcumin (the curcuminoids), so each serving carries at least 95 mg. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29065496\/\"\u003eA review of curcumin's effects on human health\u003c\/a\u003e credits most of its studied effects to antioxidant activity and its role in the body's inflammatory response, including research in active people after hard exercise.† The same review names the catch: curcumin on its own is poorly absorbed and quickly cleared, and pairing it with piperine from black pepper raised absorption. Joint Solution doesn't include piperine, so turmeric is one contributor here, not the headline act.\u003c\/p\u003e\n\u003ch3\u003eQuercetin: 200 mg\u003c\/h3\u003e\n\u003cp\u003eQuercetin is a flavonoid, a plant pigment in onions, apples and tea, and in lab tests it acts as an antioxidant.† It does get absorbed. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18716159\/\"\u003ea 2-week randomized trial in 35 healthy adults\u003c\/a\u003e, 50 to 150 mg a day raised blood quercetin in step with the dose, by 178% to 570% over baseline. What it didn't show: any change in blood antioxidant capacity or an inflammation marker in those 2 weeks. Our 200 mg is above the trial's top dose, so its numbers don't map one-to-one.\u003c\/p\u003e\n\u003ch3\u003eBromelain: 200 mg (240 GDU)\u003c\/h3\u003e\n\u003cp\u003eBromelain is a group of protein-digesting enzymes from pineapple, measured by activity: the label lists 1200 GDU (gelatin digesting units) per gram, or 240 GDU per 4-capsule serving. We didn't find human research in healthy adults at this amount that we'd stand behind, so we don't cite any.\u003c\/p\u003e\n\u003ch3\u003eCollagen type II, devil's claw, alfalfa and yucca\u003c\/h3\u003e\n\u003cp\u003eType II collagen is the main collagen in cartilage, and chondroitin sulfate helps cartilage hold water.† The 50 mg here contains 20% chondroitin sulfate, or 10 mg. Devil's claw (\u003cem\u003eHarpagophytum procumbens\u003c\/em\u003e) is a southern African root and a traditional herb for joint comfort.† Alfalfa herb (\u003cem\u003eMedicago sativa\u003c\/em\u003e) is the leafy plant farmers grow for hay. Yucca root 4:1 extract is concentrated about 4 to 1, so its 25 mg stands in for roughly 100 mg of root. These four are supporting players, and we don't claim more for them.\u003c\/p\u003e\n\u003ch2\u003eHow to take Joint Solution\u003c\/h2\u003e\n\u003cp\u003eThe label directions: \"One to two capsules twice daily, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eThe amounts in the table are per serving, and the label's serving size is 4 capsules. The label doesn't mention food, so that part is up to you. Steady daily use is the idea, so tie your two daily doses to something you already do.\u003c\/p\u003e\n\u003cp\u003eIf you avoid shellfish, note the label statement: \"Contains Glucosamine, isolated from crab shell.\" Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cp\u003eWe've been making supplements in Oregon since 1974. And we're not getting old either. Here's what stands behind every lot of Joint Solution.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Joint Solution has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps formulators, makers and testers under one roof, and the owners work in the building too.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much glucosamine is in Joint Solution?\u003c\/h3\u003e\n\u003cp\u003eEach 4-capsule serving has 750 mg of glucosamine HCl and 250 mg of glucosamine sulfate, both from crab shell. The label directions are one to two capsules twice daily.\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eGive it a few months of steady daily use. The glucosamine studies above ran 3 to 4 months and measured lab markers, not how joints feel, so judge Joint Solution over months, not days.†\u003c\/p\u003e\n\u003ch3\u003eWhat's the difference between Joint Solution and Joint Solution Advanced?\u003c\/h3\u003e\n\u003cp\u003eJoint Solution Advanced adds MSM and hyaluronic acid. Both have 750 mg of glucosamine HCl and 250 mg of glucosamine sulfate per 4 capsules. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-support-advanced\"\u003eJoint Solution Advanced\u003c\/a\u003e adds 700 mg of MSM and 70 mg of hyaluronic acid, with 400 mg of Boswellia serrata extract instead of 300 mg, no yucca, and a vegetable cellulose capsule. Pick one, not both, since the glucosamine and botanicals overlap.\u003c\/p\u003e\n\u003ch3\u003eCan I take Joint Solution with Inflameze or MSM 2000?\u003c\/h3\u003e\n\u003cp\u003eMSM 2000 pairs without overlap; Inflameze doubles up. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/msm-2000mg-joint-health-support\"\u003eMSM 2000\u003c\/a\u003e is 2,000 mg of MSM in one tablet a day, an ingredient Joint Solution doesn't contain. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/inflameze-botanical-joint-support\"\u003eInflameze\u003c\/a\u003e has no glucosamine but repeats most of Joint Solution's botanicals, from boswellia to devil's claw, so we suggest choosing one. If you take medication, run any stack by your practitioner first.\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, especially if you take a blood thinner. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18363538\/\"\u003eA review of FDA and World Health Organization adverse-event reports\u003c\/a\u003e found cases where glucosamine taken with warfarin was linked to a higher INR, the blood test that tracks clotting time. Bring the label so they can check every ingredient.\u003c\/p\u003e\n\u003ch3\u003eIs Joint Solution vegetarian?\u003c\/h3\u003e\n\u003cp\u003eNo. The capsule shell is gelatin, the glucosamine comes from crab shell, and collagen type II is an animal protein.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eTsuruta A et al. Evaluation of the effect of the administration of a glucosamine-containing supplement on biomarkers for cartilage metabolism in soccer players: A randomized double-blind placebo-controlled study. Mol Med Rep. 2018. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30132529\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eYoshimura M et al. Evaluation of the effect of glucosamine administration on biomarkers for cartilage and bone metabolism in soccer players. Int J Mol Med. 2009. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19724889\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAbdel-Tawab M et al. Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data. Clin Pharmacokinet. 2011. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21553931\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHewlings SJ, Kalman DS. Curcumin: A Review of Its Effects on Human Health. Foods. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29065496\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eEgert S et al. Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans. J Nutr. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18716159\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKnudsen JF, Sokol GH. Potential glucosamine-warfarin interaction resulting in increased international normalized ratio: case report and review of the literature and MedWatch database. Pharmacotherapy. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18363538\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364426674458,"sku":"010-A1010","price":21.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A1010_REV00_Necktag.png?v=1738257571"},{"product_id":"joint-support-advanced","title":"Joint Solution Advanced with Hyaluronic Acid \u0026 MSM – Joint Comfort | 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eJoint Solution Advanced is a joint support supplement with 1,000 mg of glucosamine, 700 mg of MSM, 70 mg of hyaluronic acid and 50 mg of collagen type II in every 4-capsule serving, plus boswellia, bromelain, quercetin, Curcumin C³ Complex®, devil's claw and alfalfa. Each bottle holds 60 capsules (15 servings). It supports joint comfort and joint fluidity.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis one is for people who plan to keep moving: hikers, lifters, gardeners, weekend pickleball players. It builds on our original Joint Solution formula with 700 mg of MSM, 70 mg of hyaluronic acid and more boswellia, so the structural ingredients and the botanicals share one bottle.\u003c\/p\u003e\n\u003cp\u003eYou don't have to wait for your 60s to think about your joints. Start in your 30s and 40s, while you're still putting in the miles and the reps. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Joint Solution Advanced\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports joint comfort and joint fluidity, the two jobs printed on the label.†\u003c\/li\u003e\n\u003cli\u003eDelivers 1,000 mg of glucosamine, a building block your body uses to make cartilage, to support normal joint structure.†\u003c\/li\u003e\n\u003cli\u003eAdds 70 mg of hyaluronic acid, a natural part of the fluid that cushions your joints.†\u003c\/li\u003e\n\u003cli\u003eIncludes 700 mg of MSM, a sulfur compound studied in healthy, active men for post-workout recovery.†\u003c\/li\u003e\n\u003cli\u003eCovers joint structure and the botanicals in one daily routine: ten ingredients, one bottle.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal Glucosamine (from crab shell) (from 750 mg glucosamine HCl \u0026amp; 250 mg glucosamine sulfate)\u003c\/td\u003e\n\u003ctd\u003e1,000 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMSM (methyl sulfonyl methane)\u003c\/td\u003e\n\u003ctd\u003e700 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBoswellia serrata Extract\u003c\/td\u003e\n\u003ctd\u003e400 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBromelain (1200 GDU\/g, from Ananas comosus fruit)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eQuercetin\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCurcumin C³ Complex®\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDevil's Claw Root (Harpagophytum procumbens)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAlfalfa Herb (Medicago sativa)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHyaluronic Acid\u003c\/td\u003e\n\u003ctd\u003e70 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCollagen Type II (contains 20% chondroitin sulfate)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 4 capsules. Servings per container: 15. Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), organic rice concentrate, and organic rice extract. The label states: \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" It also states: \"Contains Glucosamine, isolated from crab shell.\"\u003c\/p\u003e\n\u003ch2\u003eHow Joint Solution Advanced works\u003c\/h2\u003e\n\u003ch3\u003eGlucosamine: 1,000 mg from crab shell\u003c\/h3\u003e\n\u003cp\u003eGlucosamine is an amino sugar your body makes and uses to build the long molecules that give cartilage its bounce. Here it's isolated from crab shell, in two common forms: 750 mg of glucosamine HCl and 250 mg of glucosamine sulfate.\u003c\/p\u003e\n\u003cp\u003eWhat the research shows: in \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30132529\/\"\u003ea 16-week randomized, placebo-controlled trial in 43 college soccer players\u003c\/a\u003e, a supplement providing 2 grams of glucosamine a day lowered a urine marker of type II collagen breakdown (type II is the main collagen in cartilage) below the placebo group, while a collagen-building marker held steady, with no supplement-related side effects. What it doesn't show: these were lab markers in young athletes, not how anyone's knees felt, at twice the glucosamine in one serving here.\u003c\/p\u003e\n\u003ch3\u003eHyaluronic acid (70 mg) and collagen type II (50 mg)\u003c\/h3\u003e\n\u003cp\u003eHyaluronic acid is a long sugar chain your body makes to hold water, and it's what makes the fluid inside your joints slick and cushiony. It's here to support joint fluidity.† \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27982756\/\"\u003eA study of orally given hyaluronan in rats\u003c\/a\u003e found gut bacteria break it into smaller pieces that are absorbed in the large intestine and reach tissues such as skin. That's animal data, and it shows absorption, not anything about joints.\u003c\/p\u003e\n\u003cp\u003eThe 50 mg of collagen type II contains 20% chondroitin sulfate, about 10 mg of chondroitin. That's not much, so we don't call this a chondroitin supplement.\u003c\/p\u003e\n\u003ch3\u003eMSM: 700 mg\u003c\/h3\u003e\n\u003cp\u003eMSM (methylsulfonylmethane) is a sulfur compound found in small amounts in many foods. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28300758\/\"\u003eA review of MSM's uses and safety\u003c\/a\u003e notes it is Generally Recognized As Safe (GRAS) and well tolerated by most people at up to 4 grams a day, with few, mild side effects.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23013531\/\"\u003ea 30-day pilot study in 8 healthy, moderately active men\u003c\/a\u003e taking 1.5 or 3 grams a day, soreness after a hard leg workout trended lower on the higher dose, and blood antioxidant capacity rose after exercise at 3 grams.† Straight talk: 8 people, trends rather than firm results, at doses at least twice our 700 mg. For more MSM, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/msm-2000mg-joint-health-support\"\u003eMSM 2000 has 2,000 mg in one tablet\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eBoswellia, Curcumin C³ Complex® and devil's claw\u003c\/h3\u003e\n\u003cp\u003eBoswellia serrata extract (400 mg) comes from a tree resin also called Indian frankincense, best known for its boswellic acids. Devil's claw (100 mg) is a root from southern Africa. Curcumin C³ Complex® (100 mg) is a turmeric extract that, per the label, is at least 95% curcuminoids.\u003c\/p\u003e\n\u003cp\u003eOne honest limit: curcumin on its own is poorly absorbed and quickly cleared, as \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17999464\/\"\u003ea review of curcumin bioavailability\u003c\/a\u003e lays out, and this formula has no absorption helper like black pepper extract, so think of it as a supporting amount. The label doesn't list a standardization for the boswellia or devil's claw, so we don't borrow results from studies of branded extracts.\u003c\/p\u003e\n\u003ch3\u003eBromelain, quercetin and alfalfa\u003c\/h3\u003e\n\u003cp\u003eBromelain is a group of protein-digesting enzymes from pineapple: 200 mg at 1200 GDU\/g (a measure of enzyme activity). In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9252520\/\"\u003ea study of bromelain absorption in 19 healthy men\u003c\/a\u003e, a small amount of intact bromelain reached the blood after it was taken by mouth and kept at least part of its enzyme activity. Its repeat-dose phase used 3 grams a day, many times our 200 mg, and measured absorption, not joints. Quercetin (200 mg) is a plant flavonoid studied for its antioxidant activity, and alfalfa herb (100 mg) is the above-ground part of the alfalfa plant. We don't make separate claims for these supporting players.\u003c\/p\u003e\n\u003ch2\u003eHow to take Joint Solution Advanced\u003c\/h2\u003e\n\u003cp\u003eThe label says: \"One to two capsules twice daily, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eThe amounts in the table are for the label's 4-capsule serving. The label doesn't name a time of day or mention food; breakfast and dinner make both doses easy to remember.\u003c\/p\u003e\n\u003cp\u003eIf you avoid shellfish, skip this one: the glucosamine is isolated from crab shell.\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, from the crab-shell glucosamine to the devil's claw root, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Joint Solution Advanced has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility there keeps formulators, makers and testers under one roof. The owners work in the building too, and the company has been owner-run since 2017. We've been making supplements in Oregon since 1974. We're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many capsules of Joint Solution Advanced do I take a day?\u003c\/h3\u003e\n\u003cp\u003eThe label says one to two capsules twice daily. The Supplement Facts serving size is 4 capsules, which provides 1,000 mg of glucosamine, 700 mg of MSM and 70 mg of hyaluronic acid.\u003c\/p\u003e\n\u003ch3\u003eHow many servings are in a bottle?\u003c\/h3\u003e\n\u003cp\u003eThe label lists 15 servings of 4 capsules in each 60-capsule bottle.\u003c\/p\u003e\n\u003ch3\u003eHow is it different from the original Joint Solution?\u003c\/h3\u003e\n\u003cp\u003eAdvanced adds 700 mg of MSM and 70 mg of hyaluronic acid and has 400 mg of boswellia instead of 300 mg. Both list 750 mg of glucosamine HCl, 250 mg of glucosamine sulfate, 50 mg of collagen type II, and the same amounts of bromelain, quercetin, Curcumin C³ Complex®, devil's claw and alfalfa. The original adds 25 mg of yucca root extract and uses a gelatin capsule; Advanced uses vegetable cellulose. For the simpler formula, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-support-structure-and-comfort\"\u003esee the original Joint Solution\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eIs Joint Solution Advanced vegetarian or shellfish-free?\u003c\/h3\u003e\n\u003cp\u003eNo to both. The glucosamine is isolated from crab shell, and collagen is an animal protein, even though the capsule shell is vegetable cellulose.\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice anything?\u003c\/h3\u003e\n\u003cp\u003eThere's no set timeline; neither the label nor the research cited above gives one. The glucosamine trial ran 16 weeks and measured lab markers, not how joints feel, so give it a few months of steady use before you judge it.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Inflameze or MSM 2000?\u003c\/h3\u003e\n\u003cp\u003eYes, they're sold together in our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-mobility-stack-inflameze-msm\"\u003eJoint + Mobility Stack\u003c\/a\u003e, but know your totals. One MSM 2000 tablet plus a 4-capsule serving here is 2,700 mg of MSM a day, within the up-to-4-gram range the safety review above calls well tolerated by most people. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/inflameze-botanical-joint-support\"\u003eInflameze\u003c\/a\u003e repeats several botanicals from this formula (boswellia, bromelain, quercetin, Curcumin C³ Complex®, devil's claw and alfalfa), so follow each label.\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner before you start, and bring the bottle so they can see the full ingredient list.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-support-structure-and-comfort\"\u003eThe original Joint Solution formula, without MSM or hyaluronic acid\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/msm-2000mg-joint-health-support\"\u003eMSM 2000, with 2,000 mg of MSM per tablet\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-mobility-stack-inflameze-msm\"\u003eThe Joint + Mobility Stack: this formula, Inflameze and MSM 2000\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eTsuruta A et al. Evaluation of the effect of the administration of a glucosamine‑containing supplement on biomarkers for cartilage metabolism in soccer players: A randomized double‑blind placebo‑controlled study. Mol Med Rep. 2018. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30132529\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKimura M et al. Absorption of Orally Administered Hyaluronan. J Med Food. 2016. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27982756\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eButawan M et al. Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28300758\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKalman DS et al. Influence of methylsulfonylmethane on markers of exercise recovery and performance in healthy men: a pilot study. J Int Soc Sports Nutr. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23013531\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAnand P et al. Bioavailability of curcumin: problems and promises. Mol Pharm. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17999464\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCastell JV et al. Intestinal absorption of undegraded proteins in men: presence of bromelain in plasma after oral intake. Am J Physiol. 1997. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9252520\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364426641690,"sku":"015-A1011","price":25.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A1011_REV00_Necktag.png?v=1738257599"},{"product_id":"water-away-bloating-fluid-support","title":"Water-Away – Herbal Fluid Balance Support | 60 Vegetarian Tablets","description":"\u003cp\u003e\u003cstrong\u003eWater-Away is an herbal fluid balance formula in 60 vegetarian tablets. Each one-tablet serving combines 120 mg uva ursi leaf 4:1 extract, 60 mg juniper berry 20:1 extract, 30 mg buchu leaf 4:1 extract, 30 mg black radish root, 30 mg parsley leaf, 20 mg asparagus root 5:1 extract and 33 mg potassium from potassium chloride, to support the body's normal fluid balance.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWater-Away is for the days you feel puffy and heavy: the salty restaurant dinner, the long flight, the hot week, the stretch before your period. It puts six herbs, several with a long history of use for supporting urine flow, plus a little potassium, into one tablet you take before a meal.†\u003c\/p\u003e\n\u003cp\u003eHere's the candid part. These herbs have a long traditional track record, and there's lab and animal research on how some of them work. Nobody has run a human trial on this exact formula, though, and human research on these herbs for fluid balance is thin. Below is what's known and what isn't.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Water-Away\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNormal fluid balance.\u003c\/strong\u003e The whole formula is built around one job: supporting the way your body normally manages water.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUrinary tract function.\u003c\/strong\u003e Uva ursi, juniper and buchu are classic herbs traditionally used to support normal urine flow and urinary tract health.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA small electrolyte assist.\u003c\/strong\u003e Each tablet adds 33 mg of potassium, the electrolyte that manages fluid inside your cells. It's a supporting player, not a headliner.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMade for occasional puffy days.\u003c\/strong\u003e Take it around the salty dinner, the travel day or the heat wave, when water weight and that bloated feeling tend to show up.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSix herbs, one tablet.\u003c\/strong\u003e That's what \"Single Bottle Solution\" on the label means: one formula, not a shelf of single-herb bottles.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePotassium (from 63 mg potassium chloride - electrolytes)\u003c\/td\u003e\n\u003ctd\u003e33 mg\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;1%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUva Ursi Leaf 4:1 Extract (\u003cem\u003eArctostaphylos uva ursi\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e120 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eJuniper Berry 20:1 Extract (\u003cem\u003eJuniperus communis\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e60 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBuchu Leaf 4:1 Extract (\u003cem\u003eAgathosma betulina\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e30 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBlack Radish Root (\u003cem\u003eRaphanus sativus\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e30 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParsley Leaf (\u003cem\u003ePetroselinum crispum\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e30 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAsparagus Root 5:1 Extract (\u003cem\u003eAsparagus cochinchinensis\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e20 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established. Serving size: 1 Vegetarian Tablet. The bottle holds 60 vegetarian tablets, so it contains 60 one-tablet servings. Other ingredients, as printed on the label: \"Vegetable cellulose (preservative-free, from capsule shell), organic rice extract, cellulose, and organic rice concentrate.\"\u003c\/p\u003e\n\u003ch2\u003eHow Water-Away works\u003c\/h2\u003e\n\u003cp\u003eYour kidneys run the water budget. They decide how much sodium, potassium and water to keep and how much to send out. Sodium mostly governs the fluid outside your cells and potassium the fluid inside them, as the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Potassium-HealthProfessional\/\"\u003eNIH fact sheet on potassium\u003c\/a\u003e explains. After a salty meal, your body hangs on to extra water to keep sodium in balance, which can leave you feeling puffy. Several of the herbs in Water-Away, led by uva ursi, juniper, buchu and parsley, are ones people have traditionally used to support normal urine flow.†\u003c\/p\u003e\n\u003ch3\u003eUva ursi leaf (120 mg, 4:1 extract)\u003c\/h3\u003e\n\u003cp\u003eUva ursi is bearberry, a low evergreen shrub whose leaves have a long history in European herbal practice for urinary support. Its main compound is arbutin. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12162475\/\"\u003ea randomized crossover study in 16 healthy volunteers\u003c\/a\u003e, about 65% of the arbutin from a single dose of bearberry leaf extract came out in urine as hydroquinone compounds, peaking roughly 3.6 to 4.4 hours after the dose. That's how uva ursi's compounds reach the urinary tract. What the study didn't measure is fluid balance or how anyone felt.\u003c\/p\u003e\n\u003ch3\u003eJuniper berry (60 mg, 20:1 extract)\u003c\/h3\u003e\n\u003cp\u003eYes, the same berry that flavors gin. Juniper has a long run in European herbal tradition for supporting urine flow, and this is a concentrated 20:1 extract. Straight talk: human trials on juniper and fluid balance are missing, and \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17804183\/\"\u003ea 2007 review of herbs studied for urine output\u003c\/a\u003e did not name juniper, uva ursi or buchu among its most promising plants.\u003c\/p\u003e\n\u003ch3\u003eBuchu leaf (30 mg, 4:1 extract)\u003c\/h3\u003e\n\u003cp\u003eBuchu is a South African shrub whose aromatic leaf oil also shows up in flavors and fragrances. It was a popular remedy in the United States in the 1800s. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35197854\/\"\u003eA 2022 review of buchu research\u003c\/a\u003e found the modern pharmacology work scarce, mostly cell and animal studies, and said health claims need randomized, placebo-controlled human trials. Buchu earns its spot through tradition, not clinical data.\u003c\/p\u003e\n\u003ch3\u003eParsley leaf (30 mg)\u003c\/h3\u003e\n\u003cp\u003eParsley's effect on urine output has been studied directly, though not in people. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11849841\/\"\u003ea rat study of parsley extract\u003c\/a\u003e, rats drinking a parsley seed extract made more urine over 24 hours. The researchers traced it to a slower sodium-potassium pump in the kidney: less sodium pulled back into the body, so more water follows it out. The 2007 review listed parsley among the more promising herbs while noting the number of studies is limited. Two honest caveats: those rats got seed extract, and our 30 mg is leaf.\u003c\/p\u003e\n\u003ch3\u003eBlack radish root (30 mg) and asparagus root (20 mg, 5:1 extract)\u003c\/h3\u003e\n\u003cp\u003eBlack radish is a cruciferous root, a cousin of cabbage and broccoli. Its signature compounds are glucosinolates, and \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21640355\/\"\u003ea lab analysis of black radish supplements\u003c\/a\u003e identified six different ones. The asparagus root here is \u003cem\u003eAsparagus cochinchinensis\u003c\/em\u003e, Chinese asparagus, a long-standing herb in traditional Chinese practice. For both, human research on fluid balance is lacking.\u003c\/p\u003e\n\u003ch3\u003ePotassium (33 mg from potassium chloride)\u003c\/h3\u003e\n\u003cp\u003ePotassium is the main electrolyte inside your cells and works opposite sodium. Honest math: 33 mg is less than 1% of the Daily Value. The \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Potassium-HealthProfessional\/\"\u003eNIH adequate intake for potassium\u003c\/a\u003e is 2,600 mg a day for adult women and 3,400 mg for men, and foods like lentils, beans, potatoes, bananas and spinach are good sources. The potassium here rounds out the formula; it isn't a way to meet your daily needs.†\u003c\/p\u003e\n\u003ch2\u003eHow to take Water-Away\u003c\/h2\u003e\n\u003cp\u003eThe label says: \"One to three tablets with a glass of water before a meal, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eStarting with one tablet lets you see how you do before moving up within the label's range. If you notice more bathroom trips, take it before breakfast or lunch rather than dinner.\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. That goes double if you take a prescription water pill, blood pressure medicine, or anything else that affects your fluid or potassium levels.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, from the uva ursi to the potassium chloride, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Water-Away gets one, so the numbers on the label have paperwork behind them.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e That's a farm town of about 3,500 people in the Willamette Valley, where our formulators, makers and testers work under one roof in a UL-certified cGMP facility. The owners work in the building too, and the company has been owner-run since 2017. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many Water-Away tablets should I take?\u003c\/h3\u003e\n\u003cp\u003eThe label says one to three tablets with a glass of water before a meal. The Supplement Facts amounts are per tablet, so two tablets double every number in the table.\u003c\/p\u003e\n\u003ch3\u003eHow soon will I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eWe can't give you a reliable timeline, because no one has studied this exact formula in people. In healthy volunteers, the breakdown products of uva ursi's arbutin peaked in urine about 3.6 to 4.4 hours after \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12162475\/\"\u003ea single dose of bearberry leaf extract\u003c\/a\u003e. That tells you how fast the body processes it, not how you'll feel.\u003c\/p\u003e\n\u003ch3\u003eIs Water-Away a water pill?\u003c\/h3\u003e\n\u003cp\u003eNo. It's a dietary supplement made to support normal fluid balance, not a drug.† If you've been prescribed a diuretic, keep taking it as directed and talk with your prescriber before adding Water-Away. Sudden, painful or lasting swelling is a reason to see your doctor.\u003c\/p\u003e\n\u003ch3\u003eWhat do 4:1, 5:1 and 20:1 mean on the label?\u003c\/h3\u003e\n\u003cp\u003eThey're extract ratios: roughly how many parts of dried plant went into one part of extract. A 4:1 uva ursi extract started with about four parts leaf for every part of finished extract, and a 20:1 juniper extract with about twenty parts berry. Ratios tell you about concentration. They don't tell you the amount of any single compound.\u003c\/p\u003e\n\u003ch3\u003eDoes Water-Away add much potassium to my day?\u003c\/h3\u003e\n\u003cp\u003eNot much. Each tablet adds 33 mg of potassium, less than 1% of the Daily Value, which is small next to food or a separate potassium supplement. If you take medicine that affects potassium or fluid, ask your healthcare practitioner first.\u003c\/p\u003e\n\u003ch3\u003eIs Water-Away vegetarian?\u003c\/h3\u003e\n\u003cp\u003eYes. The label lists each serving as \"1 Vegetarian Tablet,\" and the bottle holds 60 vegetarian tablets.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/single-bottle-solution-what-is-it-and-why-do-we-put-it-on-our-premium-bottles\"\u003eWhat \"Single Bottle Solution\" on our bottles means\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/our-approach-to-raw-material-sourcing-and-testing\"\u003eHow we source and test raw materials\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/why-choose-us\"\u003eWhy people choose Mt. Angel Vitamins\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium, our amino acid chelated magnesium\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/livr-support-liver-detox-cleanse\"\u003eLIV'R Support, our liver support formula with milk thistle\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eSchindler G et al. Urinary excretion and metabolism of arbutin after oral administration of Arctostaphylos uvae ursi extract as film-coated tablets and aqueous solution in healthy humans. J Clin Pharmacol. 2002. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12162475\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWright CI et al. Herbal medicines as diuretics: a review of the scientific evidence. J Ethnopharmacol. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17804183\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBrendler T et al. Buchu (Agathosma betulina and A. crenulata): Rightfully Forgotten or Underutilized? Front Pharmacol. 2022. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35197854\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKreydiyyeh SI et al. Diuretic effect and mechanism of action of parsley. J Ethnopharmacol. 2002. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11849841\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eEdiage EN et al. Screening, identification and quantification of glucosinolates in black radish (Raphanus sativus L. niger) based dietary supplements using liquid chromatography coupled with a photodiode array and liquid chromatography-mass spectrometry. J Chromatogr A. 2011. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21640355\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364426084634,"sku":"015-A1022","price":19.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A1022REV00_ListingImage1.png?v=1738965591"},{"product_id":"betaine-hcl-stomach-digestion","title":"Betaine HCl 649 mg – Stomach Acid \u0026 Protein Digestion Support | 100-500 Capsules","description":"\u003cp\u003e\u003cstrong\u003eBetaine HCl (labeled Hydrochloric Acid Betaine) gives you 10 grains (649 mg) of betaine HCl plus 2 grains (130 mg) of acid-stable protease in each vegetarian capsule, in bottles of 100, 200 or 500. Taken with meals, it is a supplemental source of hydrochloric acid that supports healthy levels of gastric juices and the breakdown of dietary protein.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis one is for adults who want some help on the stomach side of digestion, especially at meals built around protein: steak, fish, eggs, beans, the holiday plate you went back to twice. Digestion of protein starts in the stomach, where acid and the enzyme pepsin begin taking food apart before the small intestine finishes the job. Betaine HCl puts extra acid, plus an enzyme that works in acid, right where that first step happens.†\u003c\/p\u003e\n\u003cp\u003eIt is acidic on purpose, so it is not a casual add-on. If you take medication or have a medical condition, talk with your healthcare practitioner before you start, then begin with one capsule at a meal, the low end of the label's directions.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Betaine HCl\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy levels of gastric juices when taken with or right after a meal.†\u003c\/li\u003e\n\u003cli\u003eSupplies hydrochloric acid, the same acid your stomach makes to help digest protein.†\u003c\/li\u003e\n\u003cli\u003eAdds 130 mg of acid-stable protease, an enzyme that stays active in stomach acid and helps break down dietary protein.†\u003c\/li\u003e\n\u003cli\u003eSupports the absorption of vitamins and minerals from food, since stomach acid helps your body take up iron, calcium and vitamin B12.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eBetaine HCl\u003c\/td\u003e\n\u003ctd\u003e10 grains (649 mg)\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAcid Stable Protease 500 SAPU\/g\u003c\/td\u003e\n\u003ctd\u003e2 grains (130 mg)\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established.\u003c\/p\u003e\n\u003cp\u003eServing size is 1 Vegetarian ChloroCap™, and bottles come in 100, 200 or 500 capsules. Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), cellulose, silica, magnesium stearate, and chlorophyll. The label states: \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" The chlorophyll is why the capsules are green.\u003c\/p\u003e\n\u003ch2\u003eHow Betaine HCl works\u003c\/h2\u003e\n\u003ch3\u003eBetaine HCl: hydrochloric acid in a dry, swallowable form\u003c\/h3\u003e\n\u003cp\u003eYou can't put liquid hydrochloric acid in a capsule. Betaine HCl solves that: it is betaine (also called trimethylglycine) bonded to hydrochloric acid as a dry, crystalline salt. When the capsule opens in your stomach, it dissolves and releases its acid into the meal you just ate. Once things move on to the small intestine, which is alkaline, the label explains that it transforms into plain betaine.†\u003c\/p\u003e\n\u003cp\u003eThe label lists the dose in grains, an old apothecary unit (one grain is about 65 mg), and prints the milligrams right beside it: 649 mg of betaine HCl and 130 mg of protease.\u003c\/p\u003e\n\u003cp\u003eWhy acid matters at all: stomach acid helps you digest protein, and it helps your body absorb iron, calcium and vitamin B12 from food. It also affects how certain medications are absorbed, which is one reason to check with your practitioner before adding an acid supplement (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25211241\/\"\u003ea review of how the stomach regulates acid\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eA quick note on food: betaine HCl itself is not something you get from food, but plain betaine is. Rich sources include wheat germ or bran, spinach and seafood, and in the body betaine works as an osmolyte (it helps cells hold their water balance) and as a methyl donor (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15321791\/\"\u003ea review of betaine in human nutrition\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eNow the candid part. Direct human research on betaine HCl is thin: a handful of small, short studies, mostly from drug-absorption research, and no large trials testing it as an everyday digestive supplement in healthy people. The physiology of stomach acid is well established. How much a betaine HCl capsule adds for any one person is much less studied, which is why we keep the claims modest and point you to your practitioner.\u003c\/p\u003e\n\u003ch3\u003eAcid Stable Protease: an enzyme built to work in the stomach\u003c\/h3\u003e\n\u003cp\u003eProteases are enzymes that cut proteins into smaller pieces your body can absorb. Plenty of enzymes lose steam in strong acid. An acid-stable protease is chosen because it keeps working at stomach pH, so it can start on protein alongside your own pepsin.† The \"500 SAPU\/g\" on the label measures its activity: SAPU stands for spectrophotometric acid protease units. Each capsule has 130 mg of protease at that strength.\u003c\/p\u003e\n\u003cp\u003eWhy the stomach stage matters: the meeting between protein and pepsin in the stomach is the first step of protein breakdown, and how fast it goes depends on the type of protein and how the food was cooked or processed (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39836113\/\"\u003ea review of pepsin and food protein digestion\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eWhat the research on added proteases shows: in a small open-label study, healthy men who took 50 g of whey protein with 2.5 g or 5 g of a fungal protease blend had higher blood amino acid levels over the next four hours than when they took the same whey alone (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18652668\/\"\u003ean open-label protease and whey protein study in healthy men\u003c\/a\u003e). Keep the limits in view: it used a different enzyme blend at a far larger amount than the 130 mg here, everyone knew what they were taking, and one author worked for an ingredient company. It supports the idea, not this specific capsule.\u003c\/p\u003e\n\u003ch2\u003eHow to take Betaine HCl\u003c\/h2\u003e\n\u003cp\u003eLabel directions: \"One to two capsules with or immediately following a meal, as a dietary supplement. As a supplemental source of hydrochloric acid, best taken with a small amount of water.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTake it with a meal or right after one, as the directions say, not on an empty stomach.\u003c\/li\u003e\n\u003cli\u003eIf you also take \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/super-enzymes-plus\"\u003eSuper Enzymes+ digestive enzymes\u003c\/a\u003e, note that its label lists 150 mg of betaine HCl per capsule. Count both when you add up your total.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming ingredient lot, including the betaine HCl and protease in this bottle, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Each lot of this product gets its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e That's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility is where this product is made and tested, with formulators, makers and testers all under one roof. The owners work in the building too, and have run the company since 2017, so when something needs a decision, it gets made down the hall. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much betaine HCl is in each capsule?\u003c\/h3\u003e\n\u003cp\u003eEach capsule has 10 grains (649 mg) of betaine HCl, plus 2 grains (130 mg) of acid-stable protease. The label's serving is one capsule, and the directions say one to two capsules with or immediately following a meal.\u003c\/p\u003e\n\u003ch3\u003eWhen should I take Betaine HCl?\u003c\/h3\u003e\n\u003cp\u003eTake it with a meal or right after one, with a small amount of water. It is meant to work alongside a meal, so skip it on an empty stomach.\u003c\/p\u003e\n\u003ch3\u003eIs betaine HCl the same as betaine or TMG?\u003c\/h3\u003e\n\u003cp\u003eNo. Both contain betaine, but betaine HCl carries hydrochloric acid and plain betaine (often sold as TMG or betaine anhydrous) does not. People take betaine HCl for the acid at mealtime; TMG is taken for betaine itself.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Super Enzymes+?\u003c\/h3\u003e\n\u003cp\u003eCheck with your practitioner first, and count the betaine HCl in both. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/super-enzymes-plus\"\u003eSuper Enzymes+\u003c\/a\u003e lists 150 mg of betaine HCl per capsule alongside its pancreatic enzyme complex, so the combined amount at a meal adds up.\u003c\/p\u003e\n\u003ch3\u003eDoes stomach acid drop as you get older?\u003c\/h3\u003e\n\u003cp\u003eNot automatically. In a study of 248 adults aged 65 and older who lived independently, nearly 90% could acidify their stomach contents even without a meal to trigger it (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9272898\/\"\u003ea study of stomach acidity in older adults\u003c\/a\u003e). So age alone isn't a reason to take betaine HCl; your practitioner can help you decide if it fits.\u003c\/p\u003e\n\u003ch3\u003eIs it safe with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first. Stomach acid affects how some medications are absorbed, and an acid supplement changes that picture, so this is a conversation to have before your first capsule, not after.\u003c\/p\u003e\n\u003ch3\u003eHow soon will I notice anything?\u003c\/h3\u003e\n\u003cp\u003eIt is designed to work at the meal you take it with, not to build up over weeks.† There's no research that sets a timeline for this product, so talk with your practitioner about what to expect.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/super-enzymes-plus\"\u003eSuper Enzymes+, a pancreatic enzyme blend for fats, proteins and carbs\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/3-in-1-probiotic-fusion\"\u003e3-in-1 Probiotic Fusion, a prebiotic, probiotic and postbiotic capsule\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/digestive\/digestive-health-and-the-gut-microbiome\"\u003eAn introduction to the gut microbiome and digestive health\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/our-approach-to-raw-material-sourcing-and-testing\"\u003eHow we source and test raw materials before they reach a bottle\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eSchubert ML. Gastric secretion. Current opinion in gastroenterology. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25211241\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCraig SA. Betaine in human nutrition. The American journal of clinical nutrition. 2004. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15321791\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eYang M et al. Digestion of food proteins: the role of pepsin. Critical reviews in food science and nutrition. 2025. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39836113\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eOben J et al. An open label study to determine the effects of an oral proteolytic enzyme system on whey protein concentrate metabolism in healthy males. Journal of the International Society of Sports Nutrition. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18652668\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHurwitz A et al. Gastric acidity in older adults. JAMA. 1997. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9272898\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"100","offer_id":44398243315994,"sku":"010-A3000","price":29.99,"currency_code":"USD","in_stock":true},{"title":"200","offer_id":44364428050714,"sku":"010-A3001","price":47.99,"currency_code":"USD","in_stock":true},{"title":"500","offer_id":44364428083482,"sku":"010-A3009","price":91.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A3009_REV05_Listing_Image_1.png?v=1738257722"},{"product_id":"super-enzymes-plus","title":"Super Enzymes+ – Fat, Protein and Carb Digestion Support | 100 or 200 Capsules","description":"\u003cp\u003e\u003cstrong\u003eSuper Enzymes+ is a fat digesting enzyme formula in capsules, sold in 100- and 200-capsule bottles. Each capsule pairs a 240 mg delayed-release pancreatic enzyme complex (17,400 USP amylase, 3,200 USP lipase and 15,400 USP protease units) with 150 mg betaine HCl, 75 mg ox bile, 50 mg acid stable protease and 13 mg papain to support the digestion of fats, proteins and starches at mealtime.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIf a rich dinner or a big restaurant meal tends to sit with you longer than it used to, this formula was built for that plate. Your body already makes its own enzymes, bile and stomach acid. Super Enzymes+ brings more of each kind to the table, so the work of breaking food down has some backup.† It's for adults who eat real meals and would rather support digestion than give up the steak.\u003c\/p\u003e\n\u003cp\u003eWe've been making supplements in Oregon since 1974, and we'd rather explain a formula than hype it. So here's every ingredient, and what the research does and doesn't show.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Super Enzymes+\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFat digestion.\u003c\/strong\u003e 3,200 USP lipase units plus 75 mg of ox bile per capsule support the breakdown of dietary fats.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtein digestion from three directions.\u003c\/strong\u003e Pancreatic protease (15,400 USP units), acid stable protease and papain support protein breakdown.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStarch digestion.\u003c\/strong\u003e 17,400 USP amylase units from the pancreatic enzyme complex support the breakdown of starches.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStomach-stage support.\u003c\/strong\u003e 150 mg of betaine HCl, a source of hydrochloric acid, supports the acidic stomach environment where protein digestion begins.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRelease timed to where the enzymes work.\u003c\/strong\u003e The pancreatic enzyme complex is delayed release, made to pass the stomach and work where your own pancreatic enzymes do.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePancreatic Enzyme Complex (delayed release) (contains pancrelipase, pancreatin, and diastase; contains 17,400 USP amylase units; 3,200 USP lipase units; 15,400 USP protease units)\u003c\/td\u003e\n\u003ctd\u003e240 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBetaine HCl\u003c\/td\u003e\n\u003ctd\u003e150 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFenugreek Seed (\u003cem\u003eTrigonella foenum-graecum\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOx Bile\u003c\/td\u003e\n\u003ctd\u003e75 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAcid Stable Protease 500 SAPU\/g\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePapain (contains 75,000 USP papain units)\u003c\/td\u003e\n\u003ctd\u003e13 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eProprietary Blend\u003cbr\u003eContains: Choline Bitartrate, Inositol, Hops Strobiles, Peppermint Leaf, Chamomile Flower, and Yarrow Flower\u003c\/td\u003e\n\u003ctd\u003e32 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established. Serving size is 1 capsule. The panel doesn't print a servings-per-container number, so count capsules: one capsule is one serving. Other ingredients, as printed: \"Deep mined calcium phosphate, gelatin (100% natural, preservative-free, from capsule shell), magnesium trisilicate, magnesium stearate, silica, and stabilized rice bran.\" The label states: \"NO soy, salt, yeast, gluten, egg products, sugar, starch, or preservatives.\" It is not vegetarian.\u003c\/p\u003e\n\u003ch2\u003eHow Super Enzymes+ works\u003c\/h2\u003e\n\u003cp\u003eDigestion is a relay. Stomach acid and pepsin, the stomach's own enzyme, start on protein. Then the pancreas sends proteases, lipases and amylases into the small intestine to break complex nutrients into pieces small enough to absorb (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17205399\/\"\u003eWhitcomb and Lowe review of human pancreatic enzymes\u003c\/a\u003e), and bile arrives to help with fat. Super Enzymes+ puts something in each leg of that relay.†\u003c\/p\u003e\n\u003ch3\u003ePancreatic Enzyme Complex (240 mg, delayed release)\u003c\/h3\u003e\n\u003cp\u003ePancreatin and pancrelipase are enzyme preparations made from animal pancreas, so they carry the same three enzyme families your own pancreas makes: amylase for starch, lipase for fat and protease for protein. Diastase is another amylase-type enzyme for starch. The label lists activity, not just weight: 17,400 USP amylase units, 3,200 USP lipase units and 15,400 USP protease units per capsule. USP units measure what an enzyme can do, which tells you more than its weight.\u003c\/p\u003e\n\u003cp\u003eWhy delayed release? Pancreatic enzymes are made for the near-neutral small intestine and lose activity in strong stomach acid. The complex is delayed release so it's designed to get past the stomach before it goes to work.† Most clinical research on pancreatic enzymes wasn't done in healthy adults, so we don't cite it here.\u003c\/p\u003e\n\u003ch3\u003eLipase and ox bile: the fat team\u003c\/h3\u003e\n\u003cp\u003eFat and water don't mix, so fat needs extra help before enzymes can get at it. Bile salts act like a detergent: they settle onto fat droplets, take part in fat breakdown, and help dissolve and carry fat-soluble nutrients toward absorption (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21236400\/\"\u003ea review of how bile salts work in digestion\u003c\/a\u003e). Super Enzymes+ pairs 75 mg of ox bile (bile from cattle) with the lipase in the pancreatic complex.†\u003c\/p\u003e\n\u003cp\u003eWhat the research shows: in a small double-blind crossover trial, 16 healthy adults took a 280 mg acid-resistant lipase capsule or a placebo right before a high-fat liquid meal. With lipase they reported less stomach fullness over the next hour, with no difference in bloating or nausea (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25287168\/\"\u003eLevine et al., lipase before a high-fat meal\u003c\/a\u003e). Honest limits: one meal, a small group, and a different lipase from the pancreatic lipase here, measured in units that don't compare directly.\u003c\/p\u003e\n\u003ch3\u003eThree proteases for protein\u003c\/h3\u003e\n\u003cp\u003eProtein gets help at three points. The pancreatic protease (15,400 USP units) works in the small intestine. The acid stable protease (50 mg at 500 SAPU\/g) is rated in SAPU, a unit of protease activity measured in acid, which tells you it's meant to work in the stomach. Papain (13 mg, 75,000 USP papain units) is the protein-splitting enzyme from papaya. Neither is marked delayed release on the label, so both can start on protein early.†\u003c\/p\u003e\n\u003cp\u003eWhat the research shows: in a randomized, double-blind crossover trial in 24 healthy young adults, a microbial protease blend taken with 25 g of whey protein made the first-hour rise in blood essential amino acids about 14% larger, and branched-chain amino acids about 15% larger, than placebo. Total amino acids and leucine didn't differ (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40675336\/\"\u003eHuang et al., protease with whey protein\u003c\/a\u003e). It was a different protease and a single shake, so it suggests added protease can speed early protein breakdown, not that this exact formula does.†\u003c\/p\u003e\n\u003ch3\u003eBetaine HCl (150 mg)\u003c\/h3\u003e\n\u003cp\u003eBetaine hydrochloride is betaine (a compound found in beets, spinach and whole grains) bound to hydrochloric acid, the same acid your stomach makes. Stomach acid switches on pepsin and starts unfolding proteins so enzymes can get at them. At 150 mg per capsule, this is a modest amount meant to work with the meal in the stomach.† We haven't found good trials of betaine HCl at this amount in healthy adults, so we aren't citing any.\u003c\/p\u003e\n\u003ch3\u003eFenugreek seed (100 mg) and the 32 mg blend\u003c\/h3\u003e\n\u003cp\u003eFenugreek is a seed spice used in curries and teas, with a long history in traditional digestive formulas. Human research on fenugreek mostly looks at outcomes other than digestion, so we include it as a traditional botanical and make no claim for it here.\u003c\/p\u003e\n\u003cp\u003eThe 32 mg proprietary blend adds choline bitartrate and inositol plus four herbs with a long mealtime tradition: hops strobiles, peppermint leaf, chamomile flower and yarrow flower. Each is a small amount: supporting cast, not the reason to buy the bottle.\u003c\/p\u003e\n\u003ch2\u003eHow to take Super Enzymes+\u003c\/h2\u003e\n\u003cp\u003eLabel directions, word for word: \"One to three capsules with water or juice, with each meal, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eTake it with food, not on an empty stomach: it's made for meals, and each capsule contains betaine HCl.\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. That includes acid-reducing medication, since this formula adds an acid source.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Super Enzymes+ has its own certificate of analysis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e Super Enzymes+ is made in our UL-certified cGMP facility in a farm town of about 3,500 in the Willamette Valley, where the formulators, makers and testers work under one roof and the owners work in the building too. We've been making supplements for 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many Super Enzymes+ capsules should I take?\u003c\/h3\u003e\n\u003cp\u003eThe label says one to three capsules with water or juice, with each meal. A simple start is one capsule at your largest meal, then adjust within that range.\u003c\/p\u003e\n\u003ch3\u003eShould I take it before, during or after a meal?\u003c\/h3\u003e\n\u003cp\u003eWith the meal, as the label directs. Enzymes work on the food they meet, so food needs to be there.\u003c\/p\u003e\n\u003ch3\u003eIs Super Enzymes+ vegetarian?\u003c\/h3\u003e\n\u003cp\u003eNo. Ox bile, pancreatin and pancrelipase come from animals, and the capsule shell is gelatin.\u003c\/p\u003e\n\u003ch3\u003eHow is this different from your Betaine HCl?\u003c\/h3\u003e\n\u003cp\u003eSuper Enzymes+ is a full enzyme formula with 150 mg of betaine HCl per capsule. Our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/betaine-hcl-stomach-digestion\"\u003eBetaine HCl with acid stable protease\u003c\/a\u003e sticks to the stomach stage: 649 mg of betaine HCl and 130 mg of acid stable protease per capsule. Because both contain betaine HCl, ask your practitioner before taking them together.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with a probiotic?\u003c\/h3\u003e\n\u003cp\u003eYes, they do different jobs. Enzymes break down the food in front of them, while a probiotic like our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/3-in-1-probiotic-fusion\"\u003e3-in-1 Probiotic Fusion\u003c\/a\u003e supplies live bacteria (here's \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/digestive\/digestive-health-and-the-gut-microbiome\"\u003ehow gut microbes fit into digestion\u003c\/a\u003e). Follow each label's directions.\u003c\/p\u003e\n\u003ch3\u003eHow soon will I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eIf you notice one, it will be around the meal you take it with, not weeks later, since enzymes act on that meal's food. Results vary.†\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, and bring the bottle so they can see the full label.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eWhitcomb DC et al. Human pancreatic digestive enzymes. Dig Dis Sci. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17205399\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eMaldonado-Valderrama J et al. The role of bile salts in digestion. Adv Colloid Interface Sci. 2011. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21236400\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eLevine ME et al. Lipase Supplementation before a High-Fat Meal Reduces Perceptions of Fullness in Healthy Subjects. Gut Liver. 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25287168\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHuang Y et al. Acute Effects of Oral Microbial Protease Co-ingestion with Whey Protein on Postprandial Plasma Amino Acid Concentrations, Appetite, and Satiety in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled, Crossover Clinical Trial. J Nutr. 2025. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40675336\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"100","offer_id":29641740035,"sku":"010-A3006","price":37.99,"currency_code":"USD","in_stock":true},{"title":"200","offer_id":29641740163,"sku":"010-A3008","price":59.