Buyer’s guide
Best NMN supplement: how to choose with confidence
Quick answer
The best NMN supplements are simple, tested capsule formulas that publish recent Certificates of Analysis, match label potency, and avoid hype. Look for β‑NMN in a sealed bottle with a desiccant, clean excipients, and a serving size that mirrors human trials - typically 250 to 600 mg daily for 8 to 12 weeks. If a product hides behind a proprietary blend or lacks a current COA, skip it.
What matters most
| Criterion | What to look for | Why it matters |
|---|---|---|
| Identity and potency | β‑NMN listed clearly; recent COA confirming identity by HPLC or LC‑MS and potency within ±10% | Confirms you are buying the right ingredient at the stated dose |
| Purity and contaminants | Heavy metals, micro, and residual solvents tested; results meet strict limits | Protects against impurities that shouldn’t be in your bottle |
| Packaging and stability | Opaque or amber bottle, foil seal, desiccant, tight closure | NMN is sensitive to moisture; good packaging helps maintain potency |
| Transparent labeling | Clear amount of NMN per capsule; no proprietary blends for actives | Lets you match study‑like intakes without guesswork |
| cGMP + third‑party testing | Manufactured in a cGMP facility with third‑party lab verification | Raises confidence in quality and data integrity |
| Price per 100 mg | Calculate: price ÷ (total mg per bottle ÷ 100) | Gives a fair, apples‑to‑apples value metric |
| Claims and compliance | No disease claims; research‑backed language; lot‑specific COAs available on request | Signals a responsible brand that respects regulations |
Simple scoring rubric you can apply
Score each product 0 to 5 on these, then weight as shown.
| Category | Weight | Notes |
|---|---|---|
| Identity + potency COA | 25% | Recent, method listed, batch‑matched |
| Purity panels (metals, micro, solvents) | 25% | Third‑party lab, clear limits |
| Stability + packaging | 15% | Desiccant, seal, opaque bottle |
| Label accuracy + no blends | 15% | Per‑capsule mg listed, nothing hidden |
| Value per 100 mg | 10% | Use the formula above |
| Transparency and access to COAs | 10% | Public COA or on request within 1 business day |
Why we favor capsules for most people
- Most human trials that raised blood NAD+ used oral dosing with simple capsules
- Accurate per‑capsule dosing makes it easy to match study ranges
- Sealed packaging with desiccant resists moisture and protects potency
- Daily adherence is easier than measuring loose powder or waiting on sublinguals
For pros and cons of each form, see sublingual vs capsule vs powder.
Serving size that makes sense
Match what human trials commonly used and reassess after one cycle.
- Typical study ranges: 250 to 600 mg per day for 8 to 12 weeks
- Some studies used 900 mg per day; a short safety study tested 1250 mg per day for 4 weeks
- Start at the low end if you are new to NMN, then adjust only if needed and tolerated
Read the full NMN dosage guide and safety notes before you begin.
Red flags - skip these instantly
- No recent COA or vague “tested for quality” language
- Proprietary blends that hide how much NMN you get per serving
- Outlandish claims like reversing aging or treating disease
- See‑through baggies, no desiccant, or poor packaging for a moisture‑sensitive ingredient
- Impossible value claims compared to market price per 100 mg
Our recommended format: Mt. Angel Vitamins NMN+NR Capsules
If you prefer a simple, study‑like approach, a clean capsule with published COAs is the straightforward choice. We prioritize cGMP manufacturing, third‑party testing, transparent labeling, sealed bottles with desiccant, and evidence‑aligned serving sizes. That is exactly how we build our capsule formulas.
Pros
- Accurate per‑capsule dosing aligned to study ranges
- Sealed bottle with desiccant for stability
- COAs available and lot‑matched
- Clean excipients, no proprietary blends
Considerations
- Capsules cost more per mg than bulk powder
- If you dislike swallowing capsules, consider sublingual or split dosing
Safety and compliance
Human studies generally report good short‑term tolerability at 250 to 900 mg daily for 8 to 12 weeks, with a 4‑week safety study at 1250 mg daily. Long‑term data are limited. Do not use if you are pregnant or nursing, under 18, or on prescription medications that affect blood sugar or blood pressure without talking to your clinician. Remember that in 2025 FDA clarified NMN is not excluded from the dietary supplement definition - standard rules still apply. This page is educational, not medical advice.
FAQ
- How do I verify a COA
- Check that the COA lists the same lot number as your bottle, shows test methods like HPLC or LC‑MS for identity, and includes contamination panels. Look for a third‑party lab name and date.
- Is sublingual better than capsules
- Direct head‑to‑head human data are limited. Oral capsules have strong human evidence for raising blood NAD+. Choose what you can take consistently.
- What is a fair price per 100 mg
- Use the formula: price ÷ (total mg per bottle ÷ 100). Compare across similar quality levels and recent COAs.
- Is NMN legal in the U.S.
- Yes. FDA concluded in late September 2025 that NMN is not excluded from the dietary supplement definition. Normal supplement rules still apply. See legal status.
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