Adrenal Support – Adaptogens for Occasional Stress | 60 Vegetarian Tablets
Adrenal Support is a vegetarian tablet that combines a 425 mg herbal blend of rhodiola, ashwagandha, eleuthero, schisandra, wild yam and nettle with 500 mg of pantothenic acid (vitamin B5), 20 mg of vitamin B6 and 50 mg of vitamin C in every 2-tablet serving. Each bottle holds 60 tablets. It's made to support a healthy response to occasional stress.†
Your 30s and 40s are when the calendar fills up: work, kids, aging parents, and the 6 a.m. workout you swore you'd keep. It's also the right time to build the habits that carry you into your 70s and 80s. Aging isn't optional. Getting old is.
Adrenal Support is for adults who want one simple daily step for how their body handles everyday pressure, alongside sleep, food, movement and saying no to the fourth committee.†
Why people take Adrenal Support
- To support a healthy response to occasional stress, with four herbs researchers call adaptogens: rhodiola, ashwagandha, eleuthero and schisandra.†
- To support focus and mental performance on demanding days.†
- To support normal energy metabolism with 500 mg of pantothenic acid and 20 mg of vitamin B6.†
- To get vitamin C, a nutrient your adrenal glands hold in high concentration and use in normal hormone production.†
What's in each serving
| Ingredient | Amount per serving | % Daily Value |
|---|---|---|
| Vitamin C | 50 mg | 55% |
| Vitamin B6 (from pyridoxine HCl) | 20 mg | 1,176% |
| Pantothenic Acid (from d-calcium pantothenate) | 500 mg | 10,000% |
| Proprietary Herbal Blend: Rhodiola Root Extract (Rhodiola rosea, standardized to 1% salidrosides), Ashwagandha Root Extract (Withania somnifera, standardized to 2.5% withanolides), Wild Yam Root 10:1 Extract (Dioscorea spp.), Schizandra Berry (Schisandra chinensis), Eleutherococcus senticosus Root 50:1 Extract, and Stinging Nettle Leaf (Urtica dioica, organic, freeze-dried) | 425 mg | * Daily Value not established |
Serving size: 2 vegetarian tablets. Servings per container: 30. Other ingredients: Cellulose, L-leucine, silica, and chlorophyll. The label states: "NO soy, salt, yeast, gluten, milk & egg products, sugar, starch, or preservatives."
How Adrenal Support works
"Adaptogen" is what researchers call herbs studied for helping the body keep its balance under stress. A review of that research describes adaptogens as working through your main stress-response system (the hypothalamic-pituitary-adrenal, or HPA, axis) and stress messengers like cortisol and the protective protein Hsp70, with much of the mechanism work done in cells and animals (Panossian and Wikman's review of adaptogen mechanisms).
One honest note: the six herbs come as a 425 mg proprietary blend, so the label doesn't list how much of each herb is in a serving. That means we can't tell you this tablet matches the doses used in the studies below, and we won't pretend it does.
Rhodiola root extract (standardized to 1% salidrosides)
Salidroside is one of the compounds rhodiola extracts are standardized to, and "standardized to 1%" means each lot of extract is checked to carry that level. A systematic review of 11 placebo-controlled trials (six on physical performance, four on mental performance) concluded rhodiola may help both, with only a few mild side effects, but noted that most findings hadn't been independently repeated (a systematic review of rhodiola trials).†
Ashwagandha root extract (standardized to 2.5% withanolides)
Ashwagandha is an herb with a long history of traditional use, and this blend uses an extract of its root. Withanolides are the compounds its extracts are measured by, and ours carries 2.5%. In a 60-day trial, 60 healthy adults who reported high stress took 240 mg of a standardized ashwagandha extract or a placebo once a day. The ashwagandha group had a larger drop in morning cortisol than the placebo group, and no side effects were reported. It was a small study, and the authors called for larger ones (a 60-day ashwagandha trial in stressed, healthy adults).†
Eleuthero and schisandra
Our eleuthero (Eleutherococcus senticosus) is a 50:1 root extract, made from roughly 50 parts root concentrated into 1 part extract. The schisandra is listed on the label as the berry itself (Schisandra chinensis). Researchers often study these two with rhodiola as a trio. In a pilot trial, 40 healthy women who said they'd felt stressed for a long time took a single 270 mg tablet of a fixed rhodiola, schisandra and eleuthero combination or a placebo. Two hours later, the combination group scored better on attention, speed and accuracy during a demanding mental task (a single-dose trial of a rhodiola, schisandra and eleuthero blend). That was one dose of a different product, so read it as a promising signal, not a promise.†
Pantothenic acid (vitamin B5), 500 mg
Your body uses pantothenic acid to make coenzyme A, a molecule needed to build and break down fats and for many other reactions in your cells. Ours is d-calcium pantothenate, a common supplemental form (NIH fact sheet on pantothenic acid). The Daily Value is 5 mg, which is why 500 mg reads as 10,000%.†
Vitamin B6, 20 mg
This is pyridoxine HCl, the most common form of B6 in supplements. In your body, B6 works through its active coenzyme forms (PLP and PMP), which take part in more than 100 enzyme reactions, mostly in protein metabolism, and B6 also helps make neurotransmitters (NIH fact sheet on vitamin B6). Twenty milligrams is 1,176% of the Daily Value and under the 100 mg a day upper limit the U.S. Food and Nutrition Board set for adults.†
Vitamin C, 50 mg
Your adrenal glands hold some of the highest vitamin C levels in your body. Vitamin C is a cofactor for making the catecholamines (the adrenaline family) and for steroid hormone production in the adrenal glands, based mostly on cell and animal research (a review of vitamin C's role in the adrenal glands). Fifty milligrams is 55% of the Daily Value.†
Wild yam root and nettle leaf
Wild yam root (a 10:1 extract) and organic, freeze-dried stinging nettle leaf round out the blend as traditional herbs. Human research on either one for stress is thin, so we won't oversell them.