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A3008_REV07_Listing_Image_1.png?v=1738257799"},{"product_id":"nice-bones","title":"Nice Bones Calcium, Magnesium \u0026 Vitamin D2 – Healthy Bone Support | 60 Tablets","description":"\u003cp\u003e\u003cstrong\u003eNice Bones is a daily bone supplement with 1,200 mg of calcium (carbonate, citrate, aspartate), 600 mg of magnesium (oxide, citrate, aspartate) and 25 mcg (1,000 IU) of vitamin D as ergocalciferol (D2) in every 3-tablet serving. Each bottle holds 60 vegetarian tablets, or 20 servings. Together, these three nutrients help maintain healthy bones and support normal calcium absorption.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNice Bones is for adults who want the three bone basics in one bottle instead of three, which is the idea behind \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/single-bottle-solution-what-is-it-and-why-do-we-put-it-on-our-premium-bottles\"\u003ethe \"Single Bottle Solution\" printed on our labels\u003c\/a\u003e. It fits people in their 30s and 40s building habits for the decades ahead, and people over 50 who plan to keep hiking, lifting and carrying their own groceries.\u003c\/p\u003e\n\u003cp\u003eYour skeleton isn't a finished project. Bone is broken down and rebuilt all the time, and it doubles as your body's calcium bank: more than 99% of the calcium in your body is stored in your bones and teeth, according to \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Calcium-HealthProfessional\/\"\u003ethe NIH calcium fact sheet\u003c\/a\u003e. Aging isn't optional. Getting old is. Keeping that bank funded is one simple, unglamorous part of adding life to your years.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Nice Bones\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupplies 1,200 mg of calcium, the main mineral in bones and teeth, to help maintain healthy bones.†\u003c\/li\u003e\n\u003cli\u003eAdds 600 mg of magnesium, a mineral your bones store and your body uses to build bone structure.†\u003c\/li\u003e\n\u003cli\u003eIncludes 25 mcg (1,000 IU) of vitamin D, which helps your body absorb calcium from food and supplements.†\u003c\/li\u003e\n\u003cli\u003eSupports normal muscle and nerve function, two jobs calcium and magnesium share.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin D (ergocalciferol)\u003c\/td\u003e\n\u003ctd\u003e25 mcg\u003c\/td\u003e\n\u003ctd\u003e125%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCalcium (carbonate, citrate, aspartate)\u003c\/td\u003e\n\u003ctd\u003e1,200 mg\u003c\/td\u003e\n\u003ctd\u003e92%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium (oxide, citrate, aspartate)\u003c\/td\u003e\n\u003ctd\u003e600 mg\u003c\/td\u003e\n\u003ctd\u003e142%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 3 vegetarian tablets. Servings per container: 20. Other ingredients: Cellulose, acacia, magnesium stearate, silica, and vegetable stearate. The label states: \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" It also says the tablets are processed with plant cellulose under the Sol-U-Tab® process \"assuring each tablet is completely solubilized within minutes of swallowing.\"\u003c\/p\u003e\n\u003ch2\u003eHow Nice Bones works\u003c\/h2\u003e\n\u003ch3\u003eCalcium: 1,200 mg from three forms\u003c\/h3\u003e\n\u003cp\u003eCalcium is the main mineral in bone, locked into a hard crystal called hydroxyapatite. Your blood, muscles and nerves need it too, and your body keeps blood calcium steady partly by drawing on what's stored in bone.\u003c\/p\u003e\n\u003cp\u003eWhy three forms? Calcium carbonate is 40% calcium by weight and calcium citrate is 21%, so carbonate helps fit 1,200 mg into three tablets. Carbonate absorbs best with a meal because it leans on stomach acid. Citrate leans on it less: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11329115\/\"\u003ea meta-analysis of 15 studies in 184 people\u003c\/a\u003e found absorption from calcium citrate was about 20% to 27% higher than from calcium carbonate, both on an empty stomach and with meals. Calcium aspartate is calcium bound to aspartic acid, an amino acid. The label doesn't list how much of the 1,200 mg comes from each form, so we won't put a single absorption number on the blend.\u003c\/p\u003e\n\u003cp\u003eWhat the research shows, straight: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26420598\/\"\u003ea review of 59 randomized trials in adults over 50\u003c\/a\u003e found calcium supplements raised bone mineral density by 0.7% to 1.8%. The gain showed up in the first year and didn't keep growing after that, and calcium from food did about the same. So calcium is a building material, not a shortcut, and it works alongside protein, the rest of your diet and regular movement.†\u003c\/p\u003e\n\u003ch3\u003eMagnesium: 600 mg from three forms\u003c\/h3\u003e\n\u003cp\u003eAbout 50% to 60% of the magnesium in your body sits in your bones. Magnesium helps build bone structure, helps move calcium across cell membranes, and works in more than 300 enzyme systems, including the ones behind normal muscle and nerve function (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Magnesium-HealthProfessional\/\"\u003eNIH magnesium fact sheet\u003c\/a\u003e).†\u003c\/p\u003e\n\u003cp\u003eMagnesium oxide packs the most magnesium per gram of the three forms, which helps fit 600 mg into three tablets. Citrate and aspartate are magnesium bound to citric acid and aspartic acid, and small studies summarized by the NIH found those forms are absorbed more completely than oxide. As with calcium, the label doesn't list how much comes from each form.\u003c\/p\u003e\n\u003cp\u003eThe research on magnesium and bone is earlier-stage than calcium's. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34666201\/\"\u003eA systematic review of studies in adults 60 and older\u003c\/a\u003e found higher magnesium intake was linked to higher bone mineral density at the hip. Those were observational studies with too little data to say anything about other parts of the skeleton, so read it as an association, not proof that a supplement builds bone.\u003c\/p\u003e\n\u003ch3\u003eVitamin D2: 25 mcg (1,000 IU)\u003c\/h3\u003e\n\u003cp\u003eVitamin D helps your gut absorb calcium and keeps blood calcium and phosphate at the levels bone needs to mineralize (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminD-HealthProfessional\/\"\u003ethe NIH vitamin D fact sheet\u003c\/a\u003e).† You can see the effect in \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12672710\/\"\u003ea study in middle-aged women\u003c\/a\u003e: calcium absorption from a 500 mg dose was 65% higher when their blood vitamin D averaged 86.5 nmol\/L than when it averaged 50 nmol\/L.\u003c\/p\u003e\n\u003cp\u003eNice Bones uses vitamin D2 (ergocalciferol), which comes from a non-animal source. Vitamin D3 (cholecalciferol) is the form your skin makes from sunlight. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18089691\/\"\u003ean 11-week trial in healthy adults aged 18 to 84\u003c\/a\u003e, 1,000 IU a day of D2 raised blood vitamin D just as much as 1,000 IU a day of D3. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22552031\/\"\u003eA 2012 meta-analysis of head-to-head trials\u003c\/a\u003e found D3 raised levels more overall, but the edge showed up with large, infrequent doses; with daily dosing, the difference wasn't significant. The NIH still notes that most evidence favors D3 for raising blood levels and holding them longer. If you'd rather have D3, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/everyday-liquid-sunshine-bone-imm\"\u003eEveryday Liquid Sunshine gives you 25 mcg of vitamin D3 in one drop\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eHow to take Nice Bones\u003c\/h2\u003e\n\u003cp\u003eThe label directions: \"Three tablets daily, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003ePractical notes from the NIH fact sheets linked above:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSplit it up with meals.\u003c\/strong\u003e Your body absorbs calcium best in doses of 500 mg or less, and calcium carbonate absorbs best with food. One tablet with each of three meals keeps each dose at about 400 mg of calcium.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCount your food.\u003c\/strong\u003e The upper limit for total calcium from food and supplements is 2,500 mg a day for adults 19 to 50 and 2,000 mg a day from age 51. If you eat a lot of dairy or fortified foods, add it up.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKnow the magnesium number.\u003c\/strong\u003e The upper limit for magnesium from supplements is 350 mg a day for adults, and Nice Bones gives you 600 mg at the full serving. More on that in the FAQ below.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e52 years and counting.\u003c\/strong\u003e We've been making supplements in Oregon since 1974. Bones aren't the only thing we plan to keep strong.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Nice Bones has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps the formulators, the makers and the testers under one roof. We've been owner-run since 2017, and the owners work in the building too.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much calcium, magnesium and vitamin D is in Nice Bones?\u003c\/h3\u003e\n\u003cp\u003eEach 3-tablet serving has 1,200 mg of calcium (92% of the Daily Value), 600 mg of magnesium (142%) and 25 mcg, or 1,000 IU, of vitamin D2 (125%). Per tablet, that works out to about 400 mg of calcium and 200 mg of magnesium.\u003c\/p\u003e\n\u003ch3\u003eIs 600 mg of magnesium a lot?\u003c\/h3\u003e\n\u003cp\u003eYes, it's on the high side: 142% of the Daily Value, and above the 350 mg a day upper limit the NIH lists for magnesium from supplements. The usual issue at higher amounts is loose stools, sometimes with nausea or cramping, and oxide is one of the forms most often linked to that. If it happens, or you already take magnesium, ask your healthcare practitioner what amount is right for you.\u003c\/p\u003e\n\u003ch3\u003eWhy vitamin D2 instead of D3?\u003c\/h3\u003e\n\u003cp\u003eNice Bones uses D2 (ergocalciferol), which is made from a non-animal source. At 1,000 IU a day, D2 kept up with D3 in the trial above, though the NIH notes that most evidence favors D3. If you want D3, Everyday Liquid Sunshine is our D3 drop.\u003c\/p\u003e\n\u003ch3\u003eCan I take Nice Bones with your other bone products?\u003c\/h3\u003e\n\u003cp\u003eYes, with a little math. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/bones-k2-comprehensive-bone-supp\"\u003eBones + K2\u003c\/a\u003e adds 500 mg of calcium, 40 mg of magnesium and 25 mcg of vitamin D3 per 2-capsule serving, so check your calcium and magnesium totals against the upper limits above. The label on \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/bone-power-strontium\"\u003eStrontium Bone Power\u003c\/a\u003e says to take it 2 hours before or after calcium products, because it will interfere with calcium absorption. Check with your practitioner before stacking.\u003c\/p\u003e\n\u003ch3\u003eHow long does a bottle last, and when will I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eA bottle is a 20-day supply at the label's serving of three tablets a day. You won't feel your bones change, and that's normal: bone turns over slowly, and the calcium trials above measured changes after a year or more. Think steady daily use, not quick results.†\u003c\/p\u003e\n\u003ch3\u003eIs Nice Bones safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner or pharmacist first. Calcium can get in the way of how some medications are absorbed, including certain antibiotics and thyroid hormone, so the timing between doses matters (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Calcium-HealthProfessional\/\"\u003ethe NIH lists which medications\u003c\/a\u003e). The same goes if you're pregnant, nursing, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/single-bottle-solution-what-is-it-and-why-do-we-put-it-on-our-premium-bottles\"\u003eWhat \"Single Bottle Solution\" on our bottles means\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calcium-citrate-60ct\"\u003eCalcium Citrate, 250 mg of calcium per capsule on its own\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eSakhaee K et al. Meta-analysis of calcium bioavailability: a comparison of calcium citrate with calcium carbonate. Am J Ther. 1999. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11329115\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eTai V et al. Calcium intake and bone mineral density: systematic review and meta-analysis. BMJ. 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26420598\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eGroenendijk I et al. Impact of magnesium on bone health in older adults: A systematic review and meta-analysis. Bone. 2022. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34666201\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHeaney RP et al. Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. J Am Coll Nutr. 2003. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12672710\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHolick MF et al. Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D. J Clin Endocrinol Metab. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18089691\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eTripkovic L et al. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. Am J Clin Nutr. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22552031\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364425920794,"sku":"015-A5004","price":19.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A5004_REV00_Necktag.png?v=1740400541"},{"product_id":"calming-magnesium-powder-relax","title":"Calming Mag Powder – Magnesium Drink for Relaxation and Restful Sleep | 300 g","description":"\u003cp\u003e\u003cstrong\u003eCalming Mag Powder is a berry-flavored magnesium drink mix with 400 mg of magnesium, 500 mg of glycine, 120 mg of vitamin C, 1,000 IU of vitamin D3, 15 mg of zinc, 98 mg of potassium and 3 mg of boron in every rounded scoop (about 5 grams). A 300 g tub holds 60 servings. Stirred into water at bedtime, it supports muscle relaxation and restful sleep.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCalming Mag Powder is for adults who want a simple wind-down habit: half a glass of water, one scoop, done before you brush your teeth. Magnesium is the main event. Your muscles and nerves use it every day, and national survey data summarized by the NIH show that about half of Americans get less magnesium from food than the average requirement for their age and sex.\u003c\/p\u003e\n\u003cp\u003eSleep and downtime are often the first things people in their 30s and 40s trade away. Aging isn't optional. Getting old is. A steady evening routine is an easy place to start adding life to your years.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Calming Mag Powder\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports normal muscle relaxation and nerve function with 400 mg of magnesium per scoop.†\u003c\/li\u003e\n\u003cli\u003eSupports restful sleep as part of a consistent bedtime routine.†\u003c\/li\u003e\n\u003cli\u003eSupports the body's normal response to occasional stress.†\u003c\/li\u003e\n\u003cli\u003ePairs 1,000 IU of vitamin D3 with the magnesium your body uses to activate it, for normal bone health.†\u003c\/li\u003e\n\u003cli\u003eAdds vitamin C and zinc, two nutrients that support normal immune function.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin C (ascorbic acid)\u003c\/td\u003e\n\u003ctd\u003e120 mg\u003c\/td\u003e\n\u003ctd\u003e200%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin D3 (cholecalciferol)\u003c\/td\u003e\n\u003ctd\u003e1,000 IU\u003c\/td\u003e\n\u003ctd\u003e250%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium (elemental)\u003c\/td\u003e\n\u003ctd\u003e400 mg\u003c\/td\u003e\n\u003ctd\u003e100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eZinc (elemental)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003e100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePotassium (elemental)\u003c\/td\u003e\n\u003ctd\u003e98 mg\u003c\/td\u003e\n\u003ctd\u003e2%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlycine\u003c\/td\u003e\n\u003ctd\u003e500 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBoron (elemental)\u003c\/td\u003e\n\u003ctd\u003e3 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: One (1) rounded scoop (approximately 5 grams). Servings per container: 60. Ingredients, as printed: Magnesium carbonate, citric acid, xylitol, glycine, natural berry and other natural flavors, potassium carbonate, ascorbic acid, boron citrate, zinc citrate, silica, and vitamin D3 (cholecalciferol). The label states: \"NO soy, salt, yeast, gluten, egg products, sugar, starch, or preservatives.\" The front label also carries Gluten-Free, Dairy-Free and Soy-Free icons.\u003c\/p\u003e\n\u003ch2\u003eHow Calming Mag Powder works\u003c\/h2\u003e\n\u003ch3\u003eMagnesium: 400 mg that dissolves as it fizzes\u003c\/h3\u003e\n\u003cp\u003eMagnesium is a mineral your body uses in more than 300 enzyme systems, including the ones behind muscle and nerve function, according to the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Magnesium-HealthProfessional\/\"\u003eNIH magnesium fact sheet\u003c\/a\u003e. It helps move calcium and potassium across cell membranes, which is part of how nerves fire and how muscles contract and then let go.†\u003c\/p\u003e\n\u003cp\u003eThe form is the interesting part. The tub holds magnesium carbonate and citric acid. Add water and they react: the fizz is carbon dioxide escaping as the carbonate meets the acid, and the minerals dissolve. The label puts it this way: \"The minerals are formed into citrate, glycinate, and ascorbate ionic forms naturally during the effervescent process.\"\u003c\/p\u003e\n\u003cp\u003eWhy does the citrate part matter? In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14596323\/\"\u003ea 60-day randomized, double-blind trial in 46 healthy adults\u003c\/a\u003e taking 300 mg of magnesium a day, citrate produced the highest blood magnesium levels of the forms tested, and magnesium oxide did no differently than placebo. Straight talk: one small study, a lower dose than ours, and it measured blood and urine levels, not how anyone slept.\u003c\/p\u003e\n\u003ch3\u003eWhat the sleep research shows, and what it doesn't\u003c\/h3\u003e\n\u003cp\u003eMagnesium and sleep is a promising, unfinished story. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35184264\/\"\u003eA systematic review of 9 studies covering 7,582 adults\u003c\/a\u003e found that observational studies link magnesium status with sleep quality and duration, while the randomized trials disagreed with each other.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40918053\/\"\u003ea placebo-controlled trial in 155 healthy adults who reported poor sleep\u003c\/a\u003e, 250 mg of magnesium a day (as bisglycinate) improved scores on a questionnaire about trouble falling and staying asleep by 3.9 points after 4 weeks, against 2.3 points on placebo. The researchers called the effect small. An exploratory analysis hinted that people who got less magnesium from food improved more, a lead the authors say needs more study.†\u003c\/p\u003e\n\u003ch3\u003eMagnesium and occasional stress\u003c\/h3\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33260549\/\"\u003eA review of magnesium and the stress response\u003c\/a\u003e describes magnesium as a brake in the body's normal stress signaling, and lays out a \"vicious circle\" idea: stress may increase the magnesium you lose, and running low may leave you more reactive to stress. It's a model built from lab and human studies, not a promise that one scoop makes a hard week easy.†\u003c\/p\u003e\n\u003ch3\u003eGlycine: 500 mg\u003c\/h3\u003e\n\u003cp\u003eGlycine is a non-essential amino acid, which means your body makes some on its own. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22529837\/\"\u003ea study of healthy volunteers whose sleep was cut by 25% for three nights\u003c\/a\u003e, 3 grams of glycine before bed reduced next-day fatigue and improved a reaction-time test compared with placebo. Notice the dose: 3 grams is six times the 500 mg in a scoop, so we won't claim this amount does the same.\u003c\/p\u003e\n\u003ch3\u003eVitamin D3: 1,000 IU\u003c\/h3\u003e\n\u003cp\u003eThis is D3 (cholecalciferol), the form your skin makes in sunlight; 1,000 IU equals 25 mcg. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29480918\/\"\u003eA review of magnesium's role in vitamin D activation\u003c\/a\u003e explains that the enzymes that process vitamin D in the liver and kidneys appear to need magnesium as a helper, and that activated vitamin D helps your body manage calcium and phosphate for normal bone maintenance.†\u003c\/p\u003e\n\u003ch3\u003eVitamin C, zinc, potassium and boron\u003c\/h3\u003e\n\u003cp\u003eVitamin C (120 mg, as ascorbic acid) and zinc (15 mg, from zinc citrate) both play a role in normal immune function, according to the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminC-HealthProfessional\/\"\u003eNIH vitamin C fact sheet\u003c\/a\u003e and the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Zinc-HealthProfessional\/\"\u003eNIH zinc fact sheet\u003c\/a\u003e.† Potassium is a small 98 mg, and boron (3 mg, from boron citrate) is a trace mineral with no established Daily Value. They round out the formula. The magnesium is the reason to buy it.\u003c\/p\u003e\n\u003ch2\u003eHow to take Calming Mag Powder\u003c\/h2\u003e\n\u003cp\u003eThe label's directions: \"One (1) rounded scoop (approximately 5 grams) in one half glass of water or juice for daily magnesium supplementation prior to retiring for sleep.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eExpect a fizz when the powder hits the water; that's the effervescent process the label describes. Let it settle before you drink.\u003c\/li\u003e\n\u003cli\u003eMagnesium from supplements can loosen stools. The NIH lists 350 mg a day as the adult upper limit for magnesium from supplements, and one scoop provides 400 mg, so if your digestion complains, ask your practitioner what amount suits you.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes, magnesium carbonate and glycine included.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e Or in a tub. More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Calming Mag Powder has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps formulators, makers and testers under one roof, and the owners work in the building too; the company has been owner-run since 2017. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much magnesium is in a scoop of Calming Mag Powder?\u003c\/h3\u003e\n\u003cp\u003eEach rounded scoop (about 5 grams) has 400 mg of elemental magnesium. Elemental means the magnesium itself, not the weight of the whole compound, so it's the number to compare. A 300 g tub holds 60 scoops, which is 60 nights at the label's serving.\u003c\/p\u003e\n\u003ch3\u003eWhen should I drink it?\u003c\/h3\u003e\n\u003cp\u003eAt bedtime. The label says to mix one rounded scoop into half a glass of water or juice \"prior to retiring for sleep.\" It doesn't say whether to take it with food.\u003c\/p\u003e\n\u003ch3\u003eHow soon will I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eIt varies, and some people won't feel much. In the 4-week trial above, the change was modest, and an exploratory analysis hinted at bigger improvements in people who got less magnesium from food. Give it a few weeks of nightly use, alongside a regular bedtime, before you judge it.†\u003c\/p\u003e\n\u003ch3\u003eDoes it have sugar in it?\u003c\/h3\u003e\n\u003cp\u003eNo. The label says no sugar. Its ingredient list includes xylitol, a sugar alcohol, and what the label calls \"natural berry and other natural flavors.\"\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Good Magnesium or Sleepy Sleep?\u003c\/h3\u003e\n\u003cp\u003eAdd up the magnesium first. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium\u003c\/a\u003e has 200 mg per capsule, so one capsule plus one scoop is 600 mg of supplemental magnesium a day, well past the 350 mg upper limit; ask your practitioner before doubling up. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/natural-sleep-aid-herbal-support\"\u003eSleepy Sleep\u003c\/a\u003e adds just 20 mg of magnesium per capsule, plus 1 mg of melatonin, 5-HTP and herbs, and its label says not to take it before driving or operating heavy equipment.\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner or pharmacist first. Magnesium can reduce how much of certain antibiotics and other prescription drugs you absorb, so the two may need to be taken hours apart.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/best-magnesium-supplements-for-sleep-2026\"\u003eHow magnesium forms and doses for sleep compare\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium, 200 mg of magnesium as a rice protein chelate per capsule\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/relaxation-supplement-passion-fl\"\u003eRelaxing Passion Flower, 50 mg of passionflower extract per lozenge\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/sleep-dots-melatonin-1mg\"\u003eSleep Dots, 1 mg melatonin you let dissolve\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eWalker AF et al. Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind study. Magnes Res. 2003. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14596323\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eArab A et al. The Role of Magnesium in Sleep Health: a Systematic Review of Available Literature. Biol Trace Elem Res. 2022. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35184264\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSchuster J et al. Magnesium Bisglycinate Supplementation in Healthy Adults Reporting Poor Sleep: A Randomized, Placebo-Controlled Trial. Nat Sci Sleep. 2025. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40918053\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003ePickering G et al. Magnesium Status and Stress: The Vicious Circle Concept Revisited. Nutrients. 2020. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33260549\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBannai M et al. The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Front Neurol. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22529837\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eUwitonze AM, Razzaque MS. Role of Magnesium in Vitamin D Activation and Function. J Am Osteopath Assoc. 2018. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29480918\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"300 g","offer_id":44364427133210,"sku":"015-A5008","price":47.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A5008_REV00_Necktag.png?v=1738588205"},{"product_id":"coq10-alpha-lipoic-acid","title":"CoQ10 100 mg Plus Alpha Lipoic Acid – Heart \u0026 Energy Support | 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eCoQ10 Plus Alpha Lipoic Acid is a once-a-day vegetarian capsule with 100 mg of CoQ10 (coenzyme Q10), 100 mg of lecithin (from soybean) and 5 mg of alpha lipoic acid. Each bottle holds 60 capsules, a 60-day supply at the label's serving of one capsule. CoQ10 helps your mitochondria turn food into usable energy and supports healthy heart function.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eYour body makes its own CoQ10, and the amount in most of your organs tends to peak in early adulthood and drift down from there. So this capsule is built for people in their late 30s and 40s who are already paying attention to energy and heart function, and for anyone over 50 who plans to keep going strong. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003ch2\u003eWhy people take CoQ10 Plus Alpha Lipoic Acid\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCellular energy.\u003c\/strong\u003e CoQ10 carries electrons inside your mitochondria, a step your cells need to make ATP, the energy they run on.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHealthy heart function.\u003c\/strong\u003e Your heart beats around the clock on energy made by its mitochondria, and CoQ10 is part of that machinery.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntioxidant support.\u003c\/strong\u003e CoQ10 and alpha lipoic acid both take part in the body's normal defenses against everyday oxidative stress.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeeping up your CoQ10.\u003c\/strong\u003e Organ levels of CoQ10 tend to decline after early adulthood, and a daily supplement raises the CoQ10 in your blood.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCoQ10 (Coenzyme Q10)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLecithin (from soybean)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAlpha Lipoic Acid\u003c\/td\u003e\n\u003ctd\u003e5 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established, as printed on the label. Serving size: 1 Vegetarian Capsule. Count: 60 vegetarian capsules, a 60-day supply at the label's serving. Other ingredients: Deep mined calcium phosphates, cellulose, vegetable cellulose (preservative-free, from capsule shell), magnesium trisilicate, silica, magnesium carbonate, \u0026amp; magnesium stearate. The label states: \"Uniquely formulated and emulsified to enhance the absorption of CoQ10.\" It also states: \"NO salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" Allergen statement: \"Contains soy, from lecithin.\"\u003c\/p\u003e\n\u003ch2\u003eHow CoQ10 Plus Alpha Lipoic Acid works\u003c\/h2\u003e\n\u003ch3\u003eCoQ10 (coenzyme Q10), 100 mg\u003c\/h3\u003e\n\u003cp\u003eCoQ10 is a fat-soluble, vitamin-like compound your body makes on its own. It sits in the inner membrane of your mitochondria and shuttles electrons between the protein complexes that produce ATP. In its reduced form it also acts as an antioxidant within cell membranes.†\u003c\/p\u003e\n\u003cp\u003eYour own supply changes with age. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2779364\/\"\u003ea study of organ samples from people aged one day to 81 years\u003c\/a\u003e, researchers in Sweden found that CoQ10 (ubiquinone) in the heart, lungs, liver, kidneys and spleen peaked around age 20 and then kept decreasing. It was a measurement study, not a supplement trial, and it's part of why we say start in your 30s and 40s.\u003c\/p\u003e\n\u003cp\u003eDoes a supplement actually get in? In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18318910\/\"\u003ea 14-day trial in 41 healthy trained and untrained adults\u003c\/a\u003e, 100 mg of CoQ10 twice a day significantly raised blood CoQ10. Time to exhaustion on a treadmill test trended longer but didn't reach statistical significance, and oxidative stress markers after a single dose moved in mixed directions. So CoQ10 clearly reached the blood, while performance changes in this healthy, mostly young group were small and uncertain. The daily dose was also twice what one of our capsules holds.\u003c\/p\u003e\n\u003ch3\u003eLecithin (from soybean), 100 mg\u003c\/h3\u003e\n\u003cp\u003eCoQ10 is a large, oily molecule, and your gut absorbs it slowly and only in part. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16551570\/\"\u003eA review of how CoQ10 is absorbed and used\u003c\/a\u003e, written by researchers at a CoQ10 supplement maker, reports that solubilized CoQ10 formulations show better absorption, that blood levels peak about 6 hours after a dose, and that the half-life is about 33 hours. That long half-life is one reason a once-a-day capsule makes sense.\u003c\/p\u003e\n\u003cp\u003eLecithin is a mix of phospholipids, the same family of fats that forms your cell membranes, and it works as an emulsifier, helping oil and water mix. That's what the label means by \"emulsified to enhance the absorption of CoQ10.\" We haven't published an absorption study of this exact capsule, so read that as design reasoning, not a measured result. Because the lecithin comes from soybeans, this formula contains soy.\u003c\/p\u003e\n\u003ch3\u003eAlpha lipoic acid (ALA), 5 mg\u003c\/h3\u003e\n\u003cp\u003eAlpha lipoic acid is a sulfur-containing compound your body makes in small amounts. Inside mitochondria it's a working part of the enzymes that break down fuel from food, so it shares a workplace with CoQ10.† \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7649494\/\"\u003eA review of lipoic acid's antioxidant chemistry\u003c\/a\u003e describes how ALA and its reduced form react with several kinds of reactive oxygen species and interact with vitamin C and glutathione, which in turn can help recycle vitamin E. The same review notes the reduced form may also act as a pro-oxidant by reducing iron, a reminder that antioxidant chemistry has two sides.\u003c\/p\u003e\n\u003cp\u003eAbout the dose: 5 mg is a small, supporting amount, and the human research we found used far more. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15327583\/\"\u003ea placebo-controlled crossover study in 16 healthy men\u003c\/a\u003e (average age 58), a single 600 mg dose showed up in the blood but didn't change measures of oxidative stress or blood vessel function over the next 90 minutes. So think of the ALA here as a companion to the CoQ10, not a standalone ALA dose. We don't claim a measurable effect from the ALA on its own.\u003c\/p\u003e\n\u003ch3\u003eWhat the research does and doesn't show\u003c\/h3\u003e\n\u003cp\u003eWe know of no published trial of this exact formula; the studies above test CoQ10 or ALA separately, over hours to weeks. They support that CoQ10 is part of how your cells make energy, that organ levels decline after early adulthood, and that supplements raise blood levels.† They don't promise you'll feel a specific difference by a specific date.\u003c\/p\u003e\n\u003ch2\u003eHow to take CoQ10 Plus Alpha Lipoic Acid\u003c\/h2\u003e\n\u003cp\u003eDirections from the label: One capsule daily, as a dietary supplement.\u003c\/p\u003e\n\u003cp\u003eThe label doesn't set a time of day or say whether to take it with food. CoQ10 is fat-soluble, so many people take it with a meal that has some fat in it.\u003c\/p\u003e\n\u003cp\u003eIf you also take another of our formulas that contains CoQ10 (see the FAQ below), add up your daily total. For context, \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19096117\/\"\u003ea safety review of CoQ10\u003c\/a\u003e, written by researchers at a CoQ10 ingredient maker, put the observed safe level from human trials at 1,200 mg a day.\u003c\/p\u003e\n\u003cp\u003eAllergen statement from the label: Contains soy, from lecithin. Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, CoQ10 and ALA included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Each one records what that lot was tested for and what the results were.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility is right there in it. The people who formulate this capsule, make it and test it all work under one roof, and the owners work in the building too (owner-run since 2017). We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much CoQ10 is in each capsule?\u003c\/h3\u003e\n\u003cp\u003eEach capsule has 100 mg of CoQ10, along with 100 mg of lecithin (from soybean) and 5 mg of alpha lipoic acid. One capsule is the full serving, so a 60-capsule bottle lasts 60 days at the label's directions.\u003c\/p\u003e\n\u003ch3\u003eWhen should I take it, and with food or without?\u003c\/h3\u003e\n\u003cp\u003eTake one capsule a day at whatever time you'll remember, since the label doesn't set one. Because CoQ10 is fat-soluble, many people take it with a meal that includes some fat.\u003c\/p\u003e\n\u003ch3\u003eHow long before I notice anything?\u003c\/h3\u003e\n\u003cp\u003eThere's no set timeline. In one trial in healthy adults, blood CoQ10 rose significantly within two weeks at 200 mg a day, but a blood level isn't the same as a difference you can feel, and people vary.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with YourHeart Nutrients or one of your multivitamins?\u003c\/h3\u003e\n\u003cp\u003eYou can, but count the CoQ10 in each. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/yourheart-nutrients-heart-health\"\u003eYourHeart Nutrients\u003c\/a\u003e has 100 mg of CoQ10 per 4-capsule serving, the \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-50-plus-multivitamin\"\u003eMen's 50+ Multivitamin\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-50-plus-multivitamin\"\u003eWomen's 50+ Multivitamin\u003c\/a\u003e each have 100 mg per 2-capsule serving, and the \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-multi-vitamin-60-capsules\"\u003eMen's Multi\u003c\/a\u003e has 50 mg per 2-capsule serving. Paired with this capsule, that's 150 to 200 mg a day, well under the 1,200 mg observed safe level in the safety review above. If you take medication, check with your practitioner first.\u003c\/p\u003e\n\u003ch3\u003eDoes it contain soy?\u003c\/h3\u003e\n\u003cp\u003eYes. The label says \"Contains soy, from lecithin.\" If you avoid soy, this formula isn't the right fit.\u003c\/p\u003e\n\u003ch3\u003eWill taking CoQ10 make my body stop making its own?\u003c\/h3\u003e\n\u003cp\u003eAccording to the safety review cited above, no. It concluded that supplemental CoQ10 doesn't appear to change the body's own CoQ10 production and doesn't build up in blood or tissue after you stop taking it.\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner before you start. Bring the bottle so they can read the full label.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mt-angel-vitamins-urolithin-a-500mg-cellular-energy-mitochondrial-renewal-60-capsules\"\u003eUrolithin A 500 mg\u003c\/a\u003e, one capsule a day, which supports mitochondrial renewal and cellular energy.†\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/single-bottle-solution-what-is-it-and-why-do-we-put-it-on-our-premium-bottles\"\u003eWhat \"Single Bottle Solution\" on our labels means\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eKalén A et al. Age-related changes in the lipid compositions of rat and human tissues. Lipids. 1989. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2779364\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCooke M et al. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18318910\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBhagavan HN et al. Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics. Free Radic Res. 2006. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16551570\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003ePacker L et al. alpha-Lipoic acid as a biological antioxidant. Free Radic Biol Med. 1995. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7649494\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSharman JE et al. Alpha-lipoic acid does not acutely affect resistance and conduit artery function or oxidative stress in healthy men. Br J Clin Pharmacol. 2004. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15327583\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHidaka T et al. Safety assessment of coenzyme Q10 (CoQ10). Biofactors. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19096117\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44427130536218,"sku":"015-A7004","price":25.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A7004_REV00_Listing_Image_1.png?v=1738257879"},{"product_id":"sleep-dots-melatonin-1mg","title":"Sleep Dots Melatonin 1 mg – Encourages Healthy Sleep | 60 Dissolvable Dots","description":"\u003cp\u003e\u003cstrong\u003eSleep Dots are a single-ingredient melatonin supplement: each dot holds 1 mg of pure crystalline melatonin and is made to dissolve in your mouth. The bottle holds 60 dots. Take one to six about half an hour before bedtime, per the label, to encourage healthy sleep and support your body's own sleep-wake cycle.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSleep Dots are for adults who want a little help falling asleep at bedtime on the nights sleep is slow to arrive, like after a late night or a weekend that pushed bedtime back.† The 1 mg dot is the whole idea: start small, and add more only if you need it.\u003c\/p\u003e\n\u003cp\u003eIf you're in your 30s or 40s, you're probably already working on the habits that decide how you'll feel at 70. Sleep sits underneath all of them. Aging isn't optional. Getting old is. A steady bedtime is one of the least glamorous ways to add life to your years, and a small dose of melatonin can help on the nights your schedule fights back.†\u003c\/p\u003e\n\u003ch2\u003eWhy people take Sleep Dots\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTo encourage healthy sleep, the job printed right on the label.†\u003c\/li\u003e\n\u003cli\u003eTo fall asleep more easily at bedtime, by adding to the \"it's night\" signal the body already sends.†\u003c\/li\u003e\n\u003cli\u003eTo support a healthy sleep-wake cycle, since melatonin is part of the system that keeps it on time.†\u003c\/li\u003e\n\u003cli\u003eTo start low: at 1 mg per dot, you can find the smallest amount that works for you within the label's one to six dots.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePure Crystalline Melatonin\u003c\/td\u003e\n\u003ctd\u003e1 mg\u003c\/td\u003e\n\u003ctd\u003e* (Daily Value Not Established)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eServing size:\u003c\/strong\u003e 1 Dot. \u003cstrong\u003eServings per container:\u003c\/strong\u003e not printed on the Supplement Facts panel; the bottle holds 60 dots. \u003cstrong\u003eOther ingredients:\u003c\/strong\u003e Lactose, Enhance™, acacia, cellulose, and magnesium stearate. \u003cstrong\u003eLabel statements:\u003c\/strong\u003e \"NO soy, salt, yeast, gluten, egg, sugar, starch, or preservatives.\" \"Formulated with Enhance™ metabolite uptake enhancers. Contains citrus products.\" \"Contains lactose, from milk.\"\u003c\/p\u003e\n\u003ch2\u003eHow Sleep Dots work\u003c\/h2\u003e\n\u003ch3\u003eMelatonin is your body's \"it's night\" signal\u003c\/h3\u003e\n\u003cp\u003eMelatonin is a hormone your body makes on its own. Levels rise at night, and bright light shuts that down: in a 1980 study, bright artificial light at night suppressed melatonin release in six healthy volunteers, while dimmer room light did not (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7434030\/\"\u003eLewy 1980\u003c\/a\u003e). So melatonin works as a timing signal. It tells the rest of your body what time it is.†\u003c\/p\u003e\n\u003cp\u003eThat signal shows up in body temperature. In a double-blind, placebo-controlled study of 20 healthy men, daytime doses from 0.1 to 10 mg lowered oral temperature, raised self-reported sleepiness, and shortened the time it took them to drift off in a simple sleep test (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8127888\/\"\u003eDollins 1994\u003c\/a\u003e).†\u003c\/p\u003e\n\u003ch3\u003eWhy 1 mg per dot\u003c\/h3\u003e\n\u003cp\u003eMore melatonin isn't automatically more useful. In that same study, blood levels rose in step with the dose, and the 0.1 mg and 0.3 mg doses produced peaks inside the normal nighttime range (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8127888\/\"\u003eDollins 1994\u003c\/a\u003e). A second sleep-lab study gave 12 healthy young volunteers 0.3 mg, 1 mg or a placebo at 9 PM, two to four hours before their usual bedtime. Both doses shortened the time it took to fall asleep, neither changed the overall structure of their sleep, and neither left people worse off on next-morning mood or performance tests (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e).†\u003c\/p\u003e\n\u003cp\u003eThat's the case for a 1 mg dot: a small dose in the range those studies used, so you can stay at one if it does the job.\u003c\/p\u003e\n\u003ch3\u003eWhat the research does and doesn't show\u003c\/h3\u003e\n\u003cp\u003eThe low-dose studies are small sleep-lab trials, mostly in healthy young men. They measured how quickly people fell asleep, not how rested they felt weeks later, and none tested dissolvable dots or half-hour timing. The honest summary: the research supports falling asleep a bit more easily, not a dramatic change.†\u003c\/p\u003e\n\u003ch3\u003eWhy a dot that dissolves in your mouth\u003c\/h3\u003e\n\u003cp\u003eThe label directs you to let the dots dissolve in your mouth. For context, a systematic review of 22 studies found that oral, immediate-release melatonin peaked in the blood about 50 minutes after a dose, had a half-life of about 45 minutes, and only about 15% reached the bloodstream (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26008214\/\"\u003eHarpsøe 2015\u003c\/a\u003e). Those numbers come from other oral forms, and we haven't found good published data comparing dissolvable dots with tablets, so we don't claim the dots work faster. The short half-life does mean melatonin doesn't linger, which suits a bedtime dose.†\u003c\/p\u003e\n\u003ch3\u003eWhat else is in the dot\u003c\/h3\u003e\n\u003cp\u003eLactose (milk sugar) is the first of the other ingredients listed, hence \"Contains lactose, from milk.\" Acacia is a plant gum, cellulose is a plant fiber, and magnesium stearate is a common manufacturing aid. The label describes Enhance™ as \"metabolite uptake enhancers\" and notes that the dots contain citrus products; we quote the label and make no further claim about it.\u003c\/p\u003e\n\u003ch3\u003eWhy the number on the label matters\u003c\/h3\u003e\n\u003cp\u003eWith melatonin, the label and the bottle don't always agree. In a 2017 lab analysis of 31 melatonin supplements, measured melatonin ranged from 83% below to 478% above the label amount, and one product varied by as much as 465% from lot to lot (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27855744\/\"\u003eErland 2017\u003c\/a\u003e). When the point is a small, precise dose, that's worth checking, and every lot of Sleep Dots has a certificate of analysis.\u003c\/p\u003e\n\u003ch2\u003eHow to take Sleep Dots\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDirections (from the label):\u003c\/strong\u003e \"As a dietary supplement, allow one to six dots dissolve in mouth 1\/2 hour before bedtime. Best if taken on an empty stomach.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStart with one dot.\u003c\/strong\u003e If that isn't enough, add one at a time on later nights, staying within the label's six.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep it for bedtime.\u003c\/strong\u003e In the 1994 study, melatonin made people sleepier and less accurate on an alertness task (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8127888\/\"\u003eDollins 1994\u003c\/a\u003e), so take it only when you're done driving for the night.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkip bright light before bed.\u003c\/strong\u003e Bright light at night shuts down your own melatonin release (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7434030\/\"\u003eLewy 1980\u003c\/a\u003e), so keeping bright lights off near bedtime lets your own signal do its job too.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWarning (from the label):\u003c\/strong\u003e \"Not recommended while pregnant or lactating unless directed by health care practitioner. Individuals under 18 years old consult with health care practitioner before use.\" The label also states \"Contains lactose, from milk.\" Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test. We test every incoming ingredient lot, the melatonin included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\/wake-sleep-dots-120-dots\"\u003eSee the certificates of analysis for this product\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 in the Willamette Valley, and our UL-certified cGMP facility is right in it. The people who formulate, make and test Sleep Dots work under one roof, and the owners work in the building too; the company has been owner-run since 2017. We've been making supplements in Oregon since 1974. Fifty-two years in, we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many Sleep Dots should I take?\u003c\/h3\u003e\n\u003cp\u003eThe label says one to six dots, 1\/2 hour before bedtime, which is 1 to 6 mg of melatonin. A sensible start is one dot, adding more on later nights only if needed, since the sleep-lab studies saw an effect at 1 mg and below (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e).†\u003c\/p\u003e\n\u003ch3\u003eWhen should I take Sleep Dots, and with or without food?\u003c\/h3\u003e\n\u003cp\u003eAbout half an hour before bedtime, on an empty stomach, per the label. Eating is one of the factors a systematic review found can change how the body handles melatonin (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26008214\/\"\u003eHarpsøe 2015\u003c\/a\u003e).\u003c\/p\u003e\n\u003ch3\u003eHow soon will I notice a difference?\u003c\/h3\u003e\n\u003cp\u003ePossibly the first night. In the sleep-lab studies, a single evening dose shortened the time healthy volunteers took to fall asleep that same night (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e). Expect to fall asleep a bit more easily, not a dramatic change.†\u003c\/p\u003e\n\u003ch3\u003eWill Sleep Dots make me groggy the next morning?\u003c\/h3\u003e\n\u003cp\u003eNot at the doses tested in the 1996 study: neither 0.3 mg nor 1 mg left people worse off on next-morning mood or performance tests (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e).† A 2016 review of the safety research reported only mild side effects, such as dizziness, headache, nausea and sleepiness (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26692007\/\"\u003eAndersen 2016\u003c\/a\u003e).\u003c\/p\u003e\n\u003ch3\u003eCan I take Sleep Dots with Sleepy Sleep or Melatonin 3 mg Timed Release?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, since both contain melatonin too. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/natural-sleep-aid-herbal-support\"\u003eSleepy Sleep\u003c\/a\u003e has 1 mg per capsule alongside herbs and 5-HTP, and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/melatonin-3mg-timed-release\"\u003eMelatonin 3 mg Timed Release\u003c\/a\u003e has 3 mg per capsule; its label says it releases about 1.5 mg in the first hour and the rest over the next five hours. No label gives directions for combining them, so the simple approach is to pick one.\u003c\/p\u003e\n\u003ch3\u003eAre Sleep Dots safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner before you start. Some medications change how the body handles melatonin, including oral contraceptives and fluvoxamine, and so do caffeine and smoking (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26008214\/\"\u003eHarpsøe 2015\u003c\/a\u003e).\u003c\/p\u003e\n\u003ch3\u003eDo Sleep Dots contain dairy or gluten?\u003c\/h3\u003e\n\u003cp\u003eThey contain lactose, from milk; the label says so directly. The label also says \"NO soy, salt, yeast, gluten, egg, sugar, starch, or preservatives\" and \"Contains citrus products.\" If you avoid milk or citrus, Sleep Dots aren't a fit.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium\u003c\/a\u003e: 200 mg of magnesium as a rice protein chelate in each capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calming-magnesium-powder-relax\"\u003eCalming Mag Powder\u003c\/a\u003e: 400 mg of magnesium and 500 mg of glycine per scoop, stirred into water before bed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eLewy AJ et al. Light suppresses melatonin secretion in humans. Science. 1980. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7434030\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDollins AB et al. Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proc Natl Acad Sci U S A. 1994. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8127888\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eZhdanova IV et al. Effects of low oral doses of melatonin, given 2-4 hours before habitual bedtime, on sleep in normal young humans. Sleep. 1996. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHarpsøe NG et al. Clinical pharmacokinetics of melatonin: a systematic review. Eur J Clin Pharmacol. 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26008214\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eErland LA, Saxena PK. Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin Content. J Clin Sleep Med. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27855744\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAndersen LP et al. The Safety of Melatonin in Humans. Clin Drug Investig. 2016. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26692007\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364425527578,"sku":"015-A7007","price":15.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A7007_REV00_Necktag.png?v=1747248651"},{"product_id":"melatonin-3mg-timed-release","title":"Melatonin 3 mg Time Released – Sustained Sleep Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eMelatonin 3 mg Time Released is a single-ingredient sleep supplement. Each vegetarian capsule holds 3 mg of pure crystalline melatonin, and the label says about 1.5 mg is released in the first hour and the rest over the next five hours. The bottle holds 60 capsules. Take one half an hour before bedtime to promote sustained sleep and support a healthy sleep-wake cycle.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis one is for adults who drift off fine but want support that lasts past lights-out, on nights when sleep seems to run out before the alarm does. Regular melatonin clears your bloodstream quickly; this capsule spreads its 3 mg over about six hours, per the label.†\u003c\/p\u003e\n\u003cp\u003eIf you're in your 30s or 40s, you're probably already working on energy, food and exercise so you can keep going strong at 75. Sleep sits underneath all of it. Aging isn't optional. Getting old is. A steady bedtime is one of the least glamorous ways to add life to your years.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Melatonin 3 mg Time Released\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTo promote sustained sleep, the job printed right on the label.†\u003c\/li\u003e\n\u003cli\u003eTo settle into sleep more easily, with about 1.5 mg of melatonin released in the first hour, according to the label.†\u003c\/li\u003e\n\u003cli\u003eTo keep melatonin support going after that first hour, as the remaining 1.5 mg is released over the next five hours.†\u003c\/li\u003e\n\u003cli\u003eTo support a healthy sleep-wake cycle, since melatonin is the signal your body uses to tell night from day.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePure Crystallin Melatonin\u003c\/td\u003e\n\u003ctd\u003e3 mg\u003c\/td\u003e\n\u003ctd\u003e* (Daily Value Not Established)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eServing size:\u003c\/strong\u003e 1 Vegetarian Capsule. \u003cstrong\u003eServings per container:\u003c\/strong\u003e 60 (the bottle holds 60 vegetarian capsules, one capsule per serving), a 60-day supply at the label's serving. \u003cstrong\u003eOther ingredients:\u003c\/strong\u003e Enhance™, cellulose, deep mined calcium phosphate, vegetable cellulose (preservative-free, from capsule shell), magnesium trisilicate, silica, and magnesium stearate. \u003cstrong\u003eLabel statements:\u003c\/strong\u003e \"NO soy, salt, yeast, gluten, egg, sugar, starch, or preservatives.\" \"Releases approximately 1.5 mg of Melatonin in the first hour and the balance over the next five hour period.\" \"Formulated with Enhance™ metabolite uptake enhancers. Contains citrus products.\"\u003c\/p\u003e\n\u003ch2\u003eHow Melatonin 3 mg Time Released works\u003c\/h2\u003e\n\u003ch3\u003eMelatonin is your body's \"it's night\" signal\u003c\/h3\u003e\n\u003cp\u003eMelatonin is a hormone made mostly by the pineal gland, deep in the brain. Your body releases it at night, and bright light turns it down: in a classic 1980 study, bright artificial light suppressed nighttime melatonin in six healthy people, while dimmer ordinary room light did not (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7434030\/\"\u003eLewy 1980\u003c\/a\u003e). Think of it as a clock signal, not a knockout pill.†\u003c\/p\u003e\n\u003cp\u003eA little extra adds to that signal. In a sleep-lab study, 12 healthy young volunteers took 0.3 mg of melatonin, 1 mg, or a placebo at 9 PM. Both doses shortened the time it took to fall asleep, and neither changed the structure of their sleep or hurt next-morning mood and performance (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e).†\u003c\/p\u003e\n\u003ch3\u003eWhy time released\u003c\/h3\u003e\n\u003cp\u003eSwallowed melatonin doesn't hang around. A systematic review of 22 studies found that immediate-release melatonin peaked about 50 minutes after a dose with a half-life of about 45 minutes, and only about 15% of an oral dose reached the bloodstream (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26008214\/\"\u003eHarpsøe 2015\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eA slow-release design stretches that out. In a 1985 study, 2 mg of melatonin in a regular gelatin capsule or an oil solution kept blood levels at or above normal nighttime levels for 3 to 4 hours, while a slow-release pill kept them high for 5 to 7 hours (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3994899\/\"\u003eAldhous 1985\u003c\/a\u003e). Per the label, this capsule releases about 1.5 mg in the first hour to help you settle in, and the other 1.5 mg over the next five hours to keep the signal going.†\u003c\/p\u003e\n\u003ch3\u003eWhy timing matters as much as dose\u003c\/h3\u003e\n\u003cp\u003eMelatonin also nudges your body clock, so timing counts. In a lab study of 34 healthy adults aged 18 to 42, a 0.5 mg dose shifted the timing of the body clock; compared with the same team's earlier 3 mg study, run the same way, both doses moved the clock by similar amounts when each was taken at its own ideal time (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20410229\/\"\u003eBurgess 2010\u003c\/a\u003e). This capsule's label sets the timing: half an hour before bedtime.†\u003c\/p\u003e\n\u003ch3\u003eWhat the research does and doesn't show\u003c\/h3\u003e\n\u003cp\u003eThe healthy-adult studies are small and short, and none tested this exact capsule. The slow-release data come from a 2 mg pill studied in 1985; this product's release pattern is the one stated on its label. We haven't found healthy-adult trials measuring how much extra sleep a time-released form adds, so we won't promise extra hours. What the evidence supports is modest: melatonin helps tell your body it's night, and slow release keeps that signal up longer.