Inflameze Advanced – Turmeric Joint Comfort Support | 60 Vegetarian Capsules
Inflameze Advanced is a turmeric-based joint comfort supplement with 250 mg of Curcumin Complex from CurcuWIN™ in every 1-capsule serving, plus a 305 mg blend of boswellia standardized to 70% boswellic acids, bromelain, green tea extract, ginger root extract and Bioperine™ (a black pepper extract). Each bottle holds 60 vegetarian capsules. It supports joint comfort.†
Inflameze Advanced is for people who want their knees, hips and shoulders to keep up with their plans: the 42-year-old training for a half marathon, the 50-something who still carries the canoe to the river.
Aging isn't optional. Getting old is. Joints are often where people first feel the years, and the habits that help most (strength work, walking, sleep, decent food) pay off when you start in your 30s and 40s. It's one small, steady part of that routine, not a stand-in for it.
Why people take Inflameze Advanced
- Supports joint comfort, with 250 mg of curcumin complex from CurcuWIN in every capsule.†
- Uses CurcuWIN, a curcumin form made to dissolve in water, so more curcumin reaches the bloodstream than from standard, unformulated curcumin extract.†
- Pairs curcumin with boswellia standardized to 70% boswellic acids and bromelain from pineapple.†
- Provides antioxidant polyphenols from turmeric and green tea extract.†
What's in each serving
| Ingredient | Amount per serving | % Daily Value |
|---|---|---|
| Curcumin Complex (from CurcuWIN™) | 250 mg | Not established |
| Proprietary Blend, containing: Boswellia serrata Standardized Extract (Standardized to 70% Boswellic Acids), Bromelain (from pineapple, Ananas comosus), Green Tea Standardized Extract (Standardized to 50% polyphenols, 35% catechins, and 15% EGCG), Ginger Root 4:1 Extract, and Bioperine™ | 305 mg (whole blend) | Not established |
Serving size: 1 vegetarian capsule. Each bottle holds 60 capsules, so 60 one-capsule servings. Other ingredients: Vegetable cellulose (preservative-free, from capsule shell), organic rice concentrate, and organic rice extract. The label states: "NO corn, soy, salt, yeast, gluten, milk & egg products, sugar, starch, or preservatives." It also states: "This product does not contain genetically modified materials."
How Inflameze Advanced works
Straight talk first: the research below tests single ingredients or pairs, not Inflameze Advanced itself, usually in other forms and amounts. The 305 mg blend is listed as one total, so we don't guess at individual amounts.
Curcumin Complex from CurcuWIN: 250 mg
Curcumin is the yellow-orange compound in turmeric root. Its weak spot is plumbing: it barely dissolves in water, so most of a standard curcumin extract passes straight through. CurcuWIN disperses curcumin on a water-soluble carrier with cellulose derivatives, plus antioxidants that help keep it from breaking down, so more of it dissolves in the watery gut where it can be absorbed.
In a crossover study in 12 healthy young adults, a formulation built that way, supplied by OmniActive (the CurcuWIN trademark owner), put 45.9 times more total curcuminoids into the blood over 12 hours than a standard, unformulated curcumin extract, milligram for milligram of curcuminoids. The limits: one dose, 12 people averaging 23 years old (11 of them men), and blood levels rather than how anyone felt. Turmeric extract was 20 to 28% of that formulation, the rest being carrier, cellulose derivatives and antioxidants; our label lists 250 mg of the whole complex, without a separate curcuminoid figure.
On results, an umbrella review of meta-analyses of randomized trials rated curcumin's effect on muscle soreness after muscle-damaging exercise as moderate-certainty evidence, across many curcumin forms and doses.† The closest test of this ingredient is smaller and more mixed. In an 8-week placebo-controlled trial of CurcuWIN in 63 active young adults, people took 250 mg or 1,000 mg of CurcuWIN a day (50 or 200 mg of curcuminoids in that study). By weight, that's the Curcumin Complex in one or four Inflameze Advanced capsules. After a downhill run, the 1,000 mg dose limited the drop in some, but not all, strength measures compared with placebo, though its lower soreness scores didn't reach statistical significance. The 250 mg dose showed no advantage. Background, not a promise for this capsule.
Boswellia serrata extract, standardized to 70% boswellic acids
Boswellia serrata, sometimes called Indian frankincense, is a tree native to India, and its gum resin is the source of boswellic acids. "Standardized to 70%" means the extract is made to contain that share of boswellic acids, the resin's signature compounds.
In a crossover study in healthy men, taking a different boswellia extract (786 mg) with a high-fat meal raised blood levels of several boswellic acids several-fold compared with an empty stomach. That's why we suggest taking Inflameze Advanced with a meal. And in a 12-week randomized trial in 47 healthy male cyclists averaging 46 years old, adding a curcumin and boswellia tablet to a Mediterranean diet cut advanced glycation end products (markers tied to oxidative stress) about 42%, while diet alone didn't.† The limits: a small pilot study with no placebo, a different curcumin form and amount, and blood markers aren't how your knees feel.
