Your cells have a cleanup problem. This fixes it.
Two clinically-studied compounds. One complete mitochondrial renewal system. The stack your 40-year-old body actually needs.
See Bundle Pricing →Two problems. Two solutions. One complete stack.
- Only compound with human RCT data showing it restores mitophagy
- 500 mg — the exact dose used in the Nature Metabolism 2019 trial
- Single-ingredient formula. Nothing else in the bottle.
- Activates PINK1/Parkin pathway — your cells' cleanup system
- NMN + NR hit the NAD+ pathway from two different angles
- Resveratrol activates the sirtuins that use NAD+
- TMG prevents the methylation drain high-dose NMN causes
- BioPerine® + Zinc for absorption and cofactor support
Save up to $70 when you buy both together · Free shipping · Made in Oregon since 1974
The Mitochondria Stack
Buy both together and save. Free shipping on every bundle. The more you stock up, the more you save — and the longer you stay consistent, which is when the results actually show up.
1 bottle NMN+NR (60 caps)
- 60-day supply of each product
- Free shipping (save ~$8)
- Total savings: ~$18
2 bottles NMN+NR (120 caps)
- 120-day supply of each product
- Free shipping (save ~$8)
- Best value per dose
- Total savings: ~$38
3 bottles NMN+NR (180 caps)
- 180-day supply of each product
- Free shipping (save ~$8)
- Maximum savings per bottle
- Total savings: ~$78
* Bundle pricing applied automatically at checkout with discount code. Free shipping on all bundle orders within the contiguous US.
This isn't theory. It's published data.
Both compounds in this stack have been studied in human clinical trials. Not rodent studies. Not in vitro. Actual humans, measured outcomes.
Urolithin A — Nature Metabolism 2019
61 adults randomized to 500 mg/day Urolithin A or placebo for 4 weeks. The treatment group showed significant increases in mitochondrial gene expression and improvements in muscle function markers. First human study to demonstrate that a dietary compound can activate mitophagy in vivo.
Amazentis SA, Lausanne, Switzerland. Ryu D, et al. Nature Metabolism 2019;1:595–603.
NMN — Cell Metabolism 2023
Randomized, double-blind, placebo-controlled trial in 80 middle-aged adults. 300 mg/day NMN supplementation for 60 days significantly increased blood NAD+ levels and improved muscle insulin sensitivity. Muscle function scores improved in the NMN group vs. placebo.
Igarashi M, et al. Cell Metabolism 2023;37(1):35–47.
NR — Nature Communications 2016
First human trial of nicotinamide riboside. Oral NR supplementation safely and sustainably increased NAD+ in blood by up to 2.7-fold. Dose-dependent response confirmed. Established NR as a viable NAD+ precursor in humans with a clean safety profile.
Trammell SA, et al. Nature Communications 2016;7:12948.
Mitophagy Decline After 40
Multiple studies confirm that mitophagic flux declines significantly with age in skeletal muscle and cardiac tissue. Accumulation of dysfunctional mitochondria is now recognized as a primary driver of age-related muscle weakness, fatigue, and metabolic dysfunction — independent of total mitochondrial mass.
Leduc-Gaudet JP, et al. Aging Cell 2015;14(6):1006–1023.
Simple protocol. Real results.
Morning with food
Take 1 capsule of Urolithin A and 1 capsule of NMN+NR with your first meal. Both are fat-soluble — food improves absorption. Consistent morning dosing keeps blood levels stable.
Give it 4–8 weeks
Mitophagy and NAD+ restoration are not overnight processes. Most people notice improved recovery and afternoon energy first, usually around weeks 3–4. Sleep quality improvements often follow by week 6–8.
Stay consistent
The research is clear: the benefits of both compounds are cumulative and require consistent supplementation. This is why the Double or Triple Stack makes sense — you don't want to run out mid-protocol.
We make this. We don't just sell it.
Every capsule in this stack is formulated and manufactured in our own facility in Mt. Angel, Oregon — the same building we've operated since 1974. We run in-house analytical testing on every lot. We issue lot-specific Certificates of Analysis. We don't outsource quality control to a co-packer and hope for the best. When you buy from us, you're buying from the people who actually made it.
Frequently Asked
Pick your stack. Start the protocol.
The research is there. The products are made in our own facility. The only variable is whether you start today or keep waiting.
Let customers speak for us
I have been taking these for almost a month now and already feel healthier and have more energy. This vitamin in particular has everything we need for men in our 50’s. 60 pills per bottle 2 a day = 30 day supply for $56 to $57. I believe they are a bit pricy but well worth it
This supplement is exactly what I was looking for for my son. It tastes good and provides him with the nutrients we were looking for without synthetic ingredients. Great customer service as well. Thank you!
I have been using the blood sugar support for about two weeks now. I have been type two diabetic since 2018.
I have seen a noticeable decline in high blood sugars. With our hot weather this summer I did have some ice cream a couple days in a row and I noticed that my blood sugar still stayed within a healthy range. I can’t guarantee that for everyone, but it did help me.
I had multiple surgeries on my sinuses. I was told that I would have to be on steroids the rest of my life, as the surgeries did not correct the problem. Mt Angel Quercetin Nettle+ has completed cured all my sinus issues! I recommended it to all who struggle seasonal or otherwise.