†\u003c\/p\u003e\n\u003ch3\u003eWhat else is in the capsule\u003c\/h3\u003e\n\u003cp\u003eThe shell is vegetable cellulose, which is why the label calls it a vegetarian capsule. Everything else in the capsule is listed above exactly as the label prints it. The label describes Enhance™ as \"metabolite uptake enhancers\" and says the capsules contain citrus products; we make no further claim about it.\u003c\/p\u003e\n\u003ch2\u003eHow to take Melatonin 3 mg Time Released\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDirections (from the label):\u003c\/strong\u003e \"One capsule 1\/2 hour before bedtime on an empty stomach, as a dietary supplement.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkip the bedtime snack.\u003c\/strong\u003e The label says empty stomach, and in the 1985 study, when the slow-release form peaked depended heavily on whether people had eaten (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3994899\/\"\u003eAldhous 1985\u003c\/a\u003e).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTake it when you're done for the night.\u003c\/strong\u003e Sleepiness is one of melatonin's known mild side effects (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26692007\/\"\u003eAndersen 2016\u003c\/a\u003e), so don't take it before driving or anything that needs you alert.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkip the bright lights.\u003c\/strong\u003e Bright light at night turns down your own melatonin (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7434030\/\"\u003eLewy 1980\u003c\/a\u003e), so save brightly lit tasks for earlier in the evening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCaution (from the label):\u003c\/strong\u003e \"Individuals under 18 years old, under a physician's care, or pregnant and lactating women, or those considering pregnancy, should consult their health care practitioner before using.\" Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, the melatonin included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are rejected.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every production lot of this capsule has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 in the Willamette Valley, and it's home to our UL-certified cGMP facility. The people who formulate, make and test this capsule work under one roof, and the owners work in the building too; we've been owner-run since 2017. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow is time-released melatonin different from regular melatonin?\u003c\/h3\u003e\n\u003cp\u003eIt releases its dose gradually instead of all at once: per the label, about 1.5 mg in the first hour and the other 1.5 mg over the next five hours. Regular melatonin peaks within about an hour and fades within a few hours; a slow-release form kept blood levels up for 5 to 7 hours in a 1985 study (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3994899\/\"\u003eAldhous 1985\u003c\/a\u003e).†\u003c\/p\u003e\n\u003ch3\u003eWhen should I take it, and with or without food?\u003c\/h3\u003e\n\u003cp\u003eHalf an hour before bedtime, on an empty stomach, per the label. Food is one of the factors known to change how the body handles melatonin (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26008214\/\"\u003eHarpsøe 2015\u003c\/a\u003e), and with a slow-release form it shifted when the peak arrived (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3994899\/\"\u003eAldhous 1985\u003c\/a\u003e).\u003c\/p\u003e\n\u003ch3\u003eIs 3 mg too much melatonin?\u003c\/h3\u003e\n\u003cp\u003eNot according to the safety research, though the label's one capsule is the place to stay. A 2016 review found short-term melatonin use safe even at very high doses, with only mild side effects reported, such as dizziness, headache, nausea and sleepiness (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26692007\/\"\u003eAndersen 2016\u003c\/a\u003e). The lab studies above saw effects at doses of 1 mg and below, so if you'd rather start smaller, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/sleep-dots-melatonin-1mg\"\u003eSleep Dots with 1 mg of melatonin per dot\u003c\/a\u003e are made for that.\u003c\/p\u003e\n\u003ch3\u003eWill it make me groggy in the morning?\u003c\/h3\u003e\n\u003cp\u003eIt might. In the 1996 sleep-lab study, 1 mg or less didn't hurt next-morning mood or performance (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e), but this capsule has 3 mg, and sleepiness is one of melatonin's known mild side effects (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26692007\/\"\u003eAndersen 2016\u003c\/a\u003e). Take it only at bedtime, and if mornings feel foggy, ask your practitioner about a smaller dose.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Sleep Dots or Sleepy Sleep?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, because both contain melatonin. Sleep Dots have 1 mg per dot, and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/natural-sleep-aid-herbal-support\"\u003eSleepy Sleep, our herbal blend with 1 mg of melatonin\u003c\/a\u003e, pairs it with chamomile, hops, lemon balm, passionflower and 25 mg of 5-HTP per capsule. None of the labels give directions for combining them, so the simple approach is to pick one.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with magnesium?\u003c\/h3\u003e\n\u003cp\u003eNothing on these labels says not to. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium, 200 mg of magnesium per capsule\u003c\/a\u003e, uses a rice protein chelate, and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calming-magnesium-powder-relax\"\u003eCalming Mag Powder, a magnesium drink for before bed\u003c\/a\u003e, has 400 mg of magnesium and 500 mg of glycine per scoop. Neither one contains melatonin. If you take medication, check with your practitioner first.\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner before you start. Some medicines change how the body handles melatonin, including oral contraceptives and fluvoxamine, and so do caffeine and smoking (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26008214\/\"\u003eHarpsøe 2015\u003c\/a\u003e). The label also asks anyone under a physician's care to check first.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eLewy AJ et al. Light suppresses melatonin secretion in humans. Science. 1980. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7434030\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eZhdanova IV et al. Effects of low oral doses of melatonin, given 2-4 hours before habitual bedtime, on sleep in normal young humans. Sleep. 1996. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHarpsøe NG et al. Clinical pharmacokinetics of melatonin: a systematic review. Eur J Clin Pharmacol. 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26008214\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAldhous M et al. Plasma concentrations of melatonin in man following oral absorption of different preparations. Br J Clin Pharmacol. 1985. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3994899\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBurgess HJ et al. Human phase response curves to three days of daily melatonin: 0.5 mg versus 3.0 mg. J Clin Endocrinol Metab. 2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20410229\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAndersen LP et al. The Safety of Melatonin in Humans. Clin Drug Investig. 2016. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26692007\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44398256718106,"sku":"015-M7008","price":19.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A7008_REV00_Necktag.png?v=1738257924"},{"product_id":"msm-2000mg-joint-health-support","title":"MSM 2000 mg – Healthy Joint \u0026 Bone Support | 60 Vegetarian Tablets","description":"\u003cp\u003e\u003cstrong\u003eMSM 2000 is a single-ingredient supplement: each vegetarian tablet holds 2,000 mg of MSM (methylsulfonylmethane), a sulfur compound found in small amounts in everyday foods, with no additives, per the label. One tablet is one serving, so the 60-tablet bottle is a 60-day supply. MSM supplies sulfur, a building block for healthy joints and bones.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eJoints are one of those things you don't think about until they start leaving you notes. If you run, hike, lift, garden or chase kids around, and you plan to keep doing all of it in your 70s and 80s, your 30s and 40s are a good time to start paying attention. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003cp\u003eMSM 2000 keeps it simple: one ingredient, 2,000 mg, one tablet a day. It's an easy place to start a joint routine, or an easy add-on to the one you already have.\u003c\/p\u003e\n\u003ch2\u003eWhy people take MSM 2000\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eProvides 2,000 mg of MSM, a dietary source of sulfur, a building block for healthy joints and bones.†\u003c\/li\u003e\n\u003cli\u003eMay support joint and muscle comfort after hard workouts (early, small studies so far).†\u003c\/li\u003e\n\u003cli\u003eSupports the body's own antioxidant defenses during strenuous exercise.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003e100% Pure MSM (methyl sulfonyl methane)\u003c\/td\u003e\n\u003ctd\u003e2,000 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value Not Established. Serving size: 1 Vegetarian Tablet. The panel doesn't print a servings-per-container number; at one tablet per serving, the 60-tablet bottle holds 60 servings. No other ingredients are listed. The label reads \"100% Pure MSM - No Additives\" and \"HPLC TESTED,\" and states: \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow MSM 2000 works\u003c\/h2\u003e\n\u003ch3\u003eWhat MSM is\u003c\/h3\u003e\n\u003cp\u003eMSM, short for methylsulfonylmethane (also called dimethyl sulfone), is a small sulfur-containing compound. It turns up in fruits, vegetables, grains, coffee, tea and cow's milk, but only in trace amounts, measured in hundredths of a part per million. That's why it comes in supplement form: MSM for supplements is typically made by oxidizing DMSO, its parent compound, and then purifying it, and a \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28300758\/\"\u003e2017 review of MSM's uses and safety\u003c\/a\u003e notes that manufactured MSM has no detectable structural or safety differences from the MSM found in nature.\u003c\/p\u003e\n\u003ch3\u003eWhy sulfur matters\u003c\/h3\u003e\n\u003cp\u003eSulfur is part of the amino acids methionine and cysteine, which your body uses to build proteins, and the label calls MSM a \"building block for healthy bones \u0026amp; joints.\"† The idea behind MSM is that it can act as a dietary sulfur donor. Here's the candid part: an animal study found sulfur from MSM in blood proteins, but how much of it the human body uses this way hasn't been pinned down. What is clear, per the same review, is that people absorb MSM quickly (in under an hour), and in healthy men taking 3 grams a day, blood MSM levels in most of them kept rising from week 2 to week 4. Translation: it builds up with daily use, so a steady daily habit is the point.\u003c\/p\u003e\n\u003ch3\u003eWhat the joint research shows\u003c\/h3\u003e\n\u003cp\u003eThe joint research in healthy, active people is still small. In one trial, 22 healthy adults training for a half-marathon took 3 grams of MSM or a placebo for three weeks before the race. Runners on MSM reported less muscle and joint discomfort afterward, by a margin the researchers considered meaningful, but the difference wasn't statistically significant, and markers of oxidative stress and muscle damage didn't differ between groups (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28736511\/\"\u003eWithee 2017, half-marathon trial\u003c\/a\u003e). The 2017 review adds that the best dose and timing for MSM are still being worked out, so read this as an early signal, not the final word.\u003c\/p\u003e\n\u003ch3\u003eExercise recovery and antioxidant support\u003c\/h3\u003e\n\u003cp\u003eHard exercise temporarily raises oxidative stress, a normal part of training. In one 10-day trial, 18 untrained young men took MSM (50 mg per kilogram of body weight, about 3.5 grams for a 154-pound man) or a placebo, then ran 14 km. The MSM group finished with lower oxidative stress markers and higher glutathione levels (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21899544\/\"\u003eNakhostin-Roohi 2011, 14 km run study\u003c\/a\u003e). In an eight-man pilot study with no placebo group, 3 grams a day for about four weeks raised blood antioxidant capacity after a tough leg workout (18 sets of knee extensions), with a trend toward less soreness than 1.5 grams a day, and no change in workout performance (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23013531\/\"\u003eKalman 2012 pilot study\u003c\/a\u003e).†\u003c\/p\u003e\n\u003cp\u003eThe honest limits: these studies are small and short, most of them used more MSM than one tablet provides, and none of them measured bone. We'd rather tell you what they don't show than oversell them.\u003c\/p\u003e\n\u003ch3\u003eWhy one 2,000 mg tablet\u003c\/h3\u003e\n\u003cp\u003eMSM 2000 puts the whole serving in a single tablet. The label lists MSM and nothing else, so it's easy to pair with other joint products without guessing what's doubled up. And because MSM builds up with steady use, one tablet a day is a routine you can actually keep.\u003c\/p\u003e\n\u003ch2\u003eHow to take MSM 2000\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDirections (from the label):\u003c\/strong\u003e One tablet daily, as a dietary supplement.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThe label doesn't say what time of day or whether to take it with food. Pick a time you'll remember, since MSM builds up with steady daily use.\u003c\/li\u003e\n\u003cli\u003eIt's a big tablet (it holds 2,000 mg of MSM), so take it with a full glass of water.\u003c\/li\u003e\n\u003cli\u003eSeveral of the studies above used 3 grams a day. Stick with the label's one tablet unless your healthcare practitioner tells you otherwise.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, including the MSM that goes into this tablet, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of MSM 2000 gets its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e That's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility sits right in it. The people who formulate, make and test MSM 2000 work under one roof, and the owners work in the building too (owner-run since 2017). We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much MSM is in MSM 2000?\u003c\/h3\u003e\n\u003cp\u003eEach vegetarian tablet contains 2,000 mg of MSM, and one tablet is the full serving. At one tablet a day, the 60-tablet bottle is a 60-day supply.\u003c\/p\u003e\n\u003ch3\u003eShould I take MSM with food?\u003c\/h3\u003e\n\u003cp\u003eThe label doesn't say, so it's your call. Taking it with a meal and a full glass of water is an easy way to turn it into a daily habit.\u003c\/p\u003e\n\u003ch3\u003eHow long does MSM take to work?\u003c\/h3\u003e\n\u003cp\u003eGive it about a month of daily use before you judge it. The studies above ran from 10 days to about a month, and blood MSM levels keep building over the first weeks of daily use. Results vary, and some people won't notice much.\u003c\/p\u003e\n\u003ch3\u003eCan I take MSM 2000 with Joint Solution Advanced or Inflameze?\u003c\/h3\u003e\n\u003cp\u003eYes, and they're sold together as the \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-mobility-stack-inflameze-msm\"\u003eJoint + Mobility Stack with MSM 2000, Inflameze and Joint Solution Advanced\u003c\/a\u003e. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-support-advanced\"\u003eJoint Solution Advanced\u003c\/a\u003e lists 700 mg of MSM per 4-capsule serving, so one MSM 2000 tablet plus a full 4-capsule serving comes to 2,700 mg of MSM, below the 4 grams a day the 2017 review describes as well tolerated. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/inflameze-botanical-joint-support\"\u003eInflameze\u003c\/a\u003e contains no MSM. Joint Solution Advanced includes glucosamine from crab shell, so check that label if you avoid shellfish.\u003c\/p\u003e\n\u003ch3\u003eIs MSM the same as DMSO?\u003c\/h3\u003e\n\u003cp\u003eNo. They're different compounds. DMSO is MSM's parent compound, and the MSM used in supplements (also called dimethyl sulfone) is typically made by oxidizing DMSO and purifying the result. MSM is odorless, and it's the only ingredient in this tablet.\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take MSM every day?\u003c\/h3\u003e\n\u003cp\u003eFor most healthy adults, yes: the 2017 review describes MSM as well tolerated at up to 4 grams a day, with few, mild side effects. One MSM 2000 tablet is 2 grams. If you take medication, are pregnant or nursing, or have a medical condition, ask your healthcare practitioner first.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/our-approach-to-raw-material-sourcing-and-testing\"\u003eHow we source and test raw materials before they're used\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-support-structure-and-comfort\"\u003eJoint Solution, glucosamine-based joint support without MSM\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/bones-k2-comprehensive-bone-supp\"\u003eBones + K2, with calcium from Aquamin and vitamins D3 and K2\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eButawan M et al. Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28300758\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWithee ED et al. Effects of Methylsulfonylmethane (MSM) on exercise-induced oxidative stress, muscle damage, and pain following a half-marathon: a double-blind, randomized, placebo-controlled trial. J Int Soc Sports Nutr. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28736511\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eNakhostin-Roohi B et al. Effect of chronic supplementation with methylsulfonylmethane on oxidative stress following acute exercise in untrained healthy men. J Pharm Pharmacol. 2011. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21899544\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKalman DS et al. Influence of methylsulfonylmethane on markers of exercise recovery and performance in healthy men: a pilot study. J Int Soc Sports Nutr. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23013531\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424642842,"sku":"015-A7010","price":19.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A7010_REV00_Necktag.png?v=1739302313"},{"product_id":"5-htp","title":"5-HTP 100 mg – Healthy Mood and Sleep Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eMt. Angel Vitamins 5-HTP gives you 100 mg of 5-hydroxytryptophan from Griffonia simplicifolia seed in one vegetarian capsule, along with 10 mg of vitamin B6 (from pyridoxine HCl) and 5 mg NE of niacin. Each bottle holds 60 capsules, and the serving is one a day. 5-HTP is the step right before serotonin, so it supports a balanced mood and restful sleep.†\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eThis one is for adults who want to look after their mood and their sleep with nutrition, without turning it into a project. One capsule, once a day, nothing to mix or measure. It's worth starting in your 30s and 40s, because steady moods and decent sleep are what everything else gets built on, including your plans for your 70s and 80s. Aging isn't optional. Getting old is.\u003c\/p\u003e\r\n\u003ch2\u003eWhy people take 5-HTP\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eSupports serotonin production.\u003c\/strong\u003e 5-HTP is the direct building block your body turns into serotonin, a chemical messenger that works in both the brain and the gut.†\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eSupports a balanced, positive mood.\u003c\/strong\u003e Serotonin is one of the messengers your brain uses to regulate mood.†\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eSupports restful sleep and a healthy sleep-wake cycle.\u003c\/strong\u003e Your body makes melatonin, the hormone that times sleep, out of serotonin.†\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eVitamin B6 for the conversion step.\u003c\/strong\u003e B6 helps your body make neurotransmitters, and the label lists it as an enzyme co-factor associated with serotonin production.†\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eNiacin for everyday energy metabolism.\u003c\/strong\u003e Niacin becomes NAD, a coenzyme your cells use to turn food into energy.†\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\r\n\u003ctable\u003e\r\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\r\n\u003ctbody\u003e\r\n\u003ctr\u003e\n\u003ctd\u003eNiacin\u003c\/td\u003e\n\u003ctd\u003e5 mg NE\u003c\/td\u003e\n\u003ctd\u003e31%\u003c\/td\u003e\n\u003c\/tr\u003e\r\n\u003ctr\u003e\n\u003ctd\u003eVitamin B6 (from pyridoxine HCl)\u003c\/td\u003e\n\u003ctd\u003e10 mg\u003c\/td\u003e\n\u003ctd\u003e588%\u003c\/td\u003e\n\u003c\/tr\u003e\r\n\u003ctr\u003e\n\u003ctd\u003e5-Hydroxytryptophan (from Griffonia simplicifolia seed)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e* (Daily Value not established)\u003c\/td\u003e\n\u003c\/tr\u003e\r\n\u003c\/tbody\u003e\r\n\u003c\/table\u003e\r\n\u003cp\u003eServing size is 1 vegetarian capsule, and each bottle holds 60 vegetarian capsules, a 60-day supply at the label's serving. Other ingredients, exactly as printed: Enhance™, vegetable cellulose (preservative-free, from capsule shell), deep mined calcium phosphate, cellulose, magnesium trisilicate, silica, and magnesium stearate. The label states: \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" It also says: \"Formulated with Enhance™ metabolite uptake enhancers. Contains citrus products.\"\u003c\/p\u003e\r\n\u003ch2\u003eHow 5-HTP works\u003c\/h2\u003e\r\n\u003ch3\u003e5-HTP (5-hydroxytryptophan), 100 mg from Griffonia simplicifolia seed\u003c\/h3\u003e\r\n\u003cp\u003eYour body makes serotonin in two steps. First, it takes tryptophan, an amino acid from the protein you eat, and converts it into 5-HTP. That first step is the slow one, the bottleneck that limits how fast serotonin gets made. Second, another enzyme turns 5-HTP into serotonin. Some of that serotonin later becomes melatonin, the hormone made by the pineal gland that helps run your sleep-wake cycle (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33375373\/\"\u003ea review of how 5-HTP is made and used in the body\u003c\/a\u003e). Taking 5-HTP hands your body the material for step two directly, past the bottleneck.†\u003c\/p\u003e\r\n\u003cp\u003eWhy Griffonia simplicifolia? The seeds of this African plant are the main source used to produce 5-HTP commercially, according to the same review.\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eWhat the research shows.\u003c\/strong\u003e In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18209781\/\"\u003ea small crossover study in 8 healthy adults\u003c\/a\u003e, 100 mg of 5-HTP at bedtime for 10 days raised urine levels of 5-HIAA, the main breakdown product of serotonin, to a median of 204 micromoles a day, compared with 18 on placebo. The spread between people was wide. In plain terms, the body takes it up and uses it. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38309227\/\"\u003ea 12-week trial in 30 adults averaging 66 years old\u003c\/a\u003e, blood serotonin rose in the group taking 100 mg a day, and the people in that group who started out as poor sleepers improved their overall sleep-quality score by week 12. Good sleepers didn't see a significant change.†\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eWhat it doesn't show.\u003c\/strong\u003e These are small studies. The 12-week trial compared 5-HTP with taking nothing, not with a placebo capsule. We didn't find large, long-term trials of 5-HTP in healthy adults in their 30s and 40s, and nobody can promise how it will feel for you. That's why we call this support, not a quick fix.\u003c\/p\u003e\r\n\u003ch3\u003eVitamin B6 (from pyridoxine HCl), 10 mg\u003c\/h3\u003e\r\n\u003cp\u003eVitamin B6 works as a coenzyme in more than 100 enzyme reactions, and it plays a part in making neurotransmitters (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB6-HealthProfessional\/\"\u003ethe NIH Office of Dietary Supplements vitamin B6 fact sheet\u003c\/a\u003e). Its active coenzyme form is pyridoxal 5'-phosphate (PLP). The label puts it this way: \"Enzyme co-factors B-6 and Niacin are associated with serotonin production.\"†\u003c\/p\u003e\r\n\u003cp\u003ePyridoxine HCl is the most common form of B6 in supplements, and according to the same NIH fact sheet, absorption from supplements doesn't differ much from one B6 form to another. Ten mg is 588% of the 1.7 mg Daily Value, and a tenth of the 100 mg a day upper limit set for adults.\u003c\/p\u003e\r\n\u003ch3\u003eNiacin, 5 mg NE\u003c\/h3\u003e\r\n\u003cp\u003eNiacin (vitamin B3) gets turned into NAD, a coenzyme that more than 400 enzymes rely on, mostly to pull usable energy out of carbohydrates, fats and protein (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\"\u003ethe NIH Office of Dietary Supplements niacin fact sheet\u003c\/a\u003e).† \"NE\" means niacin equivalents. Your body can make niacin from tryptophan, the same amino acid serotonin starts from, at about 60 mg of tryptophan for every 1 mg of niacin. Five mg is a modest 31% of the Daily Value, well under the 35 mg upper limit for added niacin and below the 30 to 50 mg of nicotinic acid that typically causes flushing.\u003c\/p\u003e\r\n\u003ch3\u003eEnhance™\u003c\/h3\u003e\r\n\u003cp\u003eEnhance™ is what the label calls \"metabolite uptake enhancers.\" The label doesn't break out what's in it, so we make no claims for it here. Note that the label also says \"Contains citrus products.\"\u003c\/p\u003e\r\n\u003ch2\u003eHow to take 5-HTP\u003c\/h2\u003e\r\n\u003cp\u003eLabel directions: \"One capsule daily, as a dietary supplement.\"\u003c\/p\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eThe label doesn't set a time of day, so pick one you'll remember. In the bedtime study above, people took their 100 mg at night.\u003c\/li\u003e\r\n\u003cli\u003eStay with the label's one capsule unless your practitioner says otherwise. 5-HTP can cause stomach upset that depends on the dose, and nausea and vomiting have been reported at doses above 100 mg (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33375373\/\"\u003ethe 5-HTP physiology and toxicology review\u003c\/a\u003e).\u003c\/li\u003e\r\n\u003cli\u003eGive it a few weeks. The sleep-score change in the trial above was reported at week 12, not overnight.\u003c\/li\u003e\r\n\u003cli\u003eIf you're scheduled for a 24-hour urine test for 5-HIAA, tell your practitioner you take 5-HTP, because it raises that number.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. That goes double if you take an antidepressant or any other medication that affects serotonin, because stacking them can push serotonin too high.\u003c\/p\u003e\r\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, the 5-HTP included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\/5-htp\"\u003eSee the certificates of analysis for this product\u003c\/a\u003e.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility keeps the formulators, the makers and the testers under one roof, and the owners work in the building too (they've run the place since 2017). We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\r\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\r\n\u003ch3\u003eHow much 5-HTP is in each capsule?\u003c\/h3\u003e\r\n\u003cp\u003eEach capsule has 100 mg of 5-HTP from Griffonia simplicifolia seed, plus 10 mg of vitamin B6 and 5 mg NE of niacin. One capsule is a serving, and the bottle holds 60.\u003c\/p\u003e\r\n\u003ch3\u003eWhen should I take 5-HTP, and with food or without?\u003c\/h3\u003e\r\n\u003cp\u003eWhenever suits you, because the label simply says one capsule daily. It doesn't specify food either way, so take it the way that sits well with your stomach.\u003c\/p\u003e\r\n\u003ch3\u003eHow long until I notice a difference?\u003c\/h3\u003e\r\n\u003cp\u003eThere's no set timeline, but think in weeks, not hours. In the 12-week trial above, the sleep-score change in poor sleepers was reported at week 12, and results varied from person to person.†\u003c\/p\u003e\r\n\u003ch3\u003eCan I take 5-HTP with Sleepy Sleep or melatonin?\u003c\/h3\u003e\r\n\u003cp\u003eYou can, and we sell 5-HTP with Sleepy Sleep and Relaxing Passion Flower as the \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calm-sleep-stack-sleepy-passion-ht\"\u003eCalm + Sleep Stack\u003c\/a\u003e, but count your total 5-HTP first. Each \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/natural-sleep-aid-herbal-support\"\u003eSleepy Sleep herbal sleep capsule\u003c\/a\u003e already contains 25 mg of 5-HTP and 1 mg of melatonin, and its label says one to two capsules 45 to 60 minutes before bed. Add one capsule of this 5-HTP and that's 125 to 150 mg of 5-HTP for the day, above the 100 mg level where the review cited above notes reports of nausea and vomiting. Melatonin, like our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/melatonin-3mg-timed-release\"\u003eMelatonin 3 mg Timed Release capsules\u003c\/a\u003e, is the sleep hormone itself, while 5-HTP sits further upstream as serotonin's building block. Check with your practitioner before combining them, especially if you take any medication.\u003c\/p\u003e\r\n\u003ch3\u003eIs 5-HTP safe to take with my medication?\u003c\/h3\u003e\r\n\u003cp\u003eAsk your healthcare practitioner first. 5-HTP raises serotonin, so it can add to the effect of antidepressants and other medications that affect serotonin, and too much serotonin is a real risk.\u003c\/p\u003e\r\n\u003ch3\u003eDoes 5-HTP contain common allergens?\u003c\/h3\u003e\r\n\u003cp\u003eThe label states \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives,\" and it notes \"Contains citrus products.\" If citrus is a concern for you, talk with your practitioner before using it.\u003c\/p\u003e\r\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\/5-htp\"\u003eLab reports for 5-HTP 100 mg\u003c\/a\u003e\u003c\/li\u003e\r\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calm-sleep-stack-sleepy-passion-ht\"\u003eCalm + Sleep Stack: 5-HTP with Sleepy Sleep and Relaxing Passion Flower\u003c\/a\u003e\u003c\/li\u003e\r\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/relaxation-supplement-passion-fl\"\u003eRelaxing Passion Flower lozenges with 50 mg passionflower extract\u003c\/a\u003e\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch2\u003eReferences\u003c\/h2\u003e\r\n\u003col\u003e\r\n\u003cli\u003eMaffei ME. 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology. Int J Mol Sci. 2020. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33375373\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\r\n\u003cli\u003eJoy T et al. Increase of urinary 5-hydroxyindoleacetic acid excretion but not serum chromogranin A following over-the-counter 5-hydroxytryptophan intake. Can J Gastroenterol. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18209781\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\r\n\u003cli\u003eSutanto CN et al. The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial. Clin Nutr. 2024. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38309227\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\r\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424577306,"sku":"015-A7002","price":19.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A7002REV00_ListingImage1.png?v=1742328134"},{"product_id":"bone-power-strontium","title":"Bone Power Strontium 350 mg – Healthy Bone Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eBone Power Strontium™ is a single-ingredient mineral supplement that gives you 350 mg of strontium, from strontium citrate, in each 2-capsule serving. A bottle holds 60 vegetarian capsules (30 servings), taken as one capsule twice a day and kept 2 hours apart from calcium products. It's made to promote strong, healthy bones as one part of your bone routine.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBone is living tissue. Your body is always clearing out old bone and laying down fresh bone in its place, and that rebuilding job runs for your whole life. Bone Power Strontium is for adults who already cover the basics (calcium, vitamin D, protein, and some walking or lifting) and want to add one more mineral to the mix. Start in your 30s and 40s, because the habits you build now are the ones your 70s and 80s get to keep.\u003c\/p\u003e\n\u003cp\u003eAging isn't optional. Getting old is. Strong bones are a big part of staying the person who still hikes, carries the groceries in one trip, and gets up off the floor without a second thought.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Bone Power Strontium\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrong, healthy bones.\u003c\/strong\u003e That's the statement printed on our label, and it's the whole job of this bottle.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA mineral your bones already recognize.\u003c\/strong\u003e Your body handles strontium much like calcium and builds it into bone mineral right alongside it.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStudied for its role in bone remodeling.\u003c\/strong\u003e In lab and animal research, strontium encourages the cells that build bone and slows the cells that clear old bone away.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFits the routine you already have.\u003c\/strong\u003e One mineral with one job, added to a routine of calcium, vitamin D3, vitamin K2 and weight-bearing exercise.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eStrontium (from strontium citrate)\u003c\/td\u003e\n\u003ctd\u003e350 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value Not Established. Serving size: 2 Vegetarian Capsules. Servings per container: 30. One active ingredient, no blends.\u003c\/p\u003e\n\u003cp\u003eOther ingredients: Vegetable cellulose (preservative-free, from capsule shell), magnesium trisilicate, magnesium stearate, and silica. The vegetable cellulose is the capsule shell itself. The label also states: \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow Bone Power Strontium works\u003c\/h2\u003e\n\u003ch3\u003eStrontium, calcium's chemical cousin\u003c\/h3\u003e\n\u003cp\u003eStrontium sits right below calcium on the periodic table, and your body handles the two in similar ways. Strontium competes with calcium for absorption in the gut, travels in the blood, and settles into the mineral crystals that make bone hard. In lab and small-animal studies it has a reputation for doing two things at once: encouraging osteoblasts, the cells that build bone, and holding back osteoclasts, the cells that break old bone down so it can be replaced, according to \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32395571\/\"\u003ea 2020 review of how strontium acts in bone\u003c\/a\u003e.†\u003c\/p\u003e\n\u003ch3\u003eWhy strontium citrate\u003c\/h3\u003e\n\u003cp\u003eStrontium has to be bound to something to fit in a capsule. The large human trials used strontium ranelate, a compound that was approved as a prescription drug in Europe and Australia but not in the United States or Canada. Strontium citrate (strontium bound to citric acid) is a form sold over the counter as a dietary supplement. The 350 mg on our label is the strontium itself, not the weight of the whole citrate compound.\u003c\/p\u003e\n\u003cp\u003eHow does citrate compare? In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22995463\/\"\u003ea small 8-week study in rats given strontium citrate or strontium ranelate\u003c\/a\u003e (19 female rats in all), both strontium groups ended up with far more strontium in their bones than the control group. The citrate group's levels were higher, but its doses also carried more strontium, and once the researchers adjusted for dose, the difference between the two forms was not significant. The same authors point out that the effects of strontium citrate on bone are still largely unknown. That's a rat study, not a human one, and we'd rather tell you that than round it up.\u003c\/p\u003e\n\u003ch3\u003eWhat the research does and doesn't show\u003c\/h3\u003e\n\u003cp\u003eThe lab and small-animal evidence on bone cells is strong. In people, the large trials of the prescription form suggest that bone-building effect may not carry over, and the 2020 review's authors propose that strontium may work mainly by being built into the bone mineral itself (Marx 2020). Those trials also used a different compound than this one, so their results can't simply be transferred to a strontium citrate supplement.\u003c\/p\u003e\n\u003cp\u003eOne more wrinkle worth knowing. Strontium atoms are heavier than calcium atoms, so bone that contains strontium looks denser on a DXA bone scan than it is. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10677790\/\"\u003eA lab study of how strontium changes DXA readings\u003c\/a\u003e, using mixtures of calcium and strontium bone mineral, found the scan reads about 10% high for every 1% of the mineral's calcium swapped for strontium, and the correction was the same on every scanner model tested. So scan numbers taken while you use strontium need that context.\u003c\/p\u003e\n\u003ch3\u003eWhy the 2-hour gap from calcium\u003c\/h3\u003e\n\u003cp\u003eStrontium and calcium compete for absorption. Our label puts it plainly: take it 2 hours before or after calcium products, \"as it will interfere with absorption of calcium.\" Research in healthy adults shows the other side of the same tug-of-war. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12075684\/\"\u003eA pooled analysis of strontium absorption in healthy adults\u003c\/a\u003e estimated that people absorb about 22% of the strontium they swallow on average (typically somewhere between 11% and 46%), and that absorption drops when calcium intake is very high and rises when it is very low. Spacing the two apart gives each one its own turn.\u003c\/p\u003e\n\u003ch2\u003eHow to take Bone Power Strontium\u003c\/h2\u003e\n\u003cp\u003eLabel directions: \"One capsule twice daily, as a dietary supplement. Should be taken 2 hours before or after calcium products, as it will interfere with absorption of calcium.\" Two capsules a day is one serving, so a bottle is a 30-day supply.\u003c\/p\u003e\n\u003cp\u003eOne easy rhythm: calcium with breakfast and dinner, one strontium capsule mid-morning and one at bedtime. Big calcium-rich meals are worth spacing out too, since very high calcium intake cuts into strontium absorption. Bone changes slowly, so this is a take-it-every-day habit, not something you'll feel next week.\u003c\/p\u003e\n\u003cp\u003eLabel warning: \"Not to be used by children or adolescents, as it can alter growing bones. If pregnant, considering pregnancy, or lactating, consult a health care practitioner prior to use.\" Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. If you get bone density scans, tell whoever orders them that you take strontium.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, the strontium citrate in this bottle included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Bone Power Strontium we make gets its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley. Our formulators, makers and testers work under one roof in a UL-certified cGMP facility, and the owners work in the building too (owner-run since 2017), so the people who answer for every lot are just down the hall from it. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much strontium is in Bone Power Strontium?\u003c\/h3\u003e\n\u003cp\u003eEach 2-capsule serving has 350 mg of strontium from strontium citrate. That number is the strontium itself, not the whole citrate compound. There's no Daily Value for strontium, which is why the label shows an asterisk instead of a percentage.\u003c\/p\u003e\n\u003ch3\u003eWhen should I take it, and does it need food?\u003c\/h3\u003e\n\u003cp\u003eTake one capsule twice a day, 2 hours before or after any calcium products, as the label directs. The label doesn't call for food, so the timing around calcium is the part that matters. Mid-morning and bedtime are easy slots for most schedules.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Nice Bones, Bones + K2 or Calcium Citrate?\u003c\/h3\u003e\n\u003cp\u003eYes, just not at the same time. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/nice-bones\"\u003eNice Bones calcium, magnesium and vitamin D tablets\u003c\/a\u003e, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/bones-k2-comprehensive-bone-supp\"\u003eBones + K2 with marine-algae calcium, D3 and K2\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calcium-citrate-60ct\"\u003eCalcium Citrate 250 mg capsules\u003c\/a\u003e all contain calcium, so keep them 2 hours apart from Bone Power Strontium.\u003c\/p\u003e\n\u003ch3\u003eWill strontium change a bone density scan?\u003c\/h3\u003e\n\u003cp\u003eIt can. Strontium is heavier than calcium, so bone that contains it reads denser on a DXA scan than it is. The lab study above put the overestimate at about 10% for every 1% of bone calcium replaced by strontium. Tell whoever orders your scan that you take strontium so they can read the numbers in context.\u003c\/p\u003e\n\u003ch3\u003eHow long before I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eYou probably won't feel anything, and that's normal. Bone remodels slowly, over months and years, so think of strontium as a long-term habit, not a quick fix.\u003c\/p\u003e\n\u003ch3\u003eIs strontium citrate the same as prescription strontium?\u003c\/h3\u003e\n\u003cp\u003eNo. The prescription form used in the large trials is strontium ranelate, a different compound that isn't approved in the United States. Strontium citrate is a dietary supplement form, and results from ranelate can't be assumed to apply to it.\u003c\/p\u003e\n\u003ch3\u003eIs it safe with my medications?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first if you take any medication, have a medical condition, or are pregnant, considering pregnancy, or nursing. Bone Power Strontium is not for children or adolescents, per the label warning.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/everyday-liquid-sunshine-2-d3-k2\"\u003eEveryday Liquid Sunshine 2, vitamin D3 + K2 drops\u003c\/a\u003e, which list no calcium on their Supplement Facts, so the label's calcium spacing doesn't apply\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eMarx D et al. A review of the latest insights into the mechanism of action of strontium in bone. Bone Reports. 2020. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32395571\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWohl GR et al. Accumulation of bone strontium measured by in vivo XRF in rats supplemented with strontium citrate and strontium ranelate. Bone. 2013. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22995463\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eNielsen SP et al. Influence of strontium on bone mineral density and bone mineral content measurements by dual X-ray absorptiometry. Journal of Clinical Densitometry. 1999. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10677790\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eApostoaei AI. Absorption of strontium from the gastrointestinal tract into plasma in healthy human adults. Health Physics. 2002. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12075684\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424544538,"sku":"015-A5007","price":25.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A5007_REV00_Necktag.png?v=1747256467"},{"product_id":"adrenal-support-60-vegetarian","title":"Adrenal Support – Adaptogens for Occasional Stress | 60 Vegetarian Tablets","description":"\u003cp\u003e\u003cstrong\u003eAdrenal Support is a vegetarian tablet that combines a 425 mg herbal blend of rhodiola, ashwagandha, eleuthero, schisandra, wild yam and nettle with 500 mg of pantothenic acid (vitamin B5), 20 mg of vitamin B6 and 50 mg of vitamin C in every 2-tablet serving. Each bottle holds 60 tablets. It's made to support a healthy response to occasional stress.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eYour 30s and 40s are when the calendar fills up: work, kids, aging parents, and the 6 a.m. workout you swore you'd keep. It's also the right time to build the habits that carry you into your 70s and 80s. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003cp\u003eAdrenal Support is for adults who want one simple daily step for how their body handles everyday pressure, alongside sleep, food, movement and saying no to the fourth committee.†\u003c\/p\u003e\n\u003ch2\u003eWhy people take Adrenal Support\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTo support a healthy response to occasional stress, with four herbs researchers call adaptogens: rhodiola, ashwagandha, eleuthero and schisandra.†\u003c\/li\u003e\n\u003cli\u003eTo support focus and mental performance on demanding days.†\u003c\/li\u003e\n\u003cli\u003eTo support normal energy metabolism with 500 mg of pantothenic acid and 20 mg of vitamin B6.†\u003c\/li\u003e\n\u003cli\u003eTo get vitamin C, a nutrient your adrenal glands hold in high concentration and use in normal hormone production.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin C\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003e55%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B6 (from pyridoxine HCl)\u003c\/td\u003e\n\u003ctd\u003e20 mg\u003c\/td\u003e\n\u003ctd\u003e1,176%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePantothenic Acid (from d-calcium pantothenate)\u003c\/td\u003e\n\u003ctd\u003e500 mg\u003c\/td\u003e\n\u003ctd\u003e10,000%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eProprietary Herbal Blend: Rhodiola Root Extract (\u003cem\u003eRhodiola rosea\u003c\/em\u003e, standardized to 1% salidrosides), Ashwagandha Root Extract (\u003cem\u003eWithania somnifera\u003c\/em\u003e, standardized to 2.5% withanolides), Wild Yam Root 10:1 Extract (\u003cem\u003eDioscorea\u003c\/em\u003e spp.), Schizandra Berry (\u003cem\u003eSchisandra chinensis\u003c\/em\u003e), \u003cem\u003eEleutherococcus senticosus\u003c\/em\u003e Root 50:1 Extract, and Stinging Nettle Leaf (\u003cem\u003eUrtica dioica\u003c\/em\u003e, organic, freeze-dried)\u003c\/td\u003e\n\u003ctd\u003e425 mg\u003c\/td\u003e\n\u003ctd\u003e* Daily Value not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 2 vegetarian tablets. Servings per container: 30. Other ingredients: Cellulose, L-leucine, silica, and chlorophyll. The label states: \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow Adrenal Support works\u003c\/h2\u003e\n\u003cp\u003e\"Adaptogen\" is what researchers call herbs studied for helping the body keep its balance under stress. A review of that research describes adaptogens as working through your main stress-response system (the hypothalamic-pituitary-adrenal, or HPA, axis) and stress messengers like cortisol and the protective protein Hsp70, with much of the mechanism work done in cells and animals (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27713248\/\"\u003ePanossian and Wikman's review of adaptogen mechanisms\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eOne honest note: the six herbs come as a 425 mg proprietary blend, so the label doesn't list how much of each herb is in a serving. That means we can't tell you this tablet matches the doses used in the studies below, and we won't pretend it does.\u003c\/p\u003e\n\u003ch3\u003eRhodiola root extract (standardized to 1% salidrosides)\u003c\/h3\u003e\n\u003cp\u003eSalidroside is one of the compounds rhodiola extracts are standardized to, and \"standardized to 1%\" means each lot of extract is checked to carry that level. A systematic review of 11 placebo-controlled trials (six on physical performance, four on mental performance) concluded rhodiola may help both, with only a few mild side effects, but noted that most findings hadn't been independently repeated (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21036578\/\"\u003ea systematic review of rhodiola trials\u003c\/a\u003e).†\u003c\/p\u003e\n\u003ch3\u003eAshwagandha root extract (standardized to 2.5% withanolides)\u003c\/h3\u003e\n\u003cp\u003eAshwagandha is an herb with a long history of traditional use, and this blend uses an extract of its root. Withanolides are the compounds its extracts are measured by, and ours carries 2.5%. In a 60-day trial, 60 healthy adults who reported high stress took 240 mg of a standardized ashwagandha extract or a placebo once a day. The ashwagandha group had a larger drop in morning cortisol than the placebo group, and no side effects were reported. It was a small study, and the authors called for larger ones (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31517876\/\"\u003ea 60-day ashwagandha trial in stressed, healthy adults\u003c\/a\u003e).†\u003c\/p\u003e\n\u003ch3\u003eEleuthero and schisandra\u003c\/h3\u003e\n\u003cp\u003eOur eleuthero (\u003cem\u003eEleutherococcus senticosus\u003c\/em\u003e) is a 50:1 root extract, made from roughly 50 parts root concentrated into 1 part extract. The schisandra is listed on the label as the berry itself (\u003cem\u003eSchisandra chinensis\u003c\/em\u003e). Researchers often study these two with rhodiola as a trio. In a pilot trial, 40 healthy women who said they'd felt stressed for a long time took a single 270 mg tablet of a fixed rhodiola, schisandra and eleuthero combination or a placebo. Two hours later, the combination group scored better on attention, speed and accuracy during a demanding mental task (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20374974\/\"\u003ea single-dose trial of a rhodiola, schisandra and eleuthero blend\u003c\/a\u003e). That was one dose of a different product, so read it as a promising signal, not a promise.†\u003c\/p\u003e\n\u003ch3\u003ePantothenic acid (vitamin B5), 500 mg\u003c\/h3\u003e\n\u003cp\u003eYour body uses pantothenic acid to make coenzyme A, a molecule needed to build and break down fats and for many other reactions in your cells. Ours is d-calcium pantothenate, a common supplemental form (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/PantothenicAcid-HealthProfessional\/\"\u003eNIH fact sheet on pantothenic acid\u003c\/a\u003e). The Daily Value is 5 mg, which is why 500 mg reads as 10,000%.†\u003c\/p\u003e\n\u003ch3\u003eVitamin B6, 20 mg\u003c\/h3\u003e\n\u003cp\u003eThis is pyridoxine HCl, the most common form of B6 in supplements. In your body, B6 works through its active coenzyme forms (PLP and PMP), which take part in more than 100 enzyme reactions, mostly in protein metabolism, and B6 also helps make neurotransmitters (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB6-HealthProfessional\/\"\u003eNIH fact sheet on vitamin B6\u003c\/a\u003e). Twenty milligrams is 1,176% of the Daily Value and under the 100 mg a day upper limit the U.S. Food and Nutrition Board set for adults.†\u003c\/p\u003e\n\u003ch3\u003eVitamin C, 50 mg\u003c\/h3\u003e\n\u003cp\u003eYour adrenal glands hold some of the highest vitamin C levels in your body. Vitamin C is a cofactor for making the catecholamines (the adrenaline family) and for steroid hormone production in the adrenal glands, based mostly on cell and animal research (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15666839\/\"\u003ea review of vitamin C's role in the adrenal glands\u003c\/a\u003e). Fifty milligrams is 55% of the Daily Value.†\u003c\/p\u003e\n\u003ch3\u003eWild yam root and nettle leaf\u003c\/h3\u003e\n\u003cp\u003eWild yam root (a 10:1 extract) and organic, freeze-dried stinging nettle leaf round out the blend as traditional herbs. Human research on either one for stress is thin, so we won't oversell them.\u003c\/p\u003e\n\u003ch2\u003eHow to take Adrenal Support\u003c\/h2\u003e\n\u003cp\u003eThe label says: \"One to two tablets, as a dietary supplement.\" The amounts in the table above are for a 2-tablet serving.\u003c\/p\u003e\n\u003cp\u003eThe label doesn't call for food, so take it at a time you'll remember. Taking other supplements? Add up the vitamin B6 across all of them (see the FAQ).\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Each lot of Adrenal Support has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility keeps the formulators, the makers and the testers under one roof. The company has been owner-run since 2017, and the owners work in the building. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many Adrenal Support tablets should I take?\u003c\/h3\u003e\n\u003cp\u003eFollow the label: \"One to two tablets, as a dietary supplement.\" The Supplement Facts amounts are for 2 tablets, and the bottle holds 60 tablets, or 30 servings.\u003c\/p\u003e\n\u003ch3\u003eDoes Adrenal Support contain caffeine?\u003c\/h3\u003e\n\u003cp\u003eNo, caffeine isn't on the label. Each serving is three vitamins, the six-herb blend, and four other ingredients: cellulose, L-leucine, silica and chlorophyll.\u003c\/p\u003e\n\u003ch3\u003eIsn't 10,000% of the Daily Value of pantothenic acid a lot?\u003c\/h3\u003e\n\u003cp\u003eIt's a big percentage on a small baseline. The Daily Value is just 5 mg. No upper limit has been set because there are no reports of pantothenic acid toxicity in humans, and the mild stomach upset reported with very large doses came at around 10 grams a day, twenty times the 500 mg in a serving.\u003c\/p\u003e\n\u003ch3\u003eCan I take Adrenal Support with your B-Complex?\u003c\/h3\u003e\n\u003cp\u003eCheck with your practitioner first, because of vitamin B6. A serving of Adrenal Support has 20 mg and a capsule of our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/b-good-com-vitamin-b-complex\"\u003eB-Complex vitamin formula\u003c\/a\u003e has 100 mg, which adds up to 120 mg a day. The U.S. upper limit for adults from all sources is 100 mg a day. Our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/b12-sublingual-essential-trio\"\u003eB-12 Essential Trio liquid\u003c\/a\u003e adds 4 mg of B6 per serving.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with CortiResponse?\u003c\/h3\u003e\n\u003cp\u003eAsk your practitioner before combining them. Both contain ashwagandha (\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/cortiresponse-stress-mood-support\"\u003eCortiResponse, our ashwagandha and L-theanine formula\u003c\/a\u003e, lists 100 mg of ashwagandha root per serving), and one may be enough.\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice anything?\u003c\/h3\u003e\n\u003cp\u003eWe can't promise a timeline. The three-herb trial above measured results two hours after one dose, and the ashwagandha trial after 60 days, both with different products at known doses.\u003c\/p\u003e\n\u003ch3\u003eIs Adrenal Support safe with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner, and bring the bottle. Herbs aren't harmless just because they grow in the ground. You can also look up combinations in our \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/tools\/interaction-checker\"\u003esupplement and medication interaction checker\u003c\/a\u003e first.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/single-bottle-solution-what-is-it-and-why-do-we-put-it-on-our-premium-bottles\"\u003eWhat \"Single Bottle Solution\" on our label means\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/natural-sleep-aid-herbal-support\"\u003eSleepy Sleep, an herbal formula for the evening half of your routine\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003ePanossian A et al. Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress-Protective Activity. Pharmaceuticals (Basel). 2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27713248\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHung SK et al. The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials. Phytomedicine. 2011. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21036578\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eLopresti AL et al. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31517876\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAslanyan G et al. Double-blind, placebo-controlled, randomised study of single dose effects of ADAPT-232 on cognitive functions. Phytomedicine. 2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20374974\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003ePatak P et al. Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla. Endocr Res. 2004. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15666839\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424511770,"sku":"015-M1000","price":29.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1000_REV04_Necktag.png?v=1738257990"},{"product_id":"parasite-cleanse-travel-support","title":"Para Response – Herbal Intestinal Support \u0026 Cleanse | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003ePara Response is an herbal intestinal support formula in 60 vegetarian capsules. Each capsule has 100 mg each of wormwood flower and leaf, black walnut green hull and cloves, plus 50 mg each of deodorized garlic, butternut root bark, buckhorn bark (Rhamnus frangula) and pau d'arco bark. It's taken in short, structured cycles to support intestinal balance and regularity.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIt's for people who like the old-school, bitter-herb approach to digestion and want it in a defined routine, including people whose routines get scrambled by trips, unfamiliar foods and irregular meals. It isn't an everyday product: the label says daily for up to two months, then two months off, up to three times a year.\u003c\/p\u003e\n\u003cp\u003eCandidly, this is a traditional herbal formula. No clinical trial has tested Para Response or this exact combination, and most of what's known about each herb comes from centuries of use and lab studies.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Para Response\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIntestinal balance.\u003c\/strong\u003e Wormwood, black walnut green hull and cloves (100 mg each) are a traditional trio for supporting a balanced intestinal environment.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegularity.\u003c\/strong\u003e Buckhorn bark (Rhamnus frangula) and butternut root bark are traditional botanicals for supporting regular, comfortable bowel movements.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNormal digestion.\u003c\/strong\u003e Wormwood is among the most bitter herbs there is, and bitter herbs have long been used to support normal digestion.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA routine with an end date.\u003c\/strong\u003e A two-week ramp-up and built-in breaks make it a clear, short-term plan for intestinal support.