How to take Adrenal Support
The label says: "One to two tablets, as a dietary supplement." The amounts in the table above are for a 2-tablet serving.
The label doesn't call for food, so take it at a time you'll remember. Taking other supplements? Add up the vitamin B6 across all of them (see the FAQ).
Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition.
Don't take our word for it
- Verified by independent labs. ISO 17025-accredited labs check our test results.
- Every ingredient lot tested before use. Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.
- If it misses spec, it doesn't go in a bottle. More than 99% of our tests pass, and the lots that don't are turned away.
- A certificate of analysis for every lot. Each lot of Adrenal Support has its own.
Made in the USA. Made and tested in Mt. Angel, Oregon. It's a farm town of about 3,500 people in the Willamette Valley, and our UL-certified cGMP facility keeps the formulators, the makers and the testers under one roof. The company has been owner-run since 2017, and the owners work in the building. We've been making supplements in Oregon since 1974. That's 52 years, and we're not getting old either.
Frequently asked questions
How many Adrenal Support tablets should I take?
Follow the label: "One to two tablets, as a dietary supplement." The Supplement Facts amounts are for 2 tablets, and the bottle holds 60 tablets, or 30 servings.
Does Adrenal Support contain caffeine?
No, caffeine isn't on the label. Each serving is three vitamins, the six-herb blend, and four other ingredients: cellulose, L-leucine, silica and chlorophyll.
Isn't 10,000% of the Daily Value of pantothenic acid a lot?
It's a big percentage on a small baseline. The Daily Value is just 5 mg. No upper limit has been set because there are no reports of pantothenic acid toxicity in humans, and the mild stomach upset reported with very large doses came at around 10 grams a day, twenty times the 500 mg in a serving.
Can I take Adrenal Support with your B-Complex?
Check with your practitioner first, because of vitamin B6. A serving of Adrenal Support has 20 mg and a capsule of our B-Complex vitamin formula has 100 mg, which adds up to 120 mg a day. The U.S. upper limit for adults from all sources is 100 mg a day. Our B-12 Essential Trio liquid adds 4 mg of B6 per serving.
Can I take it with CortiResponse?
Ask your practitioner before combining them. Both contain ashwagandha (CortiResponse, our ashwagandha and L-theanine formula, lists 100 mg of ashwagandha root per serving), and one may be enough.
How long until I notice anything?
We can't promise a timeline. The three-herb trial above measured results two hours after one dose, and the ashwagandha trial after 60 days, both with different products at known doses.
Is Adrenal Support safe with my medication?
Ask your healthcare practitioner, and bring the bottle. Herbs aren't harmless just because they grow in the ground. You can also look up combinations in our supplement and medication interaction checker first.
Keep learning
- What "Single Bottle Solution" on our label means
- Sleepy Sleep, an herbal formula for the evening half of your routine
References
- Panossian A et al. Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress-Protective Activity. Pharmaceuticals (Basel). 2010. PubMed
- Hung SK et al. The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials. Phytomedicine. 2011. PubMed
- Lopresti AL et al. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019. PubMed
- Aslanyan G et al. Double-blind, placebo-controlled, randomised study of single dose effects of ADAPT-232 on cognitive functions. Phytomedicine. 2010. PubMed
- Patak P et al. Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla. Endocr Res. 2004. PubMed
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
