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The Only NMN on the Market Delivering Dual-Pathway Support.

We designed our advanced blend of NMN, NR, TMG, and Resveratrol with one clear goal: to be the most effective anti-aging product on the market. By combining multiple NAD⁺ precursors with methylation support and a highly recognized polyphenol, our formula addresses the key concerns of both educated consumers and health professionals.

INQUIRE ABOUT WHOLESALE
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bottle hero.png__PID:24be8508-2e84-4f56-aa0c-1938050a95c8

The Only NMN on the Market Delivering 
Dual-Pathway Support.

We designed our advanced blend of NMN, NR, TMG, and Resveratrol with one clear goal: to be the most effective anti-aging product on the market. By combining multiple NAD⁺ precursors with methylation support and a highly recognized polyphenol, our formula addresses the key concerns of both educated consumers and health professionals.

INQUIRE ABOUT WHOLESALE

Meet a Formula That's Truly Different.

Meet a Formula That's Truly Different.

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500 mg NMN - A direct NAD⁺ precursor with published studies showing rapid uptake and measurable increases in NAD⁺ levels.‡

200 mg NR - Nicotinamide Riboside complements NMN by providing a separate, validated pathway into the NAD⁺ salvage cycle.‡

50 mg TMG - Trimethylglycine provides essential methyl groups, supporting homocysteine metabolism and protecting against potential methyl donor depletion that can accompany NAD⁺ precursor supplementation.‡

250 mg Resveratrol - This polyphenol is studied for its ability to activate sirtuins, enhance mitochondrial efficiency, and complement NAD⁺ boosters in longevity science.‡

10 mg Bioperine®- This patented black pepper extract can increase nutrient absorption and bioavailability by inhibiting digestive enzymes and increasing thermogenesis‡

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500 mg NMN

A direct NAD⁺ precursor with published studies showing rapid uptake and measurable increases in NAD⁺ levels.‡

200 mg NR

Nicotinamide Riboside complements NMN by providing a separate, validated pathway into the NAD⁺ salvage cycle.‡

50 mg TMG

Trimethylglycine provides essential methyl groups, supporting homocysteine metabolism and protecting against potential methyl donor depletion that can accompany NAD⁺ precursor supplementation.‡

250 mg Resveratrol

This polyphenol is studied for its ability to activate sirtuins, enhance mitochondrial efficiency, and complement NAD⁺ boosters in longevity science.‡

10 mg Bioperine®

This patented black pepper extract can increase nutrient absorption and bioavailability by inhibiting digestive enzymes and increasing thermogenesis‡

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Made in the U.S.A.

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Gluten-Free

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Non-GMO

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Dairy-Free

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Soy-Free

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Made in
the U.S.A.

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Gluten
Free

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Non-GMO

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Dairy-Free

Science-Backed Innovation That is a Step Ahead.

The Distinct Advantage of both NMN and NR

Where most NAD⁺ products rely on a single ingredient, this formula leverages two distinct precursors: NMN and NR. Human clinical research has confirmed their ability to raise NAD⁺ levels. A 2023 randomized controlled trial reported that “oral NMN supplementation significantly increased blood NAD⁺ concentrations vs. placebo at both 30 and 60 days”( web†pubmed.ncbi.nlm.nih.gov/36482258】. Meanwhile, trials on NR demonstrate that it “markedly increases NAD⁺ metabolome in blood while maintaining a strong safety profile, even at high doses”【web†nature.com/articles/s41467-023-43514-6】. Together, NMN and NR deliver a dual-pathway approach that ensures more reliable and comprehensive NAD⁺ support—a critical differentiator in a crowded market.

The Inclusion of TMG

The inclusion of TMG (Trimethylglycine) adds another layer of sophistication. Research consistently shows that TMG “decreases plasma homocysteine concentrations by 5–20% depending on dose”【web†pmc.ncbi.nlm.nih.gov/articles/PMC3610948】. This is crucial, because NAD⁺ precursor metabolism can increase methylation demands, and TMG helps maintain balance by acting as a methyl donor. By addressing this biochemical interplay directly, the formula is designed not just for efficacy, but also for long-term metabolic safety.