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eWormwood Flower and Leaf (\u003cem\u003eArtemisia absinthium\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBlack Walnut Green Hull (\u003cem\u003eJuglans nigra\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCloves (\u003cem\u003eSyzygium aromaticum\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGarlic (deodorized, from \u003cem\u003eAllium sativum\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eButternut Root Bark (\u003cem\u003eJuglans cinerea\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBuckhorn Bark (\u003cem\u003eRhamnus frangula\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePau D'Arco (\u003cem\u003eTabebuia heptaphylla\u003c\/em\u003e bark)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established. Serving size: 1 vegetarian capsule. Each bottle holds 60 vegetarian capsules, so that's 60 servings. Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), arabinogalactan (from \u003cem\u003eLarix occidentalis\u003c\/em\u003e), organic rice extract, and organic rice concentrate.\u003c\/p\u003e\n\u003cp\u003eThat's 500 mg of herbs per capsule. At the label's full amount (two capsules three times daily), you get 600 mg each of wormwood, black walnut green hull and cloves a day.\u003c\/p\u003e\n\u003ch2\u003eHow Para Response works\u003c\/h2\u003e\n\u003ch3\u003eWormwood flower and leaf (100 mg)\u003c\/h3\u003e\n\u003cp\u003eWormwood (\u003cem\u003eArtemisia absinthium\u003c\/em\u003e) is a silvery daisy-family herb and one of the most bitter plants in herbalism, thanks mainly to compounds called sesquiterpene lactones such as absinthin. European and Asian traditional medicine have used it for the digestive tract for centuries, according to \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32825178\/\"\u003ea 2020 review of wormwood's chemistry and traditional uses\u003c\/a\u003e. The label lists the flower and leaf, not the concentrated essential oil. Thujone, the main compound behind wormwood's safety cautions, is found in that oil, and the herb carries some of the oil too. The same review notes thujone levels in the oil vary widely from plant to plant, so respect the label's on-and-off schedule.\u003c\/p\u003e\n\u003cp\u003eBitter tastes set off reflexes that researchers think help circulation keep up with digestion after a meal. The honest part: in healthy adults, tasting wormwood triggered a measurable reflex response, but wormwood in a capsule didn't trigger it during the stomach phase (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26074998\/\"\u003eresearch on how bitters act in healthy adults\u003c\/a\u003e). A capsule isn't a sip of bitters, and nobody has tested this blend in people.\u003c\/p\u003e\n\u003ch3\u003eBlack walnut green hull (100 mg)\u003c\/h3\u003e\n\u003cp\u003eThis is the green outer husk around the black walnut (\u003cem\u003eJuglans nigra\u003c\/em\u003e), not the nut you'd bake with. The husk contains phenolic compounds, and husk extracts showed antioxidant activity in \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28265357\/\"\u003ea lab study of black walnut husk antioxidants\u003c\/a\u003e. That's test-tube chemistry, not a human trial: it's here as part of the traditional recipe for intestinal balance.†\u003c\/p\u003e\n\u003ch3\u003eCloves (100 mg)\u003c\/h3\u003e\n\u003cp\u003eCloves are the dried flower buds of \u003cem\u003eSyzygium aromaticum\u003c\/em\u003e, the same spice in your pumpkin pie. They're one of the richest plant sources of phenolic compounds, including eugenol, and have been used for centuries as a food preservative and in traditional herbal practice (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25182278\/\"\u003ea review of clove's chemistry and uses\u003c\/a\u003e). Most clove research is lab work, so here cloves play their traditional role: a warming, aromatic partner to the bitter herbs.\u003c\/p\u003e\n\u003ch3\u003eDeodorized garlic (50 mg)\u003c\/h3\u003e\n\u003cp\u003eGarlic (\u003cem\u003eAllium sativum\u003c\/em\u003e) has a long history in traditional herbal formulas, and the deodorized form is easier on your breath. At 50 mg a capsule it's a supporting player, and we won't dress it up as more.\u003c\/p\u003e\n\u003ch3\u003eBuckhorn bark, butternut root bark and pau d'arco (50 mg each)\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eRhamnus frangula\u003c\/em\u003e, also called alder buckthorn or frangula, is a shrub whose bark contains hydroxyanthracene compounds. Botanicals with these compounds, including cascara, senna and rhubarb, have long been used for their laxative properties, and researchers have also raised safety questions about them (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41441021\/\"\u003ea 2025 analysis of frangula and related botanicals\u003c\/a\u003e), another reason to follow the label's schedule. At 50 mg a capsule, it's there to support regularity, not to run the show.†\u003c\/p\u003e\n\u003cp\u003eButternut (\u003cem\u003eJuglans cinerea\u003c\/em\u003e), or white walnut, is a North American cousin of black walnut whose root bark has a long folk history as a gentle aid to regularity. Pau d'arco is the bark of a South American tree used in that region's traditional herbal practice. There's very little human research on either, so think of them as part of the traditional recipe.\u003c\/p\u003e\n\u003ch2\u003eHow to take Para Response\u003c\/h2\u003e\n\u003cp\u003eThe label's directions, word for word: \"As a dietary supplement, start with one capsule three times daily. After two weeks use two capsules three times daily for up to two months. Discontinue use for two months.\" And: \"Not for continuous use. Can use daily for up to two months. Can repeat use up to three times per year.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBottle math.\u003c\/strong\u003e At three capsules a day, a 60-capsule bottle lasts 20 days; at six a day, 10 days. A full cycle takes more than one bottle, so plan ahead.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eListen to your gut.\u003c\/strong\u003e Buckhorn bark (frangula) encourages bowel movement. If you get loose or watery stools or cramping, stop taking it and check with your healthcare practitioner.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDaisy-family plants.\u003c\/strong\u003e Wormwood is in the daisy family, so if ragweed, chamomile or marigold give you trouble, ask your practitioner first.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eLabel warnings:\u003c\/strong\u003e \"WARNING: Not recommended while pregnant or lactating unless directed by health care practitioner.\" And: \"WARNING: This product can expose you to chemicals including Lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.\"\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, from the wormwood to the cloves, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Each production lot of Para Response has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e That's a farm town of about 3,500 people in the Willamette Valley. Para Response is made in our UL-certified cGMP facility, where the formulators, the makers and the testers all work under one roof. The owners work in the building too, and have run the place since 2017. We've been making supplements in Oregon since 1974, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow do I take Para Response, and for how long?\u003c\/h3\u003e\n\u003cp\u003eOne capsule three times a day for two weeks, then two capsules three times a day for up to two months, then two months off. The label says it's not for continuous use and allows up to three cycles a year. No research on this formula says how soon you'll notice anything.\u003c\/p\u003e\n\u003ch3\u003eShould I take Para Response with food?\u003c\/h3\u003e\n\u003cp\u003eThe label doesn't say, so it's your call. One dose with each meal is an easy way to remember three a day. If the capsules feel harsh on an empty stomach, take them with food. If they still bother you, stop and ask your practitioner.\u003c\/p\u003e\n\u003ch3\u003eCan I take Para Response with other Mt. Angel products?\u003c\/h3\u003e\n\u003cp\u003eYou can, though no one has studied these combinations, so run your full routine by your practitioner. Some people pair it with \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/3-in-1-probiotic-fusion\"\u003e3-in-1 Probiotic Fusion\u003c\/a\u003e or \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/super-enzymes-plus\"\u003eSuper Enzymes+, our digestive enzyme formula\u003c\/a\u003e. They cover different parts of digestion; they aren't a tested stack.\u003c\/p\u003e\n\u003ch3\u003eIs Para Response safe if I'm pregnant, nursing or taking medication?\u003c\/h3\u003e\n\u003cp\u003eThe label says it's not recommended while pregnant or lactating unless your health care practitioner directs it. If you take any medication or have a medical condition, ask your practitioner before you start.\u003c\/p\u003e\n\u003ch3\u003eIs Para Response a substitute for medical care when I travel?\u003c\/h3\u003e\n\u003cp\u003eNo. It's a dietary supplement that supports intestinal balance and regularity, not a medicine.† Follow standard food and water precautions when you travel. If you have severe, bloody or lasting digestive symptoms, a fever, or unexplained weight loss, see a healthcare practitioner instead of reaching for a supplement.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/digestive\/digestive-health-and-the-gut-microbiome\"\u003eWhat the gut microbiome is and why it matters\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/single-bottle-solution-what-is-it-and-why-do-we-put-it-on-our-premium-bottles\"\u003eWhat \"Single Bottle Solution\" on our label means\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/our-approach-to-formulation\"\u003eHow our formulators decide which ingredients go together\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eSzopa A et al. Artemisia absinthium L.-Importance in the History of Medicine, the Latest Advances in Phytochemistry and Therapeutical, Cosmetological and Culinary Uses. Plants (Basel). 2020. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32825178\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eMcMullen MK et al. Bitters: Time for a New Paradigm. Evid Based Complement Alternat Med. 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26074998\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWenzel J et al. Antioxidant potential of Juglans nigra, black walnut, husks extracted using supercritical carbon dioxide with an ethanol modifier. Food Sci Nutr. 2016. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28265357\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCortés-Rojas DF et al. Clove (Syzygium aromaticum): a precious spice. Asian Pac J Trop Biomed. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25182278\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eNezi P et al. Untargeted Metabolomics for Profiling of Cascara, Senna, Rhubarb, and Frangula Metabolites. Metabolites. 2025. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41441021\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424446234,"sku":"015-M1015","price":35.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1015REV04_ListingImage1.png?v=1738258057"},{"product_id":"natural-allergy-solution-quercetin","title":"Quercetin Nettle+ – Immune System Support | 60 Vegetarian Tablets","description":"\u003cp\u003e\u003cstrong\u003eQuercetin Nettle+ is a daily immune support supplement with 1,000 mg of quercetin, 100 mg of freeze-dried stinging nettle leaf, 150 mg of bromelain, 250 mg of vitamin C, 200 mg of pantothenic acid (vitamin B5) and 66 mg of magnesium in every 3-tablet serving. Each bottle holds 60 vegetarian tablets, and the formula supports the immune system.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIt's for adults who want immune support built around quercetin, the plant flavonoid in apples, onions and capers, at an amount above what a typical diet provides.† If you're in your 30s or 40s and already working on sleep, training and what's on your plate, this is the easy part: a few tablets a day, every amount on the label.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Quercetin Nettle+\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTo support the immune system, the job printed on the bottle.†\u003c\/li\u003e\n\u003cli\u003e250 mg of vitamin C (277% of the Daily Value), which supports the normal work of immune cells and is one of the body's important antioxidants.†\u003c\/li\u003e\n\u003cli\u003ePantothenic acid (vitamin B5) helps your body make coenzyme A, which it uses to turn food into energy.†\u003c\/li\u003e\n\u003cli\u003eMagnesium helps more than 300 enzyme systems do their jobs, including ones behind normal muscle and nerve function.†\u003c\/li\u003e\n\u003cli\u003e1,000 mg of quercetin per serving, plus freeze-dried nettle leaf and bromelain.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin C (from 336 mg magnesium ascorbate)\u003c\/td\u003e\n\u003ctd\u003e250 mg\u003c\/td\u003e\n\u003ctd\u003e277%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePantothenic Acid (from 234 mg d-calcium pantothenate)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003e4,000%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium (from magnesium ascorbate)\u003c\/td\u003e\n\u003ctd\u003e66 mg\u003c\/td\u003e\n\u003ctd\u003e15%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eQuercetin\u003c\/td\u003e\n\u003ctd\u003e1,000 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBromelain 1200 GDU\/g\u003c\/td\u003e\n\u003ctd\u003e150 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStinging Nettle Leaf (freeze dried \u003cem\u003eUrtica dioica\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 3 vegetarian tablets. Servings per container: 20. Other ingredients: Cellulose, organic rice concentrate, rice extract, and palm kernel extract. The label states: \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow Quercetin Nettle+ works\u003c\/h2\u003e\n\u003ch3\u003eQuercetin: 1,000 mg per serving\u003c\/h3\u003e\n\u003cp\u003eQuercetin is a flavonoid, one of the pigments that color apples, onions and berries. Supplements commonly provide up to 1,000 mg a day, which \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29127724\/\"\u003ea safety review of quercetin supplements\u003c\/a\u003e notes is more than people usually get from food. One serving here is 1,000 mg.\u003c\/p\u003e\n\u003cp\u003eDoes it get absorbed? Yes. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19947898\/\"\u003ea 12-week randomized, double-blind trial in 1,002 adults aged 18 to 85\u003c\/a\u003e, people taking 500 or 1,000 mg of quercetin a day (with 125 or 250 mg of vitamin C) saw blood quercetin rise in step with the dose. The 1,000 mg plus 250 mg pairing matches one serving here. What it doesn't show: the trial found no change in several blood measures of oxidative stress and antioxidant capacity. So quercetin at this amount reaches your bloodstream, and what that means for healthy adults is still being worked out.\u003c\/p\u003e\n\u003cp\u003eMuch of the research on quercetin and immune cells comes from lab dishes and animals, which can't tell you what a tablet does in a person, so we don't make claims from it.\u003c\/p\u003e\n\u003ch3\u003eVitamin C: 250 mg from magnesium ascorbate\u003c\/h3\u003e\n\u003cp\u003eYour body can't make vitamin C, so it has to come from food or supplements. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29099763\/\"\u003eA review of vitamin C and immune function\u003c\/a\u003e describes how immune cells such as neutrophils collect it, and how it supports the normal work of both the first-response (innate) and targeted (adaptive) sides of the immune system.†\u003c\/p\u003e\n\u003cp\u003eMagnesium ascorbate, a mineral salt of vitamin C, is less acidic than plain ascorbic acid and supplies the magnesium too. We won't oversell it: the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminC-HealthProfessional\/\"\u003eNIH vitamin C fact sheet\u003c\/a\u003e notes that the few human studies comparing forms mostly found similar blood levels.\u003c\/p\u003e\n\u003ch3\u003ePantothenic acid: 200 mg of vitamin B5\u003c\/h3\u003e\n\u003cp\u003eYour body uses pantothenic acid to make coenzyme A, a molecule needed to build and break down fats and for many other reactions (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/PantothenicAcid-HealthProfessional\/\"\u003eNIH pantothenic acid fact sheet\u003c\/a\u003e). In plain terms, B5 helps turn the food you eat into energy (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/PantothenicAcid-Consumer\/\"\u003eNIH consumer guide to pantothenic acid\u003c\/a\u003e).† The form, d-calcium pantothenate, is the most common one in supplements.\u003c\/p\u003e\n\u003cp\u003eYes, 200 mg is 4,000% of the Daily Value. No upper limit has been set because there are no reports of pantothenic acid toxicity in humans at high intakes; mild stomach upset has been reported at about 10 grams a day. Research on B5 at this amount in healthy adults is thin, so we don't claim 200 mg does anything specific.\u003c\/p\u003e\n\u003ch3\u003eMagnesium: 66 mg\u003c\/h3\u003e\n\u003cp\u003eMagnesium is a cofactor in more than 300 enzyme systems, including ones involved in muscle and nerve function and energy production (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Magnesium-HealthProfessional\/\"\u003eNIH magnesium fact sheet\u003c\/a\u003e).† At 15% of the Daily Value it's a modest top-up. Even six tablets give 132 mg, under the 350 mg adult upper limit for magnesium from supplements.\u003c\/p\u003e\n\u003ch3\u003eBromelain: 150 mg at 1200 GDU\/g\u003c\/h3\u003e\n\u003cp\u003eBromelain is a group of protein-digesting enzymes from pineapple stems. \"1200 GDU\/g\" is its activity rating in gelatin digesting units, so a serving delivers about 180 GDU. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9252520\/\"\u003eA study in 19 healthy men\u003c\/a\u003e found a small amount of bromelain reached the bloodstream intact and partly active, but at 3 grams a day, 20 times one serving here. You'll read online that bromelain helps quercetin absorb. We haven't found a human study showing that, so we don't claim it.\u003c\/p\u003e\n\u003ch3\u003eStinging nettle leaf: 100 mg, freeze-dried\u003c\/h3\u003e\n\u003cp\u003eStinging nettle (\u003cem\u003eUrtica dioica\u003c\/em\u003e) is the plant that gets your ankles on a hike. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36014458\/\"\u003eA 2022 review of stinging nettle's composition\u003c\/a\u003e notes the leaves are rich in bioactive compounds, and lists constituents such as flavonoids (including rutin and kaempferol, close relatives of quercetin), phenolic acids and carotenoids. Freeze-drying pulls the water out at low temperature instead of with heat. The review's authors call for more detailed clinical studies, so we make no claims for nettle here.\u003c\/p\u003e\n\u003ch2\u003eHow to take Quercetin Nettle+\u003c\/h2\u003e\n\u003cp\u003eThe label says: \"Three to six tablets daily, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eThree tablets is one serving. Six is two: 2,000 mg of quercetin, 500 mg of vitamin C (well under the 2,000 mg adult upper limit), 400 mg of pantothenic acid, 132 mg of magnesium, 300 mg of bromelain and 200 mg of nettle leaf. The label doesn't name a time or say to take it with food, so pick a time you'll stick with.\u003c\/p\u003e\n\u003cp\u003eAn honest note on the top of the range: the safety review found side effects were rare and mild in human quercetin studies, but there isn't adequate data on 1,000 mg a day or more for longer than 12 weeks. If you plan to stay at six tablets long term, talk it over with your practitioner. Bromelain comes from pineapple, so skip this one if pineapple doesn't agree with you.\u003c\/p\u003e\n\u003cp\u003eThe label carries this warning: \"WARNING: This product can expose you to chemicals including Lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.\"\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\/natural-allergy-solution-quercetin\"\u003eSee the certificates of analysis for this product\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility there puts formulators, makers and testers under one roof. The owners work in the building too, and have since 2017. Ingredients come from around the world; the making and the testing happen here. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much quercetin is in Quercetin Nettle+?\u003c\/h3\u003e\n\u003cp\u003eEach 3-tablet serving has 1,000 mg of quercetin, about 333 mg per tablet.\u003c\/p\u003e\n\u003ch3\u003eHow many tablets should I take, and how long does a bottle last?\u003c\/h3\u003e\n\u003cp\u003eThe label says three to six tablets daily. The 60-tablet bottle holds 20 servings of 3, so it's a 20-day supply at the label's 3-tablet serving and 10 days at six tablets a day.\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eThere's no set timeline, and you may not feel it day to day. That's normal: these nutrients work in the background of normal immune function and energy metabolism, so the goal is steady intake, not a buzz.†\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Quercetin Zinc, and how are they different?\u003c\/h3\u003e\n\u003cp\u003eYes, but add up the totals. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/quercetin-zinc\"\u003eQuercetin Zinc\u003c\/a\u003e is a 2-capsule serving with 530 mg of quercetin, 120 mg of vitamin C and 50 mg of bromelain, plus zinc, vitamin D3 and nettle root. One serving of each adds up to 1,530 mg of quercetin, 370 mg of vitamin C and 200 mg of bromelain. If you take both daily, run it by your practitioner.\u003c\/p\u003e\n\u003ch3\u003eIs Quercetin Nettle+ vegetarian?\u003c\/h3\u003e\n\u003cp\u003eYes. The label calls them vegetarian tablets and states: \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first. The safety review cited below found that quercetin can change how much of certain drugs reaches the bloodstream, so check before adding 1,000 mg or more a day.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/quercetin-zinc\"\u003eQuercetin Zinc with zinc, vitamin C and D3\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-c-buffered-vitamin-c\"\u003eGood C buffered vitamin C with bioflavonoids\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/quercetin-zinc-quercetin-nettle-hr\"\u003eBundle of Quercetin Zinc, Quercetin Nettle+ and YourHeart Nutrients\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eShanely RA et al. Quercetin supplementation does not alter antioxidant status in humans. Free Radical Research. 2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19947898\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAndres S et al. Safety Aspects of the Use of Quercetin as a Dietary Supplement. Molecular Nutrition \u0026amp; Food Research. 2018. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29127724\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCarr AC et al. Vitamin C and Immune Function. Nutrients. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29099763\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCastell JV et al. Intestinal absorption of undegraded proteins in men: presence of bromelain in plasma after oral intake. The American Journal of Physiology. 1997. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9252520\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDevkota HP et al. Stinging Nettle (\u003cem\u003eUrtica dioica\u003c\/em\u003e L.): Nutritional Composition, Bioactive Compounds, and Food Functional Properties. Molecules. 2022. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36014458\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424413466,"sku":"015-M1018","price":35.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1018_REV06_black_lid_necktag.png?v=1738588431"},{"product_id":"natural-sleep-aid-herbal-support","title":"Sleepy Sleep – Herbal Sleep Cycle Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eSleepy Sleep is a bedtime formula that pairs four traditional evening herbs with a little melatonin. Each capsule has 100 mg hops flower extract, 100 mg lemon balm leaf, 75 mg chamomile extract (1.2% apigenin), 50 mg passionflower extract, 25 mg 5-HTP, 20 mg magnesium and 1 mg melatonin. The bottle holds 60 vegetarian capsules. It helps you relax and supports a healthy sleep-wake cycle.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSleepy Sleep is for adults whose bodies are tired at bedtime but whose brains didn't get the memo. It spreads the work across a little melatonin, a serotonin building block and four bedtime herbs, not one big dose of anything.† If you're in your 30s or 40s and already working on how you'll feel at 70 and 80, a steady bedtime belongs on that list. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Sleepy Sleep\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTo relax and unwind at the end of the day, with chamomile, lemon balm, hops and passionflower in one capsule.†\u003c\/li\u003e\n\u003cli\u003eTo fall asleep more easily, with 1 mg of melatonin adding to the \"it's night\" signal the brain already sends.†\u003c\/li\u003e\n\u003cli\u003eTo support a healthy sleep-wake cycle when late screens or weekends push bedtime around.†\u003c\/li\u003e\n\u003cli\u003eTo supply 5-HTP, the building block the body uses to make serotonin, which it later turns into melatonin.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium (from magnesium citrate)\u003c\/td\u003e\n\u003ctd\u003e20 mg\u003c\/td\u003e\n\u003ctd\u003e4%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHops Flowers 4:1 Extract (Humulus lupulus)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLemon Balm Leaf (Melissa officinalis)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eChamomile Flower Standardized Extract (Matricaria recutita, standardized to 1.2% apigenin)\u003c\/td\u003e\n\u003ctd\u003e75 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePassionflower Herb 4:1 Extract (Passiflora incarnata)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e5-Hydroxytryptophan (5-HTP from Griffonia simplicifolia seed)\u003c\/td\u003e\n\u003ctd\u003e25 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMelatonin\u003c\/td\u003e\n\u003ctd\u003e1 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established. \u003cstrong\u003eServing size:\u003c\/strong\u003e 1 Vegetarian Capsule. \u003cstrong\u003eServings per container:\u003c\/strong\u003e 60 (the bottle holds 60 vegetarian capsules, and a serving is 1 capsule). \u003cstrong\u003eOther ingredients:\u003c\/strong\u003e Vegetable cellulose (from capsule shell) and marshmallow root. \u003cstrong\u003eLabel statement:\u003c\/strong\u003e \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow Sleepy Sleep works\u003c\/h2\u003e\n\u003ch3\u003eMelatonin: a small dose of the body's night signal\u003c\/h3\u003e\n\u003cp\u003eMelatonin is the hormone your brain releases in the evening as light fades. It doesn't knock you out; it tells your body it's night. Sleepy Sleep uses 1 mg, small on purpose. In a sleep-lab study, 12 healthy young volunteers took 0.3 mg, 1 mg or a placebo at 9 PM. Melatonin shortened the time it took to fall asleep, and neither dose changed the structure of their sleep or left them groggy the next morning (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e).† The study was small, tested melatonin alone, and dosed two to four hours before bedtime, not 45 to 60 minutes.\u003c\/p\u003e\n\u003ch3\u003e5-HTP: the step between tryptophan and serotonin\u003c\/h3\u003e\n\u003cp\u003eYour body turns tryptophan, an amino acid in food, into 5-HTP, then serotonin, then melatonin. The first step, tryptophan to 5-HTP, is the rate-limiting one, and supplemental 5-HTP starts past it (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33375373\/\"\u003eMaffei 2020\u003c\/a\u003e).† This 5-HTP comes from Griffonia simplicifolia seeds. At 25 mg it plays a supporting role. We haven't found sleep trials of that amount in healthy adults, so we claim no sleep effect for it alone.\u003c\/p\u003e\n\u003ch3\u003eChamomile: standardized to apigenin\u003c\/h3\u003e\n\u003cp\u003eThis chamomile extract is standardized to 1.2% apigenin, one of its main flavonoids (about 0.9 mg per capsule), so each batch carries a set amount of that compound, not just a set weight of flower. In a single-blind trial, 60 adults aged 60 and over took 200 mg of chamomile extract or a 200 mg wheat flour capsule twice a day for 28 days, and sleep quality scores came out better with chamomile (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29154054\/\"\u003eAdib-Hajbaghery 2017\u003c\/a\u003e).† That was 400 mg a day, far more than one capsule's 75 mg, in older adults who started out sleeping poorly.\u003c\/p\u003e\n\u003ch3\u003eLemon balm: the calm-down leaf\u003c\/h3\u003e\n\u003cp\u003eSleepy Sleep uses 100 mg of lemon balm leaf, a lemon-scented mint-family herb. In a double-blind crossover study, 18 healthy volunteers took a single 300 mg or 600 mg dose of a standardized extract, or a placebo, before a 20-minute multitasking stress test. After 600 mg they rated themselves calmer, and less alert, than after placebo (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15272110\/\"\u003eKennedy 2004\u003c\/a\u003e).† That was a daytime test of a larger dose, not a sleep study.\u003c\/p\u003e\n\u003ch3\u003eHops and passionflower: two traditional evening herbs\u003c\/h3\u003e\n\u003cp\u003eBoth are 4:1 extracts: about four parts of dried plant went into each part of extract. In a small study, 17 healthy female nurses working rotating or night shifts drank a non-alcoholic beer with hops at supper for 14 days; wrist monitors showed them falling asleep in about 12 minutes versus about 20.5 minutes in their own comparison period (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22815680\/\"\u003eFranco 2012\u003c\/a\u003e).† The researchers credit hops' bitter resins, which they say raise GABA, the brain's main calming messenger. No placebo, and it was beer, not a capsule.\u003c\/p\u003e\n\u003cp\u003ePassionflower is a climbing vine long used in the evening. In a double-blind trial, 41 healthy adults aged 18 to 35 drank passionflower tea or a placebo tea daily for a week each. Only one of six sleep-diary measures, sleep quality, came out better on passionflower (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21294203\/\"\u003eNgan 2011\u003c\/a\u003e).†\u003c\/p\u003e\n\u003ch3\u003eMagnesium: a small supporting amount\u003c\/h3\u003e\n\u003cp\u003eEach capsule has 20 mg of magnesium from magnesium citrate. Small studies find citrate is absorbed more completely than oxide, and adults need 310 to 420 mg a day (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Magnesium-HealthProfessional\/\"\u003eNIH Office of Dietary Supplements\u003c\/a\u003e), so this is a top-up. For more, see our \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/best-magnesium-supplements-for-sleep-2026\"\u003eguide to the magnesium amounts and forms used in sleep studies\u003c\/a\u003e, or \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium\u003c\/a\u003e, with 200 mg per capsule.\u003c\/p\u003e\n\u003ch3\u003eWhat the research does and doesn't show\u003c\/h3\u003e\n\u003cp\u003eNo trial has tested Sleepy Sleep as a formula. Each study above tested one ingredient, often at a different dose, form or time. The firmest evidence is for low-dose melatonin and falling asleep a bit faster; the herb studies are small, short, and often used more than one capsule provides.\u003c\/p\u003e\n\u003ch2\u003eHow to take Sleepy Sleep\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDirections (from the label):\u003c\/strong\u003e \"As a dietary supplement, one to two capsules 45 to 60 minutes prior to retiring for sleep.\"\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStart with one.\u003c\/strong\u003e One capsule is 1 mg of melatonin and 25 mg of 5-HTP. Two double everything, so move to two only if one isn't enough.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarning (from the label):\u003c\/strong\u003e \"Do not take prior to driving or operating heavy equipment. Not recommended while pregnant or lactating unless directed by health care practitioner. Individuals under 18 years old consult with health care practitioner before use.\" Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test. We test every incoming lot, the herbs included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Sleepy Sleep gets one.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 in the Willamette Valley, and our UL-certified cGMP facility is there. The people who formulate, make and test Sleepy Sleep work under one roof, and the owners work in the building too; the company has been owner-run since 2017. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow and when should I take Sleepy Sleep?\u003c\/h3\u003e\n\u003cp\u003eOne or two capsules, 45 to 60 minutes before sleep, per the label; it doesn't mention food either way. Start with one.\u003c\/p\u003e\n\u003ch3\u003eHow soon will I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eThe melatonin may help the first night: in the sleep-lab study, one evening dose shortened the time to fall asleep that same night (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e). The herb sleep studies ran one to four weeks, so give the formula a couple of weeks. Expect an easier wind-down, not a light switch.†\u003c\/p\u003e\n\u003ch3\u003eWill Sleepy Sleep make me groggy the next morning?\u003c\/h3\u003e\n\u003cp\u003eIt didn't happen with low-dose melatonin in the study we cite: in that 1996 study, neither 0.3 mg nor 1 mg left people worse off on next-morning mood or performance tests (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003eZhdanova 1996\u003c\/a\u003e). The full formula hasn't been tested for this, so try it first on a night you can sleep in.\u003c\/p\u003e\n\u003ch3\u003eCan I take Sleepy Sleep with Sleep Dots, Melatonin 3 mg or 5-HTP?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, because they overlap. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/sleep-dots-melatonin-1mg\"\u003eSleep Dots\u003c\/a\u003e have 1 mg of melatonin per dot, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/melatonin-3mg-timed-release\"\u003eMelatonin 3 mg Timed Release\u003c\/a\u003e has 3 mg per capsule, and our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/5-htp\"\u003e5-HTP\u003c\/a\u003e capsule has 100 mg of 5-HTP. None of these labels gives directions for combining them.\u003c\/p\u003e\n\u003ch3\u003eIs Sleepy Sleep safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner before you start. Melatonin and 5-HTP both sit on the body's serotonin-to-melatonin pathway (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33375373\/\"\u003eMaffei 2020\u003c\/a\u003e), so this matters most if you take anything that affects serotonin or a prescription sleep medicine.\u003c\/p\u003e\n\u003ch3\u003eIs Sleepy Sleep vegetarian?\u003c\/h3\u003e\n\u003cp\u003eThe label calls them vegetarian capsules. The shell is vegetable cellulose, and the only other item on the Other Ingredients list is marshmallow root.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calm-sleep-stack-sleepy-passion-ht\"\u003eCalm + Sleep Stack\u003c\/a\u003e: Sleepy Sleep, Relaxing Passion Flower and 5-HTP in one bundle.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/relaxation-supplement-passion-fl\"\u003eRelaxing Passion Flower\u003c\/a\u003e: 50 mg of passion flower 4:1 extract per lozenge, for use throughout the day.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eZhdanova IV et al. Effects of low oral doses of melatonin, given 2-4 hours before habitual bedtime, on sleep in normal young humans. Sleep. 1996. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8843534\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eMaffei ME. 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology. Int J Mol Sci. 2020. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33375373\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAdib-Hajbaghery M, Mousavi SN. The effects of chamomile extract on sleep quality among elderly people: A clinical trial. Complement Ther Med. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29154054\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKennedy DO et al. Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm). Psychosom Med. 2004. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15272110\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eFranco L et al. The sedative effect of non-alcoholic beer in healthy female nurses. PLoS One. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22815680\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eNgan A, Conduit R. A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality. Phytother Res. 2011. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21294203\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424380698,"sku":"015-M1021","price":25.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1021_REV02_Necktag.png?v=1738590271"},{"product_id":"relaxation-supplement-passion-fl","title":"Relaxing Passion Flower 50 mg – Promotes Relaxation | 60 Vegetarian Lozenges","description":"\u003cp\u003e\u003cstrong\u003eRelaxing Passion Flower is a single-ingredient herbal lozenge. Each vegetarian lozenge delivers 50 mg of Passion Flower 4:1 Extract (Passiflora incarnata), and each bottle holds 60. You let it dissolve in your mouth; the label says one or more lozenges throughout the day. Passionflower is traditionally used to promote relaxation, so you can take the edge off a busy day and wind down at night.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis is for the person whose day doesn't come with an off switch: work, kids, parents, a phone that never stops buzzing. You want something small you can keep in a bag or a desk drawer, take without water, and reach for when the day gets loud.\u003c\/p\u003e\n\u003cp\u003eAging isn't optional. Getting old is. A wind-down routine you start in your 30s and 40s is one you can still be using in your 70s, so build one you'll actually keep. A lozenge, a few slow breaths and the phone in another room is a decent start.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Relaxing Passion Flower\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTo promote relaxation, the one job printed on the label.†\u003c\/li\u003e\n\u003cli\u003eTo take the edge off occasional, everyday stress.†\u003c\/li\u003e\n\u003cli\u003eTo support a calm, settled mood through a packed day.†\u003c\/li\u003e\n\u003cli\u003eTo help them wind down in the evening and support restful sleep.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePassion Flower 4:1 Extract (Passiflora incarnata)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003e* (Daily Value Not Established)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 1 Vegetarian Lozenge. With 60 lozenges in the bottle and a one-lozenge serving, that's 60 servings. Other ingredients: Xylitol, organic evaporated cane juice, cellulose, palm kernel stearate, citric acid, natural flavor, and silica. The label states: \"NO alcohol, soy, salt, yeast, gluten, milk \u0026amp; egg products, starch, or preservatives.\" It also states: \"One lozenge is 2 times the strength of one dropperful (35 drops) of liquid passion flower alcohol extract.\"\u003c\/p\u003e\n\u003ch2\u003eHow Relaxing Passion Flower works\u003c\/h2\u003e\n\u003ch3\u003ePassionflower, the plant\u003c\/h3\u003e\n\u003cp\u003ePassiflora incarnata is a climbing vine. People have used it for a long time, and in North America it has a history as a calming tea (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24140586\/\"\u003ea 2013 review of passionflower's traditional use and clinical research\u003c\/a\u003e). Relaxing Passion Flower keeps it simple: one herb, one amount, nothing else doing the work.\u003c\/p\u003e\n\u003ch3\u003eWhat \"4:1 extract\" means\u003c\/h3\u003e\n\u003cp\u003eA 4:1 extract means roughly 4 parts of starting plant material go into every 1 part of finished extract. So the 50 mg in each lozenge is a concentrate, not 50 mg of ground-up plant. The label identifies the extract by that ratio. It doesn't claim standardization to a specific marker compound, so we won't either.\u003c\/p\u003e\n\u003ch3\u003eThe GABA connection\u003c\/h3\u003e\n\u003cp\u003eYour nervous system runs on a balance of \"go\" and \"ease off\" signals. GABA (gamma-aminobutyric acid) is the main \"ease off\" messenger. In a lab study using rat brain tissue, a passionflower dry extract showed affinity for both main types of GABA receptors (GABA-A and GABA-B) and reduced GABA uptake into nerve endings, and the authors concluded that passionflower acts partly through the GABA system (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21089181\/\"\u003ea lab study of passionflower and the GABA system\u003c\/a\u003e). That's test-tube work, and the picture isn't one-directional (the extract blocked GABA-B receptors in one test). It suggests a way passionflower may help you relax, but it can't tell us what one lozenge does inside a person.†\u003c\/p\u003e\n\u003ch3\u003eWhat the human research shows, and what it doesn't\u003c\/h3\u003e\n\u003cp\u003eThe clearest study in healthy people is small. In a double-blind, placebo-controlled crossover trial, 41 healthy adults aged 18 to 35 drank a cup of passionflower tea or a placebo tea daily for a week each and kept a sleep diary. Of six sleep-diary measures, sleep quality was the one rated significantly higher with passionflower (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21294203\/\"\u003ea crossover study of passionflower tea in 41 healthy adults\u003c\/a\u003e).† The authors called the benefit short-term and subjective, in healthy adults with mild ups and downs in sleep quality. Encouraging, not conclusive: it was tea, not a lozenge, and it lasted one week.\u003c\/p\u003e\n\u003cp\u003eThe 2013 review above found that many passionflower trials were small, described their extracts poorly, or skipped details on blinding and randomization, and its authors called for better-designed studies. The same review described the plant's safety profile as good. We'd rather tell you that up front than oversell a 50 mg lozenge.\u003c\/p\u003e\n\u003ch3\u003eWhy a lozenge\u003c\/h3\u003e\n\u003cp\u003eA lozenge dissolves slowly in your mouth. No water, no capsule to swallow, and no alcohol in the lozenge itself. We haven't seen research showing a lozenge absorbs differently than a capsule, so the lozenge is about convenience, not absorption.\u003c\/p\u003e\n\u003cp\u003eThe rest of the lozenge is there to make it a lozenge. Xylitol and organic evaporated cane juice sweeten it. Cellulose binds it, palm kernel stearate and silica keep the blend from sticking and clumping during production, and citric acid and natural flavor handle the taste. Organic evaporated cane juice is a form of cane sugar, so this lozenge isn't sugar-free.\u003c\/p\u003e\n\u003ch3\u003eWhy we test the extract itself\u003c\/h3\u003e\n\u003cp\u003eHerbal extracts are easy to get wrong. When German researchers analyzed a set of passionflower products, five of the six food supplements they tested failed identity or content checks, while all five registered herbal medicinal products passed. Their advice to manufacturers: test every batch (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40245939\/\"\u003ea 2025 quality analysis of passionflower products\u003c\/a\u003e). That's a small sample, not a verdict on any particular company. It is exactly why we test every incoming ingredient lot before it's used.\u003c\/p\u003e\n\u003ch2\u003eHow to take Relaxing Passion Flower\u003c\/h2\u003e\n\u003cp\u003eThe label directions: \"Take one or more lozenges throughout the day, as a dietary supplement.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLet the lozenge dissolve slowly in your mouth instead of chewing it or swallowing it whole.\u003c\/li\u003e\n\u003cli\u003eStart with one and see how you feel. The label doesn't set a daily maximum, so if you find yourself wanting several a day, check in with your practitioner.\u003c\/li\u003e\n\u003cli\u003ePassionflower is taken to help you relax, so see how it affects you before you drive or do anything that needs your full attention.\u003c\/li\u003e\n\u003cli\u003eEach lozenge contains xylitol, which is dangerous for dogs. Keep the bottle where pets can't get to it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, passionflower extract included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Relaxing Passion Flower gets its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e That's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility is where the formulators, the makers and the testers all work under one roof. The owners work in the building too, and the company has been owner-run since 2017. We've been making supplements in Oregon since 1974. And we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many Relaxing Passion Flower lozenges can I take a day?\u003c\/h3\u003e\n\u003cp\u003eThe label says to take one or more lozenges throughout the day, and it doesn't set a daily maximum. Start with one, see how you feel, and talk with your practitioner if you find you want several a day.\u003c\/p\u003e\n\u003ch3\u003eWhen should I take it, and do I need food or water?\u003c\/h3\u003e\n\u003cp\u003eTake it whenever you want to wind down. The label doesn't mention food, and because it dissolves in your mouth, you don't need water. The label says throughout the day, so that can be a midafternoon lozenge before a tough meeting or one after dinner as your evening slows down.†\u003c\/p\u003e\n\u003ch3\u003eHow long does it take to notice anything?\u003c\/h3\u003e\n\u003cp\u003eWe can't give you a number; there's no timing data on this lozenge. In the small tea study above, people drank the tea daily for a week before their sleep ratings were compared, and that's the only timeline the research gives us.†\u003c\/p\u003e\n\u003ch3\u003eIs Relaxing Passion Flower sugar-free?\u003c\/h3\u003e\n\u003cp\u003eNo. It's sweetened with xylitol and organic evaporated cane juice, which is a form of cane sugar.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Sleepy Sleep?\u003c\/h3\u003e\n\u003cp\u003eYes, and we sell them together in the \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calm-sleep-stack-sleepy-passion-ht\"\u003eCalm + Sleep Stack with Sleepy Sleep, Relaxing Passion Flower and 5-HTP\u003c\/a\u003e. Know that Sleepy Sleep also contains 50 mg of Passionflower Herb 4:1 Extract per capsule, plus melatonin and 5-HTP. Its label calls for one to two capsules 45 to 60 minutes before sleep, warns against taking it before driving, says it isn't recommended while pregnant or nursing unless a practitioner directs it, and asks anyone under 18 to check with a practitioner first. A simple split: a lozenge during the day when you want one, Sleepy Sleep at bedtime.\u003c\/p\u003e\n\u003ch3\u003eHow is a lozenge different from passionflower capsules or tinctures?\u003c\/h3\u003e\n\u003cp\u003eMostly it's convenience: it dissolves in your mouth, needs no water and contains no alcohol. The label says one lozenge is 2 times the strength of one dropperful (35 drops) of liquid passion flower alcohol extract. We don't claim it absorbs differently than a capsule.\u003c\/p\u003e\n\u003ch3\u003eIs it safe with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first. Passionflower is taken to help you relax, so it could add to the effects of other things that make you drowsy, including some prescriptions and alcohol. Check with them too if you're pregnant or nursing.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/natural-sleep-aid-herbal-support\"\u003eSleepy Sleep, our bedtime formula with chamomile, hops, passionflower and 1 mg melatonin per capsule\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calm-sleep-stack-sleepy-passion-ht\"\u003eThe Calm + Sleep Stack, all three bottles in one order\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/calming-magnesium-powder-relax\"\u003eCalming Mag Powder, a magnesium drink for your bedtime routine\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eMiroddi M et al. Passiflora incarnata L.: ethnopharmacology, clinical application, safety and evaluation of clinical trials. J Ethnopharmacol. 2013. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24140586\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAppel K et al. Modulation of the γ-aminobutyric acid (GABA) system by Passiflora incarnata L. Phytother Res. 2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21089181\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eNgan A et al. A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality. Phytother Res. 2011. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21294203\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBrouns A et al. Passionflower (Passiflora incarnata): Quality of Food Supplements Versus Registered Herbal Medicinal Products. Planta Med. 2025. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40245939\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424347930,"sku":"015-M1024","price":21.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1024_REV03_Necktag.png?v=1738590323"},{"product_id":"bones-k2-comprehensive-bone-supp","title":"Bones + K2 with Aquamin Calcium – Healthy Bone Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eBones + K2 is a daily bone-support formula in 60 vegetarian capsules, a 30-day supply. Each two-capsule serving gives you 500 mg of calcium and 40 mg of magnesium from Aquamin™ red algae minerals, plus 25 mcg of vitamin D3, 120 mcg of vitamin K2 as MK-7, 2 mg of manganese and 3 mg of boron, nutrients that work together to support healthy bones.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eYour skeleton is not a finished product. Bone is living tissue your body constantly breaks down and rebuilds, and that takes a steady supply of calcium, vitamin D and a few lesser-known helpers. Bones + K2 puts them in one bottle, with calcium from red seaweed. It's for people in their 30s and 40s building habits for the decades ahead, and for people past 50 who plan to stay strong and hard to keep up with. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Bones + K2\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCalcium is the main mineral in bone, and each serving supplies 500 mg of it, plus 40 mg of magnesium, to support bone structure.†\u003c\/li\u003e\n\u003cli\u003eVitamin D3 helps your gut absorb calcium and supports normal bone mineralization.†\u003c\/li\u003e\n\u003cli\u003eVitamin K2 (MK-7) helps activate osteocalcin, a bone protein that binds calcium, to support healthy bone.†\u003c\/li\u003e\n\u003cli\u003eManganese supports normal bone formation, and boron may support calcium and vitamin D metabolism.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin D (Cholecalciferol)\u003c\/td\u003e\n\u003ctd\u003e25 mcg\u003c\/td\u003e\n\u003ctd\u003e125%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin K (K2, Menaquinone MK7)\u003c\/td\u003e\n\u003ctd\u003e120 mcg\u003c\/td\u003e\n\u003ctd\u003e100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCalcium (Calcium Carbonate, from Aquamin™ Marine Minerals)\u003c\/td\u003e\n\u003ctd\u003e500 mg\u003c\/td\u003e\n\u003ctd\u003e38%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium (Magnesium Carbonate, from Aquamin™ Marine Minerals)\u003c\/td\u003e\n\u003ctd\u003e40 mg\u003c\/td\u003e\n\u003ctd\u003e9%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eManganese (Manganese Citrate)\u003c\/td\u003e\n\u003ctd\u003e2 mg\u003c\/td\u003e\n\u003ctd\u003e86%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBoron (Boron Citrate)\u003c\/td\u003e\n\u003ctd\u003e3 mg\u003c\/td\u003e\n\u003ctd\u003e* Daily Value not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 2 vegetarian capsules. Servings per container: 30. Other ingredients: Vegetable Cellulose (from capsule shell), Organic Rice Extract, Organic Rice Concentrate, and Cellulose. The label states: \"NO corn, soy, salt, yeast, wheat, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" It also notes that Aquamin™ Sea Minerals are \"a unique form of calcium from red algae (seaweed), \u003cem\u003eLithothamnion\u003c\/em\u003e species.\"\u003c\/p\u003e\n\u003ch2\u003eHow Bones + K2 works\u003c\/h2\u003e\n\u003ch3\u003eAquamin™: calcium and magnesium from red seaweed\u003c\/h3\u003e\n\u003cp\u003eAquamin comes from \u003cem\u003eLithothamnion\u003c\/em\u003e, a red seaweed that builds a hard, chalky structure out of minerals it pulls from seawater. The label lists calcium carbonate and magnesium carbonate because chemically, that's what they are. What's different is the source: a vegetarian calcium that brings magnesium along. Calcium carbonate absorbs best with a meal, and the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Calcium-HealthProfessional\/\"\u003eNIH calcium fact sheet\u003c\/a\u003e notes that absorption from supplements is highest at 500 mg or less at a time. One serving is exactly 500 mg.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24453130\/\"\u003ea two-year trial in 300 postmenopausal women\u003c\/a\u003e, 800 mg a day of calcium from a marine-derived multi-mineral made no difference to bone mineral density compared with placebo, but markers of bone turnover (how fast old bone is broken down and replaced) fell more by 12 months, which the researchers read as a more favorable bone profile. A modest result, from more calcium than one serving here.\u003c\/p\u003e\n\u003cp\u003eAbout 50% to 60% of your body's magnesium sits in bone, per the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Magnesium-HealthProfessional\/\"\u003eNIH magnesium fact sheet\u003c\/a\u003e. At 40 mg (9% DV), it plays a supporting role here. For more, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium adds 200 mg per capsule\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eVitamin D3: helps you absorb the calcium\u003c\/h3\u003e\n\u003cp\u003eVitamin D helps your gut absorb calcium and keeps blood calcium and phosphate where they need to be for normal bone mineralization.† This formula uses D3 (cholecalciferol), and the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminD-HealthProfessional\/\"\u003eNIH vitamin D fact sheet\u003c\/a\u003e says most evidence shows D3 raises blood vitamin D levels further, and keeps them up longer, than D2. The 25 mcg here equals 1,000 IU, a quarter of the adult upper limit.\u003c\/p\u003e\n\u003ch3\u003eVitamin K2 as MK-7: puts calcium-binding protein to work\u003c\/h3\u003e\n\u003cp\u003eHere's the part most people skip. Bone makes a protein called osteocalcin that binds calcium, and it only works after vitamin K switches it on through a chemical step called carboxylation, as the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminK-HealthProfessional\/\"\u003eNIH vitamin K fact sheet\u003c\/a\u003e explains.†\u003c\/p\u003e\n\u003cp\u003eWhy MK-7? It's the longer-lasting form of K2. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23140417\/\"\u003ea study comparing MK-4 and MK-7 in healthy women\u003c\/a\u003e, a single MK-7 dose peaked in blood at about 6 hours and was still detectable at 48, while the same dose of MK-4 never showed up in blood. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22289649\/\"\u003ea dose-finding trial in 42 healthy adults aged 18 to 45\u003c\/a\u003e, MK-7 at doses around the recommended daily intake increased the share of osteocalcin in its active form.\u003c\/p\u003e\n\u003cp\u003eWhat about bone density? The evidence is mixed. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23525894\/\"\u003ea three-year trial in 244 healthy postmenopausal women\u003c\/a\u003e, 180 mcg a day of MK-7 improved vitamin K status, and that group lost less bone mineral density with age at the lower spine and femoral neck (not the total hip) than the placebo group. A \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19937427\/\"\u003eone-year trial in 334 healthy women in early menopause\u003c\/a\u003e using 360 mcg a day activated more osteocalcin but found no difference in bone density loss. MK-7 did its biochemical job in both; whether that shows up on a bone scan may depend on study length and who's taking part. This formula has 120 mcg (100% DV), less than either trial used.\u003c\/p\u003e\n\u003ch3\u003eManganese and boron: the supporting cast\u003c\/h3\u003e\n\u003cp\u003eManganese helps enzymes involved in bone formation, and 25% to 40% of your body's manganese is stored in bone, per the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Manganese-HealthProfessional\/\"\u003eNIH manganese fact sheet\u003c\/a\u003e.† The 2 mg here is well under the 11 mg adult upper limit. Boron, candidly, isn't even classified as an essential nutrient, but the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Boron-HealthProfessional\/\"\u003eNIH boron fact sheet\u003c\/a\u003e says it might play a role in calcium metabolism, bone formation and vitamin D use. The 3 mg here is well under the 20 mg adult upper limit.\u003c\/p\u003e\n\u003ch2\u003eHow to take Bones + K2\u003c\/h2\u003e\n\u003cp\u003eThe label says: \"Two capsules daily, as a dietary supplement.\" Take them with a meal: calcium carbonate absorbs best with food, and vitamins D and K are fat-soluble, so a meal with some fat helps.\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. That goes double if you take a blood thinner such as warfarin, because vitamin K affects how it works.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, the Aquamin included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Bones + K2 has one, documenting what our testing found.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e That's a farm town of about 3,500 people in the Willamette Valley. Our formulators, makers and testers work under one roof in a UL-certified cGMP facility, and the owners work in the building too. We've been making supplements in Oregon since 1974. That's 52 years of making supplements, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow do I take Bones + K2?\u003c\/h3\u003e\n\u003cp\u003eTake two capsules a day, as the label directs, ideally with a meal that has some fat in it. One bottle is a 30-day supply.\u003c\/p\u003e\n\u003ch3\u003eIs 500 mg of calcium enough?\u003c\/h3\u003e\n\u003cp\u003eIt isn't meant to be your whole day. 500 mg is 38% of the Daily Value, and adults need 1,000 to 1,200 mg a day from food and supplements combined, so your plate covers the rest.\u003c\/p\u003e\n\u003ch3\u003eHow long before I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eProbably never in a way you can feel, and that's normal. Bone renews slowly, and the bone density trials above ran one to three years and measured bone scans and blood markers, not how people felt. Think of it like brushing your teeth.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with a Mt. Angel multivitamin?