Rebuild Your Cells from the Inside Out.
Urolithin A activates mitophagy, the process that clears damaged mitochondria and replaces them with new ones. 500mg per capsule. The exact dose from published clinical trials.*
The Real Reason Your Energy Is Declining
You used to recover fast. Stay sharp all day. Power through a full schedule without that 3 PM wall. But over the last few years, something shifted. The sustained energy you took for granted started slipping away.
Here's what's actually happening: your mitochondria are breaking down. By your 40s, you're hauling around damaged, inefficient cellular power plants that drag down everything from muscle recovery to mental clarity. Your body has a built-in repair system for this called mitophagy. It slows down with age. Right when you need it most.
Urolithin A reactivates that repair system. It signals your body to clear out damaged mitochondria and generate fresh, efficient ones. Not a stimulant. Not a band-aid. Cellular maintenance your body should be doing on its own, but isn't.
Most People Can't Produce Urolithin A from Food
Your body needs specific gut bacteria to convert pomegranate compounds into Urolithin A. Most people don't have them.
Gut Conversion Capacity
Research shows only 30-40% of people have the specific gut bacteria needed to convert ellagitannins (from pomegranates) into Urolithin A. The rest produce little to none, regardless of diet.
Supplementation vs. Diet
Even among the 30-40% who can convert it, food sources deliver a fraction of the clinical dose. Supplementing directly delivers 500mg per capsule without depending on gut conversion.
From Dietary Precursors to Cellular Renewal
Activate Mitophagy
Triggers your cells' quality control system, tagging damaged mitochondria for removal. This is the housekeeping process that declines as you age.
Clear the Damage
Tagged mitochondria are broken down and recycled. The underperforming engines dragging down your cellular energy output are eliminated.
Rebuild Stronger
With the damage cleared, your cells generate new, efficient mitochondria. The result: improved cellular energy supporting muscle strength, endurance, and vitality.*
Single Ingredient. Full Dose. Nothing Hidden.
No proprietary blend. No fairy-dusted cocktail designed to look good on a label but deliver nothing in your body. One compound, fully disclosed, at the dose that the clinical studies actually used.
Matches published human trial dosing
Urolithin A is naturally derived from pomegranates and berries, but your gut has to convert it. Research shows most people lack the bacteria to produce meaningful amounts. Supplementing bypasses that bottleneck entirely.
Contains NO: soy, salt, yeast, gluten, wheat, milk, egg, sugar, starch, or preservatives.
Supplement Facts
Other Ingredients: Cellulose (from capsule shell), brown rice protein, vegetable stearates.
What People Are Saying
Three weeks in and the sustained energy throughout the day is real. No crash, no jitters. Just a steady baseline improvement. At 47, that matters.Mark T. // Verified Buyer
I train four days a week at 54. Recovery between sessions has noticeably improved since adding this. I respect the single-ingredient, full-dose approach.David R. // Verified Buyer
Researched Urolithin A for months before buying. Most brands underdose or hide behind blends. This is 500mg, period. The price reflects actual ingredient cost.Sarah L. // Verified Buyer
Individual results may vary. These testimonials reflect individual experiences and are not intended as guarantees.
What the Research Shows
Results from the ATLAS trial: 88 middle-aged adults, 4 months, randomized and placebo-controlled.*
Muscle Endurance Over Time
Percentage increase in skeletal muscle endurance (1000mg UA daily vs. placebo)
The Mitophagy Plateau
Activation follows a classic dose-response curve that asymptotes near 1000mg
The curve reaches ~82% activation at 500mg and ~100% at 1000mg. Beyond 1000mg, each additional 500mg adds 3 points or fewer. Our 500mg dose hits the optimal cost-to-benefit threshold.
Achieves ~82% peak mitophagy activation. Optimal cost-to-benefit ratio for long-term daily supplementation. Well within transporter capacity.
Reaches ~100% activation ceiling. Justified for targeted goals. Beyond this, additional UA provides negligible mitophagic benefit.
How This Stacks Up
| Mt. Angel Vitamins | Typical Competitor | |
|---|---|---|
| Urolithin A Dose | 500mg per capsule | 250mg or undisclosed |
| Formula Transparency | Single ingredient, fully disclosed | Proprietary blends |
| Third-Party Testing | Every batch | Often undisclosed |
| Manufacturing | cGMP, FDA-registered, Oregon | Varies widely |
| Supply Per Bottle | 60 days | Typically 30 days |
| Cost Per Day | $1.33 | $1.50 - $2.30 |
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Questions
Pomegranates contain precursor compounds called ellagitannins, but your gut bacteria have to convert them into Urolithin A. Research shows only 30-40% of people have the right microbiome to do this efficiently. Supplementing directly skips the conversion bottleneck and delivers the full 500mg clinical dose.
Cellular renewal is not instant. Some users report improved sustained energy within the first few weeks. The published clinical studies measured significant improvements after 2 to 4 months of daily use. One bottle is a 60-day supply for exactly this reason.
Urolithin A is one of the most expensive raw materials in supplements right now. The price difference between brands comes down to how much is in each capsule. We use 500mg (the clinical dose). Many competitors use 250mg or hide behind proprietary blends. You get 60 capsules (2-month supply), not 30. That's $1.33 per day.
Urolithin A is a naturally occurring postbiotic with a strong safety profile in published clinical trials. No serious adverse events have been reported. Consult your healthcare provider before use if pregnant, nursing, taking medications, or managing a medical condition.
Timeline's Mitopure is a well-known Urolithin A product and has funded much of the published research. Credit where it's due. Our differentiators: single-ingredient capsule at 500mg with no added blends, manufactured in our own cGMP facility in Oregon (not contract-packed), every batch tested in-house and by third parties. Transparency on sourcing and manufacturing at a competitive per-day cost.
Manufactured, bottled, and tested at Highland Laboratories in Mt. Angel, Oregon. FDA-registered, cGMP-certified, UL and NPA audited. We've been making supplements here for over 50 years.
Your Cells Won't Wait.
500mg clinical dose. Single ingredient. Made in Oregon for 50+ years. One capsule a day.
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