Resveratrol Adds a Finishing Touch

Resveratrol rounds out the formula with broad cellular support. Resveratrol has been shown to activate sirtuins, with one study noting that it “stabilizes SIRT1-peptide interactions, enhancing mitochondrial efficiency and DNA repair capacity”【web†nature.com/articles/srep38186】. Its long-standing recognition in the longevity space not only strengthens the scientific foundation of the formula but also provides instant consumer familiarity, making merchandising easier for retailers.

SELL NMN + NR WITH TMG AND RESVERATROL

Two On Ramps, One Destination: More Reliable NAD+ Elevation

Combining NMN + NR offers broader coverage than using either alone

NMN TO NAD+

  • NMN enters directly into the salvage pathway
  • Quickly converts to NAD⁺ in cells
  • Human trials show NAD⁺ levels rise in just weeks

NR TO NAD+

  • NR takes a separate entry point via nicotinamide riboside kinase
  • Converted into NMN, then into NAD⁺
  • Clinical studies confirm NR “markedly increases the NAD⁺ metabolome”

Two On Ramps, One Destination: More Reliable NAD+ Elevation

Combining NMN + NR offers broader coverage than using either alone

NMN TO NAD+

  • NMN enters directly into the salvage pathway
  • Quickly converts to NAD⁺ in cells
  • Human trials show NAD⁺ levels rise in just weeks

NR TO NAD+

  • NR takes a separate entry point via nicotinamide riboside kinase
  • Converted into NMN, then into NAD⁺
  • Clinical studies confirm NR “markedly increases the NAD⁺ metabolome”

Our NMN + NR is Leading the NAD+ Trend.

Our NMN + NR is Leading the NAD+ Trend.

Brand

Product

Format

Key Actives

Dual Pathway (NMN & NR)

Methylation Support

Added Resveratrol

Mt. Angel Vitamins

NMN + NR with TMG and Resveratrol

NMN, NR Combo

NMN, NR, TMG, Resveratrol

ChromaDex

Tru Niagen 300 mg

NR Only

NR Only

ChromaDex

Tru Niagen PRO 1000 mg

NR Only

NR Only

Elysium Health

Elysium Basis

NR Combo

NR, Pterostilbene

Thorne

Thorne ResveraCel

NR Combo

NR, Quercetin, Resveratrol, Betaine

Designs for Health

Designs for Health Liposomal NMN Synergy

NMN Combo

NMN, TMG

Wonderfeel

Wonderfeel Youngr NMN

NMN Combo

NMN, Resveratrol, Ergothioneine

ProHealth Longevity

ProHealth NMN Pro 300

NMN Only

NMN

Renue by Science

Renue by Science LIPO NMN

NMN Only

NMN

Life Extension

Life Extension NAD+ Cell Regenerator

NR Only

NR

Built from Research and Ready for Market.

The NAD⁺ category is one of the fastest-growing supplement segments, fueled by ongoing clinical research and significant consumer interest in healthy aging. This formula combines trending ingredients with a design that commands trust and higher price points. It is positioned as both an upsell and a destination product: one that draws in health-savvy shoppers and reinforces a retailer’s credibility in the advanced nutrition space. 

Because it integrates multiple scientifically validated pathways, this product is easy to recommend, easy to merchandise, and easy to differentiate. It has broad cross-category relevance—from longevity and cellular energy to metabolic health and cognitive support—allowing for flexible placement in-store and online.

ORDER MT. ANGEL VITAMINS' NMN + NR
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References

  • Yi L, et al. The efficacy and safety of β-nicotinamide mononucleotide supplementation in healthy middle-aged and older adults: A randomized, multicenter, double-blind, placebo-controlled study. Front Aging Neurosci. 2023. PubMed link
  • Igarashi M, et al. Chronic nicotinamide mononucleotide supplementation improves muscle performance in older adults. GeroScience. 2022. PMC link
  • Conze D, et al. Nicotinamide riboside supplementation increases NAD⁺ metabolome in humans. Nature Communications. 2023. Nature link
  • McRae MP. Betaine supplementation decreases plasma homocysteine in healthy adult subjects: A meta-analysis. J Clin Nutr. 2013. PMC link
  • Hou X, et al. Resveratrol serves as a protein-substrate interaction stabilizer for SIRT1 activation. Scientific Reports. 2016. Nature link

‡These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.