\u003c\/h3\u003e\n\u003cp\u003eYes. The \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-50-plus-multivitamin\"\u003eWomen's 50+ Multivitamin\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-50-plus-multivitamin\"\u003eMen's 50+ Multivitamin\u003c\/a\u003e each add 25 mcg of vitamin D3, 80 mcg of K2 and 2 mg of manganese. Combined with Bones + K2, that's 50 mcg (2,000 IU) of vitamin D and 4 mg of manganese a day, under the adult upper limits of 100 mcg and 11 mg. Vitamin K has no set upper limit.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Everyday Liquid Sunshine 2 or Bone Power Strontium?\u003c\/h3\u003e\n\u003cp\u003eNot casually. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/everyday-liquid-sunshine-2-d3-k2\"\u003eEveryday Liquid Sunshine 2\u003c\/a\u003e has 125 mcg (5,000 IU) of vitamin D3 per serving, so together you'd get 150 mcg (6,000 IU) a day, above the 100 mcg adult upper limit. Combine them only on your practitioner's advice. The \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/bone-power-strontium\"\u003eBone Power Strontium\u003c\/a\u003e label says to take it 2 hours before or after calcium products, so keep them 2 hours apart.\u003c\/p\u003e\n\u003ch3\u003eHow is Bones + K2 different from Nice Bones?\u003c\/h3\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/nice-bones\"\u003eNice Bones\u003c\/a\u003e gives more calcium and magnesium (1,200 mg and 600 mg) plus 25 mcg of vitamin D2 in three tablets, with no vitamin K. Bones + K2 uses seaweed calcium and vitamin D3, and adds vitamin K2, manganese and boron.\u003c\/p\u003e\n\u003ch3\u003eIs Bones + K2 safe with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, especially if you take a blood thinner such as warfarin, since the NIH advises keeping vitamin K intake consistent on those drugs. Calcium carbonate can also reduce absorption of some medications, such as levothyroxine, so ask about spacing them apart.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/single-bottle-solution-what-is-it-and-why-do-we-put-it-on-our-premium-bottles\"\u003eWhat \"Single Bottle Solution\" on the side of the bottle means\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/our-approach-to-raw-material-sourcing-and-testing\"\u003eHow we source and test raw materials\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eSlevin MM et al. Supplementation with calcium and short-chain fructo-oligosaccharides affects markers of bone turnover but not bone mineral density in postmenopausal women. J Nutr. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24453130\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSato T et al. Comparison of menaquinone-4 and menaquinone-7 bioavailability in healthy women. Nutr J. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23140417\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eTheuwissen E et al. Low-dose menaquinone-7 supplementation improved extra-hepatic vitamin K status, but had no effect on thrombin generation in healthy subjects. Br J Nutr. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22289649\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKnapen MH et al. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporos Int. 2013. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23525894\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eEmaus N et al. Vitamin K2 supplementation does not influence bone loss in early menopausal women: a randomised double-blind placebo-controlled trial. Osteoporos Int. 2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19937427\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424282394,"sku":"015-M5010","price":27.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M5010_REV03_Necktag.png?v=1744037575"},{"product_id":"eye-complete-vitamin-macular-blue","title":"Eye Complete – Lutein \u0026 Zeaxanthin Vision Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eEye Complete is a daily eye formula with 20 mg of lutein and 4 mg of zeaxanthin from Lutemax® 2020 marigold extract in every 2-capsule serving, plus vitamins A, C and E, 25 mg of zinc, copper, 100 mg of bilberry extract and an NAC and glutathione blend. A bottle holds 60 vegetarian capsules (30 servings). It helps build macular pigment, which filters blue light, and supports healthy vision.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLaptop, phone, TV, repeat: your eyes put in long hours in front of screens. Eye Complete is built for people in their late 30s and 40s who want their eyes to keep up for decades, and for anyone over 50 who plans to keep reading, driving and people-watching for a long time. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Eye Complete\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMacular pigment support.\u003c\/strong\u003e Lutein and zeaxanthin are the yellow pigments concentrated in your macula, the center of the retina that handles sharp, detailed vision.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHelps protect eyes from blue light.\u003c\/strong\u003e Macular pigment absorbs blue light before it reaches the light-sensing cells behind it.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVisual performance and screen-day comfort.\u003c\/strong\u003e In a trial in heavy screen users, 24 mg a day of macular carotenoids improved contrast and glare measures and self-reported eye strain compared with placebo.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntioxidant support.\u003c\/strong\u003e Vitamins C and E, zinc and copper support your body's normal defenses against everyday oxidative stress.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNormal vision in dim light.\u003c\/strong\u003e Vitamin A is part of rhodopsin, the light-sensing protein your retina relies on in low light.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin A (palmitate)\u003c\/td\u003e\n\u003ctd\u003e900 mcg RAE\u003c\/td\u003e\n\u003ctd\u003e100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin C (ascorbic acid)\u003c\/td\u003e\n\u003ctd\u003e500 mg\u003c\/td\u003e\n\u003ctd\u003e555%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin E (d-alpha tocopherol)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003e100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eZinc (chelate)\u003c\/td\u003e\n\u003ctd\u003e25 mg\u003c\/td\u003e\n\u003ctd\u003e227%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCopper (chelate)\u003c\/td\u003e\n\u003ctd\u003e1 mg\u003c\/td\u003e\n\u003ctd\u003e111%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBilberry Fruit Extract (from Vaccinium myrtillus, standardized to 25% anthocyanosides)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLutein (From Lutemax® 2020 marigold flower extract)\u003c\/td\u003e\n\u003ctd\u003e20 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eZeaxanthin (From Lutemax® 2020 marigold flower extract)\u003c\/td\u003e\n\u003ctd\u003e4 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eProprietary Blend (contains N-Acetyl Cysteine (NAC) and L-Glutathione)\u003c\/td\u003e\n\u003ctd\u003e75 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established. Serving size: 2 Vegetarian Capsules. Servings per container: 30 (60 vegetarian capsules). Other ingredients: Cellulose (from capsule shell), Organic Rice Concentrate, Organic Rice Extract. The label states: \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow Eye Complete works\u003c\/h2\u003e\n\u003ch3\u003eLutein and zeaxanthin (Lutemax® 2020), 20 mg and 4 mg\u003c\/h3\u003e\n\u003cp\u003eLutein and zeaxanthin are carotenoids, the pigment family that colors marigolds and egg yolks. In the macula they form macular pigment, which absorbs blue light and acts as an antioxidant in light-exposed tissue.† Here they come from Lutemax® 2020, a marigold flower extract.\u003c\/p\u003e\n\u003cp\u003eDo supplements raise macular pigment? \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34157098\/\"\u003eA systematic review of 46 studies in 3,189 adults with healthy eyes\u003c\/a\u003e (average age 43) found it rose by about 0.04 units on 5 to under 20 mg a day and about 0.11 units on 20 mg or more a day, over 3 to 12 months. The authors note that the amount needed for a meaningful change in vision isn't settled.\u003c\/p\u003e\n\u003cp\u003eDoes more pigment matter? \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32792595\/\"\u003eA review of macular pigment and visual function in healthy eyes\u003c\/a\u003e found that people with more of it tended to have better contrast sensitivity and less trouble with glare, a correlation rather than proof. For a direct test, \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28661438\/\"\u003ea 6-month placebo-controlled trial in 48 healthy young adults\u003c\/a\u003e who spent at least 6 hours a day on screens used 24 mg a day of lutein, zeaxanthin and meso-zeaxanthin, the same 24 mg total as a serving of Eye Complete. Compared with placebo, they gained macular pigment, scored better on contrast, glare and bright-light recovery tests, and reported less eye strain and eye fatigue. It was one small trial with self-reported symptoms: encouraging, not settled.\u003c\/p\u003e\n\u003ch3\u003eVitamin A (palmitate), 900 mcg RAE\u003c\/h3\u003e\n\u003cp\u003eVitamin A is part of rhodopsin, the retina's light-sensing protein for dim light, and it supports normal function of the cornea.† Retinyl palmitate is preformed vitamin A, so no conversion from beta-carotene is needed. The \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminA-HealthProfessional\/\"\u003eNIH vitamin A fact sheet\u003c\/a\u003e puts absorption of preformed vitamin A from supplements at 70% to 90%, compared with 8.7% to 65% for beta-carotene.\u003c\/p\u003e\n\u003ch3\u003eVitamins C and E, 500 mg and 15 mg\u003c\/h3\u003e\n\u003cp\u003eVitamin C works in watery parts of the body and vitamin E in fatty cell membranes, and both help defend cells against oxidative stress.† The vitamin E here is d-alpha tocopherol, the naturally sourced form. The \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminE-HealthProfessional\/\"\u003eNIH vitamin E fact sheet\u003c\/a\u003e explains that synthetic vitamin E (dl-alpha tocopherol) is a mix of eight versions of the molecule, and your blood and tissues keep only four of them.\u003c\/p\u003e\n\u003ch3\u003eZinc and copper (chelates), 25 mg and 1 mg\u003c\/h3\u003e\n\u003cp\u003eZinc is needed for the activity of hundreds of enzymes, and zinc and copper together are part of one of your body's main antioxidant enzymes.† Why both? Over time, a lot of zinc can crowd out copper. The \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Zinc-HealthProfessional\/\"\u003eNIH zinc fact sheet\u003c\/a\u003e notes that weeks of 50 mg or more of zinc a day can interfere with copper absorption, and it sets the adult upper limit at 40 mg a day from all sources, food included. The label lists both minerals as chelates, meaning each is bound to an organic molecule rather than supplied as an inorganic form such as zinc oxide.\u003c\/p\u003e\n\u003ch3\u003eBilberry fruit extract, 100 mg\u003c\/h3\u003e\n\u003cp\u003eBilberry, a European cousin of the blueberry, gets its color from anthocyanins (the label says anthocyanosides); at 25%, a serving carries about 25 mg. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32106548\/\"\u003eA 12-week placebo-controlled trial in 109 healthy adults aged 20 to 60\u003c\/a\u003e gave 240 mg a day of a standardized bilberry extract and measured tension in the eye's focusing muscle after screen and close-up work. At weeks 8 and 12, focusing-muscle readings were significantly improved in the bilberry group compared with placebo.† That dose was more than twice the extract in a serving here.\u003c\/p\u003e\n\u003cp\u003eWhat the evidence doesn't support: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14711439\/\"\u003ea systematic review of placebo-controlled bilberry trials\u003c\/a\u003e concluded that the better-designed randomized trials don't support the idea that it improves normal night vision. So it's here for its anthocyanins, not as a night-vision promise.\u003c\/p\u003e\n\u003ch3\u003eNAC and glutathione blend, 75 mg\u003c\/h3\u003e\n\u003cp\u003eGlutathione is an antioxidant your body makes on its own, and NAC (N-acetyl cysteine) supplies cysteine, one of its building blocks. The label doesn't disclose the split, and 75 mg is a small amount, so think of this blend as a supporting player, not the headline.\u003c\/p\u003e\n\u003ch3\u003eWhat the research does and doesn't show\u003c\/h3\u003e\n\u003cp\u003eWe know of no published trial of this exact formula. The lutein and zeaxanthin research is the strongest part; the bilberry evidence is thinner and used a bigger dose. None of it replaces regular eye exams.\u003c\/p\u003e\n\u003ch2\u003eHow to take Eye Complete\u003c\/h2\u003e\n\u003cp\u003eDirections from the label: Take two capsules per day, as a dietary supplement.\u003c\/p\u003e\n\u003cp\u003eThe label doesn't set a time of day. Lutein, zeaxanthin and vitamins A and E are fat-soluble, so a meal with some fat in it is a sensible time to take Eye Complete. If you take other supplements, add up your zinc and vitamin A. Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test. We test every incoming lot, marigold extract included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Each one records what that lot was tested for and what the results were.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility sits right in it. The people who formulate Eye Complete, make it and test it work under one roof, and the owners work in the building too (owner-run since 2017). We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much lutein and zeaxanthin is in Eye Complete?\u003c\/h3\u003e\n\u003cp\u003eEach 2-capsule serving has 20 mg of lutein and 4 mg of zeaxanthin from Lutemax® 2020 marigold flower extract, 24 mg in all.\u003c\/p\u003e\n\u003ch3\u003eHow long before I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eGive it months, not days. The studies above measured changes over 3 to 12 months, and macular pigment is something an eye professional measures, not something you feel.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with the Men's 50+ or Women's 50+ Multivitamin?\u003c\/h3\u003e\n\u003cp\u003eAsk your practitioner first, mainly because of zinc. The \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-50-plus-multivitamin\"\u003eMen's 50+ Multivitamin\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-50-plus-multivitamin\"\u003eWomen's 50+ Multivitamin\u003c\/a\u003e each have 15 mg of zinc per serving, so with Eye Complete you'd get 40 mg a day from supplements alone, the adult upper limit for all sources combined. Each multi also adds 750 mcg RAE of vitamin A, 10 mg of lutein and 2 mg of zeaxanthin.\u003c\/p\u003e\n\u003ch3\u003eIs Eye Complete vegetarian, and what is it free of?\u003c\/h3\u003e\n\u003cp\u003eThe label calls them vegetarian capsules, and the shell is cellulose. The label also states: \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner before you start, and bring the bottle so they can read the full label.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/single-bottle-solution-what-is-it-and-why-do-we-put-it-on-our-premium-bottles\"\u003eWhat \"Single Bottle Solution\" on the Eye Complete label means\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003eDaily multis with Lutemax® 2020 lutein: \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-50-plus-multivitamin\"\u003eMen's 50+ Multivitamin\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-50-plus-multivitamin\"\u003eWomen's 50+ Multivitamin\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eWilson LM et al. The Effect of Lutein\/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis. Adv Nutr. 2021. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34157098\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eJohnson EJ et al. The association between macular pigment optical density and visual function outcomes: a systematic review and meta-analysis. Eye (Lond). 2021. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32792595\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eStringham JM et al. Macular Carotenoid Supplementation Improves Visual Performance, Sleep Quality, and Adverse Physical Symptoms in Those with High Screen Time Exposure. Foods. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28661438\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKosehira M et al. A 12-Week-Long Intake of Bilberry Extract (Vaccinium myrtillus L.) Improved Objective Findings of Ciliary Muscle Contraction of the Eye: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Trial. Nutrients. 2020. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32106548\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCanter PH et al. Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision--a systematic review of placebo-controlled trials. Surv Ophthalmol. 2004. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14711439\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424216858,"sku":"015-M1006","price":41.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1006_REV04_Listing_Image_1_54ae3a61-8295-4731-bb22-f2114fa6afd3.png?v=1738258263"},{"product_id":"nutrisilk-hair-skin-nail-support","title":"NutriSilk – Hair, Skin \u0026 Nail Support With Biotin \u0026 Collagen | 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eNutriSilk is a hair, skin and nail supplement in capsule form. Each 2-capsule serving provides 5,000 mcg of biotin, 15 mg of zinc (citrate), 1 mg of copper, 35 mcg of selenium, four B vitamins including 250 mg of niacinamide, and a 750 mg blend of gelatin, hyaluronic acid and chicken collagen. One 60-capsule bottle is a 30-day supply. NutriSilk supports strong hair and nails and healthy skin.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNutriSilk is for people who want their hair, skin and nails to keep pace with the rest of their routine. Collagen gives skin its structure, hyaluronic acid helps it hold water, and hair and nails are made of keratin, a protein your body builds from what you eat. It's an easy habit to start in your 30s and 40s, rather than something to save for later. Below is every amount on the label, what each ingredient does, and an honest read on where the research is strong and where it's thin.\u003c\/p\u003e\n\u003ch2\u003eWhy people take NutriSilk\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTo support strong hair and nails and healthy skin, with 5,000 mcg of biotin in every serving.†\u003c\/li\u003e\n\u003cli\u003eFor zinc and copper, two minerals the body uses to build proteins and connective tissue.†\u003c\/li\u003e\n\u003cli\u003eFor collagen and hyaluronic acid, two things your skin is made of, together in one 750 mg blend.†\u003c\/li\u003e\n\u003cli\u003eFor four B vitamins (riboflavin, niacinamide, B6 and pantothenic acid) that help turn food into energy.†\u003c\/li\u003e\n\u003cli\u003eFor selenium, which your body builds into its own antioxidant enzymes.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eRiboflavin\u003c\/td\u003e\n\u003ctd\u003e10 mg\u003c\/td\u003e\n\u003ctd\u003e769%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNiacinamide\u003c\/td\u003e\n\u003ctd\u003e250 mg NE\u003c\/td\u003e\n\u003ctd\u003e1,562%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B6 (from pyridoxine HCl)\u003c\/td\u003e\n\u003ctd\u003e20 mg\u003c\/td\u003e\n\u003ctd\u003e1,176%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBiotin\u003c\/td\u003e\n\u003ctd\u003e5,000 mcg\u003c\/td\u003e\n\u003ctd\u003e16,666%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePantothenic Acid (from d-calcium pantothenate)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e2,000%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eZinc (citrate)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003e136%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSelenium\u003c\/td\u003e\n\u003ctd\u003e35 mcg\u003c\/td\u003e\n\u003ctd\u003e63%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCopper\u003c\/td\u003e\n\u003ctd\u003e1 mg\u003c\/td\u003e\n\u003ctd\u003e111%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eProprietary Blend: Gelatin (kosher), Hyaluronic Acid, and Collagen (from Chicken)\u003c\/td\u003e\n\u003ctd\u003e750 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established. Serving size: 2 capsules. Servings per container: 30 (60 capsules). Other ingredients: Talc, Silica, and Magnesium Stearate (Vegetable Source). The label states: \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow NutriSilk works\u003c\/h2\u003e\n\u003ch3\u003eBiotin (5,000 mcg)\u003c\/h3\u003e\n\u003cp\u003eBiotin is vitamin B7. Your body uses it as a helper for enzymes that process fats, carbohydrates and amino acids.† No upper limit has been set for biotin, because the Food and Nutrition Board found no evidence that it's toxic at high intakes (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Biotin-HealthProfessional\/\"\u003eNIH biotin fact sheet\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eNow the candid part. That same NIH fact sheet says biotin's reputation for hair, skin and nails rests, at best, on a few case reports and small studies, and the nail studies didn't report whether people were low in biotin to begin with. So think of biotin as covering a nutrient your body uses every day, not as a guarantee about your hair.\u003c\/p\u003e\n\u003ch3\u003eCollagen and hyaluronic acid (750 mg blend)\u003c\/h3\u003e\n\u003cp\u003eCollagen is the main structural protein in skin, and gelatin is collagen that has been cooked down. Hyaluronic acid is a sugar-based molecule your skin uses to hold on to water. NutriSilk's blend combines gelatin (kosher), hyaluronic acid and collagen from chicken, 750 mg in all.†\u003c\/p\u003e\n\u003cp\u003eWhat the research shows: a 2023 systematic review pooled 26 randomized trials with 1,721 participants and found that hydrolyzed collagen improved skin hydration and elasticity compared with placebo. The authors also found bias in several of those trials and called for larger studies (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37432180\/\"\u003ePu 2023\u003c\/a\u003e). For hyaluronic acid, a 12-week trial in 150 healthy adults found that 120 mg a day of oral sodium hyaluronate improved skin hydration and elasticity compared with placebo, with smaller effects at 60 mg a day. Six of its seven authors work for a company that makes hyaluronic acid (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41422283\/\"\u003eDolečková 2025\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eWhat it doesn't show: the label lists the blend as one 750 mg total without breaking out each ingredient, and the collagen trials used hydrolyzed collagen. So we can't tell you NutriSilk matches the doses in those studies. Think of the blend as a supporting cast for the vitamins and minerals.\u003c\/p\u003e\n\u003ch3\u003eZinc (citrate), copper and selenium\u003c\/h3\u003e\n\u003cp\u003eZinc helps hundreds of enzymes do their jobs, including the ones that build proteins and copy DNA when cells divide.† Copper is a helper for enzymes involved in making connective tissue (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Copper-HealthProfessional\/\"\u003eNIH copper fact sheet\u003c\/a\u003e).† NutriSilk uses zinc citrate. In a small randomized crossover study, 15 healthy adults given 10 mg of zinc without food absorbed about 61% of it from zinc citrate, about the same as from zinc gluconate, and about 50% from zinc oxide (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24259556\/\"\u003eWegmüller 2014\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003eZinc and copper are linked. Taking 50 mg or more of zinc a day for weeks can interfere with copper absorption (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Zinc-HealthProfessional\/\"\u003eNIH zinc fact sheet\u003c\/a\u003e). NutriSilk pairs 15 mg of zinc with 1 mg of copper, and that zinc sits well under the 40 mg daily upper limit for adults. Selenium (35 mcg, 63% DV) gets built into selenoproteins, including the glutathione peroxidase enzymes that are part of your body's own antioxidant system (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Selenium-HealthProfessional\/\"\u003eNIH selenium fact sheet\u003c\/a\u003e).†\u003c\/p\u003e\n\u003ch3\u003eNiacinamide, riboflavin, vitamin B6 and pantothenic acid\u003c\/h3\u003e\n\u003cp\u003eThese four B vitamins help your cells turn food into usable energy.† Niacinamide is the form of vitamin B3 that doesn't cause the hot, red \"niacin flush\" that nicotinic acid can (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\"\u003eNIH niacin fact sheet\u003c\/a\u003e). Vitamin B6, here as pyridoxine HCl, takes part in more than 100 enzyme reactions, most of them involved in processing protein, the raw material for keratin and collagen.† Pantothenic acid comes as d-calcium pantothenate, the most common supplement form, and your cells use it to make coenzyme A, which is central to burning fats and carbohydrates for fuel.†\u003c\/p\u003e\n\u003ch2\u003eHow to take NutriSilk\u003c\/h2\u003e\n\u003cp\u003eThe label directions: \"Take two capsules per day, as a dietary supplement.\" That's one serving, so a 60-capsule bottle lasts 30 days.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThe label doesn't say whether to take it with food. Pairing it with the same meal every day is the easiest way to remember it.\u003c\/li\u003e\n\u003cli\u003eThe 10 mg of riboflavin can turn your urine bright yellow. Riboflavin is a yellow vitamin, and your body passes what it doesn't use in urine (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Riboflavin-HealthProfessional\/\"\u003eNIH riboflavin fact sheet\u003c\/a\u003e).\u003c\/li\u003e\n\u003cli\u003eNutriSilk is not vegetarian. The blend contains gelatin and collagen from chicken.\u003c\/li\u003e\n\u003cli\u003eBiotin can throw off some lab tests. In a small study, six healthy adults taking 10 mg of biotin a day for a week saw interference in 9 of 23 biotin-based tests (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28973622\/\"\u003eLi 2017\u003c\/a\u003e). NutriSilk has 5 mg per serving, so tell your practitioner and the lab you take it before any blood work.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\/nutrisilk-hair-skin-nail-support\"\u003eSee the certificates of analysis for this product\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility sits right in it. The people who formulate, make and test NutriSilk work under one roof, and the owners work in the building too. The company has been owner-run since 2017. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow long does it take to notice a difference?\u003c\/h3\u003e\n\u003cp\u003eGive it about three months of daily use before you judge. Hair and nails grow slowly, and the hyaluronic acid trial above ran for 12 weeks.\u003c\/p\u003e\n\u003ch3\u003eCan I take NutriSilk with my multivitamin?\u003c\/h3\u003e\n\u003cp\u003eYou can, but check the totals first. If you take a daily multi such as our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-multi-cap-60ct\"\u003eWomen's Multi with KSM-66 ashwagandha\u003c\/a\u003e or \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-multi-vitamin-60-capsules\"\u003eMen's Multi daily multivitamin\u003c\/a\u003e, add up the zinc, niacin and vitamin B6 across both labels, and ask your practitioner if the combined amounts are right for you.\u003c\/p\u003e\n\u003ch3\u003eWhy are some of the Daily Values so high?\u003c\/h3\u003e\n\u003cp\u003eBecause some Daily Values are tiny. Biotin's DV is 30 mcg, so 5,000 mcg reads as 16,666%, and no upper limit has been set for biotin. The 20 mg of vitamin B6 is well under the 100 mg adult upper limit the NIH lists (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB6-HealthProfessional\/\"\u003eNIH vitamin B6 fact sheet\u003c\/a\u003e). The 250 mg of niacinamide is above the 35 mg upper limit the NIH lists for supplemental niacin. That limit was set based on the flushing nicotinic acid causes and applies to both forms, though niacinamide itself doesn't cause flushing. If you take other niacin products, or have questions about your total, ask your practitioner.\u003c\/p\u003e\n\u003ch3\u003eDo I need to stop NutriSilk before blood work?\u003c\/h3\u003e\n\u003cp\u003eAsk your practitioner, and tell the lab you take biotin. Biotin can interfere with some common lab tests, so your practitioner may want you to pause it first.\u003c\/p\u003e\n\u003ch3\u003eShould I take vitamin C with NutriSilk?\u003c\/h3\u003e\n\u003cp\u003eIt's a sensible pairing. Your body needs vitamin C to make collagen (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminC-Consumer\/\"\u003eNIH vitamin C fact sheet\u003c\/a\u003e), and NutriSilk contains none, so a vitamin C supplement such as \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-c-buffered-vitamin-c\"\u003eGood C buffered vitamin C\u003c\/a\u003e covers that side.†\u003c\/p\u003e\n\u003ch3\u003eIs NutriSilk safe with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, and bring the bottle so they can see every ingredient and amount.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\/nutrisilk-hair-skin-nail-support\"\u003eNutriSilk certificates of analysis, lot by lot\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\"\u003eCertificates of analysis for other Mt. Angel Vitamins products\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003ePu SY et al. Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis. Nutrients. 2023. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37432180\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDolečková I et al. Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults. Sci Rep. 2025. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41422283\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWegmüller R et al. Zinc absorption by young adults from supplemental zinc citrate is comparable with that from zinc gluconate and higher than from zinc oxide. J Nutr. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24259556\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eLi D et al. Association of Biotin Ingestion With Performance of Hormone and Nonhormone Assays in Healthy Adults. JAMA. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28973622\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424184090,"sku":"015-M1007","price":27.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1007REV05_ListingImage1.png?v=1770229271"},{"product_id":"inflameze-advanced-turmeric-joint","title":"Inflameze Advanced – Turmeric Joint Comfort Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eInflameze Advanced is a turmeric-based joint comfort supplement with 250 mg of Curcumin Complex from CurcuWIN™ in every 1-capsule serving, plus a 305 mg blend of boswellia standardized to 70% boswellic acids, bromelain, green tea extract, ginger root extract and Bioperine™ (a black pepper extract). Each bottle holds 60 vegetarian capsules. It supports joint comfort.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eInflameze Advanced is for people who want their knees, hips and shoulders to keep up with their plans: the 42-year-old training for a half marathon, the 50-something who still carries the canoe to the river.\u003c\/p\u003e\n\u003cp\u003eAging isn't optional. Getting old is. Joints are often where people first feel the years, and the habits that help most (strength work, walking, sleep, decent food) pay off when you start in your 30s and 40s. It's one small, steady part of that routine, not a stand-in for it.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Inflameze Advanced\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports joint comfort, with 250 mg of curcumin complex from CurcuWIN in every capsule.†\u003c\/li\u003e\n\u003cli\u003eUses CurcuWIN, a curcumin form made to dissolve in water, so more curcumin reaches the bloodstream than from standard, unformulated curcumin extract.†\u003c\/li\u003e\n\u003cli\u003ePairs curcumin with boswellia standardized to 70% boswellic acids and bromelain from pineapple.†\u003c\/li\u003e\n\u003cli\u003eProvides antioxidant polyphenols from turmeric and green tea extract.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCurcumin Complex (from CurcuWIN™)\u003c\/td\u003e\n\u003ctd\u003e250 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eProprietary Blend, containing: \u003cem\u003eBoswellia serrata\u003c\/em\u003e Standardized Extract (Standardized to 70% Boswellic Acids), Bromelain (from pineapple, \u003cem\u003eAnanas comosus\u003c\/em\u003e), Green Tea Standardized Extract (Standardized to 50% polyphenols, 35% catechins, and 15% EGCG), Ginger Root 4:1 Extract, and Bioperine™\u003c\/td\u003e\n\u003ctd\u003e305 mg (whole blend)\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 1 vegetarian capsule. Each bottle holds 60 capsules, so 60 one-capsule servings. Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), organic rice concentrate, and organic rice extract. The label states: \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" It also states: \"This product does not contain genetically modified materials.\"\u003c\/p\u003e\n\u003ch2\u003eHow Inflameze Advanced works\u003c\/h2\u003e\n\u003cp\u003eStraight talk first: the research below tests single ingredients or pairs, not Inflameze Advanced itself, usually in other forms and amounts. The 305 mg blend is listed as one total, so we don't guess at individual amounts.\u003c\/p\u003e\n\u003ch3\u003eCurcumin Complex from CurcuWIN: 250 mg\u003c\/h3\u003e\n\u003cp\u003eCurcumin is the yellow-orange compound in turmeric root. Its weak spot is plumbing: it barely dissolves in water, so most of a standard curcumin extract passes straight through. CurcuWIN disperses curcumin on a water-soluble carrier with cellulose derivatives, plus antioxidants that help keep it from breaking down, so more of it dissolves in the watery gut where it can be absorbed.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24461029\/\"\u003ea crossover study in 12 healthy young adults\u003c\/a\u003e, a formulation built that way, supplied by OmniActive (the CurcuWIN trademark owner), put 45.9 times more total curcuminoids into the blood over 12 hours than a standard, unformulated curcumin extract, milligram for milligram of curcuminoids. The limits: one dose, 12 people averaging 23 years old (11 of them men), and blood levels rather than how anyone felt. Turmeric extract was 20 to 28% of that formulation, the rest being carrier, cellulose derivatives and antioxidants; our label lists 250 mg of the whole complex, without a separate curcuminoid figure.\u003c\/p\u003e\n\u003cp\u003eOn results, \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37460208\/\"\u003ean umbrella review of meta-analyses of randomized trials\u003c\/a\u003e rated curcumin's effect on muscle soreness after muscle-damaging exercise as moderate-certainty evidence, across many curcumin forms and doses.† The closest test of this ingredient is smaller and more mixed. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31340534\/\"\u003ean 8-week placebo-controlled trial of CurcuWIN in 63 active young adults\u003c\/a\u003e, people took 250 mg or 1,000 mg of CurcuWIN a day (50 or 200 mg of curcuminoids in that study). By weight, that's the Curcumin Complex in one or four Inflameze Advanced capsules. After a downhill run, the 1,000 mg dose limited the drop in some, but not all, strength measures compared with placebo, though its lower soreness scores didn't reach statistical significance. The 250 mg dose showed no advantage. Background, not a promise for this capsule.\u003c\/p\u003e\n\u003ch3\u003eBoswellia serrata extract, standardized to 70% boswellic acids\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eBoswellia serrata\u003c\/em\u003e, sometimes called Indian frankincense, is a tree native to India, and its gum resin is the source of boswellic acids. \"Standardized to 70%\" means the extract is made to contain that share of boswellic acids, the resin's signature compounds.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15643550\/\"\u003ea crossover study in healthy men\u003c\/a\u003e, taking a different boswellia extract (786 mg) with a high-fat meal raised blood levels of several boswellic acids several-fold compared with an empty stomach. That's why we suggest taking Inflameze Advanced with a meal. And in \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27879642\/\"\u003ea 12-week randomized trial in 47 healthy male cyclists averaging 46 years old\u003c\/a\u003e, adding a curcumin and boswellia tablet to a Mediterranean diet cut advanced glycation end products (markers tied to oxidative stress) about 42%, while diet alone didn't.† The limits: a small pilot study with no placebo, a different curcumin form and amount, and blood markers aren't how your knees feel.\u003c\/p\u003e\n\u003ch3\u003eBioperine (black pepper extract)\u003c\/h3\u003e\n\u003cp\u003eBioperine is a black pepper extract whose active compound, piperine, slows one of the chemical tagging steps the gut wall and liver use to clear curcumin. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9619120\/\"\u003ea study in healthy volunteers\u003c\/a\u003e, 2 grams of plain curcumin alone left blood levels undetectable or very low, while adding 20 mg of piperine raised curcumin's bioavailability by 2,000%. That study used plain curcumin, not CurcuWIN, and we haven't found one testing the two together. They work on different steps: CurcuWIN helps curcumin dissolve, and piperine slows its clearance.\u003c\/p\u003e\n\u003ch3\u003eBromelain, green tea and ginger\u003c\/h3\u003e\n\u003cp\u003eBromelain is a group of protein-digesting enzymes from pineapple, long paired with boswellia and turmeric in joint formulas, including our original Inflameze. The label gives no enzyme activity rating, so we don't quote one.\u003c\/p\u003e\n\u003cp\u003eThe green tea extract is standardized to 50% polyphenols, 35% catechins and 15% EGCG, and those polyphenols are antioxidants.† The label doesn't list caffeine or say whether the extract is decaffeinated, so if you're sensitive, take your second dose with an early dinner.\u003c\/p\u003e\n\u003cp\u003eGinger is the familiar kitchen root, and \"4:1\" means four parts ginger root were concentrated into one part extract. Its individual amount in the blend isn't listed, so we make no specific claim for it.\u003c\/p\u003e\n\u003ch2\u003eHow to take Inflameze Advanced\u003c\/h2\u003e\n\u003cp\u003eThe label directions: \"One to two capsules twice daily, as a dietary supplement.\" That's 2 to 4 capsules a day. Our suggestion: start with one capsule at breakfast and one at dinner.\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. If you take prescription medication, including blood thinners, show your practitioner or pharmacist the Supplement Facts panel before you start.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cp\u003eWe've been making supplements in Oregon since 1974. Here's what stands behind every bottle of Inflameze Advanced.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Inflameze Advanced has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps formulators, makers and testers under one roof, and the owners work in the building too. We've been making supplements for 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many Inflameze Advanced capsules should I take a day?\u003c\/h3\u003e\n\u003cp\u003ePer the label, one to two capsules twice daily (2 to 4 a day). Two capsules give you 500 mg of Curcumin Complex from CurcuWIN and 610 mg of the blend; four give you 1,000 mg and 1,220 mg. A 60-capsule bottle lasts 30 days at two a day or 15 days at four.\u003c\/p\u003e\n\u003ch3\u003eShould I take Inflameze Advanced with food?\u003c\/h3\u003e\n\u003cp\u003eWe suggest it. The label doesn't require food, but boswellic acids absorbed several-fold better with a high-fat meal in the study above.\u003c\/p\u003e\n\u003ch3\u003eHow long before I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eThere's no set timeline, and we won't make one up. The longer studies above ran 8 to 12 weeks, so take it steadily at the label's dose and judge it by your normal week: the run, the yard work, the stairs.†\u003c\/p\u003e\n\u003ch3\u003eWhich Inflameze is right for me?\u003c\/h3\u003e\n\u003cp\u003eThe original \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/inflameze-botanical-joint-support\"\u003eInflameze\u003c\/a\u003e spreads each capsule across seven ingredients, including 50 mg of Curcumin C3 Complex. Inflameze Advanced centers on 250 mg of CurcuWIN curcumin complex. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/inflameze-ultra-caps-50ct\"\u003eInflameze Ultra\u003c\/a\u003e has 500 mg of Curcumin C3 Complex per 2-capsule serving, with ParActin® andrographis, organic ginger root and BioPerine®.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Joint Solution Advanced or MSM 2000?\u003c\/h3\u003e\n\u003cp\u003eYou can, but count the overlap. A full 4-capsule serving of \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-support-advanced\"\u003eJoint Solution Advanced\u003c\/a\u003e adds 400 mg of boswellia extract, 200 mg of bromelain and 100 mg of Curcumin C3 Complex, and its label states it contains glucosamine from crab shell. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/msm-2000mg-joint-health-support\"\u003eMSM 2000\u003c\/a\u003e is a single ingredient (2,000 mg of MSM per tablet), so nothing repeats. Run any stack past your practitioner.\u003c\/p\u003e\n\u003ch3\u003eIs Inflameze Advanced safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, and bring the Supplement Facts panel. Piperine from Bioperine changes how the body processes some compounds, so every ingredient is worth checking against your medication list.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-mobility-stack-inflameze-msm\"\u003eWhat's in the Joint + Mobility Stack\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eJäger R et al. Comparative absorption of curcumin formulations. Nutr J. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24461029\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eTalebi S et al. Nutritional interventions for exercise-induced muscle damage: an umbrella review of systematic reviews and meta-analyses of randomized trials. Nutr Rev. 2024. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37460208\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eJäger R et al. Eight Weeks of a High Dose of Curcumin Supplementation May Attenuate Performance Decrements Following Muscle-Damaging Exercise. Nutrients. 2019. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31340534\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSterk V et al. Effect of food intake on the bioavailability of boswellic acids from a herbal preparation in healthy volunteers. Planta Med. 2004. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15643550\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eChilelli NC et al. Curcumin and Boswellia serrata Modulate the Glyco-Oxidative Status and Lipo-Oxidation in Master Athletes. Nutrients. 2016. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27879642\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eShoba G et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9619120\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424151322,"sku":"015-M1009","price":31.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1009_REV03_Listing_Image_1.png?v=1738258346"},{"product_id":"maximum-male-vital-energy","title":"Maximum Male with KSM-66 Ashwagandha – Energy and Stress Support | 60 Tablets","description":"\u003cp\u003e\u003cstrong\u003eMaximum Male is a men's herbal supplement with 300 mg of KSM-66 ashwagandha extract, 600 mg of Tribulus terrestris fruit and 100 mg of horny goat weed extract (standardized to 10% icariin) in every 2-tablet serving, plus a 395 mg blend of muira puama, ginkgo, ginger and freeze-dried oysters. Each bottle holds 60 tablets, a 30-day supply, to support a healthy stress response and everyday energy.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMaximum Male is for men in their 30s, 40s and beyond who are juggling a job, a family and a training plan. Two tablets a day, no caffeine, no ten-step stack.\u003c\/p\u003e\n\u003cp\u003eAging isn't optional. Getting old is. The habits that keep a man strong at 70 (lifting, sleep, real food, a lid on stress) are easiest to build now. Maximum Male is one small part of that routine, not a shortcut around it.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Maximum Male\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports a healthy response to everyday stress, including healthy cortisol levels, with 300 mg of KSM-66 ashwagandha per serving.†\u003c\/li\u003e\n\u003cli\u003eSupports your training, with ashwagandha studied for strength and endurance in adults who exercise.†\u003c\/li\u003e\n\u003cli\u003eSupports steady everyday energy for men who work hard and train hard.†\u003c\/li\u003e\n\u003cli\u003eRounds out the formula with tribulus fruit, horny goat weed, muira puama, ginkgo and ginger, herbs with long histories of traditional use.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cem\u003eTribulus terrestris\u003c\/em\u003e Fruit\u003c\/td\u003e\n\u003ctd\u003e600 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cem\u003eWithania somnifera\u003c\/em\u003e Extract (from KSM-66® Ashwagandha)\u003c\/td\u003e\n\u003ctd\u003e300 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHorny Goat Weed Extract (\u003cem\u003eEpimedium sagattatum\u003c\/em\u003e) (standardized to 10% icariin)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eProprietary Blend: Muira Puama 4:1 Extract (\u003cem\u003ePtychopetalum olacoides\u003c\/em\u003e root), \u003cem\u003eGinkgo biloba\u003c\/em\u003e Leaf Extract (standardized to 24% ginkgo flavonglycosides and 6% triterpene lactones), Ginger Root (\u003cem\u003eZingiber officinale\u003c\/em\u003e), and Freeze Dried Oysters\u003c\/td\u003e\n\u003ctd\u003e395 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 2 tablets. Servings per container: 30 (60 tablets per bottle). Other ingredients: Cellulose, silica, magnesium stearate (vegetable source), and vegetable stearate. The label states: \"NO corn, soy, salt, yeast, wheat, milk \u0026amp; egg products, sugar, starch, or preservatives.\" Allergen statement: \"Contains Molluscan Shellfish (from oysters).\"\u003c\/p\u003e\n\u003ch2\u003eHow Maximum Male works\u003c\/h2\u003e\n\u003cp\u003eStraight talk: the research below is on single ingredients, not on Maximum Male as a finished formula, and we'll say where it falls short.\u003c\/p\u003e\n\u003ch3\u003eKSM-66 ashwagandha: 300 mg\u003c\/h3\u003e\n\u003cp\u003eAshwagandha (\u003cem\u003eWithania somnifera\u003c\/em\u003e) is a small shrub in the nightshade family, and its root has a long history in India's Ayurvedic tradition. KSM-66 is a branded ashwagandha root extract made by Ixoreal Biomed, and it's the extract used in published trials, including the strength study below.\u003c\/p\u003e\n\u003cp\u003eThe stress side, in plain English: when you're under pressure, your body releases cortisol, the hormone that keeps you alert and running. That's useful in short bursts and wearing when it never shuts off. Ashwagandha is studied as an adaptogen, an herb that helps the body handle that load. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38140274\/\"\u003eA systematic review of 9 clinical studies in people under stress\u003c\/a\u003e found ashwagandha lowered cortisol over 30 to 112 days, with no significant side effects reported.† The candid part: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40746175\/\"\u003ea 2025 meta-analysis\u003c\/a\u003e pooled 7 trials and found cortisol dropped by about 1.16 µg\/dL on average, but across 6 trials that asked people how stressed they felt, the change wasn't statistically significant. The cortisol result holds up in both reviews; the \"I feel calmer\" result is less clear.\u003c\/p\u003e\n\u003cp\u003eThe training side: in \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26609282\/\"\u003ean 8-week randomized trial in 57 healthy men\u003c\/a\u003e aged 18 to 50 with little lifting experience, everyone followed the same resistance program while taking 300 mg of KSM-66 twice a day or a placebo. Bench-press max went up 46 kg in the ashwagandha group versus 26 kg with placebo.† Testosterone rose by 96 ng\/dL versus 18 ng\/dL with placebo, though end-of-study levels weren't statistically different between the groups. More broadly, \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42356302\/\"\u003ea 2026 meta-analysis of 13 trials and 599 people\u003c\/a\u003e found ashwagandha improved exercise performance on average, most consistently for aerobic endurance; strength effects were positive but less certain.†\u003c\/p\u003e\n\u003cp\u003eThe fine print: one serving of Maximum Male has 300 mg of KSM-66. The strength trial used 600 mg a day, and that 2026 meta-analysis found 500 to 600 mg a day was the best-supported range. Read these studies as the case for the ingredient, not a promise for a single serving.\u003c\/p\u003e\n\u003ch3\u003eTribulus terrestris fruit: 600 mg\u003c\/h3\u003e\n\u003cp\u003eTribulus is a low, sprawling plant with spiny, burr-like fruit, and that fruit has been used as a tonic in traditional medicine since ancient times. The Maximum Male label lists 600 mg of tribulus fruit per serving.\u003c\/p\u003e\n\u003cp\u003eYou'll often see tribulus sold as a testosterone booster. The research doesn't back that up. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24559105\/\"\u003eA systematic review of human and animal studies\u003c\/a\u003e concluded tribulus appears ineffective for raising testosterone in people; the only human increases it found came when tribulus was part of a combined supplement. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15994038\/\"\u003ea 4-week randomized study of 21 healthy men aged 20 to 36\u003c\/a\u003e, tribulus extract didn't change testosterone, androstenedione or luteinizing hormone compared with placebo. So tribulus is here as part of a traditional men's formula, and we won't sell it to you as a testosterone booster.\u003c\/p\u003e\n\u003ch3\u003eHorny goat weed extract: 100 mg\u003c\/h3\u003e\n\u003cp\u003eHorny goat weed is a leafy \u003cem\u003eEpimedium\u003c\/em\u003e plant from traditional Chinese practice. Our extract is standardized to 10% icariin, the flavonoid researchers track in this plant. Human research on horny goat weed is thin, so we make no specific claims for it.\u003c\/p\u003e\n\u003ch3\u003eThe 395 mg blend: muira puama, ginkgo, ginger and oysters\u003c\/h3\u003e\n\u003cp\u003eMuira puama is the root of a small Amazonian tree used as a tonic in Brazilian folk tradition; \"4:1\" means four parts root were concentrated into one part extract. Ginkgo extract comes from the fan-shaped leaves of the ginkgo tree, standardized here to 24% ginkgo flavonglycosides and 6% triterpene lactones. The freeze-dried oysters are why the label carries a shellfish allergen statement. Oysters are known as a food source of zinc, but the Supplement Facts panel doesn't list zinc, so don't count on Maximum Male for it.\u003c\/p\u003e\n\u003cp\u003eThe label gives the blend's 395 mg total, not each ingredient's share, so we don't make claims for any of the four on its own.\u003c\/p\u003e\n\u003ch2\u003eHow to take Maximum Male\u003c\/h2\u003e\n\u003cp\u003eThe label directions: \"Take two tablets per day, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eOur suggestions: take both tablets together, or one in the morning and one in the evening (the strength trial split its doses between waking and bedtime). The label doesn't mention food, so that's your call. Either way, take it daily: the strength trial ran 8 weeks, and the cortisol studies ran 30 to 112 days.\u003c\/p\u003e\n\u003cp\u003eMaximum Male contains molluscan shellfish (from oysters). Skip it if you avoid shellfish. Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cp\u003eWe've been making supplements in Oregon since 1974. Here's what stands behind the two tablets you take each day.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Maximum Male has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps formulators, makers and testers under one roof, and the owners work in the building too. After 52 years of making supplements, we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many Maximum Male tablets should I take a day?\u003c\/h3\u003e\n\u003cp\u003eTwo tablets a day, per the label. A 60-tablet bottle holds 30 two-tablet servings, a 30-day supply.\u003c\/p\u003e\n\u003ch3\u003eDoes Maximum Male raise testosterone?\u003c\/h3\u003e\n\u003cp\u003eWe don't claim it does. The strongest evidence in this formula is for ashwagandha: in the 8-week strength trial above, men taking 600 mg a day of KSM-66 (twice the amount in one serving) saw testosterone rise more than men on placebo, though end-of-study levels weren't statistically different. Tribulus, despite its reputation, didn't change testosterone in healthy young men.\u003c\/p\u003e\n\u003ch3\u003eHow long before I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eGive it about two months of daily use.† The studies above ran 8 weeks for strength and 30 to 112 days for cortisol, so a week or two is too soon to judge.\u003c\/p\u003e\n\u003ch3\u003eCan I take Maximum Male with Men's Multi or Men's 50+?\u003c\/h3\u003e\n\u003cp\u003eYes. A 2-capsule serving of \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-multi-vitamin-60-capsules\"\u003eMen's Multi\u003c\/a\u003e or \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-50-plus-multivitamin\"\u003eMen's 50+ Multivitamin\u003c\/a\u003e has 300 mg of KSM-66 ashwagandha, the same extract and amount as Maximum Male. Taking both gets you to 600 mg a day, the daily amount used in the strength trial. If you take medication, run the combination past your practitioner first.\u003c\/p\u003e\n\u003ch3\u003eIs there caffeine in Maximum Male?\u003c\/h3\u003e\n\u003cp\u003eNo. The label lists no caffeine, so you can take it whenever it suits your day. If you want caffeine in a formula, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-energy-stamina-blood-sugar\"\u003eGood Energy+\u003c\/a\u003e has 100 mg per 2-capsule serving.\u003c\/p\u003e\n\u003ch3\u003eIs Maximum Male vegetarian?\u003c\/h3\u003e\n\u003cp\u003eNo. It contains freeze-dried oysters, and the label states \"Contains Molluscan Shellfish (from oysters).\"\u003c\/p\u003e\n\u003ch3\u003eIs Maximum Male safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, and bring the Supplement Facts panel so they can check every ingredient against your medication list.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eDella Porta M et al. Effects of Withania somnifera on Cortisol Levels in Stressed Human Subjects: A Systematic Review. Nutrients. 2023. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38140274\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAlbalawi AA. Dual impact of Ashwagandha: Significant cortisol reduction but no effects on perceived stress - A systematic review and meta-analysis. Nutr Health. 2025. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40746175\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWankhede S et al. Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. J Int Soc Sports Nutr. 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26609282\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eLi X et al. Effects of Withania somnifera (Ashwagandha) Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis. Nutrients. 2026. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42356302\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eQureshi A et al. A systematic review on the herbal extract Tribulus terrestris and the roots of its putative aphrodisiac and performance enhancing effect. J Diet Suppl. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24559105\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eNeychev VK et al. The aphrodisiac herb Tribulus terrestris does not influence the androgen production in young men. J Ethnopharmacol. 2005. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15994038\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424085786,"sku":"015-M1012","price":31.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1012_REV02_Necktag.png?v=1738258383"},{"product_id":"prost-tech-plus-prostate-support","title":"Prost-Tech Plus – Supports Normal Prostate Function | 60 Vegetarian Tablets","description":"\u003cp\u003e\u003cstrong\u003eProst-Tech Plus is a daily men's supplement that supports normal prostate function.† Each 2-tablet serving provides 500 mg pumpkin seed extract, 300 mg saw palmetto berry extract, 100 mg African pygeum bark extract and a 613 mg blend with beta-sitosterol, nettle root and lycopene, plus 22 mg zinc and 55 mcg selenium. One bottle holds 60 vegetarian tablets, or 30 servings.\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eProst-Tech Plus is for men who would rather build a steady habit than wait for a reason. It puts four plant extracts with a long history in men's formulas (pumpkin seed, saw palmetto, pygeum and nettle root) next to plant sterols and the minerals your body uses to build its antioxidant enzymes.† Think of it as the nutrition side of a bigger plan.\u003c\/p\u003e\r\n\u003cp\u003eWe've been making supplements in Oregon since 1974, and we'd rather explain a formula than hype it. So here it is, line by line.\u003c\/p\u003e\r\n\u003ch2\u003eWhy people take Prost-Tech Plus\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eTo support normal prostate function with pumpkin seed, saw palmetto, African pygeum and stinging nettle root extracts in one daily routine.†\u003c\/li\u003e\r\n\u003cli\u003eFor plant sterols from two sources: a beta-sitosterol phytosterol complex and pygeum bark extract standardized to 20% phytosterols.†\u003c\/li\u003e\r\n\u003cli\u003eTo cover zinc at 22 mg (200% DV), a mineral involved in normal immune function, protein and DNA synthesis, and cell division.†\u003c\/li\u003e\r\n\u003cli\u003eFor selenium and copper, which the body builds into enzymes that help protect cells from oxidative damage.†\u003c\/li\u003e\r\n\u003cli\u003eFor antioxidant support from vitamin C and lycopene, plus vitamin B6 for normal protein metabolism.