Bioperine (black pepper extract)
Bioperine is a black pepper extract whose active compound, piperine, slows one of the chemical tagging steps the gut wall and liver use to clear curcumin. In a study in healthy volunteers, 2 grams of plain curcumin alone left blood levels undetectable or very low, while adding 20 mg of piperine raised curcumin's bioavailability by 2,000%. That study used plain curcumin, not CurcuWIN, and we haven't found one testing the two together. They work on different steps: CurcuWIN helps curcumin dissolve, and piperine slows its clearance.
Bromelain, green tea and ginger
Bromelain is a group of protein-digesting enzymes from pineapple, long paired with boswellia and turmeric in joint formulas, including our original Inflameze. The label gives no enzyme activity rating, so we don't quote one.
The green tea extract is standardized to 50% polyphenols, 35% catechins and 15% EGCG, and those polyphenols are antioxidants.† The label doesn't list caffeine or say whether the extract is decaffeinated, so if you're sensitive, take your second dose with an early dinner.
Ginger is the familiar kitchen root, and "4:1" means four parts ginger root were concentrated into one part extract. Its individual amount in the blend isn't listed, so we make no specific claim for it.
How to take Inflameze Advanced
The label directions: "One to two capsules twice daily, as a dietary supplement." That's 2 to 4 capsules a day. Our suggestion: start with one capsule at breakfast and one at dinner.
Ask your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. If you take prescription medication, including blood thinners, show your practitioner or pharmacist the Supplement Facts panel before you start.
Don't take our word for it
We've been making supplements in Oregon since 1974. Here's what stands behind every bottle of Inflameze Advanced.
- Verified by independent labs. ISO 17025-accredited labs check our test results.
- Every ingredient lot tested before use. Federal rules only require an identity test on incoming dietary ingredients. We test every incoming lot for identity, potency, heavy metals and microbes.
- If it misses spec, it doesn't go in a bottle. More than 99% of our tests pass, and the lots that don't are turned away.
- A certificate of analysis for every lot. Every lot of Inflameze Advanced has its own.
Made in the USA. Made and tested in Mt. Angel, Oregon. Mt. Angel is a farm town of about 3,500 people in the Willamette Valley. Our UL-certified cGMP facility there keeps formulators, makers and testers under one roof, and the owners work in the building too. We've been making supplements for 52 years, and we're not getting old either.
Frequently asked questions
How many Inflameze Advanced capsules should I take a day?
Per the label, one to two capsules twice daily (2 to 4 a day). Two capsules give you 500 mg of Curcumin Complex from CurcuWIN and 610 mg of the blend; four give you 1,000 mg and 1,220 mg. A 60-capsule bottle lasts 30 days at two a day or 15 days at four.
Should I take Inflameze Advanced with food?
We suggest it. The label doesn't require food, but boswellic acids absorbed several-fold better with a high-fat meal in the study above.
How long before I notice a difference?
There's no set timeline, and we won't make one up. The longer studies above ran 8 to 12 weeks, so take it steadily at the label's dose and judge it by your normal week: the run, the yard work, the stairs.†
Which Inflameze is right for me?
The original Inflameze spreads each capsule across seven ingredients, including 50 mg of Curcumin C3 Complex. Inflameze Advanced centers on 250 mg of CurcuWIN curcumin complex. Inflameze Ultra has 500 mg of Curcumin C3 Complex per 2-capsule serving, with ParActin® andrographis, organic ginger root and BioPerine®.
Can I take it with Joint Solution Advanced or MSM 2000?
You can, but count the overlap. A full 4-capsule serving of Joint Solution Advanced adds 400 mg of boswellia extract, 200 mg of bromelain and 100 mg of Curcumin C3 Complex, and its label states it contains glucosamine from crab shell. MSM 2000 is a single ingredient (2,000 mg of MSM per tablet), so nothing repeats. Run any stack past your practitioner.
Is Inflameze Advanced safe to take with medication?
Ask your healthcare practitioner first, and bring the Supplement Facts panel. Piperine from Bioperine changes how the body processes some compounds, so every ingredient is worth checking against your medication list.
Keep learning
References
- Jäger R et al. Comparative absorption of curcumin formulations. Nutr J. 2014. PubMed
- Talebi S et al. Nutritional interventions for exercise-induced muscle damage: an umbrella review of systematic reviews and meta-analyses of randomized trials. Nutr Rev. 2024. PubMed
- Jäger R et al. Eight Weeks of a High Dose of Curcumin Supplementation May Attenuate Performance Decrements Following Muscle-Damaging Exercise. Nutrients. 2019. PubMed
- Sterk V et al. Effect of food intake on the bioavailability of boswellic acids from a herbal preparation in healthy volunteers. Planta Med. 2004. PubMed
- Chilelli NC et al. Curcumin and Boswellia serrata Modulate the Glyco-Oxidative Status and Lipo-Oxidation in Master Athletes. Nutrients. 2016. PubMed
- Shoba G et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998. PubMed
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