†\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\r\n\u003ctable\u003e\r\n\u003cthead\u003e\r\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\r\n\u003c\/thead\u003e\r\n\u003ctbody\u003e\r\n\u003ctr\u003e\n\u003ctd\u003eVitamin C (from Ascorbic Acid)\u003c\/td\u003e\n\u003ctd\u003e90 mg\u003c\/td\u003e\n\u003ctd\u003e100%\u003c\/td\u003e\n\u003c\/tr\u003e\r\n\u003ctr\u003e\n\u003ctd\u003eVitamin B6 (from Pyridoxine HCl)\u003c\/td\u003e\n\u003ctd\u003e8.5 mg\u003c\/td\u003e\n\u003ctd\u003e500%\u003c\/td\u003e\n\u003c\/tr\u003e\r\n\u003ctr\u003e\n\u003ctd\u003eZinc (gluconate)\u003c\/td\u003e\n\u003ctd\u003e22 mg\u003c\/td\u003e\n\u003ctd\u003e200%\u003c\/td\u003e\n\u003c\/tr\u003e\r\n\u003ctr\u003e\n\u003ctd\u003eSelenium (L-selenomethionine)\u003c\/td\u003e\n\u003ctd\u003e55 mcg\u003c\/td\u003e\n\u003ctd\u003e100%\u003c\/td\u003e\n\u003c\/tr\u003e\r\n\u003ctr\u003e\n\u003ctd\u003eCopper (gluconate)\u003c\/td\u003e\n\u003ctd\u003e0.9 mg\u003c\/td\u003e\n\u003ctd\u003e100%\u003c\/td\u003e\n\u003c\/tr\u003e\r\n\u003ctr\u003e\n\u003ctd\u003ePumpkin Seed Extract (\u003cem\u003eCurcubita pepo\u003c\/em\u003e seed, from EFLA® Curcubitae)\u003c\/td\u003e\n\u003ctd\u003e500 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\r\n\u003ctr\u003e\n\u003ctd\u003eSaw Palmetto Berry Extract (\u003cem\u003eSerenoa repens\u003c\/em\u003e, standardized to 25% fatty acids)\u003c\/td\u003e\n\u003ctd\u003e300 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\r\n\u003ctr\u003e\n\u003ctd\u003eAfrican Pygeum Bark Extract (\u003cem\u003ePygeum africanum\u003c\/em\u003e, standardized to 20% phytosterols)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\r\n\u003ctr\u003e\n\u003ctd\u003eProprietary Blend: Red Clover Extract (\u003cem\u003eTrifolium pretense\u003c\/em\u003e Aerial Parts standardized to minimum 36% Isoflavones), Beta-Sitosterol Phytosterol Complex from Plant Sterols, (contains minimums beta-sitosterol, campesterol, and stigmasterol), Stinging Nettle Root 4:1 Extract (\u003cem\u003eUrtica dioica\u003c\/em\u003e), L-Tyrosine, and Lycopene (natural)\u003c\/td\u003e\n\u003ctd\u003e613 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\r\n\u003c\/tbody\u003e\r\n\u003c\/table\u003e\r\n\u003cp\u003e*Daily Value not established. Serving size: 2 vegetarian tablets. Servings per container: 30. Other ingredients: Calcium Carbonate, Plant Cellulose, Tomato Powder, and Silica. EFLA® Curcubitae is a registered trademark of Frutarom Switzerland Ltd.\u003c\/p\u003e\r\n\u003ch2\u003eHow Prost-Tech Plus works\u003c\/h2\u003e\r\n\u003cp\u003eOne honest note first. Most human studies of saw palmetto, pygeum, nettle root and pumpkin seed enrolled men already under a doctor's care, so we don't use those results to make promises about this product. What follows describes the ingredients, not Prost-Tech Plus as a finished product.\u003c\/p\u003e\r\n\u003ch3\u003ePumpkin seed extract (500 mg)\u003c\/h3\u003e\r\n\u003cp\u003eThe largest individually listed ingredient in the formula: a concentrated extract of pumpkin seeds, which naturally carry plant sterols and fatty acids. The front label calls it EFLA®940, a trademarked extract. The label doesn't print a standardization marker for it, so we won't invent one.\u003c\/p\u003e\r\n\u003ch3\u003eSaw palmetto berry extract (300 mg)\u003c\/h3\u003e\r\n\u003cp\u003eSaw palmetto is a low, scrubby palm native to the southeastern United States, and its berries are rich in fatty acids and plant sterols. This extract is standardized to 25% fatty acids, which works out to about 75 mg of fatty acids per serving. Standardizing means each lot delivers a measured amount of the fraction researchers study. Its human results have been mixed, so here it's one part of the formula, not the whole thing.\u003c\/p\u003e\r\n\u003ch3\u003eAfrican pygeum bark extract (100 mg)\u003c\/h3\u003e\r\n\u003cp\u003ePygeum comes from the bark of \u003cem\u003ePygeum africanum\u003c\/em\u003e (also called \u003cem\u003ePrunus africana\u003c\/em\u003e), an evergreen tree of African mountain forests. The extract is standardized to 20% phytosterols, or about 20 mg of plant sterols per serving. Like saw palmetto, it has a long track record in men's formulas, and most of its human research involves men under medical care.\u003c\/p\u003e\r\n\u003ch3\u003eThe 613 mg blend: plant sterols, nettle root, red clover, L-tyrosine and lycopene\u003c\/h3\u003e\r\n\u003cp\u003eBecause this is a proprietary blend, the label lists the combined 613 mg rather than each ingredient's amount.\u003c\/p\u003e\r\n\u003cul\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eBeta-sitosterol phytosterol complex.\u003c\/strong\u003e Plant sterols are cholesterol-shaped compounds found in nuts, seeds, grains and vegetable oils. The label notes this complex contains minimum amounts of beta-sitosterol, campesterol and stigmasterol.\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eStinging nettle root 4:1 extract.\u003c\/strong\u003e Roughly four parts root go into one part extract. In a lab study using human prostate tissue membranes, a water-based nettle root extract blocked a hormone-carrying protein called SHBG from binding to its receptor, more strongly as the dose rose (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7700987\/\"\u003eHryb et al., Planta Medica\u003c\/a\u003e). That's a test-tube result, the label doesn't say how this extract was made, and it tells us nothing certain about what happens in your body.\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eRed clover extract.\u003c\/strong\u003e Made from the aerial parts (the flowers, leaves and stems above ground) and standardized to at least 36% isoflavones, a family of plant compounds.\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eL-tyrosine.\u003c\/strong\u003e An amino acid your body uses to build proteins and to make dopamine, norepinephrine and thyroid hormones.\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eLycopene.\u003c\/strong\u003e The red carotenoid in tomatoes. Lycopene from fresh, raw tomatoes is poorly absorbed, while processed tomato foods and tomato juice heated in oil deliver more (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11880563\/\"\u003eRichelle et al., Journal of Nutrition\u003c\/a\u003e). Translation: it likes a little fat, which fits the label's with-meals direction.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch3\u003eZinc, selenium and copper\u003c\/h3\u003e\r\n\u003cp\u003e\u003cstrong\u003eZinc (22 mg, as zinc gluconate).\u003c\/strong\u003e Zinc is involved in immune function, protein and DNA synthesis, and cell division.† We use gluconate, a water-soluble form. In a randomized crossover study in 15 healthy adults given 10 mg zinc doses without food, about 61% of the zinc from zinc gluconate was absorbed, compared with about 50% from zinc oxide (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24259556\/\"\u003eWegmüller et al., Journal of Nutrition\u003c\/a\u003e). 22 mg sits under the 40 mg a day upper limit for adults listed in the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Zinc-HealthProfessional\/\"\u003eNIH zinc fact sheet\u003c\/a\u003e, a limit that counts zinc from food too.\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eSelenium (55 mcg, as L-selenomethionine).\u003c\/strong\u003e Selenomethionine is the main form of selenium in food, and 55 mcg matches the adult RDA in the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Selenium-HealthProfessional\/\"\u003eNIH selenium fact sheet\u003c\/a\u003e. The body absorbs most forms of selenium well, but it holds on to organic forms like selenomethionine more readily than inorganic ones (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20200264\/\"\u003eFairweather-Tait et al., American Journal of Clinical Nutrition\u003c\/a\u003e). Selenium is built into selenoproteins, some of which help protect cells from oxidative damage.†\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eCopper (0.9 mg, as copper gluconate).\u003c\/strong\u003e Copper is part of superoxide dismutase, one of the body's main antioxidant enzymes (\u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Copper-HealthProfessional\/\"\u003eNIH copper fact sheet\u003c\/a\u003e).† Zinc and copper are worth watching together: taken at 50 mg a day or more for weeks, zinc can interfere with copper absorption. The 22 mg here is well below that, and the formula includes copper too.\u003c\/p\u003e\r\n\u003ch3\u003eVitamin C and vitamin B6\u003c\/h3\u003e\r\n\u003cp\u003eVitamin C (90 mg, as ascorbic acid) matches the RDA for adult men in the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminC-HealthProfessional\/\"\u003eNIH vitamin C fact sheet\u003c\/a\u003e. Your body uses it to make collagen and as an antioxidant.† Vitamin B6 (8.5 mg, as pyridoxine HCl) takes part in more than 100 enzyme reactions, mostly in protein metabolism.† That's well under the 100 mg adult upper limit in the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB6-HealthProfessional\/\"\u003eNIH vitamin B6 fact sheet\u003c\/a\u003e.\u003c\/p\u003e\r\n\u003ch2\u003eHow to take Prost-Tech Plus\u003c\/h2\u003e\r\n\u003cp\u003eThe label's directions: \"One tablet twice daily with meals, as a dietary supplement.\"\u003c\/p\u003e\r\n\u003cp\u003eThat's two tablets a day, one full serving, so a 60-tablet bottle is a 30-day supply. Breakfast and dinner make an easy anchor.\u003c\/p\u003e\r\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. Prost-Tech Plus doesn't replace the prostate checkups your doctor recommends.\u003c\/p\u003e\r\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot of pumpkin seed, saw palmetto, pygeum and everything else for identity, potency, heavy metals and microbes.\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Prost-Tech Plus has one.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 in the Willamette Valley, and our UL-certified cGMP facility keeps formulators, makers and testers under one roof. The owners work in the building too. The company has been making supplements for 52 years, and we're not getting old either.\u003c\/p\u003e\r\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\r\n\u003ch3\u003eHow do I take Prost-Tech Plus?\u003c\/h3\u003e\r\n\u003cp\u003eTake one tablet twice daily with meals, as the label directs. That's one 2-tablet serving per day, so the 60-tablet bottle lasts 30 days.\u003c\/p\u003e\r\n\u003ch3\u003eShould I take Prost-Tech Plus with food?\u003c\/h3\u003e\r\n\u003cp\u003eYes, the label says to take it with meals. Lycopene and plant sterols dissolve in fat, not water, and lycopene is absorbed better from tomato foods heated in oil than from raw tomatoes. One tablet at each of two meals also spreads the serving across your day.\u003c\/p\u003e\r\n\u003ch3\u003eHow long until I notice anything?\u003c\/h3\u003e\r\n\u003cp\u003eThink in months, not days. Prost-Tech Plus is built for steady, daily support of normal prostate function,† not a quick, noticeable effect, and most research on these ingredients runs for weeks to months. Take it consistently and keep up with your regular checkups.\u003c\/p\u003e\r\n\u003ch3\u003eCan I take Prost-Tech Plus with a Mt. Angel multivitamin?\u003c\/h3\u003e\r\n\u003cp\u003ePossibly, but check the zinc first. Prost-Tech Plus has 22 mg of zinc, and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-multi-vitamin-60-capsules\"\u003eMen's Multi daily multivitamin\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-50-plus-multivitamin\"\u003eMen's 50+ Multivitamin\u003c\/a\u003e each add 15 mg, for 37 mg from supplements alone. The adult upper limit is 40 mg a day from food and supplements combined, so talk with your practitioner before taking both every day. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/maximum-male-vital-energy\"\u003eMaximum Male with tribulus and KSM-66 ashwagandha\u003c\/a\u003e doesn't list zinc or selenium on its Supplement Facts panel. Its label notes it contains molluscan shellfish (from oysters).\u003c\/p\u003e\r\n\u003ch3\u003eIs Prost-Tech Plus safe to take with prescription medication?\u003c\/h3\u003e\r\n\u003cp\u003eAsk your healthcare practitioner or pharmacist before you start. Bring the bottle so they can review the full label, including the saw palmetto, red clover isoflavones and zinc.\u003c\/p\u003e\r\n\u003ch3\u003eWhy aren't all of the ingredient amounts listed?\u003c\/h3\u003e\r\n\u003cp\u003eFive ingredients share a 613 mg proprietary blend, so the label gives the blend total. Everything else, including the pumpkin seed, saw palmetto and pygeum extracts and all five vitamins and minerals, is listed with its exact amount.\u003c\/p\u003e\r\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/maximum-male-vital-energy\"\u003eMaximum Male, a daily men's formula with tribulus and ashwagandha\u003c\/a\u003e\u003c\/li\u003e\r\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-multi-vitamin-60-capsules\"\u003eMen's Multi, a two-capsule daily multivitamin for men\u003c\/a\u003e\u003c\/li\u003e\r\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/yourheart-nutrients-heart-health\"\u003eYourHeart Nutrients, a heart and circulation formula with a beta-sitosterol phytosterol complex\u003c\/a\u003e\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch2\u003eReferences\u003c\/h2\u003e\r\n\u003col\u003e\r\n\u003cli\u003eWegmüller R et al. Zinc absorption by young adults from supplemental zinc citrate is comparable with that from zinc gluconate and higher than from zinc oxide. The Journal of Nutrition. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24259556\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\r\n\u003cli\u003eFairweather-Tait SJ et al. Selenium bioavailability: current knowledge and future research requirements. The American Journal of Clinical Nutrition. 2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20200264\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\r\n\u003cli\u003eHryb DJ et al. The effect of extracts of the roots of the stinging nettle (Urtica dioica) on the interaction of SHBG with its receptor on human prostatic membranes. Planta Medica. 1995. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7700987\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\r\n\u003cli\u003eRichelle M et al. A food-based formulation provides lycopene with the same bioavailability to humans as that from tomato paste. The Journal of Nutrition. 2002. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11880563\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\r\n\u003c\/ol\u003e\r\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424053018,"sku":"015-M1016","price":43.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1016_REV03_Listing_Image_1.png?v=1738258408"},{"product_id":"fabulously-female-vital-energy-wom","title":"Fabulously Female – Women's Energy \u0026 Stress Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eFabulously Female is a daily formula for women with 300 mg of KSM-66® ashwagandha extract, 500 mg of L-arginine and an 840 mg blend of horny goat weed, catuaba, muira puama, American ginseng, damiana and ginkgo leaf extract in every two-capsule serving. One bottle holds 60 vegetarian capsules, a 30-day supply. It supports a healthy response to everyday stress and steady energy, alongside herbs traditionally used for desire and vitality.†\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cp\u003eThis one is for women who are busy in every direction at once and want their energy, their stress response and their interest in the fun parts of life to keep up. It makes sense to start in your 30s and 40s, when work, kids, parents and workouts all want a piece of you, because the habits you build now are the ones you'll live on in your 70s and 80s. Aging isn't optional. Getting old is. And there's no caffeine on the label, so this isn't a jolt-and-crash product.\u003c\/p\u003e\n\n\u003ch2\u003eWhy people take Fabulously Female\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports a healthy response to everyday stress.\u003c\/strong\u003e Ashwagandha is an adaptogen, an herb that helps the body handle stress, and in placebo-controlled trials it has lowered cortisol, the body's main stress hormone.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports stamina and day-to-day energy.\u003c\/strong\u003e In a 12-week trial in healthy, active adults, KSM-66 at twice this amount raised a standard measure of aerobic fitness more than placebo did.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProvides L-arginine for nitric oxide.\u003c\/strong\u003e Your body uses L-arginine to make nitric oxide, a messenger that helps blood vessels widen and supports normal blood flow.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHerbs traditionally used for desire and vitality.\u003c\/strong\u003e Horny goat weed, catuaba, muira puama and damiana have long histories in traditional herbal practice as tonics for desire and vigor, and ginkgo leaf for healthy circulation.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eL-Arginine\u003c\/td\u003e\n\u003ctd\u003e500 mg\u003c\/td\u003e\n\u003ctd\u003e* (Daily Value not established)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWithania somnifera Extract (from KSM-66® Ashwagandha)\u003c\/td\u003e\n\u003ctd\u003e300 mg\u003c\/td\u003e\n\u003ctd\u003e* (Daily Value not established)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eProprietary Blend: Horny Goat Weed (Epimedium sagittatum, standardized to 10% icariin), Catuaba Bark (Erythroxylum catuaba), Muira Puama Bark 4:1 Extract (Ptychopetalum olacoides), American Ginseng (Panax quinquefolius), Damiana Leaf 4:1 Extract (Turnera diffusa), and Ginkgo biloba Leaf Extract (standardized to 24% ginkgoflavonglycosides and 6% terpene lactones)\u003c\/td\u003e\n\u003ctd\u003e840 mg\u003c\/td\u003e\n\u003ctd\u003e* (Daily Value not established)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size is 2 vegetarian capsules, with 30 servings per container. Other ingredients, exactly as printed: Vegetable cellulose (preservative-free, from capsule shell), cellulose, magnesium trisilicate, silica, and magnesium stearate. The label states: \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\n\u003ch2\u003eHow Fabulously Female works\u003c\/h2\u003e\n\n\u003ch3\u003eKSM-66® ashwagandha extract, 300 mg\u003c\/h3\u003e\n\u003cp\u003eAshwagandha (Withania somnifera) is a small shrub and a staple of Ayurveda, India's traditional system of medicine. Why KSM-66? It has its own published human trials. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26730141\/\"\u003ea 12-week KSM-66 trial in 49 healthy, active adults\u003c\/a\u003e, researchers describe it as a full-spectrum root extract standardized to 5% withanolides and made with a water-based process, without alcohol or chemical solvents. Our label doesn't print a withanolide percentage.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat the research shows.\u003c\/strong\u003e \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40746175\/\"\u003eA 2025 pooled analysis of randomized controlled ashwagandha trials\u003c\/a\u003e (488 people, all at 250 mg a day or more) found cortisol dropped by about 1.16 µg\/dL on average. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41824889\/\"\u003ea 60-day trial in 126 healthy adults with moderate perceived stress\u003c\/a\u003e, 300 mg once a day of a different, slow-release extract lowered stress scores more than placebo did; that study's lead authors work for supplement ingredient companies. And in the KSM-66 trial above, VO2 max, a standard measure of aerobic fitness, rose about three times as much as with placebo by week 12 (5.67 vs 1.86).†\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat it doesn't show.\u003c\/strong\u003e The pooled analysis found no significant change in how stressed people said they felt, even though cortisol came down, so the picture is real but mixed. The fitness trial used 600 mg a day, twice the amount here. You'll also see ashwagandha discussed for women's intimate wellness, and that research also used 600 mg a day, so we don't borrow it for this formula. Ashwagandha isn't a hormone, either: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41740946\/\"\u003ea 2026 analysis of 23 placebo-controlled trials\u003c\/a\u003e found it didn't change estradiol in women or men, or testosterone in women, though it nudged the thyroid hormone T4 up slightly. Nobody has run a trial on Fabulously Female itself.\u003c\/p\u003e\n\n\u003ch3\u003eL-Arginine, 500 mg\u003c\/h3\u003e\n\u003cp\u003eL-arginine is an amino acid you get from the protein in your diet, and your body makes some too. It's the raw material for nitric oxide, a signaling molecule that tells blood vessels to widen so more blood flows where it's needed (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32370176\/\"\u003ea systematic review and meta-analysis of arginine studies\u003c\/a\u003e).†\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat it doesn't show.\u003c\/strong\u003e Five hundred mg is a supporting role. In that review, the protocols linked to better aerobic performance used 1.5 to 2 grams a day for 4 to 7 weeks, and nearly all of the 394 people studied were men. Think of it as a building block, not a performance dose.\u003c\/p\u003e\n\n\u003ch3\u003eThe 840 mg herbal blend\u003c\/h3\u003e\n\u003cp\u003eThe label lists the six herbs as an 840 mg proprietary blend, so it gives the total, not each herb's amount.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHorny goat weed, standardized to 10% icariin.\u003c\/strong\u003e A leafy plant from traditional Chinese herbalism. Icariin is its signature compound, and \"standardized\" means each lot is made to that level.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCatuaba bark.\u003c\/strong\u003e A Brazilian tree bark used traditionally as a tonic for vitality.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMuira puama bark 4:1 extract.\u003c\/strong\u003e An Amazonian shrub traditionally used for desire and vigor. \"4:1\" means about 4 parts bark are concentrated into 1 part extract.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAmerican ginseng.\u003c\/strong\u003e The ginseng native to eastern North America, traditionally used for energy and stamina.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDamiana leaf 4:1 extract.\u003c\/strong\u003e A flowering shrub from Mexico and Central America, long used in traditional practice for desire and mood.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGinkgo biloba leaf extract.\u003c\/strong\u003e Traditionally used for healthy circulation, and standardized to 24% ginkgoflavonglycosides and 6% terpene lactones, its two main compound families.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWhat the research does and doesn't show.\u003c\/strong\u003e These herbs earn their place on tradition. Human research on them for women's desire is thin, mostly small studies of multi-ingredient products plus lab and animal work, and none of it tested this blend at these amounts. Better you hear that from us now.\u003c\/p\u003e\n\n\u003ch2\u003eHow to take Fabulously Female\u003c\/h2\u003e\n\u003cp\u003eLabel directions: \"Take two capsules per day as a dietary supplement.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThe label doesn't set a time of day or mention food, so both capsules together or one at breakfast and one at dinner both follow the directions.\u003c\/li\u003e\n\u003cli\u003eGive it two to three bottles. The individual ashwagandha trials above measured their results at 8 to 12 weeks.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eLabel warning: \"Not recommended while pregnant or lactating unless directed by healthcare practitioner.\"\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. That goes double for thyroid medication, since ashwagandha can nudge T4 up, and for blood thinners or blood pressure medication, since ginkgo and L-arginine both work around circulation.\u003c\/p\u003e\n\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, the KSM-66 and all six herbs included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Fabulously Female gets one.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility keeps the formulators, the makers and the testers under one roof, and the owners work in the building too (they've run the place since 2017). We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\n\u003ch3\u003eHow much ashwagandha is in Fabulously Female?\u003c\/h3\u003e\n\u003cp\u003eEach two-capsule serving has 300 mg of KSM-66® ashwagandha extract, plus 500 mg of L-arginine and an 840 mg herbal blend. A bottle holds 60 vegetarian capsules, or 30 servings.\u003c\/p\u003e\n\n\u003ch3\u003eWhen should I take it, and with food or without?\u003c\/h3\u003e\n\u003cp\u003eAny time of day works, because the label simply says two capsules per day and doesn't specify food. Take it the way that sits well with you.\u003c\/p\u003e\n\n\u003ch3\u003eHow long until I notice a difference?\u003c\/h3\u003e\n\u003cp\u003ePlan on 8 to 12 weeks of daily use. That's when the individual ashwagandha trials above measured their results.†\u003c\/p\u003e\n\n\u003ch3\u003eDoes Fabulously Female contain hormones?\u003c\/h3\u003e\n\u003cp\u003eNo, there are no hormones on the label. Ashwagandha is an herb, and in a 2026 analysis of 23 trials it didn't change estradiol or testosterone levels in women.\u003c\/p\u003e\n\n\u003ch3\u003eCan I take it with Women's Multi?\u003c\/h3\u003e\n\u003cp\u003eYes, as long as you count the ashwagandha. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-multi-cap-60ct\"\u003eWomen's Multi\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-50-plus-multivitamin\"\u003eWomen's 50+ Multivitamin\u003c\/a\u003e each have 300 mg of KSM-66 per serving, so either one plus Fabulously Female gives you 600 mg a day, the amount used in the KSM-66 fitness trial above. If you take medication, run it by your practitioner.\u003c\/p\u003e\n\n\u003ch3\u003eIs it safe with medication or during pregnancy?\u003c\/h3\u003e\n\u003cp\u003eCheck with your healthcare practitioner first. The label says it's not recommended while pregnant or lactating unless a practitioner directs it, and thyroid, blood-thinning and blood pressure medications are worth mentioning in that conversation.\u003c\/p\u003e\n\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-multi-cap-60ct\"\u003eWomen's Multi, a daily multivitamin with 300 mg of KSM-66\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-50-plus-multivitamin\"\u003eWomen's 50+ Multivitamin, the daily multi for women over 50\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/cortiresponse-stress-mood-support\"\u003eCortiResponse, our stress and mood formula with ashwagandha and L-theanine\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/maximum-male-vital-energy\"\u003eMaximum Male, the men's formula pairing KSM-66 with tribulus\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eAlbalawi AA. Dual impact of Ashwagandha: Significant cortisol reduction but no effects on perceived stress - A systematic review and meta-analysis. Nutr Health. 2025. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40746175\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eThanawala S et al. Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial. Medicine (Baltimore). 2026. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41824889\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eChoudhary B et al. Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults. Ayu. 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26730141\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eFornalik M et al. Hormonal Modulation with Withania somnifera: Systematic Review and Meta-Analysis of Randomized-controlled Trials. Planta Med. 2026. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41740946\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eViribay A et al. Effects of Arginine Supplementation on Athletic Performance Based on Energy Metabolism: A Systematic Review and Meta-Analysis. Nutrients. 2020. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32370176\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364424020250,"sku":"015-M1028","price":33.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1028_REV05_Necktag.png?v=1738258436"},{"product_id":"yourheart-nutrients-heart-health","title":"YourHeart Nutrients – Cardiovascular Function Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eYourHeart Nutrients is a daily heart formula with 500 mg of a beta-sitosterol plant sterol complex, 100 mg of CoQ10, 500 mg of Terminalia arjuna bark extract, 380 mg of L-citrulline malate and 210 mg of magnesium per 4-capsule serving, plus hawthorn, bromelain, potassium and vitamin C. A bottle holds 60 vegetarian capsules (15 servings). It helps maintain cholesterol levels already within the normal range and supports heart function.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eYour heart works every minute of your life, including the ones you spend reading product pages. YourHeart Nutrients is for people in their late 30s and 40s who already pay attention to food, movement and sleep, and for anyone over 50 who plans to keep going strong. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003cp\u003eThe label calls it a \"Single Bottle Solution\": plant sterols, CoQ10, circulation support and key minerals in one bottle instead of four. The candid trade-off is moderate amounts of each, not the largest dose of any one.\u003c\/p\u003e\n\u003ch2\u003eWhy people take YourHeart Nutrients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCholesterol levels already within the normal range.\u003c\/strong\u003e Plant sterols compete with cholesterol for absorption in your gut.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnergy for heart muscle.\u003c\/strong\u003e CoQ10 helps your mitochondria make ATP, the energy your heart cells run on.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHealthy circulation.\u003c\/strong\u003e L-citrulline is a building block for nitric oxide, the signal that lets blood vessel walls relax normally.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNormal heart rhythm.\u003c\/strong\u003e Magnesium helps carry calcium and potassium across cell membranes, part of normal heart rhythm.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTwo traditional heart botanicals.\u003c\/strong\u003e Arjuna bark and hawthorn berry have long traditional use for the heart and circulation.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin C (from Magnesium Ascorbate)\u003c\/td\u003e\n\u003ctd\u003e90 mg\u003c\/td\u003e\n\u003ctd\u003e100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium (from Magnesium Citrate and Ascorbate)\u003c\/td\u003e\n\u003ctd\u003e210 mg\u003c\/td\u003e\n\u003ctd\u003e50%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePotassium (from Potassium Citrate)\u003c\/td\u003e\n\u003ctd\u003e99 mg\u003c\/td\u003e\n\u003ctd\u003e2%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBeta-Sitosterol Phytosterol Complex (contains minimums of 300 mg beta-sitosterol, 175 mg campesterol, 105 mg stigmasterol, and 14 mg brassicasterol)\u003c\/td\u003e\n\u003ctd\u003e500 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cem\u003eTerminalia arjuna\u003c\/em\u003e 10:1 Bark Extract\u003c\/td\u003e\n\u003ctd\u003e500 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eL-Citrulline Malate\u003c\/td\u003e\n\u003ctd\u003e380 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHawthorn Berry Extract (\u003cem\u003eCrataegus laevigata\u003c\/em\u003e fruit)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBromelain 1200 GDU\/g\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCoenzyme Q10\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established. Serving size: 4 Capsules. Servings per container: 15, a 15-day supply at the label's 4 capsules a day. Other ingredients: Vegetarian capsules (hypromellose and water), cellulose, and silica. The label states: \"NO soy, salt, yeast, wheat, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow YourHeart Nutrients works\u003c\/h2\u003e\n\u003ch3\u003eBeta-sitosterol plant sterol complex, 500 mg\u003c\/h3\u003e\n\u003cp\u003ePlant sterols are the plant world's version of cholesterol. In your small intestine they crowd cholesterol out of the tiny fat droplets your body absorbs it from, so less gets absorbed and more leaves the body. They need cholesterol in your gut to compete with, from food and the bile released at meals, hence the label's \"preferably just prior to a meal.\"†\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19889819\/\"\u003ea controlled feeding study in 18 adults\u003c\/a\u003e, researchers added 0, 400 or 2,000 mg of plant sterols a day to a diet almost free of them, four weeks each. Compared with the near-zero period, at about 460 mg a day total the share of cholesterol absorbed fell about 10% and cholesterol excreted rose about 36%. Blood LDL cholesterol shifted significantly only at the 2,000 mg level. Two caveats: a serving here is 500 mg, close to that moderate level, and the authors note a healthy diet can supply that much on its own. Think of this as adding to your plate, not replacing it.\u003c\/p\u003e\n\u003ch3\u003eCoenzyme Q10, 100 mg\u003c\/h3\u003e\n\u003cp\u003eCoQ10 is a fat-soluble compound your body makes itself. It helps your mitochondria produce ATP and acts as an antioxidant in cell membranes. Heart muscle uses a lot of ATP, hence the CoQ10 and heart connection.†\u003c\/p\u003e\n\u003cp\u003eDoes it get in? In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18318910\/\"\u003ea 14-day trial in 41 trained and untrained adults\u003c\/a\u003e (average age 26), 100 mg of CoQ10 twice a day significantly raised blood CoQ10. Treadmill time to exhaustion trended longer but not significantly, and the daily dose was twice a serving here.\u003c\/p\u003e\n\u003ch3\u003eL-citrulline malate, 380 mg\u003c\/h3\u003e\n\u003cp\u003eL-citrulline is an amino acid (watermelon is the famous source). Your body converts it into L-arginine, which your blood vessel lining uses to make nitric oxide, the signal that tells vessel walls to relax as part of normal blood flow.† Why not just use arginine? Much of the arginine you swallow is broken down before it reaches your bloodstream.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17662090\/\"\u003ea placebo-controlled crossover study in 20 healthy volunteers\u003c\/a\u003e, oral citrulline raised blood arginine more effectively than arginine itself, and the top dose (3 g twice a day) increased markers of nitric oxide signaling. No dose improved flow-mediated dilation (how well an artery widens). At 380 mg, citrulline malate is a supporting player here.\u003c\/p\u003e\n\u003ch3\u003eTerminalia arjuna 10:1 bark extract, 500 mg\u003c\/h3\u003e\n\u003cp\u003eArjuna is a tree native to India whose bark has been used in Ayurveda as a heart tonic for centuries.† A 10:1 extract is concentrated about ten to one, so 500 mg reflects roughly 5 grams of bark, a source of flavonoids and tannins.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21170205\/\"\u003ean 8-week study of healthy young adults\u003c\/a\u003e, the 10 people who took 500 mg a day of arjuna bark extract showed an increase in VO2 max, a standard measure of aerobic fitness. Same daily amount as here, but with 10 people per group it's an early signal, not settled science.\u003c\/p\u003e\n\u003ch3\u003eHawthorn berry extract, 100 mg\u003c\/h3\u003e\n\u003cp\u003eHawthorn (\u003cem\u003eCrataegus laevigata\u003c\/em\u003e) is a European shrub whose berries are a traditional herbal choice for the heart and circulation.† We found no good trials of hawthorn fruit in healthy adults at this amount, so we won't claim one. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29672935\/\"\u003ea crossover trial in 20 healthy adults\u003c\/a\u003e, a single 160 mg dose didn't change ECG readings versus placebo, with no significant side effects: a safety note, not a benefit.\u003c\/p\u003e\n\u003ch3\u003eMagnesium, vitamin C and potassium\u003c\/h3\u003e\n\u003cp\u003eMagnesium (210 mg, 50% DV) helps carry calcium and potassium across cell membranes for nerve signals, muscle contraction and normal heart rhythm, per \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Magnesium-HealthProfessional\/\"\u003ethe NIH magnesium fact sheet\u003c\/a\u003e, which also lists citrate among the forms absorbed more completely than magnesium oxide.† Vitamin C (90 mg, 100% DV) comes with the magnesium ascorbate, and your body needs it to make collagen, per \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminC-HealthProfessional\/\"\u003ethe NIH vitamin C fact sheet\u003c\/a\u003e.† Potassium is 99 mg (2% DV), a typical amount: \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Potassium-HealthProfessional\/\"\u003ethe NIH potassium fact sheet\u003c\/a\u003e explains many supplement makers cap it there because of FDA concerns about higher-dose potassium drug products.\u003c\/p\u003e\n\u003ch3\u003eBromelain 1200 GDU\/g, 100 mg\u003c\/h3\u003e\n\u003cp\u003eBromelain is a group of protein-digesting enzymes from the pineapple plant, rated by activity (gelatin digesting units per gram). It plays a supporting role, and we make no separate claim for it.\u003c\/p\u003e\n\u003ch3\u003eWhat the research does and doesn't show\u003c\/h3\u003e\n\u003cp\u003eWe know of no published trial of this exact formula. The studies above tested single ingredients over hours to weeks, several at larger doses. They show how each ingredient works, not a promised change by a specific date.\u003c\/p\u003e\n\u003ch2\u003eHow to take YourHeart Nutrients\u003c\/h2\u003e\n\u003cp\u003eDirections from the label: \"Take two capsules twice daily (total of 4 per day), preferably just prior to a meal.\"\u003c\/p\u003e\n\u003cp\u003eSplitting the serving across two meals fits how the sterols work, and CoQ10 is fat-soluble. Bromelain comes from pineapple, worth knowing if pineapple doesn't agree with you.\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, from the plant sterols to the arjuna bark, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Each one records what that lot was tested for and the results.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility sits right in it. The people who formulate YourHeart Nutrients, make it and test it all work under one roof, and the owners work in the building too (owner-run since 2017). We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many capsules of YourHeart Nutrients do I take a day?\u003c\/h3\u003e\n\u003cp\u003eFour: the label says two capsules twice daily, preferably just before a meal. A 60-capsule bottle is 15 servings, so it lasts 15 days.\u003c\/p\u003e\n\u003ch3\u003eHow long before I notice anything?\u003c\/h3\u003e\n\u003cp\u003eThere's no set timeline, and you probably won't \"feel\" plant sterols at all. In the studies above, cholesterol absorption was measured after four weeks and blood CoQ10 rose within two. Your practitioner can track your numbers at checkups.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with your other CoQ10 or magnesium products?\u003c\/h3\u003e\n\u003cp\u003eYes, but add up the totals. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/coq10-alpha-lipoic-acid\"\u003eCoQ10 Plus Alpha Lipoic Acid\u003c\/a\u003e has 100 mg of CoQ10 per capsule, and the \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-50-plus-multivitamin\"\u003eMen's 50+ Multivitamin\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-50-plus-multivitamin\"\u003eWomen's 50+ Multivitamin\u003c\/a\u003e each have 100 mg per serving, so any one of them plus this formula is 200 mg a day. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium\u003c\/a\u003e has 200 mg of magnesium per capsule; with the 210 mg here that's 410 mg, above the 350 mg upper limit for supplemental magnesium in adults listed in the NIH magnesium fact sheet, so ask your practitioner first.\u003c\/p\u003e\n\u003ch3\u003eDoes it contain soy, gluten or dairy?\u003c\/h3\u003e\n\u003cp\u003eNo. The label states: \"NO soy, salt, yeast, wheat, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" The capsules are vegetarian.\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner before you start, especially if you take a blood thinner, blood pressure medication, or a medication that affects potassium. Bring the bottle so they can read the full label.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/single-bottle-solution-what-is-it-and-why-do-we-put-it-on-our-premium-bottles\"\u003eWhat \"Single Bottle Solution\" on our labels means\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/quercetin-zinc-quercetin-nettle-hr\"\u003eYourHeart Nutrients bundled with Quercetin Zinc and Quercetin Nettle+\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eRacette SB et al. Dose effects of dietary phytosterols on cholesterol metabolism: a controlled feeding study. Am J Clin Nutr. 2009. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19889819\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCooke M et al. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18318910\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSchwedhelm E et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17662090\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSandhu JS et al. Effects of Withania somnifera (Ashwagandha) and Terminalia arjuna (Arjuna) on physical performance and cardiorespiratory endurance in healthy young adults. Int J Ayurveda Res. 2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21170205\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eTrexler SE et al. Electrocardiographic effects of hawthorn (Crataegus oxyacantha) in healthy volunteers: A randomized controlled trial. Phytother Res. 2018. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29672935\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364423987482,"sku":"015-M7110","price":27.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M7110_REV01_Necktag.png?v=1738258475"},{"product_id":"quercetin-zinc","title":"Quercetin Zinc – Immune Support with Vitamin C and D3 | 120 or 300 Capsules","description":"\u003cp\u003e\u003cstrong\u003eQuercetin Zinc is a daily immune support supplement with 530 mg of quercetin, 7.5 mg of zinc (from zinc ascorbate), 120 mg of vitamin C and 25 mcg of vitamin D3 in every 2-capsule serving, plus 50 mg each of bromelain and stinging nettle root. It comes in bottles of 120 or 300 vegetarian capsules and supports normal immune function.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eQuercetin Zinc is for adults who want everyday immune support without lining up four bottles on the counter. Zinc, vitamin C and vitamin D3 are three nutrients your immune cells lean on, and quercetin is the plant flavonoid people pair with them.† Two capsules with a meal and you're done.\u003c\/p\u003e\n\u003cp\u003eYou don't need to wait until your 60s to care about this. If you're in your 30s or 40s and already paying attention to sleep, training and what's on your plate, this is the easy part of the routine. Small, steady habits now are how you add life to your years later.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Quercetin Zinc\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports normal immune function with zinc, vitamin C and vitamin D3, three nutrients immune cells depend on.†\u003c\/li\u003e\n\u003cli\u003eDelivers 530 mg of quercetin, a plant flavonoid studied for its antioxidant activity.†\u003c\/li\u003e\n\u003cli\u003eSupports the body's normal antioxidant defenses with zinc and vitamin C.†\u003c\/li\u003e\n\u003cli\u003eCovers 133% of the Daily Value for vitamin C, 125% for vitamin D and 68% for zinc in one daily serving, to help fill gaps in your diet.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin C\u003c\/td\u003e\n\u003ctd\u003e120 mg\u003c\/td\u003e\n\u003ctd\u003e133%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin D3 (Cholecalciferol)\u003c\/td\u003e\n\u003ctd\u003e25 mcg\u003c\/td\u003e\n\u003ctd\u003e125%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eZinc (from Zinc Ascorbate)\u003c\/td\u003e\n\u003ctd\u003e7.5 mg\u003c\/td\u003e\n\u003ctd\u003e68%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eQuercetin\u003c\/td\u003e\n\u003ctd\u003e530 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBromelain (from Pineapple)\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStinging Nettle Root\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 2 capsules. Servings per container: 60 in the 120-count bottle and 150 in the 300-count bottle, as printed on each bottle's Supplement Facts panel. Other ingredients: Cellulose (from capsule shell), Calcium Phosphate, Magnesium Stearate, and Silicon Dioxide. The label states: \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" It also states: \"This product does not contain genetically modified materials.\"\u003c\/p\u003e\n\u003ch2\u003eHow Quercetin Zinc works\u003c\/h2\u003e\n\u003ch3\u003eQuercetin: 530 mg per serving\u003c\/h3\u003e\n\u003cp\u003eQuercetin is a flavonoid, a plant compound found in small amounts in fruits and vegetables. Food gives you a little. A supplement gives you a lot more than a normal diet does (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29127724\/\"\u003ea safety review of quercetin supplements\u003c\/a\u003e makes the same point): 530 mg per serving here, or 265 mg per capsule. In lab tests quercetin behaves as an antioxidant, which is why people take it for antioxidant support.†\u003c\/p\u003e\n\u003cp\u003eHere's what the human research shows. Quercetin does get absorbed. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18716159\/\"\u003ea 2-week randomized trial in 35 healthy adults\u003c\/a\u003e, taking 50 to 150 mg a day raised blood quercetin levels in step with the dose (up 178% to 570% from baseline), with big differences from person to person. What it doesn't show: the same trial found no change in blood antioxidant capacity or inflammation markers. So, straight talk: quercetin reaches your bloodstream, and what that does for healthy adults is still being worked out. Our 530 mg is well above the doses in that trial, so its numbers don't map one-to-one.\u003c\/p\u003e\n\u003ch3\u003eZinc: 7.5 mg from zinc ascorbate\u003c\/h3\u003e\n\u003cp\u003eZinc is an essential mineral, so it has to come from food or a supplement. Immune cells use zinc ions to pass signals inside the cell, on both the fast-acting innate side of the immune system and the slower, targeted adaptive side, and zinc has long been documented as part of the body's normal antioxidant defenses (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29186856\/\"\u003ea review of zinc's role in immune function\u003c\/a\u003e).†\u003c\/p\u003e\n\u003cp\u003eThe zinc here is zinc ascorbate, which is zinc bound to ascorbic acid (vitamin C). The amount is moderate: 7.5 mg is 68% of the Daily Value, a top-up to the zinc you already eat, not a megadose. Even at the label's maximum of 4 capsules a day, the capsules give you 15 mg of zinc.\u003c\/p\u003e\n\u003ch3\u003eWhy quercetin and zinc together\u003c\/h3\u003e\n\u003cp\u003eZinc normally moves into cells through dedicated transporter proteins. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25050823\/\"\u003ea lab study using a mouse liver cell line and artificial membranes\u003c\/a\u003e, quercetin carried zinc across the membrane by itself, acting as what chemists call a zinc ionophore. That's a cell-and-test-tube finding, not a human trial: it's why the pairing is interesting, not proof it works that way in your body.\u003c\/p\u003e\n\u003ch3\u003eVitamin C: 120 mg\u003c\/h3\u003e\n\u003cp\u003eYour body can't make vitamin C, so it has to come from food or supplements. Vitamin C is an antioxidant, and immune cells called neutrophils collect it and hold onto it. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29099763\/\"\u003eA review of vitamin C and immune function\u003c\/a\u003e describes how it supports the normal work of both the innate and adaptive immune system.† The 120 mg here is 133% of the Daily Value.\u003c\/p\u003e\n\u003ch3\u003eVitamin D3: 25 mcg\u003c\/h3\u003e\n\u003cp\u003eThis is vitamin D3, cholecalciferol, the same form your skin makes from sunlight. Most people know vitamin D for bones, but B cells, T cells and antigen-presenting cells all carry vitamin D receptors and can make the active form of vitamin D right where they work. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21527855\/\"\u003eA review of vitamin D and the immune system\u003c\/a\u003e explains how that lets vitamin D help regulate normal innate and adaptive immune responses.† The 25 mcg here is 125% of the Daily Value.\u003c\/p\u003e\n\u003ch3\u003eBromelain and stinging nettle root: 50 mg each\u003c\/h3\u003e\n\u003cp\u003eBromelain is a group of protein-digesting enzymes from pineapple. Stinging nettle root comes from the same plant you've probably brushed against on a hike and regretted. Both are supporting players at 50 mg each, and we won't dress them up: we haven't found good human research on either one at these amounts for immune support, so we don't make claims for them.\u003c\/p\u003e\n\u003ch2\u003eHow to take Quercetin Zinc\u003c\/h2\u003e\n\u003cp\u003eTake two capsules daily with a meal, or as directed by your health care provider. Do not exceed 4 capsules daily.\u003c\/p\u003e\n\u003cp\u003eA practical tip: tie it to the meal you never skip, so the habit sticks. If you take other products with zinc, vitamin D or quercetin, add up the totals (see the FAQ below).\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eChecked off the shelf.\u003c\/strong\u003e When an outside lab bought our Quercetin Zinc off the shelf in 2022, it tested at 104% of its label claim.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Quercetin Zinc has its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility there puts formulators, makers and testers under one roof. The owners work in the building too, and have since 2017. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much quercetin is in Quercetin Zinc?\u003c\/h3\u003e\n\u003cp\u003eEach 2-capsule serving has 530 mg of quercetin, which works out to 265 mg per capsule. The same serving also gives you 7.5 mg of zinc, 120 mg of vitamin C, 25 mcg of vitamin D3, and 50 mg each of bromelain and stinging nettle root.\u003c\/p\u003e\n\u003ch3\u003eWhen should I take it, and does it need food?\u003c\/h3\u003e\n\u003cp\u003eTake it with a meal, at any time of day. The label doesn't name a time, so pick the meal you're most consistent with.\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eMost people won't feel it day to day, and that's normal. Zinc, vitamin C and vitamin D do their work in the background of normal immune function, so the goal is steady daily intake, not a buzz.† In the trial above, blood quercetin levels rose within 2 weeks of daily use, but that's a lab number, not a feeling.\u003c\/p\u003e\n\u003ch3\u003eHow long does a bottle last?\u003c\/h3\u003e\n\u003cp\u003eAt two capsules a day, the 120-capsule bottle lasts 60 days and the 300-capsule bottle lasts 150 days, about five months.\u003c\/p\u003e\n\u003ch3\u003eCan I take Quercetin Zinc with other Mt. Angel Vitamins products?\u003c\/h3\u003e\n\u003cp\u003eYes, but add up the overlap first. Our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/advanced-zinc-citrate-50mg\"\u003eZinc 50 mg Citrate Chelate\u003c\/a\u003e plus a serving of Quercetin Zinc comes to 57.5 mg of zinc a day before food, more than five times the Daily Value (the two labels list 454% and 68%), so check with your practitioner before doubling up. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/natural-allergy-solution-quercetin\"\u003eQuercetin Nettle+\u003c\/a\u003e adds 1,000 mg of quercetin per 3-tablet serving. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29127724\/\"\u003eA safety review of quercetin supplements\u003c\/a\u003e found side effects in human studies were rare and mild, but long-term data (beyond 12 weeks) at 1,000 mg a day or more aren't available yet, so run a months-long stack by your practitioner.\u003c\/p\u003e\n\u003ch3\u003eIs it OK to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first. The same safety review notes that quercetin can change how much of certain drugs reaches your bloodstream, so your practitioner or pharmacist should see your full list before you start.\u003c\/p\u003e\n\u003ch3\u003eIs Quercetin Zinc vegetarian?\u003c\/h3\u003e\n\u003cp\u003eThe capsules are. The label calls them vegetarian capsules, and the capsule shell is cellulose. The label doesn't make a vegan claim.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/our-approach-to-raw-material-sourcing-and-testing\"\u003eHow we source and test raw materials\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/natural-allergy-solution-quercetin\"\u003eQuercetin Nettle+, a higher-quercetin tablet\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eEgert S et al. Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans. J Nutr. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18716159\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWessels I et al. Zinc as a Gatekeeper of Immune Function. Nutrients. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29186856\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDabbagh-Bazarbachi H et al. Zinc ionophore activity of quercetin and epigallocatechin-gallate: from Hepa 1-6 cells to a liposome model. J Agric Food Chem. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25050823\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCarr AC, Maggini S. Vitamin C and Immune Function. Nutrients. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29099763\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAranow C. Vitamin D and the immune system. J Investig Med. 2011. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21527855\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAndres S et al. Safety Aspects of the Use of Quercetin as a Dietary Supplement. Mol Nutr Food Res. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29127724\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"120","offer_id":44364427690266,"sku":"010-A1028-120","price":35.99,"currency_code":"USD","in_stock":true},{"title":"300","offer_id":44398263370010,"sku":"010-A1028-300","price":71.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A1028_Necktag_Transparent.png?v=1738588344"},{"product_id":"good-energy-stamina-support","title":"Good Energy+ – Energy \u0026 Endurance Support | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eGood Energy+ is a caffeinated energy and endurance supplement in 60 vegetarian capsules, 30 servings per bottle. Each 2-capsule serving delivers 400 mg Rhodiola rosea root extract (1% salidrosides), 100 mg Panax ginseng root extract (4% ginsenosides) and 100 mg caffeine (42 mg from yerba mate, 58 mg added), plus a 1,002 mg proprietary blend, to support energy, alertness and endurance.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGood Energy+ is for the days that ask a lot: the early workout, the packed calendar, the 2 p.m. slump. It fits people in their 30s and 40s building habits now so they can keep doing what they love in their 70s and 80s, and people past 50 with zero plans to slow down. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003cp\u003eIt isn't a stand-in for sleep, food or water. It's measured caffeine plus Rhodiola and ginseng, with the key amounts on the panel.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Good Energy+\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEndurance.\u003c\/strong\u003e Rhodiola rosea supports physical endurance during exercise, with the most consistent research on single doses taken before a workout.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlertness.\u003c\/strong\u003e 100 mg of caffeine per serving supports alertness, attention and reaction time.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMental performance.\u003c\/strong\u003e Caffeine supports mental performance on demanding days, with Panax ginseng playing a supporting part.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnergy you can measure.\u003c\/strong\u003e Supports energy for your workday or workout, with the exact caffeine amount and its sources printed on the label.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cem\u003eRhodiola rosea\u003c\/em\u003e Root Standardized Extract (standardized to 1% salidrosides)\u003c\/td\u003e\n\u003ctd\u003e400 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cem\u003ePanax ginseng\u003c\/em\u003e Root Standardized Extract (standardized to 4% ginsenosides by HPLC)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCaffeine (42mg from Yerba Matte, 58mg from added caffeine)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eProprietary Blend (Contains: Yerba matte Leaf Standardized Extract (Ilex paraguariensis), Sea Buckthorn Berry Extract (Hippophae rhamnoides), Goji Fruit Extract (Lycium barbarum), Bromelain (1200 GDU\/g), Royal Jelly Standardized Concentrate (contains 4.0% 10-hydroxy-2-decenoic acid), Eleutherococcus senticosus Root 50:1 Extract, and Bioperine®.)\u003c\/td\u003e\n\u003ctd\u003e1,002 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eServing size:\u003c\/strong\u003e 2 Vegetarian Capsules. \u003cstrong\u003eServings per container:\u003c\/strong\u003e 30. \u003cstrong\u003eOther ingredients:\u003c\/strong\u003e Vegetable cellulose (preservative-free, from capsule shell), magnesium stearate, and silica. The front of the bottle states \"CONTAINS 100MG CAFFEINE\", and the panel notes \"Bioperine® Licensed Under US Patent Numbers 5,536,161; 5,744,382; and 6,054,585\".\u003c\/p\u003e\n\u003ch2\u003eHow Good Energy+ works\u003c\/h2\u003e\n\u003ch3\u003eRhodiola rosea: 400 mg, standardized to 1% salidrosides\u003c\/h3\u003e\n\u003cp\u003eRhodiola is a hardy plant from high, harsh climates in Europe and Asia. Our root extract is standardized to 1% salidrosides, one of the marker compounds researchers measure in Rhodiola, so every lot has to hit the same level instead of being \"some amount of ground root.\"\u003c\/p\u003e\n\u003cp\u003eThe research is most consistent for endurance. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15256690\/\"\u003ea double-blind trial in 24 young, healthy volunteers\u003c\/a\u003e, a single 200 mg dose taken an hour before testing increased time to exhaustion from 16.8 to 17.2 minutes on average. A small gain, and four weeks of daily use didn't add to it. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37495266\/\"\u003eA 2023 systematic review of 13 randomized trials in 263 healthy adults\u003c\/a\u003e found single pre-exercise doses had a positive effect on endurance and on how hard exercise felt, while longer-term use helped short, intense (anaerobic) efforts but not endurance.† Most studies had an unclear or high risk of bias, so more high-quality trials are needed. Good Energy+ provides 400 mg, but extracts and doses in these trials varied, so results don't transfer one-for-one.\u003c\/p\u003e\n\u003ch3\u003ePanax ginseng: 100 mg, standardized to 4% ginsenosides\u003c\/h3\u003e\n\u003cp\u003ePanax ginseng is a root with a long history of traditional use in East Asia. Its main active compounds are ginsenosides, and ours are measured by HPLC, a lab method that separates and quantifies the individual compounds.\u003c\/p\u003e\n\u003cp\u003eThe human research is real but mixed. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20737519\/\"\u003ea crossover trial in 30 healthy young adults\u003c\/a\u003e, 400 mg of a standardized extract improved mental arithmetic and ratings of calmness, while 200 mg slowed the usual drop in mood but also slowed responses on the math task. A week of daily use added nothing beyond the first dose.† At 100 mg, ginseng is a supporting player here, not the headliner.\u003c\/p\u003e\n\u003ch3\u003eCaffeine: 100 mg, with the sources spelled out\u003c\/h3\u003e\n\u003cp\u003eThrough the day, a compound called adenosine builds up in the brain and nudges you toward feeling tired. Caffeine blocks adenosine's receptors, so that signal gets muffled for a while. Each serving has 100 mg: 42 mg from yerba mate leaf extract and 58 mg of added caffeine.\u003c\/p\u003e\n\u003cp\u003eYou don't need a huge dose to notice it. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3114783\/\"\u003ea controlled study of low caffeine doses in 20 healthy men\u003c\/a\u003e, single doses from 32 to 256 mg each improved auditory vigilance and visual reaction time, with no adverse behavioral effects noted.† \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25355191\/\"\u003eA review of low-dose caffeine and exercise\u003c\/a\u003e found that about 200 mg or less can support vigilance, alertness and mood during and after exercise with few if any side effects, though responses vary.† A \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28438661\/\"\u003elarge systematic review of caffeine safety\u003c\/a\u003e concluded that up to 400 mg a day isn't associated with overt adverse effects in healthy adults.\u003c\/p\u003e\n\u003ch3\u003eThe 1,002 mg proprietary blend\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eYerba mate leaf extract\u003c\/strong\u003e (\u003cem\u003eIlex paraguariensis\u003c\/em\u003e): the South American leaf brewed as mate tea, and the source of 42 mg of the caffeine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSea buckthorn berry\u003c\/strong\u003e and \u003cstrong\u003egoji fruit\u003c\/strong\u003e extracts: two berries from Europe and Asia.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBromelain (1200 GDU\/g)\u003c\/strong\u003e: protein-digesting enzymes from pineapple. GDU measures enzyme activity, not just weight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoyal jelly concentrate\u003c\/strong\u003e: made by worker bees to feed developing bees and the queen, standardized to 4.0% 10-HDA, a fatty acid characteristic of royal jelly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEleutherococcus senticosus root 50:1 extract\u003c\/strong\u003e (eleuthero): roughly 50 parts raw root concentrated into each part of extract.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBioperine®\u003c\/strong\u003e: a black pepper extract standardized for piperine.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTo be candid: the label lists the blend as one total, so we don't make specific claims for individual blend ingredients. The three ingredients with printed amounts are the ones you can check.\u003c\/p\u003e\n\u003ch2\u003eHow to take Good Energy+\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDirections (from the label):\u003c\/strong\u003e \"Take two capsules prior to a meal, in the morning or afternoon, as a dietary supplement.\"\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCount your caffeine.\u003c\/strong\u003e Add the 100 mg per serving to your coffee, tea, soda, pre-workout and energy drinks.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep it to the morning or afternoon,\u003c\/strong\u003e as the label says. Late-day caffeine can get in the way of a good night's sleep.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBefore a workout:\u003c\/strong\u003e the most promising Rhodiola research used a single dose about an hour before exercise.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIf you react to bee products (royal jelly) or caffeine makes you jittery, ask your practitioner first. Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. Because it contains caffeine, store it out of reach of children.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cp\u003eWe've been making supplements in Oregon since 1974. After 52 years, we'd still rather show you the work than ask for your trust.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test. We test every incoming ingredient lot, from the Rhodiola to the yerba mate, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e That includes Good Energy+.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e That's a farm town of about 3,500 people in the Willamette Valley. Good Energy+ is made in our UL-certified cGMP facility, where the formulators, makers and testers work under one roof and the owners work in the building too. Owner-run since 2017, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much caffeine is in Good Energy+?\u003c\/h3\u003e\n\u003cp\u003eEach 2-capsule serving has 100 mg of caffeine: 42 mg from yerba mate leaf extract and 58 mg added. That's a quarter of the 400 mg a day the caffeine safety review above found isn't associated with overt adverse effects in healthy adults, so count it with your other sources.\u003c\/p\u003e\n\u003ch3\u003eWhen should I take it, and with food?\u003c\/h3\u003e\n\u003cp\u003eTake two capsules prior to a meal, in the morning or afternoon, as the label directs. Before breakfast or lunch works, and it keeps the caffeine out of your evening.\u003c\/p\u003e\n\u003ch3\u003eHow soon will I notice it?\u003c\/h3\u003e\n\u003cp\u003eThe caffeine works the day you take it. The Rhodiola endurance trial above tested one hour after a single dose, and four weeks of daily use added nothing more, so judge it day by day.†\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Adrenal Support or a B vitamin?\u003c\/h3\u003e\n\u003cp\u003eThey can be used together, but know the overlap. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/adrenal-support-60-vegetarian\"\u003eAdrenal Support\u003c\/a\u003e also contains Rhodiola root extract (1% salidrosides) and Eleutherococcus senticosus root 50:1 extract, so you'd get more of both. For energy support without more caffeine, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/b12-sublingual-essential-trio\"\u003eB-12 Essential Trio\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/b-good-com-vitamin-b-complex\"\u003eB-Complex\u003c\/a\u003e are B vitamin formulas (neither label lists caffeine) that support normal energy metabolism.†\u003c\/p\u003e\n\u003ch3\u003eDoes Good Energy+ support healthy blood sugar?\u003c\/h3\u003e\n\u003cp\u003eThat isn't what it's labeled for. Good Energy+ is formulated for energy and endurance, and that's the job we stand behind. If supporting healthy blood sugar levels already within the normal range is your main goal, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/blood-sugar-support-60ct-caps\"\u003eBlood Sugar Support\u003c\/a\u003e is the formula we make for that.†\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner before you start. Bring the bottle so they can check the caffeine, botanicals and royal jelly against what you take.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/our-approach-to-formulation\"\u003eHow our formulator decides which ingredients belong together\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/energy-focus-stack-adrenal-b12\"\u003eEnergy \u0026amp; Focus Stack: Adrenal Support, B-12 Essential Trio and B-Complex\u003c\/a\u003e (none of the three labels lists caffeine)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eDe Bock K et al. Acute Rhodiola rosea intake can improve endurance exercise performance. Int J Sport Nutr Exerc Metab. 2004. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15256690\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSanz-Barrio PM et al. Rhodiola rosea supplementation on sports performance: A systematic review of randomized controlled trials. Phytother Res. 2023. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37495266\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eReay JL et al. Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults. Hum Psychopharmacol. 2010. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20737519\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eLieberman HR et al. The effects of low doses of caffeine on human performance and mood. Psychopharmacology (Berl). 1987. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3114783\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSpriet LL. Exercise and sport performance with low doses of caffeine. Sports Med. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25355191\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWikoff D et al. Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Food Chem Toxicol. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28438661\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":44364422283546,"sku":"010-A1029","price":31.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A3008_Bottle_Mockup_Center.png?v=1738258710"},{"product_id":"inflameze-ultra-caps-50ct","title":"Inflameze Ultra – Curcumin + ParActin Joint Comfort | 50 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eInflameze Ultra is a joint comfort supplement with 500 mg of turmeric root extract (Curcumin C3 Complex®), 300 mg of organic ParActin® andrographis leaf extract, 250 mg of organic ginger root and 5 mg of BioPerine® black pepper extract in every 2-capsule serving. Each bottle holds 50 vegetarian capsules, or 25 servings. It supports joint comfort, and its curcumin has been studied for muscle comfort after exercise.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eInflameze Ultra is for people whose plans still involve stairs, trails and heavy bags of potting soil: the 40-year-old back in the gym, the 55-year-old who would rather garden than sit. It keeps the formula short (four active ingredients) and pairs 500 mg of turmeric extract with the black pepper extract that helps curcumin absorb.†\u003c\/p\u003e\n\u003cp\u003eAging isn't optional. Getting old is. Your joints carry you through every decade, and the habits that keep them moving (strength work, walking, sleep, decent food) pay off most when you start in your 30s and 40s. Inflameze Ultra is one small, steady part of that routine, not a replacement for it.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Inflameze Ultra\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports joint comfort, the claim printed on the side of every bottle.†\u003c\/li\u003e\n\u003cli\u003eBrings 500 mg of Curcumin C3 Complex turmeric extract per serving, and curcumin has been studied for muscle comfort after hard exercise (the evidence is mixed).†\u003c\/li\u003e\n\u003cli\u003ePairs that curcumin with BioPerine black pepper extract, which helps the body absorb curcumin.†\u003c\/li\u003e\n\u003cli\u003eRounds out the joint comfort formula with two organic botanicals: 300 mg of ParActin andrographis leaf extract and 250 mg of ginger root.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTurmeric Root Extract (Curcumin C³ Complex®)\u003c\/td\u003e\n\u003ctd\u003e500 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrganic ParActin® \u003cem\u003eAndrographis paniculata\u003c\/em\u003e Leaf Extract (Bioactive 14-Neo-Andro Compound)\u003c\/td\u003e\n\u003ctd\u003e300 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrganic Ginger Root (\u003cem\u003eZingiber officinale\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e250 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBioPerine® (Black Pepper Extract)\u003c\/td\u003e\n\u003ctd\u003e5 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value Not Established. Serving size: 2 capsules. Servings per container: 25. The bottle holds 50 vegetarian capsules, and the front label carries a crossed-out gluten icon. For the other ingredients and label statements, see the panel on your bottle.\u003c\/p\u003e\n\u003ch2\u003eHow Inflameze Ultra works\u003c\/h2\u003e\n\u003cp\u003eStraight talk first: nobody has run a clinical trial on Inflameze Ultra as a finished formula. The research below is on single ingredients, usually in other forms and amounts.\u003c\/p\u003e\n\u003ch3\u003eCurcumin C3 Complex: 500 mg of turmeric root extract\u003c\/h3\u003e\n\u003cp\u003eTurmeric is the golden root behind curry's color, and curcuminoids are the compounds that make it gold. Curcumin C3 Complex is a branded turmeric root extract built around three curcuminoids: curcumin, demethoxycurcumin and bisdemethoxycurcumin. One 2-capsule serving gives you 500 mg of it.\u003c\/p\u003e\n\u003cp\u003eWhat the research shows: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37460208\/\"\u003ean umbrella review of meta-analyses of randomized trials\u003c\/a\u003e rated curcumin's effect on muscle soreness after muscle-damaging exercise as moderate-certainty evidence.† What it doesn't: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37408367\/\"\u003ea 2023 systematic review and meta-analysis that included 16 studies\u003c\/a\u003e found no statistically significant effect on post-exercise soreness, muscle damage markers or inflammation markers at any time point it measured. Both reviews pooled many curcumin forms and doses, so read them as background, not a promise for this capsule.\u003c\/p\u003e\n\u003ch3\u003eBioPerine: 5 mg of black pepper extract\u003c\/h3\u003e\n\u003cp\u003eCurcumin doesn't stick around: the gut wall and liver tag it for removal almost as fast as it arrives. Piperine, the compound that gives black pepper its bite, slows one of those tagging steps (a process called glucuronidation). In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9619120\/\"\u003ea 1998 study in healthy human volunteers\u003c\/a\u003e, 2 grams of plain curcumin alone left blood levels undetectable or very low, while adding 20 mg of piperine raised curcumin's bioavailability by 2,000%.\u003c\/p\u003e\n\u003cp\u003eInflameze Ultra keeps that same 1-to-100 ratio (5 mg to 500 mg) at a quarter of the amounts. The study used plain curcumin, not Curcumin C3 Complex, and we haven't found one at our exact amounts, so read the 2,000% as proof of concept, not a number for this bottle.\u003c\/p\u003e\n\u003ch3\u003eOrganic ParActin andrographis: 300 mg\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eAndrographis paniculata\u003c\/em\u003e is a leafy herb. ParActin is a trademarked extract of its leaf, and the one in Inflameze Ultra is organic, per the label. The label names its bioactive marker the \"14-Neo-Andro Compound.\" Researchers describe four major active compounds in the plant, all diterpenoids, including andrographolide, neoandrographolide and 14-deoxyandrographolide.\u003c\/p\u003e\n\u003cp\u003eDo they get into your body? In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27702690\/\"\u003ea study of 20 healthy adults\u003c\/a\u003e who took andrographis capsules three times a day for three days, all four of the plant's main diterpenoids showed up in the blood, and dose for dose, exposure to neoandrographolide and 14-deoxyandrographolide ran about 1.5 and 1.6 times that of andrographolide. That study used a different andrographis product and shows absorption, not how your knees feel. We haven't found a ParActin trial in healthy adults we'd stand behind, so we don't quote results here.\u003c\/p\u003e\n\u003ch3\u003eOrganic ginger root: 250 mg\u003c\/h3\u003e\n\u003cp\u003eThis is the same knobby root in your spice drawer, and the label lists it as ginger root, not an extract. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26200194\/\"\u003eA systematic review of randomized trials in exercise and sport\u003c\/a\u003e concluded that roughly 2 grams of ginger a day may modestly ease muscle soreness from hard eccentric lifting and long runs, especially when taken for at least 5 days, with no clear effect on things like oxygen use or muscle force.† In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30299178\/\"\u003ea randomized, double-blind trial in 32 experienced recreational runners\u003c\/a\u003e, 1.425 grams a day of ginger root for 5 days likely blunted the rise in soreness while jogging after a 40-minute downhill run, but likely made no meaningful difference to 1.5-mile run times.\u003c\/p\u003e\n\u003cp\u003eHonest math: 250 mg is an eighth of 2 grams. In Inflameze Ultra, ginger is a supporting player; the formula is built around the curcumin and the andrographis.\u003c\/p\u003e\n\u003ch2\u003eHow to take Inflameze Ultra\u003c\/h2\u003e\n\u003cp\u003eOne serving is 2 capsules, according to the Supplement Facts panel, and the bottle holds 25 servings. Follow the directions and any warnings printed on your bottle.\u003c\/p\u003e\n\u003cp\u003eA practical note: if you also take another Inflameze or Joint Solution formula, add up the turmeric before you stack them (the FAQ below does the math).\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. If you take prescription medication, including blood thinners, show your practitioner or pharmacist the Supplement Facts panel before you start.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cp\u003eWe've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either. Here's what stands behind every bottle of Inflameze Ultra.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, from the turmeric extract to the ginger root, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Inflameze Ultra gets its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps formulators, makers and testers under one roof, and the owners work in the building too.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many Inflameze Ultra capsules are in a serving?\u003c\/h3\u003e\n\u003cp\u003eTwo. The Supplement Facts panel lists a serving as 2 capsules, and each 50-capsule bottle holds 25 servings. Follow the directions printed on your bottle for how often to take it.\u003c\/p\u003e\n\u003ch3\u003eHow long before I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eThere's no set timeline, and we won't make one up. Give Inflameze Ultra a few weeks of steady use at the label's serving, and judge it by your normal week: the stairs, the hike, the yard work.†\u003c\/p\u003e\n\u003ch3\u003eWhich Inflameze is right for me?\u003c\/h3\u003e\n\u003cp\u003eIt depends on how you like your turmeric. The original \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/inflameze-botanical-joint-support\"\u003eInflameze\u003c\/a\u003e spreads each capsule across seven ingredients, including boswellia, bromelain and 50 mg of Curcumin C3 Complex. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/inflameze-advanced-turmeric-joint\"\u003eInflameze Advanced\u003c\/a\u003e centers on 250 mg of CurcuWIN curcumin complex per capsule, plus a blend that includes boswellia and bromelain. Inflameze Ultra has 500 mg of Curcumin C3 Complex per 2-capsule serving with ParActin, organic ginger root and BioPerine, and no boswellia or bromelain. We would pick one, since all three contain turmeric.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with MSM 2000 or Joint Solution Advanced?\u003c\/h3\u003e\n\u003cp\u003eYes, with a little arithmetic. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/msm-2000mg-joint-health-support\"\u003eMSM 2000\u003c\/a\u003e is a single ingredient (2,000 mg of MSM per tablet), so nothing overlaps. A full 4-capsule serving of \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-support-advanced\"\u003eJoint Solution Advanced\u003c\/a\u003e adds 100 mg of Curcumin C3 Complex on top of Ultra's 500 mg, and its label states it contains glucosamine from crab shell. Run any stack past your practitioner.\u003c\/p\u003e\n\u003ch3\u003eWhat makes ParActin different from plain andrographis powder?\u003c\/h3\u003e\n\u003cp\u003eParActin is a leaf extract, not just dried, ground leaf. The panel lists it as a trademarked \u003cem\u003eAndrographis paniculata\u003c\/em\u003e leaf extract and names its bioactive marker, the \"14-Neo-Andro Compound.\" Ours is organic, per the label.\u003c\/p\u003e\n\u003ch3\u003eIs Inflameze Ultra safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, and bring the Supplement Facts panel. Piperine from BioPerine slows one of the steps the liver and gut use to clear compounds, which is how it raises curcumin levels, and it may change how your body handles some medications too.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-mobility-stack-inflameze-msm\"\u003eThe Joint + Mobility Stack: original Inflameze, MSM 2000 and Joint Solution Advanced\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/joint-support-structure-and-comfort\"\u003eJoint Solution, with glucosamine, boswellia and Curcumin C3 Complex\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eTalebi S et al. Nutritional interventions for exercise-induced muscle damage: an umbrella review of systematic reviews and meta-analyses of randomized trials. Nutr Rev. 2024. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37460208\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eOxley RA, Peart DJ. The effect of curcumin supplementation on functional strength outcomes and markers of exercise-induced muscle damage: A systematic review and meta-analysis. Nutr Health. 2023. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37408367\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eShoba G et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9619120\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003ePholphana N et al. Andrographis paniculata: Dissolution investigation and pharmacokinetic studies of four major active diterpenoids after multiple oral dose administration in healthy Thai volunteers. J Ethnopharmacol. 2016. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27702690\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWilson PB. Ginger (Zingiber officinale) as an Analgesic and Ergogenic Aid in Sport: A Systemic Review. J Strength Cond Res. 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26200194\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWilson PB. A Randomized Double-Blind Trial of Ginger Root for Reducing Muscle Soreness and Improving Physical Performance Recovery Among Experienced Recreational Distance Runners. J Diet Suppl. 2018. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30299178\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"50","offer_id":44931026419994,"sku":"015-M1011","price":37.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1011_REV00_Ingredients.png?v=1738258743"},{"product_id":"pure-dhea-25mg","title":"DHEA 25 mg – Supports Mood \u0026 Physical Well-Being | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eDHEA 25 mg from Mt. Angel Vitamins is one vegetarian capsule holding 25 mg of DHEA (dehydroepiandrosterone), an adrenal hormone your body makes less of as the years go by. Each bottle has 60 capsules, a 60-day supply at the label's one capsule a day. It's a single active ingredient that supports mood and physical well-being.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDHEA is for adults, mostly people in their 40s and beyond, whose own DHEA has been drifting down since early adulthood and who want a measured amount with their practitioner in the loop. It is not for anyone under 18 or anyone pregnant or nursing. The label says so in capital letters.\u003c\/p\u003e\n\u003cp\u003eAging isn't optional. Getting old is. DHEA won't turn back the calendar, and we won't pretend the studies say it will. Here's what the research found, encouraging and lukewarm, so you can decide whether 25 mg a day earns a spot in your routine.\u003c\/p\u003e\n\u003ch2\u003eWhy people take DHEA 25 mg\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTo support mood and physical well-being, the benefit printed on the label.†\u003c\/li\u003e\n\u003cli\u003eTo add DHEA, an adrenal hormone whose blood levels peak in early adulthood and then decline steadily with age.†\u003c\/li\u003e\n\u003cli\u003eTo give the body a starting material it converts into other hormones, such as testosterone and estrogen.†\u003c\/li\u003e\n\u003cli\u003eTo support healthy aging as one part of a routine built on sleep, movement and good food.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eDHEA (dehydroepiandrosterone)\u003c\/td\u003e\n\u003ctd\u003e25 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value Not Established. Serving size: 1 Vegetarian Capsule. Each bottle holds 60 capsules, a 60-day supply at the label's serving. Other ingredients: Deep mined calcium phosphate, maltodextrin, vegetable cellulose (preservative-free, from capsule shell), cellulose, magnesium trisilicate, silica, and magnesium stearate. The label also reads \"Single Ingredient\" (one active ingredient, DHEA) and \"HPLC Tested.\" HPLC (high-performance liquid chromatography) is a lab method for measuring how much of a compound a sample contains.\u003c\/p\u003e\n\u003ch2\u003eHow DHEA 25 mg works\u003c\/h2\u003e\n\u003ch3\u003eWhat DHEA is\u003c\/h3\u003e\n\u003cp\u003eDHEA (dehydroepiandrosterone) is a steroid hormone made mainly by your adrenal glands, which sit on top of your kidneys. In the blood it travels with its sulfate form, DHEA-S, which is what the studies below measure. Much of what DHEA does, it does as a starting material: the body converts it into androgens such as testosterone and estrogens such as estradiol. The label calls it \"An Adrenal Hormone,\" and its warnings read like a hormone's, not a vitamin's.\u003c\/p\u003e\n\u003ch3\u003eWhy levels change with age\u003c\/h3\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/6235241\/\"\u003ea study of 1,462 people aged 11 to 89\u003c\/a\u003e, average DHEA-S peaked at ages 20 to 24 in men and 15 to 19 in women, then declined steadily in both. Past age 70, average levels were roughly a fifth of the peak.\u003c\/p\u003e\n\u003ch3\u003eWhy 25 mg in one capsule\u003c\/h3\u003e\n\u003cp\u003eThe trials below that name a dose used 50 mg a day, and in two of them that amount brought DHEA-S back to young-adult levels. One capsule of ours is half that, a measured starting point for you and your practitioner. We won't claim it does everything a 50 mg dose did in a study. And please don't double up on your own: the label says not to exceed the recommended serving.\u003c\/p\u003e\n\u003ch3\u003eWhat the research shows\u003c\/h3\u003e\n\u003cp\u003eOne early trial was small. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7515387\/\"\u003ea 1994 crossover trial in adults aged 40 to 70\u003c\/a\u003e, 13 men and 17 women took 50 mg of DHEA nightly or a placebo for 3 months each. DHEA and DHEA-S reached young-adult levels within 2 weeks, and the researchers reported a rise in perceived physical and psychological well-being in both men (67%) and women (84%). Body fat, insulin sensitivity and libido didn't change.\u003c\/p\u003e\n\u003cp\u003eA larger study gave 280 healthy women and men aged 60 to 79 either 50 mg a day or a placebo for a year. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10760294\/\"\u003ethe year-long DHEAge study\u003c\/a\u003e, DHEA-S returned to \"young\" levels with no potentially harmful build-up of related hormones. Testosterone and estradiol rose a little, and skin hydration and thickness improved, both mainly in women.\u003c\/p\u003e\n\u003ch3\u003eWhat the research doesn't show\u003c\/h3\u003e\n\u003cp\u003eNow the lukewarm part. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9215320\/\"\u003eA 2-week crossover trial in 40 healthy older adults\u003c\/a\u003e (average age 69) found no strong effect of 50 mg a day on well-being, mood or memory tests. Women trended toward better mood, but the difference wasn't statistically significant. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17050889\/\"\u003eA 2-year trial in 87 older men and 57 older women\u003c\/a\u003e with low DHEA-S (56 of them took DHEA) found no meaningful change from DHEA in body composition, muscle strength, physical performance or quality of life. And \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23824417\/\"\u003ea 2013 meta-analysis of 25 placebo-controlled trials in 1,353 older men\u003c\/a\u003e found a small drop in fat mass, but no effect on quality of life, sexual function, bone measures, or blood lipid and glucose markers.\u003c\/p\u003e\n\u003cp\u003eThe honest summary: taking DHEA raises DHEA-S in the blood, study after study, but the effects people feel are modest, and the strongest well-being result came from the smallest trial. It's worth talking over with your practitioner before you start.\u003c\/p\u003e\n\u003ch2\u003eHow to take DHEA 25 mg\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDirections from the label:\u003c\/strong\u003e \"One capsule daily, as a dietary supplement, or as directed by your health care practitioner.\"\u003c\/p\u003e\n\u003cp\u003eThe label doesn't specify a time of day or whether to take it with food, so pick a time you'll remember. Don't take more than one capsule a day unless your practitioner directs it; the label warns that exceeding the recommended serving may cause adverse health effects.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe label's warnings, in plain English:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNot for use by anyone under the age of 18. Do not use if pregnant or nursing.\u003c\/li\u003e\n\u003cli\u003eTalk with a physician or licensed qualified health care professional before using DHEA if you have, or have a family history of, any prostate condition, any heart condition, or low \"good\" cholesterol (HDL).\u003c\/li\u003e\n\u003cli\u003eDo the same if you use any other dietary supplement, prescription drug or over-the-counter drug.\u003c\/li\u003e\n\u003cli\u003ePossible side effects listed on the label: skin breakouts, hair loss, hair growth on the face (in women), aggressiveness, irritability, and increased levels of estrogen.\u003c\/li\u003e\n\u003cli\u003eStop using it and call a physician or licensed qualified health care professional right away if you notice a rapid heartbeat, dizziness, blurred vision or other similar symptoms.\u003c\/li\u003e\n\u003cli\u003eKeep out of reach of children.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eRead the full warning on the bottle before your first capsule. If you take medication or have a medical condition, ask your healthcare practitioner before use.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, DHEA included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA with globally sourced ingredients, in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility is where the formulators, the makers and the testers all work under one roof. The owners work in the building too, and the company has been owner-run since 2017. We've been making supplements in Oregon since 1974, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much DHEA is in each capsule?\u003c\/h3\u003e\n\u003cp\u003eEach vegetarian capsule contains 25 mg of DHEA, and the label's serving is one capsule a day, so a 60-capsule bottle lasts 60 days.\u003c\/p\u003e\n\u003ch3\u003eWhen should I take DHEA, and does it need food?\u003c\/h3\u003e\n\u003cp\u003eThe label doesn't say, so choose a time you'll stick with. The 1994 trial had people take it at night, but that was study design, not a rule. If your practitioner has a preference, follow it.\u003c\/p\u003e\n\u003ch3\u003eHow long before I notice anything?\u003c\/h3\u003e\n\u003cp\u003eThere's no guaranteed timeline, and some people notice nothing. In studies using 50 mg a day, blood DHEA-S rose within about 2 weeks, and well-being was measured after 3 months. If you're unsure whether it's doing anything for you, check in with your practitioner.\u003c\/p\u003e\n\u003ch3\u003eIs DHEA for men or women?\u003c\/h3\u003e\n\u003cp\u003eBoth. Men and women make DHEA, and both took part in the studies above. In the 1994 trial, androgen levels doubled in women taking 50 mg while men saw only a small change. The label lists \"hair growth on the face (in women)\" among possible side effects. It's for adults 18 and older only, and not for use during pregnancy or nursing.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with one of your multivitamins?\u003c\/h3\u003e\n\u003cp\u003eCheck with your practitioner first, since the label asks you to talk with a physician or licensed qualified health care professional before combining DHEA with any other dietary supplement or drug. Our multivitamins don't contain DHEA, so you wouldn't be doubling up, and a multi covers everyday vitamins and minerals that DHEA doesn't.\u003c\/p\u003e\n\u003ch3\u003eIs DHEA safe to take with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your practitioner before you start. The label asks you to consult a physician or licensed qualified health care professional if you use any prescription or over-the-counter drug. Bring the bottle so they can see exactly what's in it.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cp\u003eCompanions to discuss with your practitioner:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-multi-vitamin-60-capsules\"\u003eMen's Multi, a daily multivitamin for men\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-multi-cap-60ct\"\u003eWomen's Multi, a daily multivitamin for women\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-50-plus-multivitamin\"\u003eMen's 50+ Multivitamin, built for men over 50\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-50-plus-multivitamin\"\u003eWomen's 50+ Multivitamin, built for women over 50\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/b-good-com-vitamin-b-complex\"\u003eB-Complex, a vitamin B complex in one daily capsule\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrentreich N et al. Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood. J Clin Endocrinol Metab. 1984. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/6235241\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eMorales AJ et al. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. J Clin Endocrinol Metab. 1994. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7515387\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBaulieu EE et al. Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue. Proc Natl Acad Sci U S A. 2000. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10760294\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWolf OT et al. Effects of a two-week physiological dehydroepiandrosterone substitution on cognitive performance and well-being in healthy elderly women and men. J Clin Endocrinol Metab. 1997. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9215320\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eNair KS et al. DHEA in elderly women and DHEA or testosterone in elderly men. N Engl J Med. 2006. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17050889\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCorona G et al. Dehydroepiandrosterone supplementation in elderly men: a meta-analysis study of placebo-controlled trials. J Clin Endocrinol Metab. 2013. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23824417\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"Default Title","offer_id":49089447756058,"sku":"015-A7006","price":19.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/A7006_REV00_Capsules_Necktag.png?v=1747250119"},{"product_id":"blood-sugar-support-60ct-caps","title":"Blood Sugar Support – For Healthy Glucose Metabolism | 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eBlood Sugar Support is a 60-capsule mealtime formula. Each 2-capsule serving combines 200 mg berberine (from berberine HCl), 200 mg magnesium, 75 mcg chromium, 300 mg psyllium husk, 200 mg apple cider vinegar powder, fenugreek, cinnamon and bitter melon extracts, and 100 mg R-alpha lipoic acid to support healthy blood sugar levels already within the normal range.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis one is for adults whose blood sugar is already in the normal range and who'd like to keep it there as the decades stack up. Maybe you're in your 30s or 40s, you walk after dinner, you read the carb line on labels, and you want a mealtime supplement that backs up those habits. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003cp\u003eIt isn't a stand-in for food, movement or sleep. It's one more mealtime habit. If a practitioner already keeps an eye on your blood sugar, check with them before you start.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Blood Sugar Support\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy blood sugar levels already within the normal range.†\u003c\/li\u003e\n\u003cli\u003eBuilt around mealtime: taken before meals as the label directs, it pairs ingredients studied for the normal post-meal glucose response.†\u003c\/li\u003e\n\u003cli\u003eProvides berberine and R-alpha lipoic acid, two compounds studied for their role in how cells take up and use glucose for energy.†\u003c\/li\u003e\n\u003cli\u003eProvides 200 mg of magnesium and 75 mcg of chromium per serving, two minerals involved in normal carbohydrate metabolism.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium (from magnesium oxide)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003e48%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eChromium (from 600 mcg chromium picolinate)\u003c\/td\u003e\n\u003ctd\u003e75 mcg\u003c\/td\u003e\n\u003ctd\u003e200%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePsyllium (\u003cem\u003ePlantago ovata\u003c\/em\u003e) Husk\u003c\/td\u003e\n\u003ctd\u003e300 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eApple (\u003cem\u003eMalus domestica\u003c\/em\u003e) Cider Vinegar Powder\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBerberine (from berberine HCl)\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFenugreek (\u003cem\u003eTrigonella foenum-graecum\u003c\/em\u003e) Seed 10:1 Extract\u003c\/td\u003e\n\u003ctd\u003e150 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCinnamon (\u003cem\u003eCinnamomum cassia\u003c\/em\u003e) Bark 10:1 Water Extract\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eR-Alpha Lipoic Acid\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBitter Melon (\u003cem\u003eMomordica charantia\u003c\/em\u003e) Fruit 4:1 Extract\u003c\/td\u003e\n\u003ctd\u003e70 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established.\u003c\/p\u003e\n\u003cp\u003eServing size: 2 capsules. Servings per container: 30. Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), magnesium stearate, and silica. The label states: \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow Blood Sugar Support works\u003c\/h2\u003e\n\u003cp\u003eNine ingredients, not all pulling equal weight. Here's what each does, and where our amounts are smaller than the studies.\u003c\/p\u003e\n\u003ch3\u003eBerberine (200 mg from berberine HCl)\u003c\/h3\u003e\n\u003cp\u003eBerberine is a bright yellow compound found in barberry, goldenseal and Oregon grape (yes, our state flower). The panel lists 200 mg of berberine, from berberine HCl, a salt form commonly used in supplements. Its best-known trick is switching on AMPK, an enzyme that acts like a cell's fuel gauge: when it reads low, cells pull in more glucose and burn it. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17049164\/\"\u003ea 2006 study in rat muscle cells\u003c\/a\u003e, berberine raised glucose uptake through AMPK, by a route separate from insulin's usual signal. That's cells in a dish, not people.\u003c\/p\u003e\n\u003cp\u003eThe evidence in healthy adults is thinner than berberine's reputation. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35010998\/\"\u003ea 2021 pilot trial in five healthy young men\u003c\/a\u003e, blood berberine stayed low after 500 mg doses, and glucose and insulin didn't change over the short protocol. The authors note berberine is poorly absorbed and tied to more stomach upset at higher doses. Larger trials exist, but they studied different groups than the healthy adults this product is for, so we don't make promises from them.\u003c\/p\u003e\n\u003ch3\u003eApple cider vinegar powder (200 mg) and psyllium husk (300 mg)\u003c\/h3\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16015276\/\"\u003ea 2005 crossover trial in 12 healthy volunteers\u003c\/a\u003e, adding vinegar to a white bread breakfast lowered the 30-minute blood glucose and insulin responses and raised fullness ratings, and more vinegar meant a bigger effect. The honest limit: that was liquid vinegar in amounts far larger than the 200 mg of powder here, so it shows the direction, not a promise about this dose.\u003c\/p\u003e\n\u003cp\u003ePsyllium husk, from the seed coat of \u003cem\u003ePlantago ovata\u003c\/em\u003e, is a soluble fiber that thickens into a gel in water, which can slow how a meal moves through digestion. Fiber research uses several grams a day, so at 300 mg psyllium is a supporting player, not your fiber for the day.\u003c\/p\u003e\n\u003ch3\u003eFenugreek, cinnamon and bitter melon extracts\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eFenugreek seed 10:1 extract (150 mg).\u003c\/strong\u003e In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26358163\/\"\u003ea 2015 trial in 10 healthy adults\u003c\/a\u003e, swapping 10% of the flour in buns and flatbreads for fenugreek seed powder lowered the post-meal glucose response and dropped the buns' glycemic index from 82 to 51. That was whole seed powder baked into the food, not an extract. Our 150 mg of 10:1 extract starts from roughly 1.5 g of seed, and no trial we know of tested this exact amount.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCinnamon bark 10:1 water extract (100 mg).\u003c\/strong\u003e Cinnamon is a lesson in dose. An earlier trial in healthy adults found 6 g of cinnamon in rice pudding lowered post-meal glucose. Then \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19158209\/\"\u003ea 2009 follow-up in 15 healthy adults\u003c\/a\u003e tried 1 g and 3 g: neither changed post-meal glucose significantly, though 3 g lowered the insulin response. Our extract starts from about 1 g of bark, so cinnamon is a team player here, not the star.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBitter melon fruit 4:1 extract (70 mg).\u003c\/strong\u003e A gourd cooked across South and East Asia, and it earns its name. Researchers have studied its plant compounds for glucose metabolism, but trials in healthy adults are few, so we don't hang any promises on it.\u003c\/p\u003e\n\u003ch3\u003eR-alpha lipoic acid (100 mg)\u003c\/h3\u003e\n\u003cp\u003eAlpha lipoic acid works inside your mitochondria as a helper (a cofactor) for enzymes involved in turning food into usable energy. It comes in two mirror-image forms, R and S, and this label lists the R form, which \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27314343\/\"\u003ea 2016 study in six healthy volunteers\u003c\/a\u003e describes as a cofactor of mitochondrial enzymes. That same study is a useful reality check: a single dose of R-lipoic acid didn't change blood glucose, and no side effects were seen. So R-alpha lipoic acid is a supporting player here, not a promise.\u003c\/p\u003e\n\u003ch3\u003eMagnesium (200 mg) and chromium (75 mcg)\u003c\/h3\u003e\n\u003cp\u003eMagnesium is a cofactor in more than 300 enzyme systems, and \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Magnesium-HealthProfessional\/\"\u003eNIH's magnesium fact sheet\u003c\/a\u003e lists blood glucose control among them. A serving gives 200 mg (48% DV) from magnesium oxide, which is about 60% magnesium by weight. That's how 200 mg fits into two capsules beside eight other ingredients. The trade-off, per the same fact sheet: oxide is absorbed less completely than citrate or chloride forms and is among the forms most often linked to loose stools at higher intakes.\u003c\/p\u003e\n\u003cp\u003eChromium is a trace mineral. In 2001 the U.S. Food and Nutrition Board called it an essential nutrient based on its effects on insulin action, though later reviews have questioned that. Each serving gives 75 mcg from 600 mcg of chromium picolinate. Straight talk: \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Chromium-HealthProfessional\/\"\u003eNIH's chromium fact sheet\u003c\/a\u003e describes inconsistent findings in chromium supplement studies and cites a review that found chromium doesn't help moderate glucose in healthy people. It's a supporting mineral for normal carbohydrate metabolism, not the reason to buy the bottle.†\u003c\/p\u003e\n\u003ch2\u003eHow to take Blood Sugar Support\u003c\/h2\u003e\n\u003cp\u003eThe label directions: \"Take two capsules twenty minutes before each meal, as a dietary supplement.\" Each bottle holds 60 capsules, or 30 servings of 2 capsules.\u003c\/p\u003e\n\u003cp\u003eTake the capsules with a full glass of water, since the formula contains psyllium. Berberine and magnesium oxide can each unsettle some stomachs, so notice how you feel in the first days.\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Blood Sugar Support gets one.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA. Made and tested in Mt. Angel, Oregon.\u003c\/strong\u003e That's a farm town of about 3,500 in the Willamette Valley, and our UL-certified cGMP facility there is where this formula is made and tested. Formulators, makers and testers work under one roof, and the owners work in the building too. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many capsules of Blood Sugar Support should I take?\u003c\/h3\u003e\n\u003cp\u003eFollow the label: \"Take two capsules twenty minutes before each meal, as a dietary supplement.\" One serving is 2 capsules, and the bottle holds 30 servings.\u003c\/p\u003e\n\u003ch3\u003eWhy take it before meals?\u003c\/h3\u003e\n\u003cp\u003eBecause that's what the label directs: two capsules twenty minutes before each meal. The ingredients are there for the meal that follows, and the vinegar, fenugreek and cinnamon studies above all measured the response after a carbohydrate meal.\u003c\/p\u003e\n\u003ch3\u003eHow soon will I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eProbably not in a way you can feel, and that's normal. This isn't a stimulant, and the studies behind these ingredients measured blood values after a meal, not how people felt. If you'd like numbers, ask your practitioner how to check them.\u003c\/p\u003e\n\u003ch3\u003eCan I take Blood Sugar Support with my medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first, and bring the bottle so they can see all nine ingredients and their amounts. Our \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/tools\/interaction-checker\"\u003esupplement and medication interaction checker\u003c\/a\u003e is a good place to start that conversation, not finish it.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Good Magnesium or CoQ10 + Alpha Lipoic Acid?\u003c\/h3\u003e\n\u003cp\u003eCheck the totals first. A serving already gives 200 mg of magnesium, so adding \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium chelate\u003c\/a\u003e raises your total magnesium from supplements, and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/coq10-alpha-lipoic-acid\"\u003eCoQ10 + Alpha Lipoic Acid\u003c\/a\u003e adds more alpha lipoic acid. Your practitioner can help you decide whether the combination makes sense.\u003c\/p\u003e\n\u003ch3\u003eWhat does \"from berberine HCl\" mean on the label?\u003c\/h3\u003e\n\u003cp\u003eIt means the berberine in each serving comes from berberine hydrochloride (HCl), a salt form commonly used in supplements. The panel lists 200 mg of berberine per 2-capsule serving.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/single-bottle-solution-what-is-it-and-why-do-we-put-it-on-our-premium-bottles\"\u003eWhat \"Single Bottle Solution\" on our labels means\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/our-approach-to-raw-material-sourcing-and-testing\"\u003eHow we source and test raw materials before they reach a capsule\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/nmn-nr-cellular-wellness-supplement\"\u003eNMN + NR Cellular Wellness\u003c\/a\u003e, our NAD+ formula, if cellular energy is next on your list\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eCheng Z et al. Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK. Biochim Biophys Acta. 2006. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17049164\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eMoon JM et al. Absorption Kinetics of Berberine and Dihydroberberine and Their Impact on Glycemia: A Randomized, Controlled, Crossover Pilot Trial. Nutrients. 2021. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35010998\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eOstman E et al. Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects. Eur J Clin Nutr. 2005. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16015276\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eRobert SD et al. Reduction of postprandial blood glucose in healthy subjects by buns and flatbreads incorporated with fenugreek seed powder. Eur J Nutr. 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26358163\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eHlebowicz J et al. Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and ghrelin concentrations in healthy subjects. Am J Clin Nutr. 2009. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19158209\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eIkuta N et al. Bioavailability of an R-α-Lipoic Acid\/γ-Cyclodextrin Complex in Healthy Volunteers. Int J Mol Sci. 2016. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27314343\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"Default Title","offer_id":49291286511898,"sku":"015-M7115","price":35.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M7115_REV00_New_Item.png?v=1738258824"},{"product_id":"milk-thistle-60-ct-vegetarian","title":"Milk Thistle 200 mg – Supports Healthy Liver Function | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eMt. Angel Vitamins Milk Thistle is a single-ingredient herbal supplement. Each vegetarian capsule holds 200 mg of milk thistle fruit extract (\u003cem\u003eSilybum marianum\u003c\/em\u003e), standardized to contain 80% silybin\/silymarin, and each bottle has 60 capsules. The label directs one to two capsules twice daily. Milk thistle supports healthy liver function and the liver's normal antioxidant defenses.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eYour liver is one of the body's busiest processing plants. It sorts nutrients and handles the everyday compounds that come in with food and air, whether or not you ever think about it. Milk thistle is the herb people have used to back up that work for a very long time, and this bottle keeps it simple: one herb, one job, no blend to decode.\u003c\/p\u003e\n\u003cp\u003eIt's for adults who want straightforward liver support in their daily routine. Start in your 30s and 40s, when you're already paying attention to how you eat, sleep and move, because the habits you build now are the ones you'll live with in your 70s and 80s.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Milk Thistle\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy liver function.†\u003c\/li\u003e\n\u003cli\u003eSupports the liver's normal antioxidant defenses, helping liver cells handle everyday oxidative stress.†\u003c\/li\u003e\n\u003cli\u003eSilymarin helps cells turn up their own antioxidant enzymes, so it works with your body's defenses instead of acting only as a one-time antioxidant.†\u003c\/li\u003e\n\u003cli\u003eDelivers 200 mg of milk thistle fruit extract per capsule, standardized to 80% silybin\/silymarin, so you know what each capsule is built around.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eMilk Thistle Fruit Extract (\u003cem\u003eSilybum marianum\u003c\/em\u003e), standardized to contain 80% silybin\/silymarin\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 1 Vegetarian Capsule. At one capsule per serving, the 60-capsule bottle holds 60 servings. Other ingredients: Cellulose, vegetable cellulose (preservative-free, from capsule shell), magnesium trisilicate, and magnesium stearate. The label states: \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003cp\u003eAbout those other ingredients: cellulose is plant fiber, the capsule shell is vegetable cellulose, and magnesium trisilicate and magnesium stearate help the powder flow evenly so each capsule fills the same way.\u003c\/p\u003e\n\u003ch2\u003eHow Milk Thistle works\u003c\/h2\u003e\n\u003ch3\u003eMilk thistle, the plant\u003c\/h3\u003e\n\u003cp\u003eMilk thistle is a tall, prickly thistle with purple flower heads and leaves streaked with white veins, native to the Mediterranean. The label says \"fruit extract,\" and that's botanically precise: what most people call milk thistle seeds are tiny dry fruits, and that's where the plant keeps its silymarin.\u003c\/p\u003e\n\u003ch3\u003eSilymarin and the 80% standard\u003c\/h3\u003e\n\u003cp\u003eSilymarin isn't one compound. It's a family of plant compounds called flavonolignans, including silybin A and B, isosilybin A and B, silychristin and silydianin, all measured in human blood after a dose of standardized extract (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17913795\/\"\u003ea study of how silymarin compounds are absorbed and processed\u003c\/a\u003e). Silybin is the headliner. The panel on this bottle notes that silybin is considered the most characteristic and most stable of the flavonolignans in the plant, and this extract is standardized to contain 80% silybin\/silymarin.\u003c\/p\u003e\n\u003cp\u003ePlants vary from field to field and season to season, and standardizing takes that guesswork out. Potency is also one of the four checks every incoming ingredient lot gets before we use it, alongside identity, heavy metals and microbes.\u003c\/p\u003e\n\u003ch3\u003eHow silymarin supports the liver's antioxidant defenses\u003c\/h3\u003e\n\u003cp\u003eLiver cells do a lot of chemistry, and chemistry makes byproducts: reactive molecules called free radicals that cells are constantly cleaning up. Silymarin helps in more than one way. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26785346\/\"\u003eA review of silymarin's antioxidant mechanisms\u003c\/a\u003e concluded that grabbing free radicals directly matters mostly in the gut. Inside cells, the bigger effect is probably indirect: silymarin activates Nrf2, a switch that tells cells to make more of their own antioxidant enzymes and molecules.† Think of it less as a sponge and more as a foreman who gets the crew working.\u003c\/p\u003e\n\u003cp\u003eThe honest limit: most of that mechanism work comes from lab and animal studies. It explains how silymarin can support the liver's normal defenses. It isn't a measurement of what one capsule does in you.\u003c\/p\u003e\n\u003ch3\u003eHow your body absorbs it\u003c\/h3\u003e\n\u003cp\u003eSilymarin moves fast. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17913795\/\"\u003ea small study in three healthy volunteers\u003c\/a\u003e who took a single 600 mg dose of standardized extract, blood levels peaked within about 1 to 3 hours, and most of the silymarin was quickly converted into conjugated forms the body tags for removal. Half-lives were about 1 to 3 hours for the free forms and 3 to 8 hours for the conjugated forms. Three people is a sketch, not a verdict, but short half-lives fit with the label's twice-daily directions.\u003c\/p\u003e\n\u003ch3\u003eWhat the research does and doesn't show\u003c\/h3\u003e\n\u003cp\u003eMost human trials of milk thistle weren't run in healthy adults, so we don't borrow their results for this page. In healthy adults, the human research is mostly about how silymarin is absorbed and how well it's tolerated, not about results you'd feel.\u003c\/p\u003e\n\u003cp\u003eOn tolerance, the record is good. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31069872\/\"\u003eAn updated review of silymarin safety\u003c\/a\u003e found it well tolerated in people, even at 700 mg three times a day for 24 weeks, with occasional stomach upset such as nausea or loose stools. The label's top amount, two capsules twice a day, is 800 mg of extract a day. The same review describes few drug interactions but advises caution with medications that have a narrow safety margin, and urges caution and more study in pregnancy.\u003c\/p\u003e\n\u003cp\u003eOn medications specifically, \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25028567\/\"\u003ea 14-day study in nine healthy volunteers\u003c\/a\u003e taking a standardized milk thistle extract three times a day found no significant change in four major enzymes that process common drugs (CYP1A2, CYP2C9, CYP2D6 and CYP3A4\/5). Nine people and four enzymes don't cover every medication, which is why we still say: check with your practitioner.\u003c\/p\u003e\n\u003ch2\u003eHow to take Milk Thistle\u003c\/h2\u003e\n\u003cp\u003eThe label's directions: \"One to two capsules twice daily, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eThat works out to two to four capsules a day, split into two doses. If you also take another product that contains milk thistle, add up the totals.\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e52 years of making supplements.\u003c\/strong\u003e We've been making supplements in Oregon since 1974.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot, milk thistle extract included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Milk Thistle has one. To see what one looks like, browse \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\"\u003ethe certificates of analysis we've published for other products\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA, in Mt. Angel, Oregon, with globally sourced ingredients.\u003c\/strong\u003e Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. We make and test Milk Thistle in our UL-certified cGMP facility there, where the formulators, the makers and the testers work under one roof, and the owners work in the building too. Owner-run since 2017, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eWhat does \"standardized to 80% silybin\/silymarin\" mean?\u003c\/h3\u003e\n\u003cp\u003eIt means the 200 mg of extract in each capsule is held to a set content of its key compounds: 80% silybin\/silymarin. Milk thistle plants vary, so standardizing is how you get the same capsule from bottle to bottle instead of whatever a given harvest produced.\u003c\/p\u003e\n\u003ch3\u003eHow many Milk Thistle capsules should I take a day?\u003c\/h3\u003e\n\u003cp\u003eFollow the label: one to two capsules twice daily. That's two to four capsules, or 400 to 800 mg of milk thistle fruit extract, a day. Starting at the low end and seeing how your stomach likes it is a sensible way to begin.\u003c\/p\u003e\n\u003ch3\u003eShould I take milk thistle with food?\u003c\/h3\u003e\n\u003cp\u003eThe label doesn't say either way, so take it however you'll remember it. Pairing the two doses with breakfast and dinner makes them easy to remember. If capsules on an empty stomach ever bother you, try them with a meal.\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eHonestly, you may never feel it, and that's normal for liver support. Milk thistle supports work your liver is already doing quietly, so think of it as a steady daily habit rather than something with a moment you'll notice.†\u003c\/p\u003e\n\u003ch3\u003eCan I take Milk Thistle with D-Tox or Liv'R Support?\u003c\/h3\u003e\n\u003cp\u003eYou can, but know that both already contain milk thistle. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/d-tox-healthy-liver-support\"\u003eD-Tox, our multi-ingredient liver support formula\u003c\/a\u003e, has 200 mg of milk thistle seed extract in each 2-capsule serving, alongside NAC and three roots. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/livr-support-liver-detox-cleanse\"\u003eLiv'R Support, our broader liver formula with choline and carnitine\u003c\/a\u003e, has 25 mg of milk thistle extract in each 2-capsule serving. If you combine them, add up the milk thistle and run the total by your practitioner.\u003c\/p\u003e\n\u003ch3\u003eIs milk thistle safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your practitioner before you start. Studies so far show few interactions, but they're small, and caution is advised with medications that have a narrow safety margin. Your practitioner knows your medication list. We don't.\u003c\/p\u003e\n\u003ch3\u003eIs Milk Thistle a detox or a cleanse?\u003c\/h3\u003e\n\u003cp\u003eNot in the cleanse sense. It doesn't flush or purge anything. Your liver does the everyday work of processing compounds and clearing them out on its own, and milk thistle supports that normal function.†\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eWen Z et al. Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract. Drug Metab Dispos. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17913795\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSurai PF. Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives. Antioxidants (Basel). 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26785346\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSoleimani V et al. Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review. Phytother Res. 2019. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31069872\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKawaguchi-Suzuki M et al. The effects of milk thistle (Silybum marianum) on human cytochrome P450 activity. Drug Metab Dispos. 2014. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25028567\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"Default Title","offer_id":49630166647066,"sku":"015-M1210","price":19.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1210_REV00_New_Item.png?v=1738258859"},{"product_id":"livr-support-liver-detox-cleanse","title":"LIV'R Support – Supports Healthy Liver Function | 60 Vegetarian Capsules","description":"\u003cp\u003e\u003cstrong\u003eLIV'R Support is a liver formula with 300 mg of choline, 250 mg of carnitine, 150 mg each of L-methionine and inositol, 5 mg of vitamin B6, 50 mcg of chromium, 25 mg of milk thistle extract (80% silymarin) and 15 mg of Curcumin C3 Complex® per 2-capsule serving, plus eight plant ingredients at 0.5 to 15 mg each. Each bottle holds 60 vegetarian capsules. It supports healthy liver function.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eYour liver packages fat for transport, stores fuel and processes nearly everything you eat and drink. LIV'R Support backs that work with nutrients the liver uses, like choline and carnitine, plus traditional liver herbs.† It's an easy daily habit to start in your 30s and 40s. One candid note: it isn't a cleanse and doesn't flush anything out.\u003c\/p\u003e\n\u003ch2\u003eWhy people take LIV'R Support\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy liver function.†\u003c\/li\u003e\n\u003cli\u003eProvides 300 mg of choline (54% DV), which your liver uses to package fat and move it out.†\u003c\/li\u003e\n\u003cli\u003eSupports normal fat metabolism and energy production with 250 mg of carnitine.†\u003c\/li\u003e\n\u003cli\u003eAdds vitamin B6 and chromium to support normal protein and carbohydrate metabolism.†\u003c\/li\u003e\n\u003cli\u003eIncludes milk thistle extract and Curcumin C3 Complex® with Bioperine®, plant extracts studied for their antioxidant activity.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B6 (from pyridoxine HCl)\u003c\/td\u003e\n\u003ctd\u003e5 mg\u003c\/td\u003e\n\u003ctd\u003e294%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCholine (from 655 mg choline bitartrate)\u003c\/td\u003e\n\u003ctd\u003e300 mg\u003c\/td\u003e\n\u003ctd\u003e54%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eChromium (picolinate)\u003c\/td\u003e\n\u003ctd\u003e50 mcg\u003c\/td\u003e\n\u003ctd\u003e142%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCarnitine (from L-carnitine tartrate)\u003c\/td\u003e\n\u003ctd\u003e250 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eL-Methionine\u003c\/td\u003e\n\u003ctd\u003e150 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInositol\u003c\/td\u003e\n\u003ctd\u003e150 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMilk Thistle Standardized Extract (from \u003cem\u003eSilybum marianum\u003c\/em\u003e fruit, containing 80% silymarin)\u003c\/td\u003e\n\u003ctd\u003e25 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDandelion Root (\u003cem\u003eTaraxacum officinale\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eArtichoke Leaf (\u003cem\u003eCynara scolymus\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOregon Grape Root (\u003cem\u003eMahonia aquifolium\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCurcumin C3 Complex®\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBoldo Leaf (\u003cem\u003ePeumus boldo\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSchizandra Berry (\u003cem\u003eSchisandra chinensis\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e15 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGotu Kola Herb (\u003cem\u003eCentella asiatica\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e12.5 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBromelain 1200 GDU\/g (from \u003cem\u003eAnanas comosus\u003c\/em\u003e fruit)\u003c\/td\u003e\n\u003ctd\u003e12.5 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBioperine®\u003c\/td\u003e\n\u003ctd\u003e0.5 mg\u003c\/td\u003e\n\u003ctd\u003eNot established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eServing size: 2 Vegetarian Capsules. Servings per container: 30. Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), magnesium trisilicate, silica, magnesium stearate, and cellulose.\u003c\/p\u003e\n\u003ch2\u003eHow LIV'R Support works\u003c\/h2\u003e\n\u003ch3\u003eCholine: 300 mg, from choline bitartrate\u003c\/h3\u003e\n\u003cp\u003eCholine is an essential nutrient. Your liver makes some, but not enough to meet your needs, per the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Choline-HealthProfessional\/\"\u003eNIH choline fact sheet\u003c\/a\u003e, and most people in the United States get less than the Adequate Intake (550 mg a day for men, 425 mg for women). The liver uses choline to build phosphatidylcholine, which it needs to package fat and ship it out.† Choline bitartrate is one of the main forms of choline in supplements.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17490963\/\"\u003ea controlled feeding study of 57 healthy adults\u003c\/a\u003e fed almost no choline for up to 42 days, most of the men and postmenopausal women showed signs that their liver or muscles weren't working normally, and normal function returned once choline was added back. That shows why choline matters, not what an extra 300 mg does if you already eat plenty.\u003c\/p\u003e\n\u003ch3\u003eCarnitine: 250 mg, from L-carnitine tartrate\u003c\/h3\u003e\n\u003cp\u003eIf choline helps the liver move fat out, carnitine helps cells burn it. It carries long-chain fatty acids into mitochondria to be turned into energy, per the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Carnitine-HealthProfessional\/\"\u003eNIH carnitine fact sheet\u003c\/a\u003e.† Healthy adults make their own from lysine and methionine, so the 250 mg here adds to that supply. L-carnitine tartrate supplies L-carnitine, one of the two main forms of carnitine found in supplements.\u003c\/p\u003e\n\u003ch3\u003eL-methionine and inositol: 150 mg each\u003c\/h3\u003e\n\u003cp\u003eMethionine is an essential amino acid, and the NIH choline fact sheet notes that how much methionine you get affects how much choline you need. Inositol is a building block of cell-membrane phospholipids. Research on these exact amounts is limited, so they're supporting cast.\u003c\/p\u003e\n\u003ch3\u003eVitamin B6 and chromium\u003c\/h3\u003e\n\u003cp\u003eVitamin B6 comes as pyridoxine HCl, the most common supplement form per the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/VitaminB6-HealthProfessional\/\"\u003eNIH vitamin B6 fact sheet\u003c\/a\u003e. Your body converts it to coenzymes used in more than 100 enzyme reactions, mostly in protein metabolism.† The 5 mg here is well under the adult upper limit of 100 mg a day. Chromium picolinate supplies chromium, which the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Chromium-HealthProfessional\/\"\u003eNIH chromium fact sheet\u003c\/a\u003e says may play a role in how your body handles carbohydrate, fat and protein by boosting insulin's action.†\u003c\/p\u003e\n\u003ch3\u003eMilk thistle extract: 25 mg, 80% silymarin\u003c\/h3\u003e\n\u003cp\u003eMilk thistle's fruit (often called the seed) is a traditional liver herb. At 80% silymarin (its main group of compounds), each serving carries about 20 mg of silymarin. Straight talk: that's a modest amount. If milk thistle is what you're after, our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/milk-thistle-60-ct-vegetarian\"\u003esingle-herb Milk Thistle, with 200 mg of extract per capsule\u003c\/a\u003e, is the more direct pick. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31069872\/\"\u003eAn updated review of silymarin safety\u003c\/a\u003e found it well tolerated even at 700 mg three times a day for 24 weeks, with occasional stomach upset.\u003c\/p\u003e\n\u003ch3\u003eCurcumin C3 Complex® with Bioperine®: 15 mg and 0.5 mg\u003c\/h3\u003e\n\u003cp\u003eCurcumin C3 Complex® is a turmeric extract with at least 95% curcuminoids, per the label. The catch is absorption. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9619120\/\"\u003ean early study in healthy volunteers\u003c\/a\u003e, 2 g of curcumin alone left blood levels very low or undetectable, while adding 20 mg of piperine, the black pepper compound in Bioperine®, raised bioavailability by 2000%. The amounts here are far smaller, so that's the logic of the pairing, not a promise of those numbers.\u003c\/p\u003e\n\u003cp\u003eIn \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23013352\/\"\u003ea 4-week placebo-controlled trial in 38 healthy adults aged 40 to 60\u003c\/a\u003e, 80 mg a day of a lipidated curcumin raised activity of catalase, an antioxidant enzyme your body makes, and the antioxidant capacity of saliva; placebo didn't. It was small, short and used a different form at over five times this amount, so we don't claim those results here.†\u003c\/p\u003e\n\u003ch3\u003eThe traditional herbs: 12.5 to 15 mg each\u003c\/h3\u003e\n\u003cp\u003eThe rest are herbs with long traditional use, plus one plant enzyme: dandelion root and artichoke leaf (classic European bitters), boldo leaf (from a Chilean shrub), Oregon grape root (the plant is Oregon's state flower), schizandra berry (traditional Chinese practice), gotu kola (Ayurvedic tradition) and bromelain (pineapple enzymes, 1200 GDU\/g). These are small amounts, so they're traditional companions, with no separate promises attached.\u003c\/p\u003e\n\u003ch2\u003eHow to take LIV'R Support\u003c\/h2\u003e\n\u003cp\u003eThe label's directions: \"One capsule, twice daily with meals, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eFor example, one with breakfast and one with dinner. Taking a multivitamin or another liver formula too? Add up your B6, chromium and milk thistle totals.\u003c\/p\u003e\n\u003cp\u003eThe label warns: \"WARNING: Not recommended while pregnant or lactating unless directed by health care practitioner.\" It also carries this California Proposition 65 warning: \"WARNING: This product can expose you to chemicals including Lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.\"\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e52 years and counting.\u003c\/strong\u003e We've been making supplements in Oregon since 1974, and we're not getting old either.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e LIV'R Support included, and you can browse \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/reviews\/lab-testing\"\u003ecertificates of analysis published for other products\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA with globally sourced ingredients, in Mt. Angel, Oregon.\u003c\/strong\u003e Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps formulators, makers and testers under one roof, and it's been owner-run since 2017, with the owners working in the building. Here's \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/why-choose-us\"\u003ehow we make and test our supplements\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many LIV'R Support capsules do I take a day?\u003c\/h3\u003e\n\u003cp\u003eTwo: one capsule twice daily with meals, per the label. That's one serving a day, so a 60-capsule bottle lasts 30 days.\u003c\/p\u003e\n\u003ch3\u003eIs LIV'R Support a detox or a cleanse?\u003c\/h3\u003e\n\u003cp\u003eNo. It doesn't flush anything out of you. Your liver does its own processing around the clock, and LIV'R Support supplies nutrients that support its normal function.†\u003c\/p\u003e\n\u003ch3\u003eHow is LIV'R Support different from Milk Thistle and D-Tox?\u003c\/h3\u003e\n\u003cp\u003eLIV'R Support leads with 300 mg of choline and 250 mg of carnitine, with herbs in smaller amounts. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/milk-thistle-60-ct-vegetarian\"\u003eMilk Thistle\u003c\/a\u003e is a single herb at 200 mg of extract per capsule. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/d-tox-healthy-liver-support\"\u003eD-Tox\u003c\/a\u003e has 200 mg each of NAC, milk thistle extract, dandelion root, burdock root and Oregon grape root per 2-capsule serving, plus DIM and D-limonene. If you combine them, you'd double up on milk thistle and other herbs, so add up the totals and check with your practitioner.\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eYou may not feel anything, and that's expected, because your liver works out of sight. Think of LIV'R Support as a daily habit, not a quick fix.\u003c\/p\u003e\n\u003ch3\u003eIs LIV'R Support safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner or pharmacist first. The silymarin review above advises caution with drugs that have a narrow therapeutic window, and piperine slows one of the ways the liver and gut clear compounds, which could affect some medications too.\u003c\/p\u003e\n\u003ch3\u003eWhy does the label carry a Prop 65 warning?\u003c\/h3\u003e\n\u003cp\u003eCalifornia's Proposition 65 calls for a warning when a product could expose someone to a listed chemical, such as lead, above levels the state sets. We repeat our label's warning word for word above.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eFischer LM et al. Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr. 2007. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17490963\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSoleimani V et al. Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review. Phytother Res. 2019. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31069872\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eShoba G et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9619120\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDiSilvestro RA et al. Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people. Nutr J. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23013352\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"Default Title","offer_id":50650805698842,"sku":"015-M1152","price":25.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M1152_REV00_New_Item_Badge.png?v=1747783942"},{"product_id":"3-in-1-probiotic-fusion","title":"3-in-1 Probiotic Fusion – Pre, Pro \u0026 Postbiotic Gut Support | 30 or 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003e3-in-1 Probiotic Fusion puts a prebiotic, a probiotic and a postbiotic in one vegetarian capsule: 13 lactobacillus and bifidobacterium cultures adding up to about 20 billion CFU, 100 mg of FOS (fructooligosaccharides), 5 billion TFU of Akkermansia muciniphila postbiotic and 25 mg of champignon mushroom extract. You take one capsule a day, from a bottle of 30 or 60, to support healthy digestion and gut balance.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis one is for adults who'd rather take one capsule than three bottles. Most gut routines mean buying a probiotic, then a fiber, then wondering about the postbiotic everyone keeps mentioning. Here all three share a single capsule you take with breakfast or lunch.\u003c\/p\u003e\n\u003cp\u003eBuilding habits in your 30s and 40s that you plan to keep for decades? A daily probiotic is one of the easy ones. It isn't a fix for anything, and below we're straight with you about where the research is solid and where it runs thin.\u003c\/p\u003e\n\u003ch2\u003eWhy people take 3-in-1 Probiotic Fusion\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports digestive balance with 13 probiotic cultures, about 20 billion CFU in every capsule.†\u003c\/li\u003e\n\u003cli\u003eSupports regular, comfortable digestion as part of a daily routine.†\u003c\/li\u003e\n\u003cli\u003eSupplies 100 mg of FOS, a prebiotic fiber that bifidobacteria use as food.†\u003c\/li\u003e\n\u003cli\u003eAdds 5 billion TFU of Akkermansia muciniphila postbiotic, from a microbe that lives in the gut's mucus layer, to support a healthy gut lining.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus Rhamnosus LRa-05\u003c\/td\u003e\n\u003ctd\u003e5 billion CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus Reuteri LR08\u003c\/td\u003e\n\u003ctd\u003e4 billion CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus casei\u003c\/td\u003e\n\u003ctd\u003e1.3 billion CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus paracasei\u003c\/td\u003e\n\u003ctd\u003e1.3 billion CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus plantarum\u003c\/td\u003e\n\u003ctd\u003e1.3 billion CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBifidobacterium bifidum\u003c\/td\u003e\n\u003ctd\u003e1.3 billion CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBifidobacterium breve\u003c\/td\u003e\n\u003ctd\u003e1.3 billion CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBifidobacterium lactis\u003c\/td\u003e\n\u003ctd\u003e1.3 billion CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus acidophilus\u003c\/td\u003e\n\u003ctd\u003e650 million CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBifidobacterium longum\u003c\/td\u003e\n\u003ctd\u003e650 million CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBifidobacterium infantis\u003c\/td\u003e\n\u003ctd\u003e650 million CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus gasseri\u003c\/td\u003e\n\u003ctd\u003e650 million CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus salivarius\u003c\/td\u003e\n\u003ctd\u003e650 million CFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFOS (fructooligosaccharides)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAkkermansia muciniphila Postbiotic\u003c\/td\u003e\n\u003ctd\u003e5 billion TFU\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eChampignon Mushroom 100:1 extract (2,500 mg Agaricus bisporus)\u003c\/td\u003e\n\u003ctd\u003e25 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established.\u003c\/p\u003e\n\u003cp\u003eServing size is 1 Vegetarian Capsule, so the 30-count bottle is a 30-day supply and the 60-count bottle a 60-day supply at the label's serving. The label lists each culture rather than a total; added up, the 13 amounts come to 20.05 billion CFU. Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), cellulose, silica, and L-leucine. The label states: \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\"\u003c\/p\u003e\n\u003ch2\u003eHow 3-in-1 Probiotic Fusion works\u003c\/h2\u003e\n\u003ch3\u003eThe probiotic: 13 cultures, about 20 billion CFU\u003c\/h3\u003e\n\u003cp\u003eProbiotics are live microbes taken in amounts meant to do you some good. CFU (colony forming units) counts cells that can still grow, the right measure for something that's supposed to be alive. Almost half the total comes from the two cultures with strain codes on the label, L. rhamnosus LRa-05 (5 billion CFU) and L. reuteri LR08 (4 billion). Looking them up? Since a 2020 renaming, recent papers call them Lacticaseibacillus rhamnosus and Limosilactobacillus reuteri. Same bacteria, longer names.\u003c\/p\u003e\n\u003cp\u003eWhat the research shows: a review of 45 trials in healthy adults found that probiotics raised levels of the specific bacteria people took, with support for better stool consistency and bowel movements. The rise was temporary, and the review found no support for lasting changes to the gut microbiota (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29581563\/\"\u003ea review of probiotics in healthy adults\u003c\/a\u003e). Those trials used many different strains, not this formula. Because the rise didn't last, a probiotic works as a daily habit, not a one-time fix.†\u003c\/p\u003e\n\u003ch3\u003eThe prebiotic: 100 mg of FOS\u003c\/h3\u003e\n\u003cp\u003eFOS are short chains of fructose your small intestine can't digest. They reach the colon intact, where bacteria ferment them, and bifidobacteria are especially fond of them. That makes FOS a prebiotic: food for the microbes rather than for you.†\u003c\/p\u003e\n\u003cp\u003eThe candid part: in a one-week trial, 40 healthy volunteers took 0 to 20 grams of short-chain FOS a day. Bifidobacteria rose significantly at 10 grams, and 20 grams brought noticeably more gas (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9915885\/\"\u003ea dose-response trial of FOS in healthy volunteers\u003c\/a\u003e). The 100 mg here is one percent of that 10 grams, a little food packed in with the bacteria, not a fiber supplement.\u003c\/p\u003e\n\u003ch3\u003eThe postbiotic: 5 billion TFU of Akkermansia muciniphila\u003c\/h3\u003e\n\u003cp\u003eAn international expert panel defined a postbiotic as a preparation of non-living microbes, or their parts, that gives a health benefit to the person who takes it (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33948025\/\"\u003ethe expert consensus definition of postbiotics\u003c\/a\u003e). So unlike the probiotics, the Akkermansia here isn't meant to be alive. It's counted in TFU (total fluorescent units): cells are stained and counted one by one by a flow cytometer, alive or not, while CFU only counts cells that can still grow.\u003c\/p\u003e\n\u003cp\u003eAkkermansia muciniphila was first described in 2004, after researchers isolated it from human stool using mucin as its only food source (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15388697\/\"\u003ethe original description of Akkermansia muciniphila\u003c\/a\u003e). Mucin is the main building block of the mucus layer that lines your gut. Why would a non-living cell matter? In lab tests on human cells, a protein from Akkermansia's outer surface, Amuc_1100, made layers of gut-lining cells hold together more tightly (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28249045\/\"\u003ea lab study of an Akkermansia surface protein\u003c\/a\u003e). That's cell-culture work, not a human trial.†\u003c\/p\u003e\n\u003cp\u003eFor context on amount: in 2021 the European Food Safety Authority's nutrition panel concluded that a pasteurized Akkermansia muciniphila ingredient is safe at up to 34 billion cells a day for adults, not including pregnant or breastfeeding women (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34484452\/\"\u003ethe EFSA safety opinion on pasteurized Akkermansia\u003c\/a\u003e). That opinion covered that specific ingredient, not this capsule, which has 5 billion TFU per serving. Human research on what Akkermansia does is still early, so we stick to what the label and the studies above show.\u003c\/p\u003e\n\u003ch3\u003eChampignon extract and the rest\u003c\/h3\u003e\n\u003cp\u003eChampignon is French for mushroom; here it's the everyday button mushroom, Agaricus bisporus, as 25 mg of a 100:1 extract the label equates to 2,500 mg of mushroom. Human research on it is thin, so we don't attach a benefit claim to it. Cellulose fills out the capsule, and silica and L-leucine, an amino acid, keep the powder flowing through the capsule machine.\u003c\/p\u003e\n\u003ch2\u003eHow to take 3-in-1 Probiotic Fusion\u003c\/h2\u003e\n\u003cp\u003eLabel directions: \"Take one capsule daily with the morning or noonday meal, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003ePick breakfast or lunch and take it with that same meal each day, so it's easy to remember.\u003c\/p\u003e\n\u003cp\u003eAsk your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of 3-in-1 Probiotic Fusion gets its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA with globally sourced ingredients, in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility is where this capsule is formulated, made and tested, with the formulators, makers and testers all under one roof. The owners work in the building too, and have run the company since 2017. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow many CFU are in 3-in-1 Probiotic Fusion?\u003c\/h3\u003e\n\u003cp\u003eEach capsule has about 20 billion CFU from 13 lactobacillus and bifidobacterium cultures, or 20.05 billion when you add up the label's amounts.\u003c\/p\u003e\n\u003ch3\u003eWhen should I take it?\u003c\/h3\u003e\n\u003cp\u003eTake one capsule a day with your morning or noonday meal, as the label directs. Pick whichever meal you'll remember.\u003c\/p\u003e\n\u003ch3\u003eWhat's the difference between a prebiotic, a probiotic and a postbiotic?\u003c\/h3\u003e\n\u003cp\u003eA probiotic is live bacteria, a prebiotic is food for those bacteria, and a postbiotic is a non-living microbial preparation. Here that's the 13 cultures, the FOS and the Akkermansia.\u003c\/p\u003e\n\u003ch3\u003eHow long until I notice anything?\u003c\/h3\u003e\n\u003cp\u003eWe can't give you a timeline, because no study of this exact formula sets one. Take it daily and pay attention to how your digestion feels over the following weeks. In the review of healthy adults, the rise in supplied bacteria was temporary, so the daily habit is the point.\u003c\/p\u003e\n\u003ch3\u003eDoes it contain milk, soy or gluten?\u003c\/h3\u003e\n\u003cp\u003eNo, according to the label, which states \"NO corn, soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" The capsule is vegetarian.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Super Enzymes+ or Betaine HCl?\u003c\/h3\u003e\n\u003cp\u003eThey do different jobs, and all three labels say to take them with a meal. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/super-enzymes-plus\"\u003eSuper Enzymes+\u003c\/a\u003e is a digestive enzyme blend taken with each meal, and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/betaine-hcl-stomach-digestion\"\u003eBetaine HCl\u003c\/a\u003e is a source of hydrochloric acid taken with or right after a meal, while this capsule supplies bacteria and their food. Follow each label's directions, and if you take medication or have a medical condition, check the combination with your healthcare practitioner first.\u003c\/p\u003e\n\u003ch3\u003eIs it safe with my medication, or while pregnant?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first. That goes double for pregnancy and breastfeeding, since European food-safety reviewers left those groups out of their safety conclusion on pasteurized Akkermansia.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/our-approach-to-raw-material-sourcing-and-testing\"\u003eHow we source and test raw materials before they reach a bottle\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/super-enzymes-plus\"\u003eSuper Enzymes+, a digestive enzyme blend for fats, proteins and carbs\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/betaine-hcl-stomach-digestion\"\u003eBetaine HCl, a source of hydrochloric acid taken with meals\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eKhalesi S et al. A review of probiotic supplementation in healthy adults: helpful or hype? European journal of clinical nutrition. 2019. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29581563\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBouhnik Y et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. The Journal of nutrition. 1999. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9915885\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSalminen S et al. The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics. Nature reviews. Gastroenterology \u0026amp; hepatology. 2021. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33948025\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDerrien M et al. Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. International journal of systematic and evolutionary microbiology. 2004. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15388697\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eOttman N et al. Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function. PloS one. 2017. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28249045\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eEFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) et al. Safety of pasteurised Akkermansia muciniphila as a novel food pursuant to Regulation (EU) 2015\/2283. EFSA journal. European Food Safety Authority. 2021. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34484452\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"30","offer_id":50995384025370,"sku":"015-M3100-30","price":41.99,"currency_code":"USD","in_stock":true},{"title":"60","offer_id":50995384058138,"sku":"015-M3100","price":71.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M3100_REV00_NewItemBadge.png?v=1756135295"},{"product_id":"g-t-f-chromium-chromium-polynicotinate-with-niacin-for-blood-sugar-support-60-capsules","title":"G.T.F. Chromium 200 mcg – Supports Healthy Blood Sugar Levels | 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eG.T.F. Chromium is a one-a-day capsule with 200 mcg of chromium (from 2,000 mcg chromium polynicotinate, 571% DV) and 10 mg of niacin (62% DV). Chromium works with insulin, the hormone that moves glucose from your blood into your cells, so it supports healthy blood sugar levels already within the normal range.† Each bottle holds 60 capsules, a 60-day supply.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBlood sugar is one of those things almost nobody thinks about in their 30s and 40s. G.T.F. Chromium is for people who would rather pay attention early: you eat reasonably well, you move, and you want the small nutrients behind steady energy and normal metabolism covered. Aging isn't optional. Getting old is. Keeping your metabolism in good working order is part of staying on the right side of that line.†\u003c\/p\u003e\n\u003cp\u003eIt's also worth a look if your diet leans on sugar. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3713513\/\"\u003ea controlled feeding study in 37 adults\u003c\/a\u003e, six weeks of high-sugar meals, compared with a lower-sugar reference diet, raised the chromium people lost in their urine, by 10% to 300% in 27 of them. If a doctor already manages your blood sugar, start with a conversation with them, not with this bottle.\u003c\/p\u003e\n\u003ch2\u003eWhy people take G.T.F. Chromium\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy blood sugar levels already within the normal range.†\u003c\/li\u003e\n\u003cli\u003eWorks with insulin to help move glucose from your blood into your cells.†\u003c\/li\u003e\n\u003cli\u003eSupports normal metabolism of carbohydrates, fats and protein.†\u003c\/li\u003e\n\u003cli\u003eNiacin (vitamin B3) supports energy production: your body turns it into NAD, a coenzyme that hundreds of enzymes need.†\u003c\/li\u003e\n\u003cli\u003eDelivers chromium as chromium polynicotinate, chromium bound to niacin, in one capsule a day.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eNiacin\u003c\/td\u003e\n\u003ctd\u003e10 mg NE\u003c\/td\u003e\n\u003ctd\u003e62%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eChromium G.T.F (from 2,000 mcg chromium polynicotinate)\u003c\/td\u003e\n\u003ctd\u003e200 mcg\u003c\/td\u003e\n\u003ctd\u003e571%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eServing size:\u003c\/strong\u003e 1 capsule. A bottle holds 60 capsules, a 60-day supply at the label's serving. \u003cstrong\u003eOther ingredients:\u003c\/strong\u003e Deep mined calcium phosphate, cellulose, gelatin (100% natural, preservative-free, from capsule shell), magnesium trisilicate, magnesium stearate, and silica. \u003cstrong\u003eLabel statements:\u003c\/strong\u003e \"NO soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\" and \"Niacin is included in this formula for maximum uptake and assimilation of Chromium.\"†\u003c\/p\u003e\n\u003ch2\u003eHow G.T.F. Chromium works\u003c\/h2\u003e\n\u003ch3\u003eChromium: insulin's quiet helper\u003c\/h3\u003e\n\u003cp\u003eChromium is a trace mineral found in small, unpredictable amounts in meats, grain products, fruits, vegetables, nuts and spices. How much any given food has depends on the soil and water where it was grown and how it was processed. When insulin tells a cell to take in glucose, chromium appears to amplify that signal. One proposed explanation, laid out in \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10736319\/\"\u003ea review of chromium's biochemistry\u003c\/a\u003e: a small chromium-binding peptide called chromodulin loads up with chromium, then binds to the insulin receptor and turns up its activity. That's why chromium comes up whenever people talk about how the body handles carbohydrates, fats and protein.†\u003c\/p\u003e\n\u003cp\u003eA few honest numbers from the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Chromium-HealthProfessional\/\"\u003eNIH chromium fact sheet\u003c\/a\u003e. The Daily Value is 35 mcg, and the adequate intake for adults runs from 20 to 35 mcg depending on age and sex (a bit higher while breastfeeding). Your body absorbs only about 0.4% to 2.5% of the chromium in food. And scientists still debate how essential chromium is: the U.S. Food and Nutrition Board called it essential in 2001, while a European panel concluded in 2014 that the evidence wasn't convincing. We would rather you hear that from us.\u003c\/p\u003e\n\u003ch3\u003eWhy chromium polynicotinate (the \"G.T.F.\" part)\u003c\/h3\u003e\n\u003cp\u003eG.T.F. stands for glucose tolerance factor. Decades ago, researchers proposed that chromium helps insulin do its job through a special chromium compound by that name. The candid footnote, from \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30032219\/\"\u003ea 2018 review of chromium in Advances in Nutrition\u003c\/a\u003e: attempts to identify a glucose tolerance factor never produced a chemically defined compound that fits that role. Chromium polynicotinate is chromium bound to niacin, and the label names this ingredient Chromium G.T.F. Each capsule gets its 200 mcg of chromium from 2,000 mcg of chromium polynicotinate, so chromium makes up about a tenth of that ingredient by weight. The label lists the chromium itself, which is the number that counts.\u003c\/p\u003e\n\u003cp\u003eDoes the form matter? The candid version: the NIH notes that absorption looks similar across chromium forms, so we won't tell you polynicotinate absorbs dramatically better. We use it because it pairs chromium with niacin, the pairing this formula is built around.\u003c\/p\u003e\n\u003ch3\u003eNiacin: the partner\u003c\/h3\u003e\n\u003cp\u003eNiacin is vitamin B3. Your body turns it into NAD, a coenzyme that more than 400 enzymes rely on, many of them the ones that pull energy out of carbs, fats and protein, according to the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\"\u003eNIH niacin fact sheet\u003c\/a\u003e. Each capsule has 10 mg, 62% of the Daily Value.†\u003c\/p\u003e\n\u003cp\u003eHuman research on the chromium and niacin pairing itself is limited to a few small, older studies. So think of the pairing as a sensible design choice rooted in the G.T.F. idea, not a proven upgrade.\u003c\/p\u003e\n\u003ch3\u003eWhat the research doesn't show\u003c\/h3\u003e\n\u003cp\u003eChromium isn't a lever that pushes normal numbers lower. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10819315\/\"\u003ean 8-week placebo-controlled trial in 19 healthy adults aged 63 to 77\u003c\/a\u003e, 1,000 mcg a day of chromium picolinate made no difference to insulin sensitivity, blood lipids or body composition compared with placebo. Our read: chromium is about keeping a trace mineral covered alongside a good diet, since the amount in food varies so much, not about chasing a number.†\u003c\/p\u003e\n\u003ch2\u003eHow to take G.T.F. Chromium\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDirections (from the label):\u003c\/strong\u003e One capsule daily with a meal, as a dietary supplement.\u003c\/p\u003e\n\u003cp\u003ePick a meal you never skip so it becomes a habit. Taking it with food also keeps the niacin comfortable: 10 mg is well below the 30 to 50 mg of nicotinic acid where flushing typically starts.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLabel warning, in plain terms:\u003c\/strong\u003e if you are under a doctor's care for your blood sugar, use this product only under a physician's supervision. That includes anyone taking insulin or another blood sugar medicine, since chromium may add to their effect. Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.\u003c\/p\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test. We test every incoming lot, the chromium polynicotinate and niacin in this capsule included, for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of G.T.F. Chromium has one.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA with globally sourced ingredients, in Mt. Angel, Oregon.\u003c\/strong\u003e That's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility sits right in it. The people who formulate, make and test these capsules work under one roof, and the owners work in the building too (owner-run since 2017). We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much chromium is in G.T.F. Chromium?\u003c\/h3\u003e\n\u003cp\u003eEach capsule has 200 mcg of chromium, from 2,000 mcg of chromium polynicotinate, plus 10 mg of niacin. That's 571% of the Daily Value for chromium and 62% for niacin. At the label's one capsule a day, a 60-capsule bottle lasts 60 days.\u003c\/p\u003e\n\u003ch3\u003eIs 571% of the Daily Value too much chromium?\u003c\/h3\u003e\n\u003cp\u003eFor most adults, no. The Food and Nutrition Board found no adverse effects linked to high chromium intakes from food or supplements, so it set no upper limit. The Daily Value (35 mcg) is a label reference, not a ceiling, and 200 mcg is a common amount in chromium research. The Board also noted that the data are limited and some caution is warranted, so stick to one capsule a day unless your practitioner says otherwise.\u003c\/p\u003e\n\u003ch3\u003eHow long before I notice a difference?\u003c\/h3\u003e\n\u003cp\u003eProbably never in a way you can feel. Chromium works in the background of normal metabolism, so it has no \"kick.\" Think of it as a steady daily habit, like a multivitamin, rather than something you wait to feel.†\u003c\/p\u003e\n\u003ch3\u003eWill the niacin make me flush?\u003c\/h3\u003e\n\u003cp\u003eIt's unlikely. Niacin flushing (warm, red, tingly skin) typically starts at 30 to 50 mg or more of nicotinic acid, and this capsule has 10 mg of niacin. Taking it with a meal, as directed, helps too.\u003c\/p\u003e\n\u003ch3\u003eCan I take it with Blood Sugar Support or a multivitamin?\u003c\/h3\u003e\n\u003cp\u003eOften yes, but add up the chromium and niacin first. \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/blood-sugar-support-60ct-caps\"\u003eBlood Sugar Support\u003c\/a\u003e has 75 mcg of chromium per two-capsule serving, and our \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-multi-vitamin-60-capsules\"\u003eMen's Multi\u003c\/a\u003e, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-multi-cap-60ct\"\u003eWomen's Multi\u003c\/a\u003e, \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/mens-50-plus-multivitamin\"\u003eMen's 50+\u003c\/a\u003e and \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/womens-50-plus-multivitamin\"\u003eWomen's 50+\u003c\/a\u003e each have 120 mcg per serving. Stacking them can push your chromium past 300 mcg a day, so run the combination by your healthcare practitioner.\u003c\/p\u003e\n\u003ch3\u003eIs G.T.F. Chromium vegetarian?\u003c\/h3\u003e\n\u003cp\u003eNo. The capsule shell is gelatin, as the other ingredients list shows. The label also states no soy, salt, yeast, gluten, milk \u0026amp; egg products, sugar, starch, or preservatives.\u003c\/p\u003e\n\u003ch3\u003eIs it safe to take with medication?\u003c\/h3\u003e\n\u003cp\u003eAsk your healthcare practitioner first. Chromium may add to the effect of insulin and other blood sugar medicines, and the NIH reports a small study in which chromium picolinate taken at the same time as levothyroxine, a thyroid medicine, cut how much of the medicine was absorbed. Our \u003ca href=\"https:\/\/learn.mtangelvitamins.com\/tools\/interaction-checker\"\u003esupplement and medication interaction checker\u003c\/a\u003e is a good place to start that conversation.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/blood-sugar-support-60ct-caps\"\u003eBlood Sugar Support\u003c\/a\u003e, the companion formula with psyllium husk, apple cider vinegar and berberine\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/blog\/new\/our-approach-to-raw-material-sourcing-and-testing\"\u003eHow we source and test raw materials\u003c\/a\u003e, from our Director of Quality and Compliance\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/learn.mtangelvitamins.com\/tools\/interaction-checker\"\u003eCheck supplement and medication interactions\u003c\/a\u003e before you add something to your routine\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eKozlovsky AS et al. Effects of diets high in simple sugars on urinary chromium losses. Metabolism. 1986. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3713513\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eVincent JB. The biochemistry of chromium. J Nutr. 2000. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10736319\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eVincent JB et al. Chromium. Adv Nutr. 2018. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30032219\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAmato P et al. Effects of chromium picolinate supplementation on insulin sensitivity, serum lipids, and body composition in healthy, nonobese, older men and women. J Gerontol A Biol Sci Med Sci. 2000. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10819315\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eNIH Office of Dietary Supplements. Chromium: Health Professional Fact Sheet. \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Chromium-HealthProfessional\/\"\u003eNIH ODS\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eNIH Office of Dietary Supplements. Niacin: Health Professional Fact Sheet. \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\"\u003eNIH ODS\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"60","offer_id":51571033211162,"sku":"015-M0710","price":13.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M0710REV00_ListingImage1.png?v=1768259725"},{"product_id":"mt-angel-vitamins-blood-pressure-ultra-support-4-pathway-circulatory-support-60-capsules","title":"Blood Pressure Ultra Support – 4-Pathway Circulatory Support | 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eBlood Pressure Ultra Support is a 60-capsule dietary supplement that puts four ingredients in each 2-capsule serving: 112 mg AmealPeptide® hydrolyzed casein (providing 7.5 mg of the milk peptides VPP and IPP), 350 mg citrulline, 227 mg celery seed extract and 20 mg snake root extract, plus 49.5 mg potassium. It supports healthy blood pressure levels already within the normal range.†\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis formula is for adults whose blood pressure is already in the normal range and who want to support it from more than one direction.† Circulation is easy to ignore in your 30s and 40s, which is exactly when a steady routine of food, movement and sleep starts paying off. Aging isn't optional. Getting old is.\u003c\/p\u003e\n\u003cp\u003eIt's also a formula with real rules. Snake root is a serious botanical, so this label carries strong warnings. Read them before you buy.\u003c\/p\u003e\n\u003ch2\u003eWhy people take Blood Pressure Ultra Support\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHealthy blood pressure.\u003c\/strong\u003e Supports healthy blood pressure levels already within the normal range.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNitric oxide.\u003c\/strong\u003e Citrulline helps your body make nitric oxide, the signal that helps vessel walls relax.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFlexible arteries.\u003c\/strong\u003e Milk-derived lactotripeptides support healthy arterial flexibility.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCalm vessel tone.\u003c\/strong\u003e Snake root supports the nervous system's normal role in resting vessel tone.†\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFluid balance.\u003c\/strong\u003e Celery seed extract and potassium support normal fluid balance.†\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat's in each serving\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eAmount per serving\u003c\/th\u003e\n\u003cth\u003e% Daily Value\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePotassium (from potassium citrate)\u003c\/td\u003e\n\u003ctd\u003e49.5 mg\u003c\/td\u003e\n\u003ctd\u003e1%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAmealPeptide® Hydrolyzed Casein (from milk) (providing 7.5 mg of valyl-prolyl-proline and isoleucyl-prolyl-proline)\u003c\/td\u003e\n\u003ctd\u003e112 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCitrulline (from citrulline malate)\u003c\/td\u003e\n\u003ctd\u003e350 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCelery Seed Extract (\u003cem\u003eApium graveolens\u003c\/em\u003e, contains 8.8% volatile oils)\u003c\/td\u003e\n\u003ctd\u003e227 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSnake Root Extract (\u003cem\u003eRauwolfia spp.\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e20 mg\u003c\/td\u003e\n\u003ctd\u003e*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Daily Value not established. Serving size: 2 vegetarian capsules. Servings per container: 30. Other ingredients: Cellulose (from capsule shell), organic rice extract, L-leucine, and silica. Label statement: \"Contains: Milk (casein).\" The label adds that anyone who can't have milk should not take this product. The front label carries gluten-free and soy-free icons. AmealPeptide® is a registered trademark of Calpis Co., Ltd.\u003c\/p\u003e\n\u003ch2\u003eHow Blood Pressure Ultra Support works\u003c\/h2\u003e\n\u003cp\u003eFour small levers instead of one big one: vessel-tone peptides, a nitric oxide building block, nervous system tone and fluid balance.\u003c\/p\u003e\n\u003ch3\u003eAmealPeptide® hydrolyzed casein (112 mg)\u003c\/h3\u003e\n\u003cp\u003eAmealPeptide is hydrolyzed casein: casein, the main protein in milk, broken down into small pieces. The pieces that matter are two tripeptides, each three amino acids long: valyl-prolyl-proline (VPP) and isoleucyl-prolyl-proline (IPP). Each serving provides 7.5 mg of the pair, printed on the panel.\u003c\/p\u003e\n\u003cp\u003eIn test tubes, VPP and IPP weakly slow ACE, an enzyme in the renin-angiotensin system, the hormone loop your body uses to set how tightly blood vessels squeeze. Whether that happens inside people is less clear. When 12 healthy men drank fermented milk containing these peptides every day for a week, \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19506528\/\"\u003eresearchers found no measurable ACE blocking in their blood\u003c\/a\u003e, and blood IPP rose only slightly and briefly. What has shown up in people is a change in the arteries themselves. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19783777\/\"\u003ean 8-week trial in 55 postmenopausal women aged 50 to 65\u003c\/a\u003e, lactotripeptides improved the flexibility (compliance) of the carotid artery while the placebo group didn't change, and pairing the peptides with moderate aerobic exercise produced the biggest gain, about 19%.† Translation: the peptides look like a teammate for your walking shoes, not a replacement.\u003c\/p\u003e\n\u003ch3\u003eCitrulline (350 mg, from citrulline malate)\u003c\/h3\u003e\n\u003cp\u003eCitrulline is an amino acid named for the watermelon (\u003cem\u003eCitrullus\u003c\/em\u003e). Your body converts it to arginine, which the cells lining your blood vessels use to make nitric oxide, the signal that tells vessel walls to relax.† Why not just take arginine? Swallowed arginine is largely broken down in the gut, while citrulline is readily absorbed. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17662090\/\"\u003ea randomized crossover trial in 20 healthy volunteers\u003c\/a\u003e, oral citrulline raised blood arginine more effectively than arginine itself, and the highest dose raised markers of nitric oxide activity, though no dose improved a standard test of vessel widening. In \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21067832\/\"\u003ea 7-day trial in 15 healthy men around age 58\u003c\/a\u003e, 5.6 g of citrulline a day lowered a measure of arterial stiffness compared with placebo, with no difference in blood pressure between the groups.\u003c\/p\u003e\n\u003cp\u003eCandidly, the nitric oxide and artery results above came at 5.6 to 6 grams a day, and this formula gives 350 mg per serving, so citrulline is a supporting player here, not the headliner. The malate form pairs it with malic acid, the compound that makes apples tart.\u003c\/p\u003e\n\u003ch3\u003eSnake root extract (20 mg)\u003c\/h3\u003e\n\u003cp\u003eSnake root is a small flowering shrub from India and Southeast Asia, used for centuries in Ayurvedic tradition. The Supplement Facts panel lists it as \u003cem\u003eRauwolfia spp.\u003c\/em\u003e, and the front label names \u003cem\u003eRauwolfia serpentina\u003c\/em\u003e. Its root holds a family of alkaloids, the best known being reserpine. These compounds act on the sympathetic nervous system, the \"fight or flight\" wiring that helps set how tense or relaxed your blood vessels are at rest.†\u003c\/p\u003e\n\u003cp\u003eThose same alkaloids are why this label carries its strongest warnings (see below). Most human research on snake root was done in people under medical care, not healthy adults, so we don't cite it here.\u003c\/p\u003e\n\u003ch3\u003eCelery seed extract (227 mg) and potassium (49.5 mg)\u003c\/h3\u003e\n\u003cp\u003eThe extract contains 8.8% volatile oils, about 20 mg per serving. Those oils carry phthalides such as 3-n-butylphthalide, the compounds behind celery's smell, and celery seed has a long traditional use for supporting normal fluid balance.† Most human research on celery seed was run in people under medical care rather than healthy adults, so we don't cite it here.\u003c\/p\u003e\n\u003cp\u003ePotassium works alongside sodium to manage the fluid inside and outside your cells.† At 49.5 mg per serving, 1% of the 4,700 mg Daily Value, it's a small top-up rather than a real source. A medium banana has about 422 mg, according to the \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Potassium-HealthProfessional\/\"\u003eNIH fact sheet on potassium\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eHow to take Blood Pressure Ultra Support\u003c\/h2\u003e\n\u003cp\u003eDirections, exactly as printed on the label: \"Take two capsules twice daily, morning and evening following a meal, as a dietary supplement.\"\u003c\/p\u003e\n\u003cp\u003eRight after breakfast and right after dinner is the easiest way to remember both. If you take any medication, bring the bottle to your pharmacist too: they can check every ingredient, snake root included, against your prescriptions.\u003c\/p\u003e\n\u003cp\u003eWarnings from the label:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNot for use by persons under 18.\u003c\/li\u003e\n\u003cli\u003eDo not use this product if you are pregnant or nursing.\u003c\/li\u003e\n\u003cli\u003eConsult your physician before use if you are taking any medications (especially blood pressure, heart, or psychiatric medications) or have a medical condition.\u003c\/li\u003e\n\u003cli\u003eDiscontinue use and consult your physician if you experience dizziness, lightheadedness, fatigue, mood changes, or gastrointestinal discomfort.\u003c\/li\u003e\n\u003cli\u003eDo not use if you have any history of depressed mood or other mental health conditions.\u003c\/li\u003e\n\u003cli\u003eContains milk (casein). If you can't have milk, don't take this product.\u003c\/li\u003e\n\u003cli\u003eKeep out of reach of children.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eDon't take our word for it\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVerified by independent labs.\u003c\/strong\u003e ISO 17025-accredited labs check our test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvery ingredient lot tested before use.\u003c\/strong\u003e Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf it misses spec, it doesn't go in a bottle.\u003c\/strong\u003e More than 99% of our tests pass, and the lots that don't are turned away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eA certificate of analysis for every lot.\u003c\/strong\u003e Every lot of Blood Pressure Ultra Support gets its own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMade in the USA, in Mt. Angel, Oregon.\u003c\/strong\u003e It's a farm town of about 3,500 people in the Willamette Valley, and this formula is made and tested there, from globally sourced ingredients, in our UL-certified cGMP facility. The people who formulate it, make it and test it work under one roof, and the owners work in the building too. We've been making supplements in Oregon since 1974, and we're not getting old either.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow do I take Blood Pressure Ultra Support?\u003c\/h3\u003e\n\u003cp\u003eTake two capsules twice daily, morning and evening, following a meal, as the label directs.\u003c\/p\u003e\n\u003ch3\u003eCan I take it if I'm on blood pressure or other medication?\u003c\/h3\u003e\n\u003cp\u003eTalk with your physician before you start. The label says to consult your physician before use if you take any medications, especially blood pressure, heart, or psychiatric medications, or if you have a medical condition.\u003c\/p\u003e\n\u003ch3\u003eWho should not take Blood Pressure Ultra Support?\u003c\/h3\u003e\n\u003cp\u003eSkip it if you're under 18, pregnant or nursing, have any history of depressed mood or other mental health conditions, or can't have milk (AmealPeptide® is hydrolyzed casein, a milk protein). Stop and call your physician if you notice dizziness, lightheadedness, fatigue, mood changes or stomach upset.\u003c\/p\u003e\n\u003ch3\u003eWhy AmealPeptide and citrulline instead of plain milk protein or arginine?\u003c\/h3\u003e\n\u003cp\u003eBecause each one delivers a specific, measured compound. AmealPeptide provides a printed 7.5 mg of the tripeptides VPP and IPP per serving, which plain milk protein doesn't spell out. And in a small trial in healthy volunteers, citrulline raised blood arginine more effectively than arginine itself.†\u003c\/p\u003e\n\u003ch3\u003eHow soon will I notice anything?\u003c\/h3\u003e\n\u003cp\u003eYou probably won't feel it. The changes in the studies above showed up over one to eight weeks and were measured with lab equipment, not by feel, so be consistent and keep your regular checkups.\u003c\/p\u003e\n\u003ch3\u003eWhat if snake root isn't right for me?\u003c\/h3\u003e\n\u003cp\u003eLook at \u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/yourheart-nutrients-heart-health\"\u003eYourHeart Nutrients, our circulation formula without snake root\u003c\/a\u003e, built around beta-sitosterol, CoQ10, L-citrulline malate and magnesium. Read its label too, and don't combine the two unless your practitioner says so, since both contain citrulline and potassium.\u003c\/p\u003e\n\u003ch2\u003eKeep learning\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/yourheart-nutrients-heart-health\"\u003eYourHeart Nutrients for circulation support without snake root\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/coq10-alpha-lipoic-acid\"\u003eCoQ10 100 mg with alpha lipoic acid for healthy heart function\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.mtangelvitamins.com\/products\/good-magnesium-chelate-amino-acids\"\u003eGood Magnesium, 200 mg of chelated magnesium for nervous system support\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eYoshizawa M et al. Additive beneficial effects of lactotripeptides and aerobic exercise on arterial compliance in postmenopausal women. Am J Physiol Heart Circ Physiol. 2009. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19783777\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eWuerzner G et al. The lactotripeptides isoleucine-proline-proline and valine-proline-proline do not inhibit the N-terminal or C-terminal angiotensin converting enzyme active sites in humans. J Hypertens. 2009. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19506528\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSchwedhelm E et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol. 2008. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17662090\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eOchiai M et al. Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men. Int J Cardiol. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21067832\/\"\u003ePubMed\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mt. Angel Vitamins","offers":[{"title":"Default Title","offer_id":51748416028954,"sku":"015-M7200","price":31.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1300\/7869\/files\/M7200REV01_ListingImage1.png?v=1772027690"}],"url":"https:\/\/www.mtangelvitamins.com\/collections\/targeted-support.oembed","provider":"Mt. Angel Vitamins","version":"1.0","type":